Basic Information

Insect: Ormyrus thymus
Gene Symbol: Hr39
Assembly: GCA_035582935.1
Location: JAWWEM010000010.1:21410991-21420191[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 2 3.5e+04 -16.7 25.1 34 208 215 401 204 415 0.44

2 3 1.3 2.2e+04 -4.6 6.6 40 72 383 415 366 440 0.58

3 3 1.2e-76 2.2e-72 245.7 3.3 1 408 524 920 524 920 0.73

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	2	3.5e+04	-16.7	25.1	34	208	215	401	204	415	0.44
2	3	1.3	2.2e+04	-4.6	6.6	40	72	383	415	366	440	0.58
3	3	1.2e-76	2.2e-72	245.7	3.3	1	408	524	920	524	920	0.73

Sequence Information

Coding Sequence: ATGTCCGAACAGAGCGGGcccggggcggcggcggcggcggagcagcCTGGCCCCGCCTGGTGGCCGCCCGCCCAGCCCTGGAAGTCCTCCGGCTCGGGCCAGCCGGGCCAGGGGGCGAGCGGTGGCGCGCGCACCCAGCCCGAGCCCGGGAAGAACGTCTCCGTCACCACCATTAACGTACCTCCGCCCCTTCACGAGATGCACGACGGCAAGAGCGTGTGCAAGTACCTGGGCGGTCAGAACGGCGTGACGGTGTCGGTGGTGTCGACGAGCTCCCTGGCGACGGAGTCCGAGGAGGCCGACGCCGACAGCGACGGCGAGGTGAGCCGCATCGATTTTCGCGGCGTCAACCTGCGCACGAAGAAGAAGCGCGACGGCTCGCTCGAGCCCGGCGACAACAGCTGCGACCAGGCCCACCAGCAGCCCGAGCGGCCCATGTCCTGGGAGGGCGAGCTGTCCGACCAAGAAATGTCTTCCAATACTATCACCAACCAGGACCACGAAGAAACGTCAATGGAGGGCGTCCAGGTGTGCAGCTCGAGTCCAGGGCCGCAGGAGCAGAAGTTCCCGATCAAGCCGGAGCCGGACTTCCGCTCGAGTCCGGGGCTCCAGAGCCTCGGCGGCAACTCCCTGAACGAGACGATCGTCGCAGTCTCGCACGTCCAGCAGCTCcaccagcagcaccagcaggcCCACCAGCAGGCCCAGGGCCAGCAGCAGAGCATCGAGCAGAGCCAGCAGAGCGACCTGCCTCTGCTCGTCGGCAAGCTCCTCGGCGGCTGCAACAGCTCCACGCCCAATCACAGTCCCGTACTCGTTCCCCGGCACCACCTCACCAAGCACAGCCACACCAGATCTCAAGTCCCGTCGCCCGACTCAGCAATCCACTCGGCCTACAGCGTGTTCAGCTCGCCGACGCAGTCGCCGCACGCCGGCCGTCACTCGGCGCTCGGGCCAGGTTCCCCGGTGCCGTCGTCCTCCCTGTCGCTGTCGCGGCACAGCTTCAACAATTCGACGTCCTCGCtgtcgctctcgctctcgcactCGCTCTCGCGCAACAACTCGGACGCCTCGAGCAGCTGCTACAGCTACGGCTCGCTCAGCCCGCCGACGCACTCGCCGGTCCAGCAGCGACACGCGCACCACCACgcggcgcagcagcagcagcagcagcaacaacagcaacagcagcagcagcaccaggcCAGCGCGCTGCACCTGCAAGCTCAGGGGCATCATTACAGCGCGGCTCCCGGCGTCGTCGGAGACGTCGCCGACCCGCACCTTGACGACCAGGACGACTGCAGGATACCCTCTGCGCCCTCCGGGATCTCCACCAGGCAGCAGCTTATCAACAGTCCGTGTCCGATTTGTGGGGACAAAATCAGTGGCTTCCATTACGGGATATTCTCGTGCGAATCTTGTAAGggTTTCTTCAAAAGAACGGTGCAAAACCGCAAAAACTACGTGTGCCTTAGGGGCGCTGGCTGCCCGGTGACGGTCGCCACGCGCAAAAAGTGTCCAGCCTGCCGTTTCGACAAGTGCCTCAACATGGGCATGAAGCTGGAGGCGATACGCGAGGACCGTACACGCGGCGGTCGCAGCACTTATCAGTGCACTTACACGCTGCCGGCGAATCTGATGGGCGGCTCGGCCGCTGGTGGCCTCACCACCGATAAACTGGCCCAGGGTGGCGGCCCCTGCAGTCCAGCGCCGCCCGGCAGCGGCGAGCATCATCACTCGATGAAGCATCACTCGAATCATTCCCACAAGATGCAGGTGGTACCGCAGCTGCTGCAAGACATTATGGACGTCGAGCATCTCTGGCATTATAATGACAACGACAGACTCGGCAGCAGCAGTCAATCTGCGAGCTCGTTTAATCTCGCTCAGtcTTTACCCAATGCCGGAATGGGTAGCAGTACAAGTGGCAATAGTAGCAGCGGCGACTCGTTGAGCGGCTTAGGTGTACCGAACGGCCTGGGCAGTAGCGGCAGCAGTAATCTCGGTAGCTCGAACACAAATGGAAACGTAGTTAACAGCAGATCGGACGCCGTACGATCGAATTCGTCCGGTTCGGCGACGTCGACTCCGACCCAcgagcagcaacagcagcactCGCCCTTGTCGAACAGTGAAGCGAGCTCGAGCTGCTCGGCGAACGGCAATCCGGACTTTTTATCGAACCTGTGCAATATAGCTGATCATCGGCTTTACAAGATCGTCAAGTGGTGCAAGAGTCTGCCACTCTTTAAGAACATTTCCATCGACGACCAGATCTGCCTGCTGATCAACTCGTGGTGCGAGCTGCTGCTCTTCTCCTGCTGCTTTCGCAGCATGAGTACGCCCGGGGAGATAAGGGTGTCACTCGGCAAGTCCATCACTCTTGAGCAGGCTAGACAACTCGGTCTCGCTACCTGCATCGAGAGGATGCTGGCTTTCACGAGTAATCTAAGGCGTCTCAAGGTCGACCAGTACGAGTATGTCGCCATGAAGgTGATCGTGCTATTAACGTCGGATACAAGCGAATTGAAAGAACCAGAGAAAGTACGTGCCTCTCAAGAAAAAGCTTTGCAGGCGTTGCAACAGTATACAATAGCGAGGTATCCTGAGATGCCTGCGAAATTTGGCGAACTTTTACTTCGAATTCCAGATCTCCAGCGTACTTGCCAAGCTGGAAAGGAATTACTAAGCACGAAACGCGCCGAAGGCGAAGGTTATTCCTTCAATCTCCTAATGGAACTGCTTAGAGGGGAccactga
Protein Sequence: MSEQSGPGAAAAAEQPGPAWWPPAQPWKSSGSGQPGQGASGGARTQPEPGKNVSVTTINVPPPLHEMHDGKSVCKYLGGQNGVTVSVVSTSSLATESEEADADSDGEVSRIDFRGVNLRTKKKRDGSLEPGDNSCDQAHQQPERPMSWEGELSDQEMSSNTITNQDHEETSMEGVQVCSSSPGPQEQKFPIKPEPDFRSSPGLQSLGGNSLNETIVAVSHVQQLHQQHQQAHQQAQGQQQSIEQSQQSDLPLLVGKLLGGCNSSTPNHSPVLVPRHHLTKHSHTRSQVPSPDSAIHSAYSVFSSPTQSPHAGRHSALGPGSPVPSSSLSLSRHSFNNSTSSLSLSLSHSLSRNNSDASSSCYSYGSLSPPTHSPVQQRHAHHHAAQQQQQQQQQQQQQQHQASALHLQAQGHHYSAAPGVVGDVADPHLDDQDDCRIPSAPSGISTRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAGCPVTVATRKKCPACRFDKCLNMGMKLEAIREDRTRGGRSTYQCTYTLPANLMGGSAAGGLTTDKLAQGGGPCSPAPPGSGEHHHSMKHHSNHSHKMQVVPQLLQDIMDVEHLWHYNDNDRLGSSSQSASSFNLAQSLPNAGMGSSTSGNSSSGDSLSGLGVPNGLGSSGSSNLGSSNTNGNVVNSRSDAVRSNSSGSATSTPTHEQQQQHSPLSNSEASSSCSANGNPDFLSNLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSMSTPGEIRVSLGKSITLEQARQLGLATCIERMLAFTSNLRRLKVDQYEYVAMKVIVLLTSDTSELKEPEKVRASQEKALQALQQYTIARYPEMPAKFGELLLRIPDLQRTCQAGKELLSTKRAEGEGYSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00079965;
90% Identity: iTF_01110995;
80% Identity: iTF_01113504;