Basic Information

Insect: Drosophila hydei
Gene Symbol: -
Assembly: GCA_003285905.2
Location: NW:5771703-5803202[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 6.7e-05 0.0038 17.1 1.6 1 23 342 364 342 364 0.93

2 9 1.7e-08 9.5e-07 28.5 2.6 1 23 370 392 370 392 0.98

3 9 6.9e-06 0.00039 20.3 0.8 1 23 398 420 398 420 0.98

4 9 4.9e-06 0.00028 20.7 1.0 1 23 426 448 426 448 0.97

5 9 2.4e-05 0.0014 18.5 1.4 2 23 540 561 539 561 0.96

6 9 2.6e-09 1.5e-07 31.1 1.6 1 23 567 589 567 589 0.98

7 9 0.0031 0.18 11.9 0.9 3 23 597 617 595 617 0.97

8 9 8.5e-05 0.0049 16.8 0.9 1 23 623 645 623 645 0.99

9 9 0.014 0.79 9.9 1.1 1 23 652 676 652 676 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	6.7e-05	0.0038	17.1	1.6	1	23	342	364	342	364	0.93
2	9	1.7e-08	9.5e-07	28.5	2.6	1	23	370	392	370	392	0.98
3	9	6.9e-06	0.00039	20.3	0.8	1	23	398	420	398	420	0.98
4	9	4.9e-06	0.00028	20.7	1.0	1	23	426	448	426	448	0.97
5	9	2.4e-05	0.0014	18.5	1.4	2	23	540	561	539	561	0.96
6	9	2.6e-09	1.5e-07	31.1	1.6	1	23	567	589	567	589	0.98
7	9	0.0031	0.18	11.9	0.9	3	23	597	617	595	617	0.97
8	9	8.5e-05	0.0049	16.8	0.9	1	23	623	645	623	645	0.99
9	9	0.014	0.79	9.9	1.1	1	23	652	676	652	676	0.95

Sequence Information

Coding Sequence: ATGGCCATCAACTTCTCGGCCTCGTTTGCGGCCTGCATAGCAGCGGGCCTGAAGGTGCCCCGCCAGATAATGTACTGCATTACGCAGGACACGGGCCAGCCGTACGTGCTGTACAAGGACTCGCAGGACGCGGAACGCAATGCGGGCGCCATTGGCGCCAGTGCCGCCCAATGGGGCAGCGACATGTACCCCAACatacagcagcaggcgcagcaaCATCTCagcgcacagcagcagcagcaacagcagcagcagcagcagcaacaacagcagcaacagcagcagcagcagcagaacgcCACAGTTGCCGCAcaggcagcggcggcggcagcagctgctgcagcagcgggcCAGCCACAGAGTCCGCCGGGCGGCCAAGAGGCGCGCGACAATGGCAGCGGCGATGGCCGCCAGCAGCAGGTGTCGCCCTCCTCCAGTCCGTATCCTtcggtgcagcagcagcagcagcagcgagcgaATGGCAAtgccgacgacgacgccaTGAATCAGCTTGCCAATCAACAAAACTCCGCGCCAAATCCAAACCAAAGCAGCAACGAGCCGCAGCACGCGCCCACGAACGGCGGCGAGGCTGGACAGGGTAATCCGCATGTGCAGCAGAATGGCGGCGGGCAGCCGCAGGGCGATCCGAGCAACGGCTTCCAGACGCCCGACTACTATGCGCCGCGCCATGGGGCGCCGCAGGGCGGCATGCTGGCGCCACCCGGCTTCCCGCCGTTGCACTATCTGAACAAGGGCGTGCTGCCCATGGAGCAGAACGGCGGCGAGTCGTATGCGCTGCCCGAGCTGCTGcccggccagcagcagcagcagcagcaacagcagcagcagcagcagaatggCGCACAGGCGAACGGCGGCCCGGCgaatggcaatgccaatgaGGGCGCAGCGGCGCCCAATGGCGGAGCGGCGGGCGCGGCGGGCGCCACGGGGACGACGAGCGGTCGCACGGGACCTGGCCGCCCGCACAAGAACAAGCCGCACAGCGACTTGCGGCTGTTCAAGTGCCTCACCTGCGGCAAGGACTTCAAGCAGAAGAGCACGCTGCTGCAGCACGATCGGATACATACGGACGCCCGTCCATTTCCGTGCTCCGAGTGCGGCAAGCGCTTCCGACAGCAGTCGCATCTGACGCAGCATCTGCGCATCCACGCCAACGAAAAGCCATTCACCTGCCCGTACTGCTCGCGCAGCTTCCGGCAGCGAGCCATACTCAACCAGCACATACGCATCCATTCGGGTGAGAAGCCCTTCGCCTGCCCCGAGTGCGGCAAGCACTTTCGCCAGAAGGCCATCCTCAATCAGCATGTGCGCACCCACCAAGATGTCTCGCCGCATCTCATCTTCAAGAACGGACCCCACCCGACGCTCTGGCCCTCGGACGTGCCCTTTCCGGGCGAGGAGGCGGACTCGAAGGGCGACATTGCCGTCGCTGGCGGCGGCTACCATGACGACGACTCGCAGGGCACACCCGACGGCAGCGGTGGCATGCACTATCCGTCCTACTTCAAGGACGGCAAGGCAGGCCAAAAGATACTGCCCGAGGTGCTGCAGCATATTGGCGTGCGGCCGGCGAATATGCCGCTCTACGTGCGCTGCCCCATCTGCGACAAGGAGTTCAAGCAGAAGAcgacgctgctgcagcacgGCTGCATACACATCGAGTCCCGGCCGTACCCCTGCCCGGAGTGTGGCAAGCGCTTCCGCCAGCAATCGCATCTCACGCAGCATCTGCGGATTCACACGAACGAAAAGCCCTTCGGCTGCATGTACTGTCCGCGCTTCTTCCGCCAGCGAACCATTCTGAATCAGCACTTGCGCATTCACACCGGCGAGAAGCCCTACAAGTGCGGCCAGTGCGGCAAGGACTTCAGGCAGAAGGCCATACTGGATCAGCACACGCGCACCCACCAGGTAGGCGATCGTCCGTTCTGCTGTCCCATGCCCAATTGCCGGCGACGCTTTGCCACCGAGAACGAGGTGACGAAGCACATCGACAACCACATGAATCCCAACAGCACCAAGGTgcgccggcagcagcaacagcagcagcagcagcagcagcaggtgcagcaggtccagcagcaggtgcagcagcagcagcagcagcagcaggtgcaacagcagcagcagaatgcAGCCGCCTCGGCGGCCGTCGTCAATCATCTGATGAACGATGCCAAGAGCCTGGCCGCGCAGCAATtcctcaacaacaacaatcccGCCGCTGTCGACAACAAGGCCAACATCTTGCCGGTGCGCAGCATGGCGGCGAatgcggctgcggcagcggcagttgCCCAGCAGTCGGTGGTCAAGAATGAGCTATACTTTCCGCAGTGCTACGGCCCGCCCTTCCAGCATCCCTTccacgcccagcagcagcagcagcaacagcagcagccgagcgCAGCGCACGCCAATGGACCCACGCCGCCTGTCACGGTCACCGTGGCCAGTGCACCTGGCGTTGTGGTGCAGCAGAATGCGGCCACCTCTGTGGTGGCCCAGTGA
Protein Sequence: MAINFSASFAACIAAGLKVPRQIMYCITQDTGQPYVLYKDSQDAERNAGAIGASAAQWGSDMYPNIQQQAQQHLSAQQQQQQQQQQQQQQQQQQQQQQNATVAAQAAAAAAAAAAAGQPQSPPGGQEARDNGSGDGRQQQVSPSSSPYPSVQQQQQQRANGNADDDAMNQLANQQNSAPNPNQSSNEPQHAPTNGGEAGQGNPHVQQNGGGQPQGDPSNGFQTPDYYAPRHGAPQGGMLAPPGFPPLHYLNKGVLPMEQNGGESYALPELLPGQQQQQQQQQQQQQNGAQANGGPANGNANEGAAAPNGGAAGAAGATGTTSGRTGPGRPHKNKPHSDLRLFKCLTCGKDFKQKSTLLQHDRIHTDARPFPCSECGKRFRQQSHLTQHLRIHANEKPFTCPYCSRSFRQRAILNQHIRIHSGEKPFACPECGKHFRQKAILNQHVRTHQDVSPHLIFKNGPHPTLWPSDVPFPGEEADSKGDIAVAGGGYHDDDSQGTPDGSGGMHYPSYFKDGKAGQKILPEVLQHIGVRPANMPLYVRCPICDKEFKQKTTLLQHGCIHIESRPYPCPECGKRFRQQSHLTQHLRIHTNEKPFGCMYCPRFFRQRTILNQHLRIHTGEKPYKCGQCGKDFRQKAILDQHTRTHQVGDRPFCCPMPNCRRRFATENEVTKHIDNHMNPNSTKVRRQQQQQQQQQQQVQQVQQQVQQQQQQQQVQQQQQNAAASAAVVNHLMNDAKSLAAQQFLNNNNPAAVDNKANILPVRSMAANAAAAAAVAQQSVVKNELYFPQCYGPPFQHPFHAQQQQQQQQQPSAAHANGPTPPVTVTVASAPGVVVQQNAATSVVAQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00509959;
90% Identity: iTF_00493805;
80% Identity: -