Basic Information

Insect: Drosophila heteroneura
Gene Symbol: ken1
Assembly: GCA_035042245.1
Location: JAWNLO010000430.1:974872-977298[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.012 0.78 10.2 4.6 3 23 261 281 260 281 0.97

2 12 0.00015 0.0097 16.2 0.3 1 23 287 312 287 312 0.94

3 12 0.0013 0.081 13.3 0.7 1 23 319 344 319 344 0.93

4 12 0.0006 0.038 14.4 5.1 1 23 354 376 354 376 0.97

5 12 0.0002 0.013 15.8 1.8 2 23 384 405 383 405 0.96

6 12 0.0027 0.17 12.3 0.1 1 23 411 433 411 433 0.98

7 12 0.032 2 8.9 1.4 1 23 439 462 439 462 0.97

8 12 0.0048 0.3 11.5 3.2 1 23 468 490 468 490 0.96

9 12 0.00013 0.0084 16.4 1.2 2 23 497 518 496 518 0.98

10 12 0.00019 0.012 15.9 0.8 1 23 609 632 609 632 0.95

11 12 0.12 7.8 7.1 1.5 1 21 638 657 638 660 0.72

12 12 8.4e-06 0.00053 20.2 2.3 1 23 666 689 666 689 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.012	0.78	10.2	4.6	3	23	261	281	260	281	0.97
2	12	0.00015	0.0097	16.2	0.3	1	23	287	312	287	312	0.94
3	12	0.0013	0.081	13.3	0.7	1	23	319	344	319	344	0.93
4	12	0.0006	0.038	14.4	5.1	1	23	354	376	354	376	0.97
5	12	0.0002	0.013	15.8	1.8	2	23	384	405	383	405	0.96
6	12	0.0027	0.17	12.3	0.1	1	23	411	433	411	433	0.98
7	12	0.032	2	8.9	1.4	1	23	439	462	439	462	0.97
8	12	0.0048	0.3	11.5	3.2	1	23	468	490	468	490	0.96
9	12	0.00013	0.0084	16.4	1.2	2	23	497	518	496	518	0.98
10	12	0.00019	0.012	15.9	0.8	1	23	609	632	609	632	0.95
11	12	0.12	7.8	7.1	1.5	1	21	638	657	638	660	0.72
12	12	8.4e-06	0.00053	20.2	2.3	1	23	666	689	666	689	0.98

Sequence Information

Coding Sequence: atgaatgagGGGAGTGAATACTCCATTCACTCAATATGTCGAATCTGCTTAAATCACCTTCGAAATGATCCGGCGTACGACCTGTTTCTCGTTCCGGGTCTGGCCAaaaaactgtgtgtgtgtacttcaCTCTCAGTGGAACAGCACGATGGCTTCCCGAAAAACCTTTGCACCAATTGCTACACCAAGCTGAACGACTTGCATGGATTCCAGAAACTATGCGTGGACTCTGTGCAAAAGTTTCAGGAAATGGTCGCTAGCAATTATTTCGTACCCGTTGCTGGTGATATTGATAAAGTCGATATGCTGACTGGGGCGCCGGTCGATGGGGAAGCGGATGACGAAAACATCAACTTTGATCCGCTTCTGAATACCAAGATAGAAATTGTGGAAACTGAGGAGgatgtttttaaaatgctaGATGATGTCGACAAGGAAGCAGAGGAGGTTGAGAAGGAAGTAGAGAGGGAGGTAGAGAGGGCAAAGGATATATCCAGTGATAGTGACAACgacaatgataatgataatgatgacgatAGGGATGTTGACTTTCAAGTGAATAGTAGCGACTCTGACGACGCCGTTCCCCTATCCCGCTTACGTAGTTCGACcagagcaaacaaaacaaaggccAAAACAAATACTGTGGATGACGATGAAGATGATTCCTCTAGCTTTGAATGGGCTGAGGATAAGGAGGATGACATGGATAAACCCAAGCCAAAGCCAAGACGAAAACGCGCTCAAGTCGCTTCGGCACCCCTCGATGGATTGGTTGACTGTCACATTTGTCAGGAGCAATTCAAGAGCACCAAACTCTACGAGGAACACATGAAACATCACAACGATCAATTGCCATTCCAGTGCTCTGTTGAAGAATGCAAGAAGGGTTTCACTACGGCTGGTGGCCTGCGCCTTCATATGGACCACGCCCATTCAGAGTTCTCTGAAGTGCACGCCTGCACTGCTGAGGGATGCGACAAGACCTTTCCTCGATCTGTCTTACTCACGTTCCATATGAAAAAGGTGCACAACATTATCAAGACACCGTCGCGGAATCATCCGTGCACGGAATGCGACAAAGTCTTCCGTTGTTCAACGGCACTCAAGAAGCACATGTATAAACACACTGGCGAGGAGAAGCCAATCTCCTGTAACATCTGTAACAAACGTTTTCACATAAACAGCGATCTCAGAGATCATCTCTTGCGCCATGCTGGCGTGAAGAACTATGTGTGTCCGTATTGCGGCGTGGGCAAAACTACTCGTCAGGAATGGAACAAACACATACTGACCCACACCAAGGAAAAACAGTTCCAGTGTCTCCAGTGCGATCATGCCTCGCATAACAAACAGGCTCTGGCCAATCATGTCAAGGTGGTTCATATGAAGATCAAGGACTTCGCCTGTCAGTATTGCGGTAAAACGTTTGGCAAGTCGTATTCGTGCAAAGTTCACGAGAGACTCCACACGGGCGAGAACTGCAGCAAGTGCAAGATCTGTGGCAAGGTGTTCCTTTTCGAGAAGGGATTGACCAAACATTTAAAGACCCATGAGAAGCGCGATAAAACACGGTCTGCTCCTACAACTTCAGTCAAACCGAAAGACGATGGAGTCGCGCAAGGCACACAAAACGCTATCCAAGAATTGACACAGGCAGTGGACGGGAAAGTCGTTCCAGAAGTTTCCACCAAGCCGAAGTCATCAAATAGAGTTGAGCGTGTAGATATATCGCAGCTAGCGGGCACCTCTGTCAATCCAATATCATCAGTATCGGTGCCCTCATGGTCGCCGCAAGTCAACTTCACAAAGAAGGAAGGCCAGCATATTTGTCCAGGATGTGGACGTGGTTTCAATCACATTGGCAACATGAAGCTTCACTACAAGATAATACACGAGAAGGTTAAGGACTTTGCCTGTCGCTTTTGTCCGAAGCGTTTTTCGAAGGCACAAATTTTGAAACATCATGAATGGGTTCACACTGGCGAGAAACCGTACGAGTGCAAGGTTTGCGGCAAACACTTCCGACAGGAGTCAGTTATGAAGAACCATTTGAGAAGAGTGCACGAGAATGCGAAACCTGCAAAGGAGCCGAAACCACCAAAGACTGTTCTTAGGCCAACTGGACCACACGTCTtactcaacaaaaaacacgTCCTAAAGAATTTTGATGAGTTCCAGGATCCTGCTGCAGAGCAAGccgctgcgactgctgcatTGCTTGCCCAACAGCAGGAAGAGAATGAAGCGAAGCGAAGGGCTGAAGAAGAAACTCGCAAGATTCAGGAGGCTGCATGTGAACAACTTCAAAGGCTGCAAAAGGAGCAACTTATCGAGAAGATATCCATTAACAGCTTTCAAGTAAAAAGATCCGAATCAGGTGTCACTGTGGATGACCTGAAAGTAGATCCTACGCAAAAAGAATAA
Protein Sequence: MNEGSEYSIHSICRICLNHLRNDPAYDLFLVPGLAKKLCVCTSLSVEQHDGFPKNLCTNCYTKLNDLHGFQKLCVDSVQKFQEMVASNYFVPVAGDIDKVDMLTGAPVDGEADDENINFDPLLNTKIEIVETEEDVFKMLDDVDKEAEEVEKEVEREVERAKDISSDSDNDNDNDNDDDRDVDFQVNSSDSDDAVPLSRLRSSTRANKTKAKTNTVDDDEDDSSSFEWAEDKEDDMDKPKPKPRRKRAQVASAPLDGLVDCHICQEQFKSTKLYEEHMKHHNDQLPFQCSVEECKKGFTTAGGLRLHMDHAHSEFSEVHACTAEGCDKTFPRSVLLTFHMKKVHNIIKTPSRNHPCTECDKVFRCSTALKKHMYKHTGEEKPISCNICNKRFHINSDLRDHLLRHAGVKNYVCPYCGVGKTTRQEWNKHILTHTKEKQFQCLQCDHASHNKQALANHVKVVHMKIKDFACQYCGKTFGKSYSCKVHERLHTGENCSKCKICGKVFLFEKGLTKHLKTHEKRDKTRSAPTTSVKPKDDGVAQGTQNAIQELTQAVDGKVVPEVSTKPKSSNRVERVDISQLAGTSVNPISSVSVPSWSPQVNFTKKEGQHICPGCGRGFNHIGNMKLHYKIIHEKVKDFACRFCPKRFSKAQILKHHEWVHTGEKPYECKVCGKHFRQESVMKNHLRRVHENAKPAKEPKPPKTVLRPTGPHVLLNKKHVLKNFDEFQDPAAEQAAATAALLAQQQEENEAKRRAEEETRKIQEAACEQLQRLQKEQLIEKISINSFQVKRSESGVTVDDLKVDPTQKE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00498311;
90% Identity: iTF_00517164;
80% Identity: -