Afun012742.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles funestus
Gene Symbol
-
Assembly
None
Location
Contig0:3129721-3133382[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 4.6e-07 2.8e-05 24.1 2.3 1 23 116 138 116 138 0.99
2 15 3.9e-06 0.00024 21.1 1.9 1 23 208 230 208 230 0.98
3 15 7e-07 4.2e-05 23.5 0.9 2 23 288 309 288 309 0.97
4 15 0.51 31 5.0 0.7 1 10 369 378 369 388 0.79
5 15 9.2e-07 5.6e-05 23.1 1.7 1 23 437 459 437 459 0.98
6 15 4.9e-08 2.9e-06 27.1 0.6 1 23 465 487 465 487 0.99
7 15 9e-09 5.4e-07 29.4 1.0 1 23 493 515 493 515 0.98
8 15 6.2e-09 3.7e-07 29.9 1.8 1 23 521 543 521 543 0.98
9 15 0.00023 0.014 15.5 0.3 2 23 546 567 545 567 0.95
10 15 0.00032 0.019 15.1 0.4 1 23 573 596 573 596 0.97
11 15 2e-08 1.2e-06 28.3 4.7 1 23 602 624 602 624 0.99
12 15 0.00017 0.01 16.0 1.4 1 23 630 652 630 652 0.99
13 15 2.8e-08 1.7e-06 27.9 1.8 1 23 658 680 658 680 0.99
14 15 3.1e-07 1.8e-05 24.6 1.7 1 23 686 708 686 708 0.99
15 15 2.5e-08 1.5e-06 28.0 2.0 1 23 714 736 714 736 0.98

Sequence Information

Coding Sequence
ATGCTCGGCAAGTATGGCGAGGCGAGTTCCGGCTCGATGAAAAACCTGGATAATGGTCTGAGGGACCGGGTGCTGTACCATCAGAATATGCTGAGCATGAACCTGACGGCCGAATTTTACCACAATCCATTCCTAACGGCCGGTTCTGGTGGTGGTGGTGGTAGTAACGTCGGAGCAACGTCTGCAACCGGTACGCCCACGATGGCACAGTCGCAAAAGATGCTCAACAGTCTGGCATCCGCTAACCATCCGCAGCAACACGCCAGTAATGGATCGGCAACGGCAGCAGGTGTACCATCGCCGACAGTTCCAAGCAGTGCGTCCGCACAGCAATCGCTGACGCAGTACCAGTGTCAACTCTGTCAGAAGTGTTTCATTTCACCGGCTCTACTAACGCAACACATGAAAACACATGATAATAATGGATTCGTCGGTCGTGAAGCAACCAATTACGTCCAGCAGCAACAATCGGTAACATCGGCACCCTCACCCGTAACAGCCGTCGCATCAAGCAGTAAAACTAGTCCGCCACTGCTAACGCAGCACAACATTAAGAGCGAATATGTGGGTGGAACAGTATCGCACACGATGGGCCAGTTTGTGTACGGCATGGCGAAACAGTTCGAATGCCAAATTTGTCACAAATCCTTCATGACGATGGTGAACTTGAATCTGCACATGAAGATACACGAAGCGACCATAAAGCCGATTGCAGCGGCTCACATGTACTCGCAAGCGAGTGGCGGGAATTTGCTTGTCGGATCGACGGCTTCCGCAAGCTATCATAGCGGACAACATCACAATCAGCAGCATCATACAGTAGGCCCTGTGGTACCAAGCTCCAGTACCACCGCCGATGGAGTGTGTCAAATATGCCACAAAACTTTTAGCACGGCGGACCAGTTTGCGGCACATATGAAAATTCATGAAAACGAATTTAAAAACCGTGCACTGTACCATTCAAGCAGCGCGAATGCTAACGGAGATGCCGGTGGACCAGTATCGACCAGCAATGGTGGCGGTGTGGGGGATCATTTCTATGCTTCAGCGCCACCAACACACCAGCTGGTGCACGCCCCGCCACACCTCGACGCCAGCAAGGGCCACCGGTGTCCAATTTGTCACAAAATGTCCAACAACATCATTGAACATATTAAGCAACACGAAGGGCAGCTTACGATGGGTGGTGGCACTGGTGCGACAGGTGTCGTAGGATCGTCGCCCGGACCAGGCGGCTTTCAACAAACGAACGAAGATTCACAATCCTCGCTGGAAGACGATAGTGATGGTGGCGAGAACGTCCGAAAGCACGAGTGCTTGATCTGCCATAAGAAGTTTTCCAGCTCGGGCAATCTGGCCATTCACATACGGGTACACTCGGGTGAGAAACCGTTCAAGTGCAGCGTGTGCGGCAAGGGCTTCATCCAGTCGAACAATCTGGCGACGCACATGAAGACACACACGGGCGAAAAACCGTACGCGTGTACCATCTGCGGGAAAAACTTTAGTCAGTCAAACAACCTGAAAACACACATCCGGACGCACACCGGTGAAAAACCGTACGCGTGCACCATCTGCGGCAAGCGGTTTAATCAGAAAAACAATCTGACCACGCACATGCGCACGCATCAGCTCGTGTGCATGGTGTGCGGCGTGCAGTTCATGCATCCGTCCGATCTGGCGAACCACATGAAGTTCCACAACGATGAAAAGCCGTTCATTTGCTCGGTGTGCAACAAGGTTTACCTGAACTTGGACGAGCTGACCGAGCACATGAAGAAGACGCACAACCAAGTGAAACCGTACCGGTGCCACATCTGCGACAAGACGTTCACGCAGTCAAACAATCTGAAAACCCACATCAAGACGCACATCTTTCAGGATCCGTACAAGTGTCAGATGTGTTCCCGTTCGTTCCAGAAGGAGGACGACTACTCGCAGCACATGCTGGTGCATACGGCGGACAAGCCGTACGAGTGCACGTACTGCGGCAAGCGGTTCATACAATCGAACAATTTGAAAACCCACGTCCGAACGCACACGGGCGAAAAGCCTTACCGGTGTACGATCTGTGCGAAAAACTTCAACCAGAAGAACAATCTCAATACGCACATGCGCATCCACACGGGCGAGAAACCGTTTGAATGTACGATCTGTGACAAGCGGTTCAATCAGTCGAACAACCTGAACAAGCACATCAAAACGCACGGACAGGAAAAGGACCAGCAGCAGCAGCAGCAAGCGAGTTGA
Protein Sequence
MLGKYGEASSGSMKNLDNGLRDRVLYHQNMLSMNLTAEFYHNPFLTAGSGGGGGSNVGATSATGTPTMAQSQKMLNSLASANHPQQHASNGSATAAGVPSPTVPSSASAQQSLTQYQCQLCQKCFISPALLTQHMKTHDNNGFVGREATNYVQQQQSVTSAPSPVTAVASSSKTSPPLLTQHNIKSEYVGGTVSHTMGQFVYGMAKQFECQICHKSFMTMVNLNLHMKIHEATIKPIAAAHMYSQASGGNLLVGSTASASYHSGQHHNQQHHTVGPVVPSSSTTADGVCQICHKTFSTADQFAAHMKIHENEFKNRALYHSSSANANGDAGGPVSTSNGGGVGDHFYASAPPTHQLVHAPPHLDASKGHRCPICHKMSNNIIEHIKQHEGQLTMGGGTGATGVVGSSPGPGGFQQTNEDSQSSLEDDSDGGENVRKHECLICHKKFSSSGNLAIHIRVHSGEKPFKCSVCGKGFIQSNNLATHMKTHTGEKPYACTICGKNFSQSNNLKTHIRTHTGEKPYACTICGKRFNQKNNLTTHMRTHQLVCMVCGVQFMHPSDLANHMKFHNDEKPFICSVCNKVYLNLDELTEHMKKTHNQVKPYRCHICDKTFTQSNNLKTHIKTHIFQDPYKCQMCSRSFQKEDDYSQHMLVHTADKPYECTYCGKRFIQSNNLKTHVRTHTGEKPYRCTICAKNFNQKNNLNTHMRIHTGEKPFECTICDKRFNQSNNLNKHIKTHGQEKDQQQQQQAS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00102066;
90% Identity
iTF_00098171;
80% Identity
iTF_00102066;