Dalg008384.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila algonquin
Gene Symbol
Hr39
Assembly
GCA_035041765.1
Location
JAWNKY010001621.1:777426-783581[-]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 0.11 1.1e+03 -1.2 1.4 129 159 29 59 3 84 0.58
2 3 0.44 4.5e+03 -3.1 6.3 55 160 263 368 159 398 0.62
3 3 5.4e-103 5.4e-99 332.6 15.1 1 408 467 847 467 847 0.85

Sequence Information

Coding Sequence
atgccgAATATGTCTAGCATTAAGGCCGAGCAGCAGAGTGCCCCAATGGGGGGCACGGGCAGCTATCAACTACCCGTCAATAtgtgcaccaccagcagcggcagcagcaacagcacgacgatgacgatgacgacgacaggATCGGCGACGCCATCACGTCACAACGTGTCCGTGACGAACATCAAATGTGAACTAGAGGAGCTTCCCACGCCGAATGGCAACCTGGTGCCGGTCATCGCCAACTACAATCACGGCAGCCTGAGGATACCCCTGAGTGGGCAGCCGCACAACGTGGAGGAGGAGTCCGATTCGGAGGCGGAGCTCACGAATATCGAGAACCTGAAGGTGCGCCGGCGAGCGGCGGATAAGAACGGACCCCGGCCCATGTCCTGGGAGGGAGAACTGAGCGAGCCCGAGGAgaacggcggcagcggcggtggcggcggcggcggagcaGAGCTGATGGAAACGGAGACGGTGATCAAGAGTGAGGTGTGCACCACGTCGACGCCCATCCAGGCGGCGTCCACCACCTGCCCGACGATGCAACCGATCAAAACGGAGCTGGACAACATTGCCGGAGAGCTGCAGCATCATCCGCGAAGCAACGCCTATCCGGTGTCCAGCTGCAATGGTCCCGCGAAACTGAAGCTGGCGCCCACCCAGAGCGATCCGATCAATCTCAAGTACGAGCCCCCGCTGGGGGACAACAACTCCCCGCTGCTGACGACCCGCAACAAGTCGAACAGCGGGGGACACCTGCCGCTGCCAGCGAACCCCAGTCCCGACTCTGCCATACATTCCGTCTACACCCACAGCTCACCGTCGCAGTCGCCGCTGACGTCGCGGCATGCACCGTACACGCCGTCGCTGAGCCGCAACAACAGCGATGCCTCGCACAGCAGttgctacagctacagctcggAGTTCAGTCCGACACATTCGCCGATTCAGGCGCGACACGCCCCGCCAGCAGGATCCATCTATGGGAATGGTGTGCATCATCATGGGATGCTGTACAGGCCGCTCAAAGTGGAGGCTGCCTCCTCAACGTCAACGGGAGGATCGAGCCAGGAGTCGGCGCAAAATCTCAGCATGGACTCGGCTTCCAGTGCCATGGATCCGCTGGGATCGGGCTCGTTGCCCGCCTCCCCGGCCGGGATCTCCCGCCAGCAGCTGATCAACTCCCCCTGTCCGATCTGTGGGGACAAGATCAGTGGCTTTCACTATGGCATCTTCTCCTGCGAGTCCTGCAAGGGTTTCTTCAAGCGCACCGTCCAGAATCGCAAGAACTATGTGTGCGTCCGTGGGGGACCCTGCCAGGTGAGCATTTCCACGCGGAAAAAGTGTCCCGCCTGTCGGTTCGAGAAGTGCCTGCAGAAGGGCATGAAACTGGAGGCCATACGCGAGGATCGCACCCGTGGCGGTCGCTCCACCTATCAATGCTCCTACACGCTGCCCAATTCGATGCTGAGTCCGCTCCTGAGTCCGGaccaggcggcggcagccgTTGCGGCAGCTTCCGTGGCCAAtcatcagcaccagcaacagcagcagcatcagcatcatcagcacCAGAATCAACAGCAGAGACTCCAGCAGCAGATGAATGGCTATTCGGGGTCGACATCGCTGCCAGCGAGTCCCAGCCTGGGGGGAGCATCCATCAAAACAGAGGAATCCGAAGCCAAGACGTTAAGAGCGAGCAGTATTCCAACGCTATTGCAGGAAATCATGGATGTTGAACATCTTTGGCAGTACACCGATGCAGAGCTGGCCCGCATCAATCAGCCATTGTCCTCCTTTGCCTCTGTCGGCAGCTCCTCATCATCGTCGCCTGCCTCAGCGGCACACCAgaaccaccaacagcagcagcagcaacagcagcagcagcagcaattgacCAATCCACTGCTGGCCAGTGCCGGTCTCTCATCCAATGGGGAGAATGCCAATCCCGATCTGATTGCACACCTCTGCAATGTGGCCGATCATCGTCTCTACAAGATTGTCAAATGGTGCAAGAGTCTTCCACTTTTTAAGAACATTTCGATCGATGATCAAATCTGTTTGCTGATCAATTCCTGGTGCGAACTGCTGCTCTTCTCCTGCTGTTTTCGTTCGATTGATACGCCCGGCGAGATAAAGATGTCACAAGGCAGAAAGATAACACTATCACAGGCCAAAACGAATGGCCTTCAGACCTGCATCGAACGCATGCTCAATCTGACGGATCATTTGAGGCGCCTGCGCGTGGATCGCTACGAATATGTTGCCATGAAGGTGATAGTGCTGCTGCAGTCAGACACCACAGAGCTGCAGGAGGCGGTGAAAGTGCGGGAGTGCCAAGAGAAGGCATTGCAGGGCCTGCAGGCCTACACGCTGGCCCACTATCCGGATACGCCGTCCAAGTTTGGAGAGCTACTGCTGCGTATACCCGACCTGCAGCGCACATGTCAGCTGGGCAAAGAAATGCTCACGATCAAGACACGCGATGGAGCTGATTTCAATCTGCTGATGGAGCTGTTGCGCGGAGAACATTGA
Protein Sequence
MPNMSSIKAEQQSAPMGGTGSYQLPVNMCTTSSGSSNSTTMTMTTTGSATPSRHNVSVTNIKCELEELPTPNGNLVPVIANYNHGSLRIPLSGQPHNVEEESDSEAELTNIENLKVRRRAADKNGPRPMSWEGELSEPEENGGSGGGGGGGAELMETETVIKSEVCTTSTPIQAASTTCPTMQPIKTELDNIAGELQHHPRSNAYPVSSCNGPAKLKLAPTQSDPINLKYEPPLGDNNSPLLTTRNKSNSGGHLPLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHAPPAGSIYGNGVHHHGMLYRPLKVEAASSTSTGGSSQESAQNLSMDSASSAMDPLGSGSLPASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLLSPDQAAAAVAAASVANHQHQQQQQHQHHQHQNQQQRLQQQMNGYSGSTSLPASPSLGGASIKTEESEAKTLRASSIPTLLQEIMDVEHLWQYTDAELARINQPLSSFASVGSSSSSSPASAAHQNHQQQQQQQQQQQQLTNPLLASAGLSSNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSIDTPGEIKMSQGRKITLSQAKTNGLQTCIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTTELQEAVKVRECQEKALQGLQAYTLAHYPDTPSKFGELLLRIPDLQRTCQLGKEMLTIKTRDGADFNLLMELLRGEH