Basic Information

Insect: Anopheles stephensi
Gene Symbol: -
Assembly: GCA_013141755.1
Location: CM023249.1:2861055-2864751[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 6.7e-05 0.0039 17.4 2.0 1 23 101 123 101 123 0.99

2 14 4.1e-06 0.00023 21.2 1.9 1 23 196 218 196 218 0.98

3 14 1e-06 5.8e-05 23.1 0.8 3 23 286 306 285 306 0.98

4 14 9.4e-07 5.4e-05 23.2 1.7 1 23 399 421 399 421 0.98

5 14 5e-08 2.9e-06 27.2 0.6 1 23 427 449 427 449 0.99

6 14 9.2e-09 5.3e-07 29.5 1.0 1 23 455 477 455 477 0.98

7 14 6.3e-09 3.7e-07 30.0 1.8 1 23 483 505 483 505 0.98

8 14 0.00024 0.014 15.6 0.3 2 23 508 529 507 529 0.95

9 14 0.00033 0.019 15.2 0.4 1 23 535 558 535 558 0.97

10 14 2e-08 1.2e-06 28.4 4.7 1 23 564 586 564 586 0.99

11 14 0.00018 0.01 16.0 1.4 1 23 592 614 592 614 0.99

12 14 2.8e-08 1.6e-06 28.0 1.8 1 23 620 642 620 642 0.99

13 14 9.8e-07 5.6e-05 23.1 3.6 1 23 648 670 648 670 0.99

14 14 2.6e-08 1.5e-06 28.1 2.0 1 23 676 698 676 698 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	6.7e-05	0.0039	17.4	2.0	1	23	101	123	101	123	0.99
2	14	4.1e-06	0.00023	21.2	1.9	1	23	196	218	196	218	0.98
3	14	1e-06	5.8e-05	23.1	0.8	3	23	286	306	285	306	0.98
4	14	9.4e-07	5.4e-05	23.2	1.7	1	23	399	421	399	421	0.98
5	14	5e-08	2.9e-06	27.2	0.6	1	23	427	449	427	449	0.99
6	14	9.2e-09	5.3e-07	29.5	1.0	1	23	455	477	455	477	0.98
7	14	6.3e-09	3.7e-07	30.0	1.8	1	23	483	505	483	505	0.98
8	14	0.00024	0.014	15.6	0.3	2	23	508	529	507	529	0.95
9	14	0.00033	0.019	15.2	0.4	1	23	535	558	535	558	0.97
10	14	2e-08	1.2e-06	28.4	4.7	1	23	564	586	564	586	0.99
11	14	0.00018	0.01	16.0	1.4	1	23	592	614	592	614	0.99
12	14	2.8e-08	1.6e-06	28.0	1.8	1	23	620	642	620	642	0.99
13	14	9.8e-07	5.6e-05	23.1	3.6	1	23	648	670	648	670	0.99
14	14	2.6e-08	1.5e-06	28.1	2.0	1	23	676	698	676	698	0.98

Sequence Information

Coding Sequence: ATGCTCGGCAAGTATGGCGAGACGAGTTCCGGCTCGATGAAAAACCTGGATAATGGGCTGCGGGACCGGGTGCTGTACCATCAGAACATGCTGAGCATGAACCTGACGGCCGAATTTTACCACAATCCATTCCTTGCGGCTGGGGCTGGTAGTAACGGTGGAACGACCGCAAGCGGAACCCCCACGATGGCACAGTCGCAAAAGATGCTCAACAGTCTGGCAACATCGCCACAGCAGCACACCAGCAATGGATCAGCAACAGTTCCAAACAGTGCGTCCTCGCAGCAATCCCTCACACAATACCAGTGTCAGCTTTGTCAGAAGTGTTTCATCTCAAGCGCAATTCTAGCGCAGCACATGAAAACACACGACAGCAATGGATTCGGCGCTCGGGAAGCAGGCAATTAcgtccaacagcagcagcaatcggtAACATCTTCGACACCGTCGTCCGTACCGGCAGCGGTAGCATCAAGCAGTAAAACTAGTCCACCACTGCTGACCCAGCACAACATCAAGAGCGAGTATGTCGGCGGAACGGTGATCAACACGATGGGCCCATTCGTGTACGGCATGGCCAAGCAGTTCGAATGCCAAATCTGTCACAAATCCTTCATGACGATGGTGAACCTGAACCTGCACATGAAAATACACGAAGCTGTGCTAAAACCGATCACAGCAGCCCATATGTATTCACCATCGAGCGGGAGCAACTTGGTTGCCGGGACAACAGCGTCATCATCTGCAAGCTATCTCACCGGCCACAACCAtcacaaccagcagcagcagcaacagcagcagcatcacacgATAGTCCCTTCCGTGCATAGTCCCAGTGGTAGCACCGACGGAGCGTGTCAAATATGTCACAAAACGTTTAGCACCGCGGACCAGTTTGCGGCGCACATGAAAATCCATGAGAATGAGTTTAAAAATCGTGCCCTTTACCATTCAAGCAGCTCGGCGAACGCCAACAACGGTGCGGATGATGGGTCCACCAGCAATGGGGATCATTTCTACGCCTCGTTGCCACCCACACACCAGCAAGTGcacggaccaccaccaccaccaccaccaccgcatcTCGACGCGAGCAAGGGCCACCGGTCCGGCGGTTATCAGCAACCGAACGACGATTCACAATCATCGCTCGAGGACGATagtgacggtggtggtgagaATGGGCACCGGAAGCACGAGTGTTTGATCTGCCACAAAAAGTTTTCCAGCTCCGGCAATCTGGCCATCCACATACGGGTCCATTCGGGCGAGAAGCCATTCAAGTGCAGCGTGTGCGGCAAGGGCTTCATCCAGTCGAACAATTTGGCCACCCACATGAAAACGCACACGGGCGAAAAGCCGTACGCTTGCACGATCTGTGGTAAAAACTTTAGCCAGTCCAACAATCTGAAAACGCACATCCGGACGCACACGGGCGAAAAGCCGTACGCGTGCACGATCTGCGGGAAGCGGTTCAATCAGAAGAACAACCTCACCACGCACATGCGAACGCACCAGCTCGTCTGTATGGTGTGCGGTGTGCAGTTTATGCATCCGTCCGATCTGGCGAACCACATGAAGTTCCACAACGACGAAAAGCCGTTCATCTGCTCGGTGTGCAACAAGGTGTACCTGAACCTGGACGAGCTGACCGAGCATATGAAGAAGACGCACAACCAGGTGAAACCGTACCGGTGCCACATATGCGACAAAACGTTCACGCAATCGAACAACCTGAAGACGCACATCAAGACACACATCTTTCAGGATCCGTACAAGTGCCAGATGTGCTCGCGGTCGTTCCAGAAGGAGGACGACTATTCGCAGCACATGCTGGTGCACACGGCGGACAAACCGTACGAGTGTACGTACTGCGGCAAGCGGTTCATCCAGTCGAACAATCTGAAAACGCACGTCCGGACGCACACGGGCGAAAAGCCGTACCGGTGTACGATCTGTGCGAAGCACTTTAACCAGAAGAACAATCTCAACACGCACATGCGCATCCACACGGGGGAAAAGCCGTTCGAGTGTACGATCTGCGACAAGCGGTTCAACCAGTCGAACAATCTGAACAAGCACATCAAAACGCACGGTCAGGAaaaggaccagcagcagcagcagcagcagcaagcgagTTGA
Protein Sequence: MLGKYGETSSGSMKNLDNGLRDRVLYHQNMLSMNLTAEFYHNPFLAAGAGSNGGTTASGTPTMAQSQKMLNSLATSPQQHTSNGSATVPNSASSQQSLTQYQCQLCQKCFISSAILAQHMKTHDSNGFGAREAGNYVQQQQQSVTSSTPSSVPAAVASSSKTSPPLLTQHNIKSEYVGGTVINTMGPFVYGMAKQFECQICHKSFMTMVNLNLHMKIHEAVLKPITAAHMYSPSSGSNLVAGTTASSSASYLTGHNHHNQQQQQQQQHHTIVPSVHSPSGSTDGACQICHKTFSTADQFAAHMKIHENEFKNRALYHSSSSANANNGADDGSTSNGDHFYASLPPTHQQVHGPPPPPPPPHLDASKGHRSGGYQQPNDDSQSSLEDDSDGGGENGHRKHECLICHKKFSSSGNLAIHIRVHSGEKPFKCSVCGKGFIQSNNLATHMKTHTGEKPYACTICGKNFSQSNNLKTHIRTHTGEKPYACTICGKRFNQKNNLTTHMRTHQLVCMVCGVQFMHPSDLANHMKFHNDEKPFICSVCNKVYLNLDELTEHMKKTHNQVKPYRCHICDKTFTQSNNLKTHIKTHIFQDPYKCQMCSRSFQKEDDYSQHMLVHTADKPYECTYCGKRFIQSNNLKTHVRTHTGEKPYRCTICAKHFNQKNNLNTHMRIHTGEKPFECTICDKRFNQSNNLNKHIKTHGQEKDQQQQQQQQAS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00102066;
90% Identity: iTF_00108809;
80% Identity: iTF_00108809;