Dcyr004708.1
Basic Information
- Insect
- Drosophila cyrtoloma
- Gene Symbol
- -
- Assembly
- GCA_035042485.1
- Location
- JAWNLH010000667.1:8904224-8906656[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.0079 0.51 10.8 5.0 3 23 263 283 262 283 0.97 2 12 0.00015 0.0099 16.2 0.3 1 23 289 314 289 314 0.94 3 12 0.00074 0.048 14.1 0.6 1 23 321 346 321 346 0.93 4 12 0.0006 0.039 14.3 5.1 1 23 356 378 356 378 0.97 5 12 0.0002 0.013 15.8 1.8 2 23 386 407 385 407 0.96 6 12 0.0074 0.48 10.9 0.5 1 23 413 435 413 435 0.97 7 12 0.029 1.9 9.0 1.9 1 23 441 464 441 464 0.97 8 12 0.0046 0.3 11.5 3.7 1 23 470 492 470 492 0.96 9 12 0.00013 0.0087 16.4 1.2 2 23 499 520 498 520 0.98 10 12 0.00019 0.012 15.9 0.8 1 23 611 634 611 634 0.95 11 12 0.18 12 6.5 2.9 1 21 640 659 640 662 0.71 12 12 8.7e-06 0.00057 20.1 3.4 1 23 668 691 668 691 0.98
Sequence Information
- Coding Sequence
- atgaatgagGGGAGTGAATACTCCATTCACTCAATATGCCGAATCTGCTTAAATCACCTTCGAAATGATCCGGCGTACGACCTGTTTCTCGTTCCGGGTCTGGCCAaaaaactgtgtgtgtgtacttcaCTCTCAGTGGAACAGCACGATGGCTTCCCGAAAAACCTCTGCACCAATTGCTACACCAAGCTGAACGACTTGCACGGATTCCAGAAACTGTGCGTGGACTCTGTGCAAAAGTTTCAGGAAATGGTCGCTAGCAATTATTTCGTACCCGTTGCTGGTGATATTGATAAAGTCGATATGCTGACTGGGGCGCCGGTCGATGGGGAAGCGGATGACGATAACATAAACTTTGATCCGCTTCTGAATACCAAAATAGAAATTGTGGAGACTGAGGAGgatgtttttaaaatgctaGATGATGTCGACAAGGAAGCAGAGGAGGTTGAGAAGGAAGTAGAGAGGGAGGTAGAGAGGGCAAAAGATATATCCAGTGATGGTGACAACgacaatgataatgataatgataatgatgacgatAGGGATGTTGACTTTCAAGTGAATAGTAGCGACTCTGACGACGCCGTACCCTTGTCCCGCTTACGTAGTTCGACCAGAGCAAAAACGACAAAGGCCAAAACAAATACTGCGGATGACGATGAAGATGATTCCTCTAGCTTTGAATGGGCTGAGGATAAAGAGGATGACATGGATAAGCCCAAGCCAAAGCCAAGACGAAAACGCGCTCAAGTTGCTTCGGCACCCCTCGATGGATTGGTTGACTGTCACATTTGTCAGGAAAAGTTCAAGAGCACCAAACTCTACGAGGAACACATGAAACACCACAACGATCAATTGCCATTCCAGTGCTCTGTTGAAGAATGCAAGAAGGGTTTCACTACGGCTGGTGGCCTGCGCCTTCATATGGACCACGCCCATTCAGAGTTCTCTGAAGTGCACGCCTGCACTGCTGAGGGATGTGACAAGACCTTTCCTCGATCTGGCTTACTCACGTTCCATATGAAAAAGGTGCACAACATTATCAAGACACCGTCGCGGAATCATCCGTGCACGGAATGCGACAAAGTCTTCCGTTGTTCAACGGCACTCAAGAAGCACATGTATAAACACACTGGCGAGGAGAAGCCAATTTCCTGTAACATCTGCAACAAACGTTTTCACATAAACAGCGATCTCAGAGATCATCTTTTGCGCCATGCAGGTGTAAAGAATCATGTGTGCCCCTACTGCGGCGTCGGTAAAACCACTCGCCAGGAGTGGAACAAACACATATTGACCCACACCAAGGAAAAACAGTTCCAGTGTCGCCAGTGCGATCATGCTTCCCACAACAAACAAGCTCTGGCCAATCACGTCAAGGTGGTTCATATGAAGATCAAGGACTTCGCTTGTCAGTATTGCGGTAAAAAGTTTAGCATGTCGTATTCGTGCAAAGTTCACGAGAGACTCCACACGGGCGAGAACTGCAGCAAGTGCAAGATCTGTGGCAAGGTGTTCCTTTTCGAGAAGGGGTTGACCAAACATTTAAAGACCCATGAGAAGCGCGATAAAACACGGTCTGCTTCTGCAACTTCAGTCAAACCGAAGGACGATGGAGTCGCGCAAGGCACACATAACGCTATCCAAGAATTGACTCAGCCAGTGGACGGGAAAGTCGTTCCAGAAGTTTGCACCAAGCCGAAGACATCAAATAGAGTTCAACGTGTAGATATATCACAGCTAGCGGGCACCTCTGTCAATCCAATATCATCAGTATCGGTGCCCTCATGGTCGCCGCAAGTCAACTTCACAAAGAAGGAAGGCCAGCATATTTGCCCAGGATGTGGACGTGGTTTCAATCACATTGGCAACATGAAGCTTCACTACAAGATAATACACGAGAAGGTTAAGGACTTTGCCTGTCGCTTTTGTCCGAAGCGTTTTTCGAAGGCACACATATTAAAACATCATGAATGGGTTCACACTGGCGAGAAACCGTACGAGTGCAAGGTTTGCGGTAAACATTTTCGGCAGGAGTCAAGTCGGAAAAACCATTTGAGAAGAGTGCACGAGAATGCGAAAACTGCAAAGGACCCGAGACCACCAAAGACTGTTCTTAAGCCAACTGGACCACACGTCTtgctcaacaaaaaacacgTCCTAAAGAATTTTGATGAGTTCCAGGATCCTGCTGCAGAGCAAGccgctgcgactgctgcaTTGCTTGCCCAACAGCAGGAAGAGAATGAAGCGAAGCGAAGGGCTGAAGAAGAAACTCGCAAGATTCAGGAGGCTGCATGTGAACAACTTCAAAGGCTGCAGAAGGAGCAACTTATCGAGAAGATATCCATTAACAGCTTTCAAGTAAAAAGATCAGAATCAGGTGTCACTGTGGATGACCTGAAAGTAGATCCtacacaaaaagaataa
- Protein Sequence
- MNEGSEYSIHSICRICLNHLRNDPAYDLFLVPGLAKKLCVCTSLSVEQHDGFPKNLCTNCYTKLNDLHGFQKLCVDSVQKFQEMVASNYFVPVAGDIDKVDMLTGAPVDGEADDDNINFDPLLNTKIEIVETEEDVFKMLDDVDKEAEEVEKEVEREVERAKDISSDGDNDNDNDNDNDDDRDVDFQVNSSDSDDAVPLSRLRSSTRAKTTKAKTNTADDDEDDSSSFEWAEDKEDDMDKPKPKPRRKRAQVASAPLDGLVDCHICQEKFKSTKLYEEHMKHHNDQLPFQCSVEECKKGFTTAGGLRLHMDHAHSEFSEVHACTAEGCDKTFPRSGLLTFHMKKVHNIIKTPSRNHPCTECDKVFRCSTALKKHMYKHTGEEKPISCNICNKRFHINSDLRDHLLRHAGVKNHVCPYCGVGKTTRQEWNKHILTHTKEKQFQCRQCDHASHNKQALANHVKVVHMKIKDFACQYCGKKFSMSYSCKVHERLHTGENCSKCKICGKVFLFEKGLTKHLKTHEKRDKTRSASATSVKPKDDGVAQGTHNAIQELTQPVDGKVVPEVCTKPKTSNRVQRVDISQLAGTSVNPISSVSVPSWSPQVNFTKKEGQHICPGCGRGFNHIGNMKLHYKIIHEKVKDFACRFCPKRFSKAHILKHHEWVHTGEKPYECKVCGKHFRQESSRKNHLRRVHENAKTAKDPRPPKTVLKPTGPHVLLNKKHVLKNFDEFQDPAAEQAAATAALLAQQQEENEAKRRAEEETRKIQEAACEQLQRLQKEQLIEKISINSFQVKRSESGVTVDDLKVDPTQKE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00498311;
- 90% Identity
- iTF_00517164;
- 80% Identity
- -