Basic Information

Insect: Anopheles stephensi
Gene Symbol: -
Assembly: GCA_013141755.1
Location: CM023249.1:2861055-2864751[-]

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 2.4 1.2e+04 -3.7 0.6 19 43 95 119 89 122 0.60

2 11 1.2 6.2e+03 -2.8 0.0 27 46 198 217 195 220 0.83

3 11 0.28 1.4e+03 -0.7 0.0 27 47 401 421 397 426 0.83

4 11 0.003 15 5.5 0.0 21 45 423 447 417 450 0.89

5 11 0.00011 0.54 10.2 0.0 21 45 451 475 448 482 0.87

6 11 0.0027 14 5.7 0.1 21 45 479 503 474 508 0.89

7 11 0.095 4.8e+02 0.7 0.0 21 47 531 557 518 560 0.83

8 11 0.00011 0.54 10.2 0.1 21 52 560 591 550 592 0.82

9 11 0.018 90 3.1 0.0 22 45 617 640 614 647 0.84

10 11 0.001 5.2 7.1 0.2 21 48 644 671 640 675 0.86

11 11 0.00018 0.91 9.5 0.0 21 45 672 696 670 702 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	2.4	1.2e+04	-3.7	0.6	19	43	95	119	89	122	0.60
2	11	1.2	6.2e+03	-2.8	0.0	27	46	198	217	195	220	0.83
3	11	0.28	1.4e+03	-0.7	0.0	27	47	401	421	397	426	0.83
4	11	0.003	15	5.5	0.0	21	45	423	447	417	450	0.89
5	11	0.00011	0.54	10.2	0.0	21	45	451	475	448	482	0.87
6	11	0.0027	14	5.7	0.1	21	45	479	503	474	508	0.89
7	11	0.095	4.8e+02	0.7	0.0	21	47	531	557	518	560	0.83
8	11	0.00011	0.54	10.2	0.1	21	52	560	591	550	592	0.82
9	11	0.018	90	3.1	0.0	22	45	617	640	614	647	0.84
10	11	0.001	5.2	7.1	0.2	21	48	644	671	640	675	0.86
11	11	0.00018	0.91	9.5	0.0	21	45	672	696	670	702	0.91

Sequence Information

Coding Sequence: ATGCTCGGCAAGTATGGCGAGACGAGTTCCGGCTCGATGAAAAACCTGGATAATGGGCTGCGGGACCGGGTGCTGTACCATCAGAACATGCTGAGCATGAACCTGACGGCCGAATTTTACCACAATCCATTCCTTGCGGCTGGGGCTGGTAGTAACGGTGGAACGACCGCAAGCGGAACCCCCACGATGGCACAGTCGCAAAAGATGCTCAACAGTCTGGCAACATCGCCACAGCAGCACACCAGCAATGGATCAGCAACAGTTCCAAACAGTGCGTCCTCGCAGCAATCCCTCACACAATACCAGTGTCAGCTTTGTCAGAAGTGTTTCATCTCAAGCGCAATTCTAGCGCAGCACATGAAAACACACGACAGCAATGGATTCGGCGCTCGGGAAGCAGGCAATTAcgtccaacagcagcagcaatcggtAACATCTTCGACACCGTCGTCCGTACCGGCAGCGGTAGCATCAAGCAGTAAAACTAGTCCACCACTGCTGACCCAGCACAACATCAAGAGCGAGTATGTCGGCGGAACGGTGATCAACACGATGGGCCCATTCGTGTACGGCATGGCCAAGCAGTTCGAATGCCAAATCTGTCACAAATCCTTCATGACGATGGTGAACCTGAACCTGCACATGAAAATACACGAAGCTGTGCTAAAACCGATCACAGCAGCCCATATGTATTCACCATCGAGCGGGAGCAACTTGGTTGCCGGGACAACAGCGTCATCATCTGCAAGCTATCTCACCGGCCACAACCAtcacaaccagcagcagcagcaacagcagcagcatcacacgATAGTCCCTTCCGTGCATAGTCCCAGTGGTAGCACCGACGGAGCGTGTCAAATATGTCACAAAACGTTTAGCACCGCGGACCAGTTTGCGGCGCACATGAAAATCCATGAGAATGAGTTTAAAAATCGTGCCCTTTACCATTCAAGCAGCTCGGCGAACGCCAACAACGGTGCGGATGATGGGTCCACCAGCAATGGGGATCATTTCTACGCCTCGTTGCCACCCACACACCAGCAAGTGcacggaccaccaccaccaccaccaccaccgcatcTCGACGCGAGCAAGGGCCACCGGTCCGGCGGTTATCAGCAACCGAACGACGATTCACAATCATCGCTCGAGGACGATagtgacggtggtggtgagaATGGGCACCGGAAGCACGAGTGTTTGATCTGCCACAAAAAGTTTTCCAGCTCCGGCAATCTGGCCATCCACATACGGGTCCATTCGGGCGAGAAGCCATTCAAGTGCAGCGTGTGCGGCAAGGGCTTCATCCAGTCGAACAATTTGGCCACCCACATGAAAACGCACACGGGCGAAAAGCCGTACGCTTGCACGATCTGTGGTAAAAACTTTAGCCAGTCCAACAATCTGAAAACGCACATCCGGACGCACACGGGCGAAAAGCCGTACGCGTGCACGATCTGCGGGAAGCGGTTCAATCAGAAGAACAACCTCACCACGCACATGCGAACGCACCAGCTCGTCTGTATGGTGTGCGGTGTGCAGTTTATGCATCCGTCCGATCTGGCGAACCACATGAAGTTCCACAACGACGAAAAGCCGTTCATCTGCTCGGTGTGCAACAAGGTGTACCTGAACCTGGACGAGCTGACCGAGCATATGAAGAAGACGCACAACCAGGTGAAACCGTACCGGTGCCACATATGCGACAAAACGTTCACGCAATCGAACAACCTGAAGACGCACATCAAGACACACATCTTTCAGGATCCGTACAAGTGCCAGATGTGCTCGCGGTCGTTCCAGAAGGAGGACGACTATTCGCAGCACATGCTGGTGCACACGGCGGACAAACCGTACGAGTGTACGTACTGCGGCAAGCGGTTCATCCAGTCGAACAATCTGAAAACGCACGTCCGGACGCACACGGGCGAAAAGCCGTACCGGTGTACGATCTGTGCGAAGCACTTTAACCAGAAGAACAATCTCAACACGCACATGCGCATCCACACGGGGGAAAAGCCGTTCGAGTGTACGATCTGCGACAAGCGGTTCAACCAGTCGAACAATCTGAACAAGCACATCAAAACGCACGGTCAGGAaaaggaccagcagcagcagcagcagcagcaagcgagTTGA
Protein Sequence: MLGKYGETSSGSMKNLDNGLRDRVLYHQNMLSMNLTAEFYHNPFLAAGAGSNGGTTASGTPTMAQSQKMLNSLATSPQQHTSNGSATVPNSASSQQSLTQYQCQLCQKCFISSAILAQHMKTHDSNGFGAREAGNYVQQQQQSVTSSTPSSVPAAVASSSKTSPPLLTQHNIKSEYVGGTVINTMGPFVYGMAKQFECQICHKSFMTMVNLNLHMKIHEAVLKPITAAHMYSPSSGSNLVAGTTASSSASYLTGHNHHNQQQQQQQQHHTIVPSVHSPSGSTDGACQICHKTFSTADQFAAHMKIHENEFKNRALYHSSSSANANNGADDGSTSNGDHFYASLPPTHQQVHGPPPPPPPPHLDASKGHRSGGYQQPNDDSQSSLEDDSDGGGENGHRKHECLICHKKFSSSGNLAIHIRVHSGEKPFKCSVCGKGFIQSNNLATHMKTHTGEKPYACTICGKNFSQSNNLKTHIRTHTGEKPYACTICGKRFNQKNNLTTHMRTHQLVCMVCGVQFMHPSDLANHMKFHNDEKPFICSVCNKVYLNLDELTEHMKKTHNQVKPYRCHICDKTFTQSNNLKTHIKTHIFQDPYKCQMCSRSFQKEDDYSQHMLVHTADKPYECTYCGKRFIQSNNLKTHVRTHTGEKPYRCTICAKHFNQKNNLNTHMRIHTGEKPFECTICDKRFNQSNNLNKHIKTHGQEKDQQQQQQQQAS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00102066;
90% Identity: iTF_00108535;
80% Identity: iTF_00108535;