Dbuz001460.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila buzzatii
Gene Symbol
-
Assembly
GCA_035045845.1
Location
JAWNOS010000048.1:317858-321697[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 8e-05 0.0063 17.1 1.6 1 23 344 366 344 366 0.93
2 9 2e-08 1.6e-06 28.5 2.6 1 23 372 394 372 394 0.98
3 9 8.2e-06 0.00064 20.2 0.8 1 23 400 422 400 422 0.98
4 9 5.9e-06 0.00046 20.7 1.0 1 23 428 450 428 450 0.97
5 9 2.9e-05 0.0023 18.5 1.4 2 23 541 562 540 562 0.96
6 9 3e-09 2.4e-07 31.0 1.6 1 23 568 590 568 590 0.98
7 9 0.0037 0.29 11.9 0.9 3 23 598 618 596 618 0.97
8 9 0.0001 0.0079 16.8 0.9 1 23 624 646 624 646 0.99
9 9 0.017 1.3 9.8 1.1 1 23 653 677 653 677 0.95

Sequence Information

Coding Sequence
ATGGCCATCAATTTCTCGGCCTCCTTTGCGGCCTGCATAGCGGCGGGCCTGAAGGTGCCTCGCCAGATAATGTACTGCATTACGCAGGACACGGGCCAGCCGTACGTCCTGTACAAGGACTCGCAGGATGCGGAACGCAATGCGGGCGCCATTGGCGCCAGCGCCGCCCAATGGGGCAGCGACATGTACCCCAACATACAGCAGCAGGCACAGCAACATCTCagcgcacagcagcaacagcaacaacagcagcagcagcagcagcaacaacagcagcagcaacagcaacagcagcagcagaacgcCACAGTTGCAGcacaggcagcggcagcagctgctgctgcggcggcagcGGGTCAGCCACAGAGCCCGCCGGGCGGCCAGGAGCCGCGCGACAATGGCAGCGGCGATGgccggcagcagcaggtgtCGCCCTCCTCCAGTCCGTATCCATcggtgcagcagcaacagcagcagcgagcgaATGGCAATGCCGACGACGATGCCATGAATCAGCTTGCCAATCAACAGAACTCCGCGCCAAATCCAAACCAAAGCAGCAACGAGCCGCAGCACGCGCCCACGAATGGGGGCGAGGCTGGCCAGGGTAATCCGCATGTGCAGCAGAATGGCGGTGGGCAGCCACAGGGTGATCCGAGCAATGGATTCCAAACGCCCGACTACTATGCACCGCGTCATGGAGCGCCGCAGGGCGGCATGCTGGCGCCGCCTGGCTTCCCGCCATTGCACTACCTGAACAAGGGCGTGCTGCCCATGGAGCAGAACGGAGGCGAATCGTATGCTCTGCCCGAGCTGCTGCCcggtcagcagcagcagcagcagcaacagcagcagcagcagcagcaacaacagcagaacgGCAGCCAGCCggccaatggcaatgccaatgaGGGCGCTGCGGCGGCCAATGGCGGAGCAGCGGGCGCTGCGGGCGCCACGGGGACGACGAGCGGTCGCACAGGACCTGGCCGCCCGCACAAGAACAAGCCGCACAGCGATCTGCGGCTGTTCAAGTGCCTAACCTGCGGCAAGGACTTCAAGCAGAAGAGCACGCTGCTGCAGCACGATCGGATACATACGGATGCCCGTCCATTTCCGTGCTCCGAGTGCGGCAAGCGCTTTCGACAGCAATCGCATCTGACGCAGCATCTGCGCATCCATGCCAACGAAAAGCCATTCACCTGCCCGTACTGCTCGCGCAGCTTCCGGCAGCGAGCCATACTCAATCAGCACATACGCATCCATTCGGGTGAGAAGCCCTTCGCCTGCCCAGAGTGCGGCAAGCACTTTCGCCAGAAGGCCATCCTCAATCAGCATGTGCGCACCCACCAAGATGTCTCGCCGCATCTCATCTTCAAGAATGGACCGCATCCGACGCTCTGGCCCTCGGACGTGCCCTTTCCGGGCGAGGAAGCGGACTCGAAGGGCGACATTGCCGTCGCTGGCGGCGGCTATCATGACGACGACTCCCAGGGCACACCCGATGGCAGCGGTGGCATGCACTATCCGTCCTACTTTAAGGATGGCAAGGGTCAGAAGATACTGCCCGAGGTGCTGCAACATATTGGCGTGCGGCCGGCGAATATGCCGCTCTATGTGCGCTGTCCCATCTGCGACAAGGAGTTCAAGCAGAAGACGACGCTGCTGCAGCACGGCTGCATACACATCGAATCACGGCCGTATCCGTGCCCGGAGTGTGGCAAGCGCTTCCGCCAGCAATCGCATCTCACGCAGCATCTGCGCATCCATACGAATGAGAAGCCCTTCGGCTGCATGTACTGTCCGCGCTTCTTCCGCCAGCGAACCATACTGAATCAGCACTTACGCATTCACACTGGCGAGAAGCCCTACAAGTGCGGCCAGTGCGGCAAGGACTTCAGGCAGAAGGCCATATTGGATCAGCATACGCGCACCCACCAGGTAGGCGATCGTCCGTTCTGCTGTCCCATGCCCAATTGCCGGCGACGCTTTGCCACTGAGAACGAGGTGACGAAGCACATTGATAACCACATGAATCCCAACAGCACCAAGGTGCgtcgccagcagcaacagcagcagcagcaacagcaacaggtgcagcaggtgcagcagcaagtgcagcagcaacagcaacagcagcagcagcagcaagtgcagcagcagcaacagaatgCCGCCGCCTCGGCCGCTGTCGTTAATCATCTGATGAACGATGCCAAGAGCCTGGCCGCACAGCAATtcctcaacaacaacaatcccGCCGCTGTGGATAATAAGGCCAACATATTGCCGGTGCGCAGCATGGCAGCAaatgcggctgcagcagcagccgttgccCAGCAATCGGTGGTCAAGAATGAGCTATACTTTCCGCAGTGCTACGGCCCGCCCTTCCAGCATCCCTTCcacgcccagcagcagcagcaacagcagcagcagcagccaagtgCCGCGCACGCCAATGGACCCACGCCGCCTGTGACGGTGACCGTGGCCAGTGCGCCGGGCGTGGTGGTGCAGCAGAATGCGGCCACCTCTGTGGTGGCCCAGTGA
Protein Sequence
MAINFSASFAACIAAGLKVPRQIMYCITQDTGQPYVLYKDSQDAERNAGAIGASAAQWGSDMYPNIQQQAQQHLSAQQQQQQQQQQQQQQQQQQQQQQQQNATVAAQAAAAAAAAAAAGQPQSPPGGQEPRDNGSGDGRQQQVSPSSSPYPSVQQQQQQRANGNADDDAMNQLANQQNSAPNPNQSSNEPQHAPTNGGEAGQGNPHVQQNGGGQPQGDPSNGFQTPDYYAPRHGAPQGGMLAPPGFPPLHYLNKGVLPMEQNGGESYALPELLPGQQQQQQQQQQQQQQQQQNGSQPANGNANEGAAAANGGAAGAAGATGTTSGRTGPGRPHKNKPHSDLRLFKCLTCGKDFKQKSTLLQHDRIHTDARPFPCSECGKRFRQQSHLTQHLRIHANEKPFTCPYCSRSFRQRAILNQHIRIHSGEKPFACPECGKHFRQKAILNQHVRTHQDVSPHLIFKNGPHPTLWPSDVPFPGEEADSKGDIAVAGGGYHDDDSQGTPDGSGGMHYPSYFKDGKGQKILPEVLQHIGVRPANMPLYVRCPICDKEFKQKTTLLQHGCIHIESRPYPCPECGKRFRQQSHLTQHLRIHTNEKPFGCMYCPRFFRQRTILNQHLRIHTGEKPYKCGQCGKDFRQKAILDQHTRTHQVGDRPFCCPMPNCRRRFATENEVTKHIDNHMNPNSTKVRRQQQQQQQQQQQVQQVQQQVQQQQQQQQQQQVQQQQQNAAASAAVVNHLMNDAKSLAAQQFLNNNNPAAVDNKANILPVRSMAANAAAAAAVAQQSVVKNELYFPQCYGPPFQHPFHAQQQQQQQQQQPSAAHANGPTPPVTVTVASAPGVVVQQNAATSVVAQ