Adis033571.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anastatus disparis
Gene Symbol
Hr39
Assembly
GCA_017163975.1
Location
JAFFSR010000221.1:8754137-8762816[+]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 3 1.1e+05 -6.5 10.9 51 147 182 276 115 304 0.55
2 3 0.7 2.7e+04 -3.2 3.6 72 132 292 362 276 378 0.50
3 3 7.3e-80 2.8e-75 256.9 1.3 1 408 470 861 470 861 0.79

Sequence Information

Coding Sequence
ATGGCAAGTGGCAAACATGGTAAAAGCATATGCAAATATCTTGGCGGTCAAAATGGTGTTACAGTATCAGTAGTATCAAGTTGTGGTAGTACGCAAAATGCAAGCAATTCAAATGTAACACAAGTAGTGGATTCAGGATCGAATGAATCAGCTGCAAATGTTTCAGTTGATGATGCTGATGGTGATAGTGATGGTGAAGTAAGTCGTATAGATTTTCGTGGCGTTAACTTAAGaactaaaaagaaaagagaTGGTAGTATAGGACCTCacgataataatgaaaattcatgTGATGCTATTTATCAACAACCTGAAAGACCAATGTCTTGGGAAGGTGAATTATCTGATCAGGAAATGTCTTCCAATACTATTACAAATCagGATCATGAAGAAACATCGATGGAAGGTGTTCAAATATGCAGTTCGAGTCCTGGTCCACAAGAACAAAAGTTTCCAATTAAACCTGAACCAGATTTTCGCTCAAGTCCTGGGCTTCAAAGCCTTGGCAGTTCACTTAATGAAACTATTGTTGCTGTTCCACATGTTCAACAATTGCATCATCAGCATCAACAAGcgcaacaacagcagcaacaaaATATCGAGCAAAATCAACAAAGTGATTTACCGTTACTCGTTGGCAAATTACTTGGCGGTTGTAATAGTTCAACGCCGAATCATAGTCCTGTACTCATTCCTCGGCATCATTTGACCAAACACAGCCACACTAGATCTCAAgTCCCATCACCAGATTCAGCGATCCATTCGGCGTACAGCGTATTTAGTTCGCCAACTCAATCACCACATGCTGGTCGTCATTCAGCTCTTGGTCCAGGTTCACCAGTACCATCGTCTTCACTTTCACTTTCGCGACATAGTTTTAACAATTCAACCTCATCATTATCACTATCTTTGTCACACTCATTATCGCGTAATAATTCAGATGCCTCAAGCAGTTGTTATAGTTATGGTTCTCTTAGTCCACCTACGCATTCGCCAGTTCAACAGCGTTATGCTCATCATCATCAACAGCAACATCAAGTTCAATCAAATCCATTACATTTACAACAAGGGCATCATTATAGTGGAACTACAGGTGTTGTTAATGATGTAAGTGAAACACATTTGGATGATCAAGATGATTGTAGAATACCTTCTGCACCATCGGGCATATCGACAAGGCAACAATTAATTAACAGTCCTTGTCCGATTTGTGGAGACAAAATTAGCGGATTTCATTATGGAATATTTTCATGTGAATCCTGTAAGgGCTTCTTTAAAAGGACAGTgcaaaatcgaaaaaattacGTGTGTCTTAGAGGTGCAGGTTGTCCGGTAACAGTGGCTACGCGCAAAAAATGTCCTGCTTGTCGCTTTGATAAATGCCTAAATATGGGTATGAAACTCGAAGCGATAAGAGAAGATAGAACTCGTGGTGGTCGTAGCACATATCAGTGCACTTATACTTTACCTGCAAATCTATTAGGTGGTTCATCTGCACAAGGCGGCTTACCTGGTCAAGATAAAATGAGTCAAGGTCCATGCAGTCCAGCGCCGCCAGGTTCCGAACATCATCATTCAATGAAACATCATCATTCTAATCATTCCCATAAAATGCAATTAGTACCACAGTTACTTCAAGATATTATGGATGTAGAACATCTTTGGCATTATAATGACAATGATAGAGTTGGAGCCAGTCAGGCAATGGGTTCGCTCAATCTTGCTCagTCCTTACCCAATTCCGGAATGGATAATTCTCCAAGTGGTAATAGTAGTAGCGGAGACTCATTGAGTGGTTTAGGTACATCAAATGGTCTCACTAGCAGTTCCAGCGCAACTAACAATGGCAATTTAAATTCTCGCTCAGATTTATCACGCCTGACCTCTTCCAATTCATCGACGCCCACTCCAATACATGAACAGCAACATTCTCCATCATCTAACAGTGCGGCAAGCTCAAGTAACTCGGCAAATGGCAATCCAACACAACATCCTGATTTCTtatcaaatttatgtaatatagcTGACCACCGActatataaaattgttaaatggTGCAAAAGCTTaccactttttaaaaatatatccatTGACGATCAAATATGTTTGCTCATCAATTCATGGTGCGAACTACTACTTTTTTCGTGCTGTTTTCGAAGCATGAGTACACCTGGAGAGATCAGAGTTTCATTAGGAAAAAGTATTACATTAGAACAGGCCAAACAGTTGGGTTTAGCTACTTGCATTGAAAGAATGTTAGCGTTTACTAATAATCTTAGGCGTCTCAGAGTCGATCAATATGAATATGTTGCCATGaagGTGATTGTGCTGTTAACATCTGACACGAGCGAATTGAAAGAACCAGAAAAGGTTCGCGCATCTCAAGAGAAGGCATTGCAAGCATTACAGCAATACACAATCGCAAGGTATCCGGAAATGCCTGCCAAATTTGGTGAATTGCTACTTAGAATTCCTGATCTTCAACGTACTTGCCAAGCAGGCAAAGAGCTATTAAGCGCTAAACGCGCTGAAGGTGAAGGTTGCTCTTTTAATTTACTCATGGAGCTACTTCGAGGGGACCATTAG
Protein Sequence
MASGKHGKSICKYLGGQNGVTVSVVSSCGSTQNASNSNVTQVVDSGSNESAANVSVDDADGDSDGEVSRIDFRGVNLRTKKKRDGSIGPHDNNENSCDAIYQQPERPMSWEGELSDQEMSSNTITNQDHEETSMEGVQICSSSPGPQEQKFPIKPEPDFRSSPGLQSLGSSLNETIVAVPHVQQLHHQHQQAQQQQQQNIEQNQQSDLPLLVGKLLGGCNSSTPNHSPVLIPRHHLTKHSHTRSQVPSPDSAIHSAYSVFSSPTQSPHAGRHSALGPGSPVPSSSLSLSRHSFNNSTSSLSLSLSHSLSRNNSDASSSCYSYGSLSPPTHSPVQQRYAHHHQQQHQVQSNPLHLQQGHHYSGTTGVVNDVSETHLDDQDDCRIPSAPSGISTRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAGCPVTVATRKKCPACRFDKCLNMGMKLEAIREDRTRGGRSTYQCTYTLPANLLGGSSAQGGLPGQDKMSQGPCSPAPPGSEHHHSMKHHHSNHSHKMQLVPQLLQDIMDVEHLWHYNDNDRVGASQAMGSLNLAQSLPNSGMDNSPSGNSSSGDSLSGLGTSNGLTSSSSATNNGNLNSRSDLSRLTSSNSSTPTPIHEQQHSPSSNSAASSSNSANGNPTQHPDFLSNLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSMSTPGEIRVSLGKSITLEQAKQLGLATCIERMLAFTNNLRRLRVDQYEYVAMKVIVLLTSDTSELKEPEKVRASQEKALQALQQYTIARYPEMPAKFGELLLRIPDLQRTCQAGKELLSAKRAEGEGCSFNLLMELLRGDH*