Dazt013708.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila azteca
Gene Symbol
Hr39
Assembly
GCA_005876895.1
Location
VCKU01000088.1:419770-423052[-]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 0.46 3.8e+03 -3.2 0.7 131 157 31 57 6 74 0.55
2 4 2 1.7e+04 -8.3 10.7 53 157 275 379 168 402 0.55
3 4 2.4e-10 2e-06 27.4 0.0 1 34 481 514 481 530 0.82
4 4 8.7e-87 7.2e-83 279.2 6.3 85 408 520 811 512 811 0.88

Sequence Information

Coding Sequence
atgccGAATATGTCTAGCATTAAGGCCGAGCAGCAGAGTGCCCCAATGGGGGGCACGGGCGGCTATCAACTGCCCGTGAACATGTGCACCaccagcggcggcagcagcaacagcacgacgatgacgacgacgacgacaggATCGGCGACGCCATCACGTCACAATGTGTCCGTGACGAACATCAAATGTGAACTGGAGGAGCTTCCCACGCCGAACGGCAACCTGGTGCCGGTCATCGCCAACTACAATCACGGCAGCCTCAGGATACCCCTGAGTGGGCAGCCGCACAACGTGGAGGAGGAGTCCGATTCCGAGGCGGAGCTCACGAACATCGAGAACCTGAAGGTGCGCCGGCGAGCGGCGGACAAGAACGGACCCCGACCCATGTCCTGGGAGGGAGAACTGAGCGAACCCGAGGAGaacggcggcagcggcggggGCGGCGGAGCAGAGCTGATGGAAACGGAGACGGTGATCAAGAGTGAGGTGTGCACCACGTCGACGCCCATTCAGGCGGCGTCCACCACCTGCCCGACGATGCAACCGATCAAAACGGAGCTGGACAACATTGCCGGAGAGATGCAGCATCATCCGCGAAGCAACGCCTATCCGGTGTCCAGCTGCAATGGTCCCGCGAAACTGAAGCTGGCGCCCACCCAGAGCGACCCGATCAATCTCAAGTATGAGCCCCCGCTGGGGGACAACAACTCCCCGCTGCTGACGACCCGCAACAAGTCGAACAGCGGGGGACACCTGCCGCTGCCAGCGAATCCCAGTCCCGACTCTGCCATACATTCCGTCTACACCCACAGCTCACCGTCGCAGTCGCCGCTGACGTCGCGGCATGCCCCATACACGCCGTCGCTGAGTCGCAACAACAGCGATGCCTCGCACAGCAGctgctacagctacagctcgGAGTTCAGTCCGACCCATTCGCCGATTCAGGCGCGACACGCCCCGCCGGCAGGATCCATGTACCCGGGCAGCGGATCCGCGGGAGCCAACGGAGGAGCCGCAAGCAGCTATGGGAATGGTGTGCATCATCATGGGATGCTGTACAGGCCGCTCAAAGTGGAGGCTGCCTCCTCAACGTCAACGGGAGGATCGAGCCAGGAGTCGGCACAAAATCTCAGCATGGACTCGGCTTCCAGTGCCATGGATCCGCTGGGATCGGGCTCGTTGCCCGCCTCCCCGGCTGGGATCTCCCGCCAGCAGCTGATCAACTCCCCCTGTCCGATCTGTGGGGATAAGATCAGCGGCTTTCACTATGGCATCTTCTCCTGCGAGTCCTGCAAGGGTTTCTTCAAGCGCACCGTCCAGAATCGCAAGAACTATGTGTGCGTCCGTGGGGGACCCTGCCAGGTGAGCATTTCCACGCGGAAAAAGTGCCCTGCCTGTCGGTTCGAGAAGTGCCTGCAGAAGGGCATGAAACTGGAGGCCATACGCGAGGATCGCACCCGTGGCGGTCGCTCCACCTATCAATGCTCCTACACGCTGCCCAATTCGATGCTGAGTCCGCTCCTGACGAGTCCCAGCCTGGGGGGAGCATCCATCAAAACAGAGGAATCCGAAGCAAAGACGTTAAGAGCGAGCAGTATTCCAACGCTATTGCAGgaaatcatggATGTTGAACATCTTTGGCAGTACACCGATGCAGAGCTGGCCCGCATCAATCAGCCATTGTCCTCCTTTGCCTCTGCCGGCAGCTCCTCATCATCGTCGCCTGCCTCGGCGGCACACCAGAaccaccaacagcagcaacagcagcagcagcatcagcagcaacaattgACCAATCCACTGCTGGCCAGTGCCGGTCTCTCATCCAATGGGGAGAATGCCAATCCCGATCTGATTGCCCATCTCTGCAATGTGGCCGATCATCGTCTCTACAAGATTGTCAAATGGTGCAAGAGTCTTCCCCTTTTTAAGAACATTTCGATTGATGATCAAATCTGTTTGCTGATCAATTCCTGGTGCGAACTGCTGCTCTTCTCCTGCTGTTTTCGTTCGATTGATACGCCCGGCGAGATAAAGATGTCACAAGGCAGAAAGATAACACTATCACAGGCCAAAACGAATGGCCTTCAGACCTGCATCGAACGCATGCTCAATCTGACGGATCATTTGAGGCGCCTGCGCGTGGATCGCTACGAATATGTTGCCATGAAGGTGATAGTGCTGCTGCAGTCAGACACCACAGAGCTGCAGGAGGCGGTGAAAGTGCGGGAGTGCCAGGAGAAGGCATTGCAGGGCCTGCAGGCCTACACGCTGGCCCACTATCCGGATACGCCGTCCAAGTTTGGAGAGCTACTGCTGCGTATACCCGACCTGCAGCGCACCTGTCAGCTGGGCAAAGAAATGCTGACGATCAAGACACGCGATGGAGCTGATTTCAATCTGCTGATGGAGCTGTTGCGCGGAGAACATTGA
Protein Sequence
MPNMSSIKAEQQSAPMGGTGGYQLPVNMCTTSGGSSNSTTMTTTTTGSATPSRHNVSVTNIKCELEELPTPNGNLVPVIANYNHGSLRIPLSGQPHNVEEESDSEAELTNIENLKVRRRAADKNGPRPMSWEGELSEPEENGGSGGGGGAELMETETVIKSEVCTTSTPIQAASTTCPTMQPIKTELDNIAGEMQHHPRSNAYPVSSCNGPAKLKLAPTQSDPINLKYEPPLGDNNSPLLTTRNKSNSGGHLPLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHAPPAGSMYPGSGSAGANGGAASSYGNGVHHHGMLYRPLKVEAASSTSTGGSSQESAQNLSMDSASSAMDPLGSGSLPASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLLTSPSLGGASIKTEESEAKTLRASSIPTLLQEIMDVEHLWQYTDAELARINQPLSSFASAGSSSSSSPASAAHQNHQQQQQQQQHQQQQLTNPLLASAGLSSNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSIDTPGEIKMSQGRKITLSQAKTNGLQTCIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTTELQEAVKVRECQEKALQGLQAYTLAHYPDTPSKFGELLLRIPDLQRTCQLGKEMLTIKTRDGADFNLLMELLRGEH