Dtrs000790.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila tristis
Gene Symbol
Hr39
Assembly
GCA_018150885.1
Location
JAECWT010000135.1:1048682-1052803[-]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 0.18 1.4e+03 -1.9 0.7 142 162 22 42 3 115 0.65
2 4 2 1.5e+04 -8.3 9.5 76 153 167 270 126 301 0.43
3 4 3e-10 2.3e-06 27.0 0.0 1 32 451 482 451 493 0.87
4 4 3e-84 2.3e-80 270.8 0.2 168 408 480 711 476 711 0.95

Sequence Information

Coding Sequence
ATGTCTAGCATTAAGGCTGAGCAGCAGAGTGCCCCAATGGGGGGCACGGGTAGCTATCAGCTGCCCGTGAATATGTGCACCAGCAGCAGCAGCAGCACCACGACGACGACGTCGACGCCATCGCGTCACAATGTGTCCGTGACGAATATTAAATGCGAACTGGAGGAGCTGCCCACGCCGAATGGCAACCTGGTGCCGGTCATCGCCAACTATAATCATGGCAGCCTGAGGATACCGCTCAGTGGGCAGCCGCACAACCAGCAGGAGGAGGAGGAGTCCGACTCCGAGGCGGAACTCACGAATATCGAGAACCTGAAGGTGCGCCGGCGAGCGGCGGATAAGAACGGGCCACGGCCCATGTCCTGGGAGGGAGAACTAAAGCTGATGGAAACGGAGACGGTGATCAAGAGTGAGCTGTGCACCACCACGTCCACGCCCATTCAGGCGGCGTCCACCACCTGCCCCACGATGCAACCGATCAAAACGGAGCTGGAGAACATTGCCGGAGAGCTGCAGCATCCGCGCAGCAACGCCTATCCGGTGTCCAGCTGCAATGGCCCCGCCAAACTGAAGCTGGCGCCCACCCAGAGCGATCCGATCAATCTCAAGTATGAGCCCCCGCTGGGGGACAACAACTCGCCGCTGCTGACGACGCGCAACAAGTCGAACAGCGGCGGACACCTGCCGCTGCCGGCGAATCCCAGTCCCGACTCTGCCATACATTCCGTCTACACCCACAGCTCACCGTCGCAGTCGCCGCTGACGTCGCGGCATGCCCCATACACGCCGTCGCTGAGTCGCAACAACAGCGATGCCTCGCACAGCAGCTGCTACAGCTACAGCTCGGAGTTTAGTCCGACACACTCGCCGATTCAGGCGCGGCATGCCCCACCAGCGGGCGCCATCTACGGGAATGGTGTGCATCATCACGGGATGCTGTACAGGCCGCTCAAGGTGGAGGCCTCCCCAACGGGCGGATCGGTTGGCGGTGGCGCTGGCGGTGGCGGTGGCTCTTGCAGCCAGGAGTCAGCACAAAATCTCAGCATGGACTCTGCCTCCAGTGGCTCCATGGATCCGCTGGGATCGGGCTCGCTGCCCGCCTCGCCGGCTGGCATCTCCCGCCAGCAGCTGATCAACTCCCCCTGCCCGATCTGCGGGGATAAGATCAGTGGCTTCCACTACGGCATCTTCTCCTGCGAGTCCTGCAAGGGTTTCTTCAAGCGCACCGTCCAGAATCGCAAGAACTATGTGTGCGTACGCGGCGGTCCCTGCCAGGTGAGCATTTCCACGCGCAAAAAATGCCCCGCCTGCCGGTTCGAGAAGTGCCTGCAAAAGGGCATGAAACTGGAGGCCATACGCGAGGATCGCACCCGTGGCGGTCGCTCCACCTACCAATGCTCCTACACGCTGCCCAATTCCATGCTGAGTCCGCTCTTAACGAGTCCCAGTCTGGGGGGAGCATCCATCAAAACGGAGGAAAACGAGTCCAAGACGCTAAGAGCGAGCAGTATTCCAACGCTATTGCAGGAAATCATGGATAACGCCAATCCCGATCTGATTGCACATCTCTGCAATGTGGCCGATCATCGCCTCTACAAGATTGTCAAATGGTGCAAGAGTCTTCCCCTTTTTAAGAACATTTCGATTGATGATCAAATTTGTCTGCTCATCAATTCGTGGTGCGAACTGCTGCTCTTCTCGTGCTGTTTTCGGTCGATTGATACGCCCGGCGAGATAAAGATGTCACAAGGCAGAAAGATAACACTATCACAGGCCAAAACGAATGGTCTTCAGACCTGCATCGAACGCATGCTCAATCTGACGGATCATTTGAGGCGCCTGCGCGTGGATCGCTACGAATATGTTGCCATGAAGGTGATAGTGCTGCTGCAGTCAGATACCACAGAGCTGCATGAGGCGGTGAAAGTGCGCGAGTGCCAGGAGAAGGCATTGCAGGGGCTGCAGGCCTACACGCTGGCCCACTATCCGGATACGCCCTCGAAGTTTGGGGAGCTGCTGCTGCGCATACCCGACCTGCAGCGCACCTGTCAGCTGGGCAAAGAAATGCTGACGATCAAGACACGCGATGGAGCTGATTTTAATCTGCTGATGGAGCTGTTGCGCGGAGAACATTGA
Protein Sequence
MSSIKAEQQSAPMGGTGSYQLPVNMCTSSSSSTTTTTSTPSRHNVSVTNIKCELEELPTPNGNLVPVIANYNHGSLRIPLSGQPHNQQEEEESDSEAELTNIENLKVRRRAADKNGPRPMSWEGELKLMETETVIKSELCTTTSTPIQAASTTCPTMQPIKTELENIAGELQHPRSNAYPVSSCNGPAKLKLAPTQSDPINLKYEPPLGDNNSPLLTTRNKSNSGGHLPLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHAPPAGAIYGNGVHHHGMLYRPLKVEASPTGGSVGGGAGGGGGSCSQESAQNLSMDSASSGSMDPLGSGSLPASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLLTSPSLGGASIKTEENESKTLRASSIPTLLQEIMDNANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSIDTPGEIKMSQGRKITLSQAKTNGLQTCIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTTELHEAVKVRECQEKALQGLQAYTLAHYPDTPSKFGELLLRIPDLQRTCQLGKEMLTIKTRDGADFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00484464;
90% Identity
iTF_00611399;
80% Identity
iTF_00611399;