Dham017413.3


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila hamatofila
Gene Symbol
-
Assembly
GCA_035045345.1
Location
JAWNPA010000054.1:2381870-2387715[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 9.7e-05 0.0072 16.9 1.6 1 23 347 369 347 369 0.93
2 9 2.4e-08 1.8e-06 28.3 2.6 1 23 375 397 375 397 0.98
3 9 9.9e-06 0.00074 20.0 0.8 1 23 403 425 403 425 0.98
4 9 7.1e-06 0.00053 20.5 1.0 1 23 431 453 431 453 0.97
5 9 3.5e-05 0.0026 18.3 1.4 2 23 544 565 543 565 0.96
6 9 3.7e-09 2.7e-07 30.8 1.6 1 23 571 593 571 593 0.98
7 9 0.0045 0.33 11.7 0.9 3 23 601 621 599 621 0.97
8 9 0.00012 0.0091 16.6 0.9 1 23 627 649 627 649 0.99
9 9 0.02 1.5 9.6 1.1 1 23 656 680 656 680 0.95

Sequence Information

Coding Sequence
ATGGCCATCAATTTCTCGGCCTCCTTTGCGGCCTGCATAGCGGCAGGCCTGAAGGTGCCCCGCCAGATAATGTACTGCATAACGCAGGACACGGGCCAGCCGTATGTCCTGTACAAGGACTCGCAGGACGCGGAACGCAATGCAGGCGCCATCGGCGCCAGCGCCACCCAATGGGGCAGCGAGATGTACCCCAACATACAGCAGCAGGCTCAGCAACATCTCagcgcacagcagcaacagcaacagcagcagcagcagcaacaacagcagcagcaacagcaacagcagcagcagaacgcCACAGTTGCGGcccaggcagcggcagcagcagccgccgctgcgGCAGCGGGCCAACCACAGAGTCCGCCGGGCGGCCAGGAGCCACGGGACAATGGCAGCGGCGATGgccggcagcagcaggtgtCGCCCTCCTCCAGTCCGTATCCATcggtgcagcagcaacagcagcagcgaacgAATGGCAATGCCGACGACGATGCCATGAATCAGCTTGCCAATCAACAGAACTCCGCGCCAAATCCAAACCAAAGCAGCAACGAGCCGCAGCACGCGCCCACGAATGGGGGCGAGGCTGGTCAGGGTAATCCGCATGTGCAGCAGAATGGCGGTGGGCAGCCACAGGGTGATCCGAGCAACGGCTTCCAGACGCCCGACTACTATGCGCCGCGCCATGGAGCGCCGCAGGGCGGCATGCTGGCGCCACCTGGCTTCCCGCCGCTGCACTATCTGAACAAGGGCGTGCTGCCCATGGAGCAGAACGGAGGCGAGTCTTATGCGCTGCCCGAGCTGCTGCccggtcagcagcagcagcagcagcagcagcaacagcagcagcaacagaacgGAGCCCAGCCGAATGGCGGACAGAACGGCGGCCCGgccaatggcaatgccaatgagGGCGCAGCGGCGCCCAATGGCGGAGCCGCTGGCGCTGCGGGCGCCACGGGGACGACGAGCGGTCGCACGGGACCCGGCCGCCCGCACAAGAACAAGCCGCACAGCGATCTGCGGCTGTTCAAGTGCCTCACCTGCGGCAAGGACTTCAAGCAGAAGAGCACACTGCTGCAGCACGATCGGATACATACGGATGCCCGTCCATTTCCGTGCTCCGAGTGCGGCAAGCGATTCCGGCAGCAGTCGCATCTGACGCAGCATCTGCGCATCCATGCCAACGAAAAGCCATTCACCTGCCCGTACTGCTCGCGCAGCTTCCGGCAGCGAGCCATACTCAATCAGCACATACGCATCCATTCGGGTGAGAAGCCCTTCGCCTGCCCCGAGTGCGGCAAGCACTTTCGCCAGAAGGCCATCCTCAATCAGCATGTGCGCACCCACCAAGATGTCTCGCCGCATCTCATCTTCAAGAACGGACCCCATCCGACGCTCTGGCCCTCGGACGTGCCCTTTCCGGGCGAGGAGGCGGACTCGAAGGGCGACATTGCCGTCGCTGGCGGCGGCTATCATGACGACGACTCGCAGGGCACACCCGACGGCAGCGGTGGCATGCACTACCCGTCCTACTTCAAGGATGGCAAGGGTCAAAAGATACTGCCCGAGGTGCTGCAACATATTGGTGTGCGGCCGGCGAATATGCCGCTCTACGTGCGCTGCCCCATCTGCGACAAGGAGTTCAAGCAGAAGACGACGCTGCTGCAGCACGGCTGCATACACATCGAATCCCGGCCATACCCATGTCCGGAGTGCGGCAAGCGTTTCCGCCAGCAATCGCATCTCACGCAGCATCTGCGCATCCATACGAATGAGAAGCCCTTCGGCTGCATGTACTGTCCGCGCTTCTTCCGCCAGCGAACCATTCTGAATCAGCACTTACGCATTCACACTGGCGAGAAGCCCTACAAGTGCGGCCAGTGTGGCAAGGACTTCAGGCAGAAGGCTATACTGGATCAGCATACGCGCACCCACCAGGTAGGCGATCGTCCGTTCTGCTGTCCCATGCCCAATTGCCGGCGACGCTTTGCCACGGAGAACGAGGTGACGAAGCACATTGACAACCACATGAATCCCAACAGCACCAAGGTgcgccggcagcagcaacaacagcagcagcagcagcaacaggtgcAGCAGGTGCAAcagcaagtgcagcagcaacagcagcagcagcaggtgcaacagcagcaacagaatgcCGCCGCCTCGGCTGCTGTGGTCAATCATCTGATGAACGATGCCAAGAGCCTGGCCGCGCAGCAAttcctcaacaacaacaatcccGCCGCCGTGGACAACAAGGCCAACATATTGCCGGTGCGCAGCATGGCAGCGAatgcggcggcagcagcagccgttgctCAGCAGTCGGTGGTCAAGAATGAGCTATACTTTCCGCAGTGCTACGGCCCGCCCTTCCAGCATCCCTTccacgcccagcagcagcagcaacagcagcagcagcagcccagcgCCGCGCACGCCAATGGACCCACGCCGCCTGTGACGGTGACGGTGGCCAGTGCGCCGGGCGTGGTGGTGCAGCAGAATGCGGCCACCTCTGTGcagcagcaacagcagcaacaacagcaacagcagcagcaacaacagcagcaacagcaacagcagcagcaacaacaacagcagcagcaacaacaatcggtggtggcaacaacaacagcgcatCATCCGCCGCCACCGGCGCCGCCAACAAGTGCGCATCATATCACGGCCACGGGCGTTGCAACTGCCCCGCCCACATCGACACACGCCCCCACGGTGGCGGCGCCGCAAACGGTGACGCTGTCAATAAcattgccgccgccgccaccgccaacGGCGCATCCGGCGCACACGCATGCAGGACATGCACTGGCGGCCACGCCCAACGGCGTcgcgccaccaccgccgccgcccacACTGTCGCACGCGATACCCATCCACCCGCACATACACTCGATATTCGGATCTCTATGA
Protein Sequence
MAINFSASFAACIAAGLKVPRQIMYCITQDTGQPYVLYKDSQDAERNAGAIGASATQWGSEMYPNIQQQAQQHLSAQQQQQQQQQQQQQQQQQQQQQQNATVAAQAAAAAAAAAAAGQPQSPPGGQEPRDNGSGDGRQQQVSPSSSPYPSVQQQQQQRTNGNADDDAMNQLANQQNSAPNPNQSSNEPQHAPTNGGEAGQGNPHVQQNGGGQPQGDPSNGFQTPDYYAPRHGAPQGGMLAPPGFPPLHYLNKGVLPMEQNGGESYALPELLPGQQQQQQQQQQQQQQNGAQPNGGQNGGPANGNANEGAAAPNGGAAGAAGATGTTSGRTGPGRPHKNKPHSDLRLFKCLTCGKDFKQKSTLLQHDRIHTDARPFPCSECGKRFRQQSHLTQHLRIHANEKPFTCPYCSRSFRQRAILNQHIRIHSGEKPFACPECGKHFRQKAILNQHVRTHQDVSPHLIFKNGPHPTLWPSDVPFPGEEADSKGDIAVAGGGYHDDDSQGTPDGSGGMHYPSYFKDGKGQKILPEVLQHIGVRPANMPLYVRCPICDKEFKQKTTLLQHGCIHIESRPYPCPECGKRFRQQSHLTQHLRIHTNEKPFGCMYCPRFFRQRTILNQHLRIHTGEKPYKCGQCGKDFRQKAILDQHTRTHQVGDRPFCCPMPNCRRRFATENEVTKHIDNHMNPNSTKVRRQQQQQQQQQQQVQQVQQQVQQQQQQQQVQQQQQNAAASAAVVNHLMNDAKSLAAQQFLNNNNPAAVDNKANILPVRSMAANAAAAAAVAQQSVVKNELYFPQCYGPPFQHPFHAQQQQQQQQQQPSAAHANGPTPPVTVTVASAPGVVVQQNAATSVQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSVVATTTAHHPPPPAPPTSAHHITATGVATAPPTSTHAPTVAAPQTVTLSITLPPPPPPTAHPAHTHAGHALAATPNGVAPPPPPPTLSHAIPIHPHIHSIFGSL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00509959;
90% Identity
iTF_00493805;
80% Identity
-