Basic Information

Insect: Tipula vernalis
Gene Symbol: L
Assembly: GCA_958295665.1
Location: OY282559.1:291547534-291551063[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.51 2.8e+02 5.6 5.7 1 23 3 25 3 25 0.98

2 15 2.1e-07 0.00011 25.7 3.2 1 23 31 53 31 53 0.99

3 15 2.3e-05 0.013 19.2 0.2 1 23 59 81 59 81 0.98

4 15 0.34 1.9e+02 6.1 0.7 2 23 199 221 198 221 0.95

5 15 0.085 47 8.0 0.4 1 23 350 372 350 372 0.95

6 15 0.049 27 8.7 1.1 1 23 380 402 380 402 0.94

7 15 5e-05 0.028 18.1 0.5 1 23 410 434 410 434 0.94

8 15 0.00089 0.5 14.2 0.1 1 23 439 462 439 462 0.97

9 15 0.3 1.6e+02 6.3 1.8 1 23 469 492 469 492 0.96

10 15 0.00029 0.16 15.8 2.2 1 23 524 547 524 548 0.97

11 15 0.00012 0.067 17.0 0.4 2 23 755 777 754 777 0.96

12 15 0.0037 2.1 12.3 0.1 1 23 783 805 783 805 0.98

13 15 0.08 45 8.1 0.3 3 23 945 965 944 965 0.96

14 15 0.00055 0.3 14.9 0.0 1 23 975 997 975 997 0.96

15 15 0.42 2.4e+02 5.8 0.2 1 23 1004 1026 1004 1026 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.51	2.8e+02	5.6	5.7	1	23	3	25	3	25	0.98
2	15	2.1e-07	0.00011	25.7	3.2	1	23	31	53	31	53	0.99
3	15	2.3e-05	0.013	19.2	0.2	1	23	59	81	59	81	0.98
4	15	0.34	1.9e+02	6.1	0.7	2	23	199	221	198	221	0.95
5	15	0.085	47	8.0	0.4	1	23	350	372	350	372	0.95
6	15	0.049	27	8.7	1.1	1	23	380	402	380	402	0.94
7	15	5e-05	0.028	18.1	0.5	1	23	410	434	410	434	0.94
8	15	0.00089	0.5	14.2	0.1	1	23	439	462	439	462	0.97
9	15	0.3	1.6e+02	6.3	1.8	1	23	469	492	469	492	0.96
10	15	0.00029	0.16	15.8	2.2	1	23	524	547	524	548	0.97
11	15	0.00012	0.067	17.0	0.4	2	23	755	777	754	777	0.96
12	15	0.0037	2.1	12.3	0.1	1	23	783	805	783	805	0.98
13	15	0.08	45	8.1	0.3	3	23	945	965	944	965	0.96
14	15	0.00055	0.3	14.9	0.0	1	23	975	997	975	997	0.96
15	15	0.42	2.4e+02	5.8	0.2	1	23	1004	1026	1004	1026	0.95

Sequence Information

Coding Sequence: ATGCCATTCAAATGCGAATATTGCGCCCGACTATTTAAACACAAAAGATCACGTGATCGTCATACAAAATTGCATACGGGCGATCGACGCTATAAATGTCCACATTGTGAGGCGGCATTTTCACGAAGTGATCATCTGAAAATTCATATGAAGACGCATGATAATCAAAAACCATTTCAATGTACGGTTTGTAATCGTGGCTATAATACTGCCGCCGCACTAACATCACACATGCAAAATCATAAGAAACAAGCCGCCCTATTGGCGAATGGCGGAAATGGTGGTAATTTAAGTTACAGTCCACGATCGACTGGTTCGACAGGATCGAGTACATCAAGTTTACATAAGCGGAAATACTCGAATATACCACTCGACCAATTAAATccgcagcaacaacaacagcaaattcATCAGCCGCAACAGAAATTATTGCGTCCAATGATCTCGTgtgtattttgtacaaaatctGATTTTCAAAACGTTGATCAACTAAATCATCATGTCCAGGCGATGCATCACCAGATAACAACCCATGCAACATCGGCTGGTAGTAATCCGGCTAGTTTAGCATCGAGCCCGGTGAATCCAATGATTTCATGTGAATTTTGTACAATGAAATTTGCCTCgattcaacaaatatttcaacactTGAAATCGACGCATATGGATCGGATTAGCAGCCCGAATTCATATTTGGAGCATTTTAATCGTAGCCTAATGTCCACTTACGATATGGGACAGTCGGCAATATCGCCAACTTCGTTATTGTatcgaaataaatttcttcCGGTCGTCAAACAAGAGTCTAAAACACCGGAAATTACTACAGATGTACCAGCAAATCCGATTACATCACCGCCTGTAATTAAACACGAGGCTGAAGATCCGCCAGACCAAGACAGCCCAACCGATTTAAGCCAACCAAAGTCTAAAGTTTTCATCAAAGATGAGAGTAACCAAAGCGCAACAAGCAATAATCATAACGTCAGTAATGGAGATCGTACACCCGAAGCCGTTCCAAAATCCCCCGTTCACCAGGGTggcacatttttatgtaatcaaTGTAATGCGGCTTTGCCAGATTTTGAATCATTCCGTACTCATTTAAAAAGTCACCTCGAGTCGGGAGTTGGAAGCTATTTATGCCAACACTGTGGAATTCCGTTTAACGATCAACAAATTTAtgagaaacatttattttcgcATTTCTTGATGAATGTTACGGAGTATCCGTGCCCGCAAACTTGTAATAAGAATTTCACGAAACAAGAGGACTACCAAAAACATATGATCGATGCTCACATCCAAACCGTATACAGATGTGAAATTTGTACCGAAATTTTCGACACAAAAATCTCAATTCAAGTGCACATGAGCGTTGCCCATGCGAATGAAGTGAAATTGTATCGATGTTCAGCATGTATGGAAGTATACCGAAATGAACGTGATTTCCGCCATCATGTTCGTGCACGCCACATAGTTTCGGGTGCCGTGCAATGCATATTCTGTCGCCAAATATGTTCATCCGAGCTCGATATGCATTTTCATTTGGCTGCACATGCACGACAATTTCGCTGTCCTATCTGTCCCGAATCATTTCACGTCGAATTTTTACTCGATCGGCATATGCAAACGACACATCATCATGGCGTGACGGGTGGTGTTGGTGCGCAAGATCGTCCAAAAGAACCGTACCATCATAAAATTACGGCgaataataatagtaacaacaacaataataataccatTGATTATCATTTGAGCGGAGCGGCAAAACAGGGCCACCACCAGTCGTATCCATTTAatcctaataaattttataatcaacTTCAAATTGATACGCTCGGCGCAAAACATCCAAATTTATTGCATGGATTGTACGATTCGATCAGTAAAAGTCAACGATATCCACCCGACAACGGATTTTTAAGTCCGAATAAAAATTTACTCGGCATCTACAACCATCCCGAAATGATCGCCAAGCTTAACAGTTTTTATagccaaaatgaaaatggtgaaCGATTGTATCCATCGCAACTGCAATCGCACGCACAACAAGCCCCGTCCGCTACGAGTTCAGCGTCACGATATTCGAGCCATGCAGATGCAACTATAAAAAGTCACTTGAGTGGAACATATTCGACGCATCACGGAGATAAAGGTTACAGTTGCGGAATGTGCGAGCGCAATGATTTCAGCACCGAAAATGAAGTACATTCGCATCGAAAACTTGTGCACAATCTCAAAACTGGGGTTAGTCTACGGTGTGCTTATTGTAATGGAGATTTCCGATCACGGAGCGAGTTAGAGAATCACATGAAAGTATCGCATAACACGTCCGGAAAGCATAAATGTCTAATTTGTGATGAAATATTTCCATCGCCTGCCGTATTGGCCGAACACAAATTAACACACTGCAAAGTTGGACCATCCGGACGATGTTCACACTGTCTCATTGAATTGAAAGATGTTACATTCTTTAAGTCACACTTGGCCGAACATAATGGTCACGATATTCCAATTCAATGTATATGCTGCCGCCAGACGCTAAACTCTGAGTTTGAAATTGGATTGCACGCGAAATTTCATACCAAATCGAGCGAGGTCAAAGAGAATACGTGTGCATTATGTCTCGAGACGTTGCCGCCTAACGTTGAGACTCGCGTATGCGAATCATGCTAcaagaaacataatttaaatttaaaaacaaatattttacagcaacataataatagtagtattagtagtaataataataataataataatggtagcagtagtaataacaataatagtaatagagataatttaaatattaaccaaGAAGTGTTATGTAACCTGTGTAAGAAAACTTTGGCGAACCAAATCCGGCTGCAGGAGCATTTGATCGAACATACATTTGCTGGTTGTGAAGATCGCGGTTACATATGCTATATATGTTCGGCAGTATTTACATCACCGACCGGATTACAATCGCATATCATCGAACACGGTTTAAATGCACGACCGTACGATTGTAATTTATGCCCGGCTAAATATTTCTTCCGAGCTGAATTAGACAATCATACGATTGAGCACGATAACAATAATATCGTCCAGAATAAATCAAACAATGTACCAATACCACCTGTATCCAATCATATGAGCGTTGTACAaccagaaaatttgaaaaaagaaataacCGCAGCCGAAGAAAATCATACGGATGAGGAGGATATAAAACATCAACCTGATGAAGAGGAAGAATATATTGAGGTTGAAAATTTGGAGACAAACCACGAGAATAAACTCgataacaaataa
Protein Sequence: MPFKCEYCARLFKHKRSRDRHTKLHTGDRRYKCPHCEAAFSRSDHLKIHMKTHDNQKPFQCTVCNRGYNTAAALTSHMQNHKKQAALLANGGNGGNLSYSPRSTGSTGSSTSSLHKRKYSNIPLDQLNPQQQQQQIHQPQQKLLRPMISCVFCTKSDFQNVDQLNHHVQAMHHQITTHATSAGSNPASLASSPVNPMISCEFCTMKFASIQQIFQHLKSTHMDRISSPNSYLEHFNRSLMSTYDMGQSAISPTSLLYRNKFLPVVKQESKTPEITTDVPANPITSPPVIKHEAEDPPDQDSPTDLSQPKSKVFIKDESNQSATSNNHNVSNGDRTPEAVPKSPVHQGGTFLCNQCNAALPDFESFRTHLKSHLESGVGSYLCQHCGIPFNDQQIYEKHLFSHFLMNVTEYPCPQTCNKNFTKQEDYQKHMIDAHIQTVYRCEICTEIFDTKISIQVHMSVAHANEVKLYRCSACMEVYRNERDFRHHVRARHIVSGAVQCIFCRQICSSELDMHFHLAAHARQFRCPICPESFHVEFLLDRHMQTTHHHGVTGGVGAQDRPKEPYHHKITANNNSNNNNNNTIDYHLSGAAKQGHHQSYPFNPNKFYNQLQIDTLGAKHPNLLHGLYDSISKSQRYPPDNGFLSPNKNLLGIYNHPEMIAKLNSFYSQNENGERLYPSQLQSHAQQAPSATSSASRYSSHADATIKSHLSGTYSTHHGDKGYSCGMCERNDFSTENEVHSHRKLVHNLKTGVSLRCAYCNGDFRSRSELENHMKVSHNTSGKHKCLICDEIFPSPAVLAEHKLTHCKVGPSGRCSHCLIELKDVTFFKSHLAEHNGHDIPIQCICCRQTLNSEFEIGLHAKFHTKSSEVKENTCALCLETLPPNVETRVCESCYKKHNLNLKTNILQQHNNSSISSNNNNNNNGSSSNNNNSNRDNLNINQEVLCNLCKKTLANQIRLQEHLIEHTFAGCEDRGYICYICSAVFTSPTGLQSHIIEHGLNARPYDCNLCPAKYFFRAELDNHTIEHDNNNIVQNKSNNVPIPPVSNHMSVVQPENLKKEITAAEENHTDEEDIKHQPDEEEEYIEVENLETNHENKLDNK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01456739; iTF_01457814; iTF_01458906; iTF_01054654; iTF_01052560; iTF_01053723;
90% Identity: iTF_01456739;
80% Identity: -