Basic Information

Insect: Anopheles funestus
Gene Symbol: -
Assembly: None
Location: Contig0:3129721-3133382[-]

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 1.8 6.8e+03 -3.0 0.0 27 46 210 229 208 232 0.83

2 11 0.38 1.4e+03 -0.8 0.0 26 32 370 376 365 387 0.74

3 11 0.72 2.7e+03 -1.7 0.0 27 45 439 457 435 460 0.86

4 11 0.0041 15 5.5 0.0 21 45 461 485 455 489 0.89

5 11 0.00021 0.77 9.7 0.0 21 44 489 512 484 516 0.91

6 11 0.0039 14 5.6 0.1 21 45 517 541 513 546 0.89

7 11 0.13 5e+02 0.7 0.0 21 47 569 595 556 598 0.83

8 11 0.00015 0.56 10.1 0.1 21 52 598 629 588 630 0.82

9 11 0.025 92 3.0 0.0 22 45 655 678 652 685 0.84

10 11 0.0013 4.8 7.1 0.1 21 48 682 709 677 713 0.86

11 11 0.00025 0.93 9.4 0.0 21 45 710 734 708 740 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	1.8	6.8e+03	-3.0	0.0	27	46	210	229	208	232	0.83
2	11	0.38	1.4e+03	-0.8	0.0	26	32	370	376	365	387	0.74
3	11	0.72	2.7e+03	-1.7	0.0	27	45	439	457	435	460	0.86
4	11	0.0041	15	5.5	0.0	21	45	461	485	455	489	0.89
5	11	0.00021	0.77	9.7	0.0	21	44	489	512	484	516	0.91
6	11	0.0039	14	5.6	0.1	21	45	517	541	513	546	0.89
7	11	0.13	5e+02	0.7	0.0	21	47	569	595	556	598	0.83
8	11	0.00015	0.56	10.1	0.1	21	52	598	629	588	630	0.82
9	11	0.025	92	3.0	0.0	22	45	655	678	652	685	0.84
10	11	0.0013	4.8	7.1	0.1	21	48	682	709	677	713	0.86
11	11	0.00025	0.93	9.4	0.0	21	45	710	734	708	740	0.91

Sequence Information

Coding Sequence: ATGCTCGGCAAGTATGGCGAGGCGAGTTCCGGCTCGATGAAAAACCTGGATAATGGTCTGAGGGACCGGGTGCTGTACCATCAGAATATGCTGAGCATGAACCTGACGGCCGAATTTTACCACAATCCATTCCTAACGGCCGGTTCTGGTGGTGGTGGTGGTAGTAACGTCGGAGCAACGTCTGCAACCGGTACGCCCACGATGGCACAGTCGCAAAAGATGCTCAACAGTCTGGCATCCGCTAACCATCCGCAGCAACACGCCAGTAATGGATCGGCAACGGCAGCAGGTGTACCATCGCCGACAGTTCCAAGCAGTGCGTCCGCACAGCAATCGCTGACGCAGTACCAGTGTCAACTCTGTCAGAAGTGTTTCATTTCACCGGCTCTACTAACGCAACACATGAAAACACATGATAATAATGGATTCGTCGGTCGTGAAGCAACCAATTACGTCCAGCAGCAACAATCGGTAACATCGGCACCCTCACCCGTAACAGCCGTCGCATCAAGCAGTAAAACTAGTCCGCCACTGCTAACGCAGCACAACATTAAGAGCGAATATGTGGGTGGAACAGTATCGCACACGATGGGCCAGTTTGTGTACGGCATGGCGAAACAGTTCGAATGCCAAATTTGTCACAAATCCTTCATGACGATGGTGAACTTGAATCTGCACATGAAGATACACGAAGCGACCATAAAGCCGATTGCAGCGGCTCACATGTACTCGCAAGCGAGTGGCGGGAATTTGCTTGTCGGATCGACGGCTTCCGCAAGCTATCATAGCGGACAACATCACAATCAGCAGCATCATACAGTAGGCCCTGTGGTACCAAGCTCCAGTACCACCGCCGATGGAGTGTGTCAAATATGCCACAAAACTTTTAGCACGGCGGACCAGTTTGCGGCACATATGAAAATTCATGAAAACGAATTTAAAAACCGTGCACTGTACCATTCAAGCAGCGCGAATGCTAACGGAGATGCCGGTGGACCAGTATCGACCAGCAATGGTGGCGGTGTGGGGGATCATTTCTATGCTTCAGCGCCACCAACACACCAGCTGGTGCACGCCCCGCCACACCTCGACGCCAGCAAGGGCCACCGGTGTCCAATTTGTCACAAAATGTCCAACAACATCATTGAACATATTAAGCAACACGAAGGGCAGCTTACGATGGGTGGTGGCACTGGTGCGACAGGTGTCGTAGGATCGTCGCCCGGACCAGGCGGCTTTCAACAAACGAACGAAGATTCACAATCCTCGCTGGAAGACGATAGTGATGGTGGCGAGAACGTCCGAAAGCACGAGTGCTTGATCTGCCATAAGAAGTTTTCCAGCTCGGGCAATCTGGCCATTCACATACGGGTACACTCGGGTGAGAAACCGTTCAAGTGCAGCGTGTGCGGCAAGGGCTTCATCCAGTCGAACAATCTGGCGACGCACATGAAGACACACACGGGCGAAAAACCGTACGCGTGTACCATCTGCGGGAAAAACTTTAGTCAGTCAAACAACCTGAAAACACACATCCGGACGCACACCGGTGAAAAACCGTACGCGTGCACCATCTGCGGCAAGCGGTTTAATCAGAAAAACAATCTGACCACGCACATGCGCACGCATCAGCTCGTGTGCATGGTGTGCGGCGTGCAGTTCATGCATCCGTCCGATCTGGCGAACCACATGAAGTTCCACAACGATGAAAAGCCGTTCATTTGCTCGGTGTGCAACAAGGTTTACCTGAACTTGGACGAGCTGACCGAGCACATGAAGAAGACGCACAACCAAGTGAAACCGTACCGGTGCCACATCTGCGACAAGACGTTCACGCAGTCAAACAATCTGAAAACCCACATCAAGACGCACATCTTTCAGGATCCGTACAAGTGTCAGATGTGTTCCCGTTCGTTCCAGAAGGAGGACGACTACTCGCAGCACATGCTGGTGCATACGGCGGACAAGCCGTACGAGTGCACGTACTGCGGCAAGCGGTTCATACAATCGAACAATTTGAAAACCCACGTCCGAACGCACACGGGCGAAAAGCCTTACCGGTGTACGATCTGTGCGAAAAACTTCAACCAGAAGAACAATCTCAATACGCACATGCGCATCCACACGGGCGAGAAACCGTTTGAATGTACGATCTGTGACAAGCGGTTCAATCAGTCGAACAACCTGAACAAGCACATCAAAACGCACGGACAGGAAAAGGACCAGCAGCAGCAGCAGCAAGCGAGTTGA
Protein Sequence: MLGKYGEASSGSMKNLDNGLRDRVLYHQNMLSMNLTAEFYHNPFLTAGSGGGGGSNVGATSATGTPTMAQSQKMLNSLASANHPQQHASNGSATAAGVPSPTVPSSASAQQSLTQYQCQLCQKCFISPALLTQHMKTHDNNGFVGREATNYVQQQQSVTSAPSPVTAVASSSKTSPPLLTQHNIKSEYVGGTVSHTMGQFVYGMAKQFECQICHKSFMTMVNLNLHMKIHEATIKPIAAAHMYSQASGGNLLVGSTASASYHSGQHHNQQHHTVGPVVPSSSTTADGVCQICHKTFSTADQFAAHMKIHENEFKNRALYHSSSANANGDAGGPVSTSNGGGVGDHFYASAPPTHQLVHAPPHLDASKGHRCPICHKMSNNIIEHIKQHEGQLTMGGGTGATGVVGSSPGPGGFQQTNEDSQSSLEDDSDGGENVRKHECLICHKKFSSSGNLAIHIRVHSGEKPFKCSVCGKGFIQSNNLATHMKTHTGEKPYACTICGKNFSQSNNLKTHIRTHTGEKPYACTICGKRFNQKNNLTTHMRTHQLVCMVCGVQFMHPSDLANHMKFHNDEKPFICSVCNKVYLNLDELTEHMKKTHNQVKPYRCHICDKTFTQSNNLKTHIKTHIFQDPYKCQMCSRSFQKEDDYSQHMLVHTADKPYECTYCGKRFIQSNNLKTHVRTHTGEKPYRCTICAKNFNQKNNLNTHMRIHTGEKPFECTICDKRFNQSNNLNKHIKTHGQEKDQQQQQQAS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00101809; iTF_00105516; iTF_00105275; iTF_00105279; iTF_00108535; iTF_00108809; iTF_00098171; iTF_00097912;
90% Identity: iTF_00098171;
80% Identity: iTF_00101809;