Basic Information

Insect: Drosophila obscura
Gene Symbol: Hr39
Assembly: GCA_018151105.1
Location: NW:7073038-7102334[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.26 1.9e+03 -2.4 0.8 142 160 25 43 3 93 0.54

2 3 2 1.4e+04 -5.5 6.7 61 153 172 290 149 325 0.43

3 3 3e-106 2.2e-102 343.3 10.5 1 408 484 873 484 873 0.87

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.26	1.9e+03	-2.4	0.8	142	160	25	43	3	93	0.54
2	3	2	1.4e+04	-5.5	6.7	61	153	172	290	149	325	0.43
3	3	3e-106	2.2e-102	343.3	10.5	1	408	484	873	484	873	0.87

Sequence Information

Coding Sequence: atgccGAATATGTCTAGCATTAAGGCTGAGCAGCAGAGTGCCCCAATGGGGGGCACGAGTAGCTATCAACTGCCCGTGAATAtgtgcaccagcagcagcagcagcaccaccacgacGACGTCGATGCCATCACGTCACAATGTGTCCGTGACGAATATTAAATGTGAACTGGAGGAGCTGCCCACGCCGAATGGCAATCTGGTGCCGGTCATCGCCAACTATAATCATGGCAGCCTAAGGATACCGCTCAGTGGGCAGCCGCACAaccagcaggaggaggaggagtccgACTCCGAGGCGGAACTCACGAATATCGAGAACCTGAAGGTGCGCCGGCGAGCGGCGGATAAGAACGGACCACGGCCCATGTCCTGGGAGGGAGAACTGAGTGAACCCGAGGAGAACGGCGTCAGTGGCAGCGGTGGCATCGGCGGGGCAGAGCTGATGGAAACGGAGACGGTGATCAAGAGTGAGGTGTGCACCACAACGTCCACGCCCATTCAGGCGTCGTCCACCACCTGCCCCACGATGCAACCGATCAAAACGGAGCTGGAGAACATTGCCGGAGAGCTGCAGCATCCGCGCAGCAACGCCTATCCGGTGTCCAGCTGCAATGGTCCCGCCAAACTGAAGCTGGCGCCCACCCAGAGCGATCCGATCAATCTCAAGTATGAGCCCCCGCTGGGGGACAACAACTCGCCGCTGCTGACGACGCGCAACAAGTCGAACAGCGGGGGACACCTGCCGCTGCCAGCGAACCCCAGTCCCGACTCTGCCATACATTCCGTCTACACCCACAGCTCACCGTCGCAGTCGCCGCTGACGTCGCGGCATGCCCCATACACGCCGTCGCTGAGTCGCAACAACAGCGATGCCTCGCACAGCagctgctacagctacagctcggAGTTCAGTCCGACACACTCGCCGATTCAGGCGCGGCATGCCCCACCAGCGGGAGCCATGTATCCGGGCAGCGGCTCCGCGGGCGTAAacggagcaggcagcagctacGGGAATGGTGTGCATCATCACGGGATGCTGTACAGGCCGCTCAAGGTGGAGGCCTCCCCAACGGTCGGATCGGTTGGCGGTGGCGCTGGCGGTGGCTCTTGCAGCCAGGAGTCGGCACAAAATCTCAGCATGGACTCTGCCTCCAGCGGCTCCATGGATCCGCTGGGATCGGGCTCGCTGCCCGCCTCGCCGGCTGGCATCTCCCGCCAGCAGCTGATCAACTCCCCCTGTCCGATCTGCGGCGATAAGATCAGTGGCTTCCACTACGGCATCTTCTCCTGCGAGTCCTGCAAGGGTTTCTTCAAGCGCACCGTCCAGAATCGCAAGAATTATGTGTGCGTACGCGGCGGTCCCTGCCAGGTGAGCATTTCCACGCGCAAAAAATGCCCCGCCTGCCGGTTCGAGAAGTGCCTGCAAAAGGGCATGAAACTGGAGGCCATACGCGAGGATCGCACCCGTGGCGGTCGCTCCACCTATCAATGCTCCTACACGCTGCCCAATTCCATGTTGAGTCCGCTCTTGAGTCCCGATCAGGCGgcggcagccgctgcagcagcatcagcggccaatcatcagcaccagcatcagcaccagcaacatcatcagcatcagcatcaacagcagagACTCCAACAGCAGATGAATGGCTACTCGGGGTCCACATCGCTGCCAGCGAGTCCCAGTCTGGGGGGGGCATCCATCAAAACGGAGGAAAACGAGTCCAAGACGCTAAGAGCCAGTAGTATTCCAACGCTATTGCAGGAAATCATGGATGTTGAACATCTTTGGCAGTACACCGATGCAGAGCTGGCCCGCATCAATCAGCCCTTGTCCGCCTTTGCCACTGGTGGCAgctcctcatcatcatcgtcgtcgtcgtcgtctgtgGCATCAACGGCACACCAGaaccaccaacagcagcagcagcagcaacagcaacagcagcagcatcagcagcaacaattgacCAATCCACTGCTGGCCAGTGCTGGTCTCTCATCCAACGGCGAGAATGCCAATCCCGATCTGATTGCACACCTCTGCAATGTGGCCGATCATCGCCTCTATAAGATTGTCAAATGGTGCAAGAGTCTTCCCCTATTTAAGAACATTTCGATTGATGATCAAATTTGTCTGCTCATCAATTCGTGGTGCGAACTGTTGCTCTTCTCGTGCTGTTTTCGGTCGATTGATACGCCCGGCGAGATAAAGATGTCACAAGGCAGAAAGATAACACTATCACAGGCCAAAACGAATGGTCTTCAGACCTGCATCGAACGCATGCTCAATCTGACGGATCATTTGAGGCGCCTGCGCGTGGATCGCTACGAATATGTCGCCATGAAGGTGATAGTGCTGCTGCAGTCAGATACCACAGAGCTGCATGAGGCGGTGAAAGTACGCGAGTGCCAGGAGAAGGCATTGCAGGGGCTGCAGGCCTACACGCTGGCCCACTATCCGGATACGCCCTCAAAGTTtggggagctgctgctgcgcatACCCGACCTGCAGCGCACCTGTCAGCTGGGCAAAGAAATGCTGACGATCAAGACACGCGATGGAGctgatttcaatttgctgaTGGAGCTGTTGCGCGGAGAACATTGA
Protein Sequence: MPNMSSIKAEQQSAPMGGTSSYQLPVNMCTSSSSSTTTTTSMPSRHNVSVTNIKCELEELPTPNGNLVPVIANYNHGSLRIPLSGQPHNQQEEEESDSEAELTNIENLKVRRRAADKNGPRPMSWEGELSEPEENGVSGSGGIGGAELMETETVIKSEVCTTTSTPIQASSTTCPTMQPIKTELENIAGELQHPRSNAYPVSSCNGPAKLKLAPTQSDPINLKYEPPLGDNNSPLLTTRNKSNSGGHLPLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHAPPAGAMYPGSGSAGVNGAGSSYGNGVHHHGMLYRPLKVEASPTVGSVGGGAGGGSCSQESAQNLSMDSASSGSMDPLGSGSLPASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLLSPDQAAAAAAAASAANHQHQHQHQQHHQHQHQQQRLQQQMNGYSGSTSLPASPSLGGASIKTEENESKTLRASSIPTLLQEIMDVEHLWQYTDAELARINQPLSAFATGGSSSSSSSSSSSVASTAHQNHQQQQQQQQQQQQHQQQQLTNPLLASAGLSSNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSIDTPGEIKMSQGRKITLSQAKTNGLQTCIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTTELHEAVKVRECQEKALQGLQAYTLAHYPDTPSKFGELLLRIPDLQRTCQLGKEMLTIKTRDGADFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00484464;
90% Identity: iTF_00473807;
80% Identity: iTF_00563960;