Doch006997.1
Basic Information
- Insect
- Drosophila ochracea
- Gene Symbol
- -
- Assembly
- GCA_035044125.1
- Location
- JAWNML010000047.1:7721411-7723834[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.008 0.5 10.8 5.0 3 23 260 280 259 280 0.97 2 12 0.00011 0.0067 16.7 0.4 1 23 286 311 286 311 0.95 3 12 0.0048 0.3 11.5 0.6 1 23 318 343 318 343 0.92 4 12 0.00061 0.038 14.4 5.1 1 23 353 375 353 375 0.97 5 12 0.0002 0.013 15.8 1.8 2 23 383 404 382 404 0.96 6 12 0.0075 0.47 10.9 0.5 1 23 410 432 410 432 0.97 7 12 0.1 6.5 7.3 1.9 1 23 438 461 438 461 0.97 8 12 0.0047 0.3 11.6 3.7 1 23 467 489 467 489 0.96 9 12 0.00014 0.0085 16.4 1.2 2 23 496 517 495 517 0.98 10 12 0.0014 0.085 13.3 1.9 1 23 608 631 608 631 0.95 11 12 0.18 12 6.5 2.9 1 21 637 656 637 659 0.71 12 12 8.8e-06 0.00056 20.1 3.4 1 23 665 688 665 688 0.98
Sequence Information
- Coding Sequence
- atgaatgaggGGAGTGAATACTCCATTCACTCAATATGCCGAATCTGCTTAAATCACCTTCGAAATGATCCGGCGTACGACCTGTTTCTCGTTCCGGGTCTGGCCaaaaaactgtgtgtgtgtacttcaCTCTCAGTGGAACAGCACGATGGCTTCCCGAAAAATCTTTGCACCAATTGCTACACCAAGCTGAACGACTTGCTCGGATTCCAGAAGCTGTGCGTGGACTCTGTACAAAAGTTTCAGGAAATGGTCGCTAGCAATTATTTCGTACCCGTTGCTGGTGATATTGATAAAGTCGATATGCTTACTGGGACGCCGGTCGATGGGGAAGCGGATGACGATAACATCAACTTTGATCCGCTTCTGAATACCAAGATAGAAATTGTGAAGACTGAGGAGgatgtttttaaaatgctaGATGATGTCGACAAGGAAGCAGAGGAGGTTGAGAAGGAAGTAGAGACGGAGGTAGAGAGGGAAAAGGATACATCCAGTGATAGTGACaacgataatgataatgataatgatgacgatAGGGACGTTGACTTTCAAGTGAATAGCGACTCTGAAGACGCCGTACCCTTATCCCGCTTACGTCGTTCAACCAGAGCAAAAACTACAAAGGCCAAAACGAATACTGCGGATGACGATGAAGATGATTCCTCTAGCTTTGAATGGGCTGAGGATAAGGAGAATGACTTGGATAAACCCAAGCCAAAGCCAAGACGAAAACGCGCTCAAGTTGCTTCGACGCCCCTCGATGGACTGGTTGACTGTCACATTTGTCAGGAAAAATTCAAGAGCACCAAACTCTACGAGGAACACATGAAACATCACAACGATCAATTGCCATTCCAGTGCTCTGTTGAAGACTGCAAGAAGGGTTTCACTACGGCTGGTGGTCTGCGCCTTCATATGGACCACGCCCATTCAGAATTCTCTGAAGTGCACGCCTGCACTGCTGAGGGATGTGATAAGACCTTTCCTCGATCTGTGTTACTCACGTTCCATTTGAAAAAGGTACACAACATTATCAAGACACCGTCGCGGAATCATCCGTGCACGGAATGCGACAAAGTCTTCCGTTGTTCAACAGCACTTAAGAAGCACATGTATAAACACACTGGCGAAGAGAAGCCAATCTCCTGTAACATCTGCAACAAGCGCTTCCACATAAACAGCGATCTCAGAGATCATCTCTTGCGTCATGCCGGTGTGAAGAATCATGTGTGCCCCTACTGCGGCGTCGGTAAAACCACTCGCCAGGAGTGGAACAAACACATACTGACCCACACCAAGGAAAAACAGTTCCAGTGTCGCCAGTGCGAGCATGCTTCCCACAACAAACAAGCTTTGGCCAATCATGTCAAGGTGGTTCATATGAAGATCAAGGACTTCGCCTGTCAGTATTGCGGTAAAAAGTTCAGCATGTCGTATTCGTGCAAAGTTCACGAGAGACTCCACACGGGCGAAAACTGCAGCAAGTGCAAGATCTGTGGCAAGGTGTTTCTTTTCGAGAAGGGATTGACCAAACATTTAAAGACCCATGAGAAGCGCGATAAAACACGGTCTGCTTCTGCGATTGCAGTCAAATCGAAGGACGATGGAGTCGCGCAAGGCACAAAAAACGCTATCCAAGAATTGACTCAACCAGTGGACGGGAAAGTCGTTCCTGAAGTTTCCACCAAGCCGAAGACATCAAATAGAGTTGAGCGTGTAGATATATCGCAGCTAGCAGGCACCTCCGTCAATCCAATATCATCAGTATCGGTTCCCTCCTGGTCGCCGCAAGTCAACTTCACAAAGAAGGAAGGCCAGCATATTTGCCCAGGATGTGGACATGGTTTCAATCACATTGGCAATATGAAGCTCCACTACAAGATAATACACGAGAAGGTGAAGGACTTTGCCTGTCGATTTTGTCCGAAGCGATTTTCGAAGGCACACATATTAAAACATCATGAATGGGTTCACACTGGCGAGAAACCGTACGAGTGCAAGGTTTGCGGCAAACATTTCCGGCAGGAGTCAAGTCGGAAAAACCATTTAAGAAGAGTGCACGAGAATGCGAAACCTGCAAAGGAGCCGAGACCACCAAAGACTGTTCTTAGGCCAACTGGACCACACGTCTtgctcaacaaaaaacacgTCCTAAAGAATTTTGATGAGTACCAGGATCCTGCTGCAGAGCAAGccgctgcgactgctgcatTGCTTGCCCAACAGCAGGAAGAAAATGAAGCGAAGCGAAGGGCTGAAGAAGAAACTCGCAAGATTCAGGAGGCTGCATGTGAACAACTTCAAAGACTGCAGAAGGAGCAACTTATCGAGAAGATATCCATTAACAGCTTTCAAGTAAAAAGATCCGAATCAGGTGTCACTGTGGATGACCTCAAAGTAGATCCCACACAGAAAGAATAA
- Protein Sequence
- MNEGSEYSIHSICRICLNHLRNDPAYDLFLVPGLAKKLCVCTSLSVEQHDGFPKNLCTNCYTKLNDLLGFQKLCVDSVQKFQEMVASNYFVPVAGDIDKVDMLTGTPVDGEADDDNINFDPLLNTKIEIVKTEEDVFKMLDDVDKEAEEVEKEVETEVEREKDTSSDSDNDNDNDNDDDRDVDFQVNSDSEDAVPLSRLRRSTRAKTTKAKTNTADDDEDDSSSFEWAEDKENDLDKPKPKPRRKRAQVASTPLDGLVDCHICQEKFKSTKLYEEHMKHHNDQLPFQCSVEDCKKGFTTAGGLRLHMDHAHSEFSEVHACTAEGCDKTFPRSVLLTFHLKKVHNIIKTPSRNHPCTECDKVFRCSTALKKHMYKHTGEEKPISCNICNKRFHINSDLRDHLLRHAGVKNHVCPYCGVGKTTRQEWNKHILTHTKEKQFQCRQCEHASHNKQALANHVKVVHMKIKDFACQYCGKKFSMSYSCKVHERLHTGENCSKCKICGKVFLFEKGLTKHLKTHEKRDKTRSASAIAVKSKDDGVAQGTKNAIQELTQPVDGKVVPEVSTKPKTSNRVERVDISQLAGTSVNPISSVSVPSWSPQVNFTKKEGQHICPGCGHGFNHIGNMKLHYKIIHEKVKDFACRFCPKRFSKAHILKHHEWVHTGEKPYECKVCGKHFRQESSRKNHLRRVHENAKPAKEPRPPKTVLRPTGPHVLLNKKHVLKNFDEYQDPAAEQAAATAALLAQQQEENEAKRRAEEETRKIQEAACEQLQRLQKEQLIEKISINSFQVKRSESGVTVDDLKVDPTQKE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00498311;
- 90% Identity
- iTF_00517164;
- 80% Identity
- -