Olat009638.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Oligia latruncula
Gene Symbol
egg
Assembly
GCA_948474745.1
Location
OX419711.1:3878564-3929552[-]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 4.2 1.4e+04 -3.9 0.1 29 38 1957 1966 1928 1967 0.72
2 2 1.7e-12 5.5e-09 35.9 0.0 4 73 1998 2060 1995 2064 0.87

Sequence Information

Coding Sequence
ATGAGTGATAAAGAAGAAAAAAACAGTAATGATGAAGAAAAAACGCGAATAAATCAAGACGAAGGCAGCAAAAACCAAAAATTATTAACTGAGGGTAATGTATCATTAGATTCCTCCGATAAAAATACAGAAAATATTGGCGCCATACCTGAAAATGTGCCTAAAGGGGCTGGAGATGATAAAGCGCGTATTTTACTAGATAACTTAGAACTTGACAAAATAGAAGCGGAGTTGACAGAAATGTCAAAAGAAATCATAAATACTGATGCAGGCAAAGATGCTGGTGACTATACAGACAAAGCAAAAGTCAGTGCAATAGATGTTAAAAAAATTGAGGATGTTAACACTGAAGTTGATGCAAAAGTATCTAAAACCAATTTTACTGTTAAGAAAGATGAAAGCAATGATACTTCCCTCGGCAAAGGTAATGCAAAGGAATCTAAGAAGGCTGACGATCTTGATGAAATTGAAGATGATGATATGGAACTAAGATGGGATGACGATGATGATGATGATGCTAGCAATCATGCTATGGGTGATGATAATGGAAACGCAGACACTAAGAATGATGATATTCTGTCCGAAGGCCAACTTTTGGACGATCCTTCAGATGTTTTAATTAAAGATATGACTGAAACACCTTCTGATGGGAATCCTAAAGTTTCTGAAGCCAATCTTGATAGTGATGTCTTAAAAGTCAACAGTGAAGAAAATAGTCTTACAAGAGATGATAATACTACAGAAATTGAAACTACTAAAGAATCAGAAATTAGTCCAAAACTGGACATTCCTAAAGATGAAAAAATCTTGGCAGATATGTGTTTAAAGGAAAACTACTTTACTGAAGAAATAAATAGCCCAGAAATGGATTTTTCCGCAGAAAATAGTATGGATCGAGATGATATTAATGTCCTAGAAGAGAAACTATTGCAAGAATCTGAAAATACTGAAGAAATAAATAGCCCAGAAATGGTTTTTTCCGCAGAAGAAAGTATGGATCGAGATGATATTAATGTCTTAGAAGAGAAACTATTGGAAGAGTATGAAATTGTCAATGATGCAACAGTAATAGCTCCGGCAAAAGACATTCTTGAAGAGAAAAGTATGGACGAACCAATAAAAGAGACAGAATCTGCTAAAATCAATCTTCTAACGGAGGTTACTAATGATGAGCAGACAAAAAAAGATCCAGTTGCAATTATTGAAAAAGACAAACTTTTAGCTGAATCTAAAAGTAATACTGAAGCGGAGTCTTCAACATTGAACTTGAAATCTTTTACAGATATCATCTTGAACAAAGATAATGATGATATTATGTCAGAAGAAAAGCTTTTAGAAGAACCTGATTCTAAGGACGAAAGTTCTTTGATTATTTCTGACAAAGTTATTGAATGTTCTAAAATAGTTCCTGAAAAAGAGGCCCCAATGAATAAAGTAGATGATGATGATGCTCTGCTAGAAGAAAAACTATTACAAGAAACGGAAACAGCTGAAATTATTCCTGAAAGTGATATAACAATGGATGTTGATAATGAAGAAGAAGGAGAGTTACTGAAAGATGATGAATGTCCAGAAGATAGCTGTACTCCTATGGATGTGGACAATACTGACACATCTATTGGAGATCAGGCTAAGGTAGAAGACAAGATTATAGATCAAACAATGAATCAATCTGAAGTAGCAAAGAAAGGTATAATTCTGTCAATAGAAGACCAAACTAATATAGAAAAGGTAGATGAAACAACAGGTGAAGTTAAAAATATGGATCAATCTGATGATCAAAGCAGAATAATTGAGAAAGTTATTGATCTGCCAATCAAAGATACATCTAAAGCAGTAGATATTGTTAAAGATATACCTATGGAAGATGAAGTTAAAATTGATGAGGAAATTGTAGATCAAGCTGTAACTGAAAAAGAAAGAATTGATCAACAAATGCAATGCAGCAATGAAGATCAATTAATTCTTGAATCAAATGCAAAAGAACAGTCTATTAAGAGTCCTGTACAAACAGATGCACTCACTGTTTCTAATACTCTTAACATTTTAGTTGAAGATCTAGAGAAACCTATCCTGGAAGAAACTACTCTTGTAGAAGAAATTAAACTTAAAACAGACCCAGAAGAATTTAAAGAAAATACTGAAAATAAATACAAAGACACTGATTTAGACAAACCTGAAAAAAATAAAGAAATTATCAATCCAGACACTAGCTTCGATAACAACAAGGAGGTTGATGAAATTTTATTTTCTAACAACTCTTCAATATTTCTAGATGTTTCGTGTCCTATCAAAACTGACCATGGAGTACATAAACCAGACGTGATGTTAGAAATACCTACACAAGAACTAATTGACATGGATGATACAGATTTGTCTATGAATTTAGACCATTCTGTAATGATTGACGGTCTTAATGATGTTGACAAAAACGTTGATGACGACATAGTACATGACAAAACAATTGATGAAACTGTTGTTGATGATGTCATAGGAAGTGATAAAATTGTTACTGATAATGCTACAGTCAGTGAGAAATCAGTAGAACAAGCTAATGTAGATGAAGACACAGTAAAAGAGAAACCAGTAGATCAAAAAGCCTTAGCTACTGAATCAACAGTTCTTGATAAAATCATAGCTGAAGATAATGCAGAGAAACCAGTAGATCAAAAAGCCATAGATATTGAAATGACAACTGTTGATAAAATGATTGCTGATGAAGACACAGTAAAAGAGAAATCAATAGTTCAAGAAGCCATAGTAACTGAATCAACAGTAGGTGAAGTCCAAACAGTAAGTAATATTGTGGAAAGTGACAAGAAAGTTGAAGATACTGTTGTTCAAACAACAGTCGAAGAAAACATGGAAAAATTGTTTGCAGATGATGAGCCAGAAGTTGCTAAAGAAATAGCAGAGTGCATTGCATCCACAAGCCAAGTTCAAGTCCCCGCCGAACAGCCATCAGCATCCATAACCCGTATGACTCCAGACACATCGGATGAAATTCCAGAGATAGATGACAGTCTGGGTCTGTTGGCTGAGTCTGCAGGACGGATGATAGAAGATGATGAGGAGCCTGATGATGATTTTGATGATGATGATGATTTTGATAATGATGAAAGCAGTAACCAAATCTCAGCAGAACAGTCGGAGGACTCGAATCCTGCAGCATTAGAGTCTGAACTAGTAATAGACCAGGAAGACAAGGAGTTGGAGACTCCAGATCCTAAGGATGAAGAGTTCATGACGTGTGACAGTACATCCCAGGATAAGGCAGAGAAGATGGAAGTGGAAGAGCAATATGGGACCTTGGAGTTTCAGGCGGAAACAATAAATGAAATGAATGAAGAGGCAAAGTCGGCTGTTGACGCGTTGTTGAACGCTGATAACCCCGCCAGTGAACAAGTTCAGGATCAACAAGAGACAACAGACCAAATGGACATAGAGACGGTGAAGCTGTCAGATACGTCTGACAACGAAGTTGATGTTGAACCTACAGAAGTTCAACAGCCCGTGGCTAAATCAAGCAACGAAGAAGAAAAACAAAAGGACTCGCCTTCTAAATCACCGAGCAATAGCAATATATCGCCCAAGCAATCGCCAAGCAAGTCAAGCCAGTCGCCCTGTAAGCAATCGCCGAGCAAGATGAAGAATTTGGCTATCACCATGCAAGCACTTAGCGCGGTTGTCAATATTGTGGATTTAGAGGAGAGCAGCTCTTCCGAAGATGATATTCAAGAAGTACAAAAGCAACAGGAGCCAGAACCAACACAGGACAACACAGCTCCTTCCCCGGAATCGGATGTTACTAACGTTAAAATACCAACGGGCATAGACATAATGTGTACTTCCGGCGGAAATACGTCAGAGATAACGACTAAAGACAACCTCTCCCAGGTTGTTATCAGTGGCGTGCCAAAGCCGCCGCCACATAAGCCTGCTAGATTGAATACCAGTGAAGTTTCAATCAAAACTGTTAGTAATACAGAACCATTGATTATACCTGAAACTAAGATTAATGAACAGACTCAAACACAGTCTAAACCTAAACTAAGTCTAGAAATATTCAGTCTAGATTCTGACGACGATGAAAGCGCTGCTAAAGAAAAACCACCAACAACACCCCCTCACAAAATGACGGCCTTAGAACTAGAAAAAGCTCGAGAAACATCCAAATGTATCAACTATTGTTGCACGAGCGACAACAAAGTGCCTTACAAGCTGGCGGAGGCGTCAGTGGTCGCGTACTATGACGCGGGTAGGAAGAGACGCTCCATGGTATGCCAGCCATGCGCCGATGTGGTCGCTGCTAGGACTAAGAATCTAATTCAAGGCATAAAGGATCTAACTCCACTTTTAGACTTAGACATGGGCAAGTTATCACAAGACTTGGTGGAGATATCCGACTCGGAGTCTGAAGATGAGGTTATGAGTACTGAGGAACCCAAGGAGAGTATCGGAGAGAAGGGGGCTAAATTCATAGAAGACAATCTGGCCAAGTATTTGAACGAAACATGGAAAAAGTACGACATGGACGTACGCCTCACGGAAACACAGATTATGTTAGATGATGAGATTGAAAAACTTGAACAGGACAGCAAAGAAATCGACGCAATGCTAAACGAGTGTCAGGTAGCGACAGACAAGCTTCGCTGCGAGTTGTATGCGACGTTCGAGTGTCGGCGACAAAAACTACCCTCCTTAACCATATACGACACGCCTGAGTCTAAAACTCGTCAAGCGAAGCGTCGTTTGTCGTCAACCAGCGAGACTCCAGCTAAACGTCCCGCTATACCACTTGGATACGCACCTTTAGATGGCGGCGACTCTAAGGAAAAAGCAGCAATCCCGGCGCCAGATAATAAACTAGATGATGACAAAGACATATCAGTAGTGAAACTGTCAGCGGAAGCCGCCCCCGCAGAGCTGCCCCCCCCCGGCGAGATCTCGCGCCCGCCGCTGCGCGTGGGCATGCCGGTCTACGCCATGAAGAACGCCTTCGGACCCTGGCTTAAAGGCAGAGTGCTGGAGATACAGCCCAGGAATCCATCTGGGGGCAACCCATTCTCTGTGTGTCTTGTGAAATTTGACCACAAAGTTAAGACTAATGGGAAAGTATTGCCTGCAAGGTGCATCGCGTATTCTGAGCCCGCTGATGTAAGAATGACTATTGGTACTCGTCTAATAGCGCTGTTCAAGGATTCGAACAAACGTGAATCTTACTATTCAGGTGTTGTAGCTGAAATACCAAATCCAGTCAATAATTATAGATACCTAGTATTCTTCGACGATGGCTACGCTCAGTACGTCCAACACCAGTTCACCCGCCTAGTCTGCGAGAGTTCCCCCTTGGTATGGGAGGAAGTACATCCATTCTCGCGGGAATTCGTCCGCCAGTACCTAATGGAGTATCCAGAGAGACCCATGGTCAGGCTGCATGAGGGGCAGCATCTGAAGACTGAGTGGAACGGAAAATGGTGGTCATCCCGAGTGACCCGCGTGGACGCGTCGCTCGCGCAAGTGATGTTCGTGGGCGACGGCCGGCGCGAGTGGATCTATCGCGGGTCCACGCGCCTCGCGCCGCTCTACCTCGAGCTGCGCGCGGCCGAGCGACACCGGCCCCGGCCCATGCCGCGCAGCAAGGCGCAGCCTAGGTTCAATATGCCGTACGTGGAGTACACTCGGTCGGATGAGCAGGAGTCGAAAAAGCAAGTGGATGCGCAGGCGCAGCAACCGCAAGAACAGCAGCAGCAGCAGATACAAAATGAGGAGATACGTCGCCAACGTGCCGTCGCCAAGAAGTCTACCTCAGCACCTCCTCAAGTGCTCCCGCCATCACAGCAGGTTATGCCCTCAAGCTTGGATACTGTCACCAGCAGAGTTGTGTACTACACACCAAAGAACGCGGTGAAACCATTGAAGATGGTGCCACACAGATGTGGTCAGAGATGCAAGAGAAGCGATGTACTCTCACTGAAGGAGTTGAGGACTTATAACCCTCTAGCTAAACCACTGCTCAGCGGATGGGAAAGACAAATTGTCCGCTTCAAGGGCCACAAGGAAGTGATGTACCGAGCGCCCTGTGGGCGTCGCCTACGAAACATGCGCGAGTTACATCACTACTTACGTACCATAGACAGTGACTTGCCTGTGGATCTGTTCGACTTCCACTATTCTACGCATTGTCTGGCGGAGTTCGTGCTCAACAAGTGTTTAGTTGGGAAAAAGGACCTCTCCCACGGCAAAGAGAACGTCCCAGTACCCTGCGTGAACTACTACGACGACTCCTTACCGGAGTTCTGTTCGTACAACACCGAGCGCACTCCCACCGCCGGCGTGCCGCTCAACCTGGAGCCCGAGTTCCTGTGCGGCTGCGACTGTACCGACGACTGTCAGGATAAATCAAAATGCGCTTGTTGGAGAATGACGCTAGAGGGCGCTCGCACCATCGGCCTCCGTGGGCCTAACCTGGGCTATGTGTACAAGCGATTGCCTGAACCGTTACCTTCTGGGATATACGAGTGTAATTCTAGGTGTAAATGCAAGCACACATGTCTGAATCGCGTGGCGCAGCATCCACTACAATTAAAATTACAGGTGTTCAAAACTCCAAACCGTGGTTGGGGCATCCGGGCACTGAACGACGTGCCAAAGGGCTCGTTCCTATGTGTGTACGCTGGTAACCTACTGACTGACGCTACAGCTAACTTGGACGGTTTGAACGAGGGCGACGAATATTTAGCAGAATTAGATTACATAGAAGTTGTGGAACAGATGAAAGAGGGTTATGAAGAGGACATTCCGGAGGCTGACAAGAAATTAGACAAGAAAGAAGGTAAAGATGGCGATGACAGTGACGAGGATGACCCGTCATCCTCCGAGGATGAGGAGACGGCCGATAAGACTGACAAGGAAGATGATGACTTCAGACCGGGATACATTGGACTTGGCGTTACGGAGttcagCAAACGCCTCCGTAAACGCGAGAAATCAAAGAAAGATAAAGAAAATGCGGCGGGTGATGAGAAAGAAAAGGACAAAGATACGACTAAAGAATCGAATGCAGAAGAGGATTGTATTACTATTAGTGATGATGAAGAAGTACGAGAACCTTCAAGATTCATGGCGCAAACGAACATGGGAGCTAGCGAATATATTTCTAAATACAAGTCTGTGCGCACGTTGTTCGGTAAGGACGAGGCGTGCTATATCATGGACGCTAAGGTTCAAGGCAACATTGGCAGATATCTCAATCACTCCTGCTGCCCGAATGTCTTCGTGCAGAACGTGTTCGTGGACACCCACGACCCTCGCTTCCCCTGGGTAGCCTTTTTCGCGCTCTCACACATCAAAGCAGGCACCGAGCTCACCTGGAACTACAACTATGACGTGGGTTCAGTTCCCGGGAAGATACTTTACTGTTATTGTGGAGCTCCTAACTGCAGGGGAAGACTGTTGTAA
Protein Sequence
MSDKEEKNSNDEEKTRINQDEGSKNQKLLTEGNVSLDSSDKNTENIGAIPENVPKGAGDDKARILLDNLELDKIEAELTEMSKEIINTDAGKDAGDYTDKAKVSAIDVKKIEDVNTEVDAKVSKTNFTVKKDESNDTSLGKGNAKESKKADDLDEIEDDDMELRWDDDDDDDASNHAMGDDNGNADTKNDDILSEGQLLDDPSDVLIKDMTETPSDGNPKVSEANLDSDVLKVNSEENSLTRDDNTTEIETTKESEISPKLDIPKDEKILADMCLKENYFTEEINSPEMDFSAENSMDRDDINVLEEKLLQESENTEEINSPEMVFSAEESMDRDDINVLEEKLLEEYEIVNDATVIAPAKDILEEKSMDEPIKETESAKINLLTEVTNDEQTKKDPVAIIEKDKLLAESKSNTEAESSTLNLKSFTDIILNKDNDDIMSEEKLLEEPDSKDESSLIISDKVIECSKIVPEKEAPMNKVDDDDALLEEKLLQETETAEIIPESDITMDVDNEEEGELLKDDECPEDSCTPMDVDNTDTSIGDQAKVEDKIIDQTMNQSEVAKKGIILSIEDQTNIEKVDETTGEVKNMDQSDDQSRIIEKVIDLPIKDTSKAVDIVKDIPMEDEVKIDEEIVDQAVTEKERIDQQMQCSNEDQLILESNAKEQSIKSPVQTDALTVSNTLNILVEDLEKPILEETTLVEEIKLKTDPEEFKENTENKYKDTDLDKPEKNKEIINPDTSFDNNKEVDEILFSNNSSIFLDVSCPIKTDHGVHKPDVMLEIPTQELIDMDDTDLSMNLDHSVMIDGLNDVDKNVDDDIVHDKTIDETVVDDVIGSDKIVTDNATVSEKSVEQANVDEDTVKEKPVDQKALATESTVLDKIIAEDNAEKPVDQKAIDIEMTTVDKMIADEDTVKEKSIVQEAIVTESTVGEVQTVSNIVESDKKVEDTVVQTTVEENMEKLFADDEPEVAKEIAECIASTSQVQVPAEQPSASITRMTPDTSDEIPEIDDSLGLLAESAGRMIEDDEEPDDDFDDDDDFDNDESSNQISAEQSEDSNPAALESELVIDQEDKELETPDPKDEEFMTCDSTSQDKAEKMEVEEQYGTLEFQAETINEMNEEAKSAVDALLNADNPASEQVQDQQETTDQMDIETVKLSDTSDNEVDVEPTEVQQPVAKSSNEEEKQKDSPSKSPSNSNISPKQSPSKSSQSPCKQSPSKMKNLAITMQALSAVVNIVDLEESSSSEDDIQEVQKQQEPEPTQDNTAPSPESDVTNVKIPTGIDIMCTSGGNTSEITTKDNLSQVVISGVPKPPPHKPARLNTSEVSIKTVSNTEPLIIPETKINEQTQTQSKPKLSLEIFSLDSDDDESAAKEKPPTTPPHKMTALELEKARETSKCINYCCTSDNKVPYKLAEASVVAYYDAGRKRRSMVCQPCADVVAARTKNLIQGIKDLTPLLDLDMGKLSQDLVEISDSESEDEVMSTEEPKESIGEKGAKFIEDNLAKYLNETWKKYDMDVRLTETQIMLDDEIEKLEQDSKEIDAMLNECQVATDKLRCELYATFECRRQKLPSLTIYDTPESKTRQAKRRLSSTSETPAKRPAIPLGYAPLDGGDSKEKAAIPAPDNKLDDDKDISVVKLSAEAAPAELPPPGEISRPPLRVGMPVYAMKNAFGPWLKGRVLEIQPRNPSGGNPFSVCLVKFDHKVKTNGKVLPARCIAYSEPADVRMTIGTRLIALFKDSNKRESYYSGVVAEIPNPVNNYRYLVFFDDGYAQYVQHQFTRLVCESSPLVWEEVHPFSREFVRQYLMEYPERPMVRLHEGQHLKTEWNGKWWSSRVTRVDASLAQVMFVGDGRREWIYRGSTRLAPLYLELRAAERHRPRPMPRSKAQPRFNMPYVEYTRSDEQESKKQVDAQAQQPQEQQQQQIQNEEIRRQRAVAKKSTSAPPQVLPPSQQVMPSSLDTVTSRVVYYTPKNAVKPLKMVPHRCGQRCKRSDVLSLKELRTYNPLAKPLLSGWERQIVRFKGHKEVMYRAPCGRRLRNMRELHHYLRTIDSDLPVDLFDFHYSTHCLAEFVLNKCLVGKKDLSHGKENVPVPCVNYYDDSLPEFCSYNTERTPTAGVPLNLEPEFLCGCDCTDDCQDKSKCACWRMTLEGARTIGLRGPNLGYVYKRLPEPLPSGIYECNSRCKCKHTCLNRVAQHPLQLKLQVFKTPNRGWGIRALNDVPKGSFLCVYAGNLLTDATANLDGLNEGDEYLAELDYIEVVEQMKEGYEEDIPEADKKLDKKEGKDGDDSDEDDPSSSEDEETADKTDKEDDDFRPGYIGLGVTEFSKRLRKREKSKKDKENAAGDEKEKDKDTTKESNAEEDCITISDDEEVREPSRFMAQTNMGASEYISKYKSVRTLFGKDEACYIMDAKVQGNIGRYLNHSCCPNVFVQNVFVDTHDPRFPWVAFFALSHIKAGTELTWNYNYDVGSVPGKILYCYCGAPNCRGRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00037842;
90% Identity
iTF_01093126;
80% Identity
-