Basic Information

Insect: Agrochola lota
Gene Symbol: egg
Assembly: GCA_947364205.1
Location: OX376246.1:7891179-7946336[+]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 1.2e-12 3.7e-09 36.5 0.0 4 73 1967 2029 1964 2033 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	1.2e-12	3.7e-09	36.5	0.0	4	73	1967	2029	1964	2033	0.88

Sequence Information

Coding Sequence: ATGAGTGATAAAGAAGAAAAAAGCAGTAATGATGAAGAAAAAACACGAATAATTCAAGACGAAGGTAGCAAAAACCCAAAAATAACAACTGAGGGTAATGTATCTTTAGATTCCAATAAAAATACCGAAACTAGCAGCGCTATTTATGAAAATATGCCTCAGTCAGAAGCTATAGAAGGGTCTGGAGATGACAAAGGACGCATTCAACAAGAGAACTTAGAACCTGATGAATTAGAAGCAGAGTTGACAGATACGTCTAAAGAATTCATAAATATTAGAGCGGGCGAAGGTTCTGGTGACTATACAGCCAAAGCAAAGGTCAGTAGAATAGATGACAAAGAAATTGAGGACGACACTGAAATTGATGCAAAAACATCAAAATCCAATGTTACTGATGAGAAAGATGAAAGCAAAGACAGCTTCGTCAACAAATATGATAAAATTGAATCTGAGAAGGCTGATGATCTTGACGAAATTGAAGATGACGATATGGAACTAAGATGGGATGATGATGATTCCAGCAATCAAGCTAAGGATGGTGATAATGAAAATGCAGACGCTAAGAATGATATGCTGTCGGAAGATCAACTTTTGGAAGAACCTTCAGATGTTTTAACTAAAGATATGACTGAAATGCCTTCTGATTGGGATCCCAAAGTTTCTGAAGCCAATCTTGACAGTAATGTATTAAAAGTCAACAGCGAAGAAAATATTCTTACTAGGAACAATAATCCCAAGGAAATTGAAGCTAACGAAGAATCTGAAATTAGTCCAAAACTGGACATTCCTACAGATAAGGCTGAATATGAGAAAAGCTTGGGAGATGAGATTTTAAGGGAAAATGATTTAAATACTGAAGCTATAAATAGCCCAGAAATGGACTTTTCTGCAGAAGACAGTATGGATCGAGATGACGAAACAAGTTTGGGAGATAAGCTTTTAGGGGAAAACGACTTAAATACTGAAGCAATAAATAGCCCAGAAATGGACTTTCCCGCAGAAGAAAGTATGGATCGAGATGACATCAATGTTTTAGAAGATAAATTATTGGAAGAATCTGAAATTGACACTGAAGCAACAGTAATAGCTCAAGCAAAAGAGATTCTTGAAGAGAGAAATTTGGATGAACAAATAAAAGAGACAGAATCTGCAAAAGACAATCTTCTAAAGGAGGTTACTAATGATGAACAGAGAAAAGAAGATCCAGTTGACATTATTGAAGATCAACTTTTAGCTGAATCTGAAAGTAATATTGAAATGGAGTCTTCAACATTGAAGTTGAAATCTTTTACAGATGTCATCTTTAACAAAGATAATGATATGATGTCAGAAGAAAATCTCTTAGAAGAACCTGATTCTAAAGGCGAAAGTTCTTTGATTATATCTGAGAAACATATTGAATGTTCTGAAATTGTTCCTGAAAAAGAAGCCCCTATGAATAAAGAAGATAATGATGATGTTCTGCTAGAAGAAAAACTATTACAAGAAACAGAAACAGCTGAAGTAATTCCAGAAAGTGATATAACAATGGATGTTGATGATGAGGAAGAAGGGGAGTTACTGAAAGATGATGAATGTCAAGAAGATAGCTCTACTCCTATGGATGTTGATATTACTGATACATCTATTGAAGATAAGGCTAAAGTAGAAGACAAGATTATAAATCAAACAATCAATCAATCTGAAGTGGAAAACAAAGGTATATCTCTCCCAATAGATGGCCAAACTAATATTGAAAAGGTAGATGAAGTTAAAAATATGGATCAAACTGATGATCACAGCAAAGTAATTGAGAAAGATATTGATCAGCCAATTAAAGATACAACTAAAGCAGTAGACATAATTAATGATACCTCTTCTATTGAAGATGAACCTAAAATCGATGAGAATATCGAAGATCAAGCTATGACTGAAAAAGAGACTATTGATCAACAAATTGATGATGAAACTAAGATGGAAGACAGCAATAAAGATAAATTAATTCTATCTAATACGAAAGAGCAGTCTATTAAGAGTCCTGTACAAATAGATGGACTCACTGTTTCTGATACTTCTAACATTCTCGTTGAAGATCTAAAAAAATCTACCCCAGAAAAAACTATTCTTGTAAAAGAAATTGAAGGTAAAACAGATACCGAAAATACTGAAAATATAAGCACTGATTTAGATAAACCTGAAAAAAGTAAAGAAACCATCATTCCAGATAGTAGCTCAGATAAAAACCAACAGTTTGATGAAATTTCACCCAACAACTCGTCAATATTTCCAGAAGATTCTTGTCCTATCAAAACTGACCACGGTTTACATAAACCAGATATGATGTTAGAAATACCTTCACAAGAATTGATTGACATGGATGATACAGATTTCTCTATGAATCTAGACAATTCTGAAGTGATTGACAGTCTTAATGATGTTGACAAACATGTTGATGATGACATAGTACATGAGAAAACAATTGATAAAACTGTCATTGATGATGTTTTAGTAAGTGATAAAATTGACACTGATGGCGGTACAGTCAGTGAGAAATCAGTAAATAATACTATAGCTGATGATGTCTCAGTAAAACCGAAACCGGTAGATGAAAAAGCCATAGCTACTGAAATAACAGCTGTTGATAAAACCGTTGCTGATGATGACACAGTAAAAGAGAAATCAATAGTTCAAGAACCCATAGTAACTGAGTCAACAGAAAGTAATATTGTGGAAAGTGACAAGAAAGTTGAAGATGCAGTTGTTCAATCAACAGTTGAAGAAAACATGGAAAAAATGTTTGCGGATGAGCCGGAAGTTGCAAAAGAAATTGCAGAGTGCATTGCATCCACAAGCCAAGCTGAAGGCCCCACTGAACATCCATCGACAACCATAACCCGTATGACTCCAGACACATCGGATGAAGTTCCAGAGATTGATGACAGCCTGGGACTGTTGGCTGAGTCTGCGGGACGGATGATGGAGGATGATGAGGAGCCTGATGATGATTTTGATGGTGATGATGATGATGATTTTGATCATGATGAAAGCAGCAACCAAATCTCAGCCGAACAGTCCGAGGACTCGAACCCAGCAGCCCTGGAAACTGAACCAGTTAGAGACCAAGAAGACAAGGAGTTGGAGACTCCAGACCCTAAGGATGAAGAGTTTCCCTTCATGACGTGTGATAGCACCTCCCAGGATAAGGCGGAGAAGATGGATGTAGAAGAGGAATATGGGACGGTGGAATTACAAGCAGAAACAGTTAATGAGATGAACGAAGAGGCGAAGTCGGCAGTTGATGCGTTGTTGAACGCCGATAACCCCGCCGATGAGCAAGCTGAGAACCAACAAGAAACCACAGATCAGATGGACATAGAGACAGTGAAACTGTCAGATACGTCTGACAACGAGGTCGATGTTGAACCTACTAAGGTTCAATCGACTGTGGCTGAACCAAGCAAAGAGACTGAAGAAAAACAAAAGTCATCACCATCTAAATCTCCGAACAAGAGCAATATATCGCCCAAGCAATCGCCAAGCAAGTTAAGACAGTCGCCCTGTATGCAATCCCCAAGCAAGATGAAGAATTTGGCTATCACCGCGCAAGAAGCTAGCTCTGTTGTTAACATTGTAGATTTGGAGGAGAGCAGTTCTTCTGAAGATGACATACAAGAAGTACAAAAGCAACAGAAACCAGAGACAACAGAGGACGACAAATCTCCTTCCCCGGAATCAGATGTTACCAACGTTAACATACCAACGGGTATTGACATCATGTGTACCTCCGGCGGAAATACGTCAGCGATAACGACTAAAGACAACCTGTCCCAGGTTGTTATTAGTGGAGTGCCTAAGCCGCCGCCGCATAAGCCTGCCAGATTAAATACTAGTGAAGTTACAATCAAAACTGTTAGCAACACCGAACCATTGGTTATACCTGAAACTAAGGTTAATGAACAGACTCCAACACCGTCTAAACCTAAACTGAGCCTAGAAATATTCAGTCTGGACTCTGACGAGGATGAAAGTGGAGCTAAAGCTTCCCCCGACAAAATGACAGATTTAGAACTAGAAAAAGCTCGAGAAACATCCAAGTGTATCAACTATTTTTGCACAAGTGACAGTAAAGTGCCTAACAAGCAGGCGGAGGCGTCAGTGGTCGCGTACTACGACGCGGGCAGGAAGAGACGCTCCGTGGTGTGCCAGCCATGCGCCGATGTGGTCGCTGCTAGGACTAAGAATCTAATTCAAGGCATTAAAGATCTAACTCCACTGTTAGACCTGGATATGGGCAAGTTGTCACAAGACCTGGTGGAGATATCTGACTCGGAGTCCGAAGATGAGGACATGACTCCGGAAGAACCTAAGGAGAGTATTGGAGAGAAGGGAGCTAAATTCGTAGAAGACAATCTGACCAAGTTTTTGAACGACACTTGGCAAAAATACGACATGGACGCGCGACTCAAAGAGACACAGATCATGTTGGATGATGAGATTGAAAAACTTGAACAGGACAGTAAAGAGATAGACGCAATGCTAAACGAGTGCCAGGTAGCGACAGACAAGCTTCGCTGCGAGTTATATGCGACGTTCGAGTGTCGGCGTCAACAACAACCCTCCTTAGTTATATGCGACACGCCTGACTCTAAATATATCGGACTAGAAGAGCAAATAAACCCTCCAGCCGCTGCCGAATCAATTGAAACTCGTCAAGCCAAGCGTCGACTGTCGTCAACCAGTGAGACTCCAGCGAAACGTCCTGCCATACCTCTTGGATATGCTCCTTTAGATGCCAGCGACGCTAAGAAAGACATATCAGTAGTGAAGCTCTCAGCGGAAGCCGCTCCCGCAGACCTACCTCCCCCTGGAGAGATATCCCGCCCTCCCCTGCGCGTGGGCATGCCGGTCTACGCTATGAAGAACGCCTTCGGACCCTGGCTTAAAGGCAGAGTGGTAGAGATACAGCCCAAGAATACGAGTGGAGGCAACCCCTTCTCTCTGTGTCTTGTGAAATTCGACCATAAAGTCAAGACGAATGGGAAAGTATTGCAAGCGAGATGCATAGCGTATTCTGAGCCCGCTGATGTCAGAATGACTATTGGTACTCGTCTTATAGCCCTGTTCAAGGATTCGAACAAGCGTGAATCTTACTACTCAGGTGTTGTGGCTGAAATACCCAATCCAGTCAATAATTATAGATATCTGGTATTCTTCGACGACGGCTACGCTCAGTACGTCCAACATCAATTTACCCGCCTTGTCTGCGAAAGCTCCCCCTTAGTATGGGAGGAAGTACATCCGTTCTCGCGGGAATTCGTGCGCGAGTACCTGCTGGCGTACCCAGAGAGACCCATGGTCAGGCTGCATGAGGGACAGCATCTGAAGACTGAGTGGAACGGGAAATGGTGGTCGTCCCGAGTGACCCGCGTGGACGCGTCGCTGGCGCAAGTGATGTTCGTGGGCGACGGGCGGCGCGAGTGGGTGTACCGCGGCTCCACGCGCCTCGCGCCGCTCTACCTGGAGCTGCGCGCGGCCGAGCGGCATCGGCCGCGCCCCATGCCCAGGAGCAAGGCGCAGCCCCGGTTCAATATGCCGTACGTGGAGTACACGCGGTCGGATGAGCCGGAACCGAGCAAGCCAGTGGATGCGCAAGCGCAGCAACAACAGCAGCAGCAACAGCAAATACAAAATGAGGAGATACGTCGCCAACGCGCCGTGGCCAAGAAGTCAACCTCAGCACCTCCTCAAGTGCTCCCGCCTTCACAACAGATCATGCCCCCTACACACATGGATCCTGTCACCAGCAGAGTTGTGTACTACACACCAAAGAATGCAGTGAGACCGTTGAAGATGGTGCCTCACAGATGCGGTCCAAGATGCAAGCGAAGCGACGTACTCTCACTAAAAGAGTTGAGGACTTATAACCCATTAGCAAAACCTCTGCTCAGCGGATGGGAAAGGCAAATAGTTCGCTTCAAAGGCCACAAAGAAGTGATGTACCGCGCACCCTGCGGCCGTCGCTTACGAAATATGCGCGAGTTACATCACTACTTACGATCCATAGACAGCGACTTGCCTGTAGATCTGTTTGACTTCCACTACTCAACACATTGTCTAGCGGAGTTCGTGCTCAACAAATGTCTTGTGGGGAAAAAGGATCTCTCCCACGGCAAAGAGAACGTCCCAGTGCCCTGCGTGAACTACTACGACGACTCCTTACCCGAGTTCTGCTCGTACAACACAGAACGCACTCCCACCGCTGGCGTGCCGCTCAACCTGGAGCCCGAGTTCCTGTGCGGCTGTGACTGTACCGACGACTGTCAGGATAAATCAAAATGTGCTTGTTGGAAAATGACGCTAGAGGGCGCTCGAACCATCGGGCTTCGTGGACCTAACGTGGGCTATGTTTATAAGAGACTGCCCGAACCGTTACCTTCTGGAATATACGAGTGTAATTCTAGGTGTAAATGCAAGCATACATGTCTCAACCGCGTAGCGCAACACCCACTACAATTAAAATTACAGGTTTTCAAAACCCCGAACCGTGGTTGGGGTATCAGGGCGCTGAACGACGTTCCAAAAGGCTCCTTCCTTTGTGTGTATGCTGGTAACCTGCTCACTGATGCTACTGCTAACTTGGACGGTTTGAACGAAGGCGACGAATACCTAGCAGAATTAGATTACATTGAAGTAGTCGAACAAATGAAAGAAGGATATGAAGAAGATATTCCTGAGGCTGATAAGAAATTAGACAAGAAAGATGCTAAGGATGATGAGGAAAGTGACGAGGAGGAACCTTCATCCTCCGAGGATGAGGAGAAGGCGGATAAGAATGACAAAGAGGATGATGACTTTAGACCAGGATACATTGGACTAGGCGTGACGGAGTTCAACAAACGCCTCCGTAAACGCGAGAAATCAAAGAAAGATAAAGAAAAATCGGCGACTGATGAGAAAGAAAAGGAGAAAGATACGACTAAAGAAGCGAATGCTGAAGAGGATTGTATTACTATTAGTGATGATGAAGAAGTCCGAGAACCATCGAGATTCATGGCTCAAACGAACATGGGAGCGAACGAGTATATTTCTAAATACAAGTCTGTTCGCACGTTGTTTGGTATGGACGAGGCGTGCTACATCATGGACGCTAAGGTTCAAGGCAACATTGGCAGATATCTCAATCACTCCTGCTGCCCGAATGTCTTCGTACAGAACGTGTTCGTGGACACCCATGACCCTCGCTTCCCCTGGGTGGCGTTCTTCGCGCTATCACACATCAAAGCAGGTACCGAGCTCACTTGGAACTACAACTATGACGTGGGTTCCGTTCCCGGGAAGATACTTTACTGTTACTGTGGAGCTCCTAACTGTAGGGGACGGTTGTTGTAA
Protein Sequence: MSDKEEKSSNDEEKTRIIQDEGSKNPKITTEGNVSLDSNKNTETSSAIYENMPQSEAIEGSGDDKGRIQQENLEPDELEAELTDTSKEFINIRAGEGSGDYTAKAKVSRIDDKEIEDDTEIDAKTSKSNVTDEKDESKDSFVNKYDKIESEKADDLDEIEDDDMELRWDDDDSSNQAKDGDNENADAKNDMLSEDQLLEEPSDVLTKDMTEMPSDWDPKVSEANLDSNVLKVNSEENILTRNNNPKEIEANEESEISPKLDIPTDKAEYEKSLGDEILRENDLNTEAINSPEMDFSAEDSMDRDDETSLGDKLLGENDLNTEAINSPEMDFPAEESMDRDDINVLEDKLLEESEIDTEATVIAQAKEILEERNLDEQIKETESAKDNLLKEVTNDEQRKEDPVDIIEDQLLAESESNIEMESSTLKLKSFTDVIFNKDNDMMSEENLLEEPDSKGESSLIISEKHIECSEIVPEKEAPMNKEDNDDVLLEEKLLQETETAEVIPESDITMDVDDEEEGELLKDDECQEDSSTPMDVDITDTSIEDKAKVEDKIINQTINQSEVENKGISLPIDGQTNIEKVDEVKNMDQTDDHSKVIEKDIDQPIKDTTKAVDIINDTSSIEDEPKIDENIEDQAMTEKETIDQQIDDETKMEDSNKDKLILSNTKEQSIKSPVQIDGLTVSDTSNILVEDLKKSTPEKTILVKEIEGKTDTENTENISTDLDKPEKSKETIIPDSSSDKNQQFDEISPNNSSIFPEDSCPIKTDHGLHKPDMMLEIPSQELIDMDDTDFSMNLDNSEVIDSLNDVDKHVDDDIVHEKTIDKTVIDDVLVSDKIDTDGGTVSEKSVNNTIADDVSVKPKPVDEKAIATEITAVDKTVADDDTVKEKSIVQEPIVTESTESNIVESDKKVEDAVVQSTVEENMEKMFADEPEVAKEIAECIASTSQAEGPTEHPSTTITRMTPDTSDEVPEIDDSLGLLAESAGRMMEDDEEPDDDFDGDDDDDFDHDESSNQISAEQSEDSNPAALETEPVRDQEDKELETPDPKDEEFPFMTCDSTSQDKAEKMDVEEEYGTVELQAETVNEMNEEAKSAVDALLNADNPADEQAENQQETTDQMDIETVKLSDTSDNEVDVEPTKVQSTVAEPSKETEEKQKSSPSKSPNKSNISPKQSPSKLRQSPCMQSPSKMKNLAITAQEASSVVNIVDLEESSSSEDDIQEVQKQQKPETTEDDKSPSPESDVTNVNIPTGIDIMCTSGGNTSAITTKDNLSQVVISGVPKPPPHKPARLNTSEVTIKTVSNTEPLVIPETKVNEQTPTPSKPKLSLEIFSLDSDEDESGAKASPDKMTDLELEKARETSKCINYFCTSDSKVPNKQAEASVVAYYDAGRKRRSVVCQPCADVVAARTKNLIQGIKDLTPLLDLDMGKLSQDLVEISDSESEDEDMTPEEPKESIGEKGAKFVEDNLTKFLNDTWQKYDMDARLKETQIMLDDEIEKLEQDSKEIDAMLNECQVATDKLRCELYATFECRRQQQPSLVICDTPDSKYIGLEEQINPPAAAESIETRQAKRRLSSTSETPAKRPAIPLGYAPLDASDAKKDISVVKLSAEAAPADLPPPGEISRPPLRVGMPVYAMKNAFGPWLKGRVVEIQPKNTSGGNPFSLCLVKFDHKVKTNGKVLQARCIAYSEPADVRMTIGTRLIALFKDSNKRESYYSGVVAEIPNPVNNYRYLVFFDDGYAQYVQHQFTRLVCESSPLVWEEVHPFSREFVREYLLAYPERPMVRLHEGQHLKTEWNGKWWSSRVTRVDASLAQVMFVGDGRREWVYRGSTRLAPLYLELRAAERHRPRPMPRSKAQPRFNMPYVEYTRSDEPEPSKPVDAQAQQQQQQQQQIQNEEIRRQRAVAKKSTSAPPQVLPPSQQIMPPTHMDPVTSRVVYYTPKNAVRPLKMVPHRCGPRCKRSDVLSLKELRTYNPLAKPLLSGWERQIVRFKGHKEVMYRAPCGRRLRNMRELHHYLRSIDSDLPVDLFDFHYSTHCLAEFVLNKCLVGKKDLSHGKENVPVPCVNYYDDSLPEFCSYNTERTPTAGVPLNLEPEFLCGCDCTDDCQDKSKCACWKMTLEGARTIGLRGPNVGYVYKRLPEPLPSGIYECNSRCKCKHTCLNRVAQHPLQLKLQVFKTPNRGWGIRALNDVPKGSFLCVYAGNLLTDATANLDGLNEGDEYLAELDYIEVVEQMKEGYEEDIPEADKKLDKKDAKDDEESDEEEPSSSEDEEKADKNDKEDDDFRPGYIGLGVTEFNKRLRKREKSKKDKEKSATDEKEKEKDTTKEANAEEDCITISDDEEVREPSRFMAQTNMGANEYISKYKSVRTLFGMDEACYIMDAKVQGNIGRYLNHSCCPNVFVQNVFVDTHDPRFPWVAFFALSHIKAGTELTWNYNYDVGSVPGKILYCYCGAPNCRGRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01094945; iTF_01093126; iTF_00758193; iTF_01094065; iTF_00122423; iTF_00745723; iTF_00907911; iTF_00038799; iTF_00726387; iTF_00364052; iTF_01439961;
90% Identity: -
80% Identity: -