Basic Information

Insect: Nephrotoma flavescens
Gene Symbol: L
Assembly: GCA_932525705.1
Location: CAKOBH010002247.1:190041-193704[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.5 90 5.5 5.7 1 23 3 25 3 25 0.98

2 15 2e-07 3.7e-05 25.7 3.2 1 23 31 53 31 53 0.99

3 15 2.3e-05 0.0041 19.2 0.2 1 23 59 81 59 81 0.98

4 15 0.17 30 7.0 0.9 2 23 199 221 198 221 0.96

5 15 0.22 40 6.6 0.4 1 23 351 373 351 373 0.95

6 15 0.048 8.7 8.7 1.1 1 23 381 403 381 403 0.94

7 15 3.4e-05 0.0062 18.6 0.5 1 23 411 435 411 435 0.94

8 15 0.0043 0.78 12.0 0.0 1 23 440 463 440 463 0.97

9 15 0.29 53 6.3 1.8 1 23 470 493 470 493 0.96

10 15 0.00023 0.041 16.1 1.4 1 23 525 548 525 549 0.97

11 15 0.00012 0.021 16.9 0.4 2 23 752 774 751 774 0.96

12 15 0.0037 0.66 12.3 0.1 1 23 780 802 780 802 0.98

13 15 0.081 15 8.0 0.2 3 23 945 965 944 965 0.96

14 15 0.00036 0.065 15.4 0.1 1 23 975 997 975 997 0.96

15 15 0.42 76 5.8 0.2 1 23 1004 1026 1004 1026 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.5	90	5.5	5.7	1	23	3	25	3	25	0.98
2	15	2e-07	3.7e-05	25.7	3.2	1	23	31	53	31	53	0.99
3	15	2.3e-05	0.0041	19.2	0.2	1	23	59	81	59	81	0.98
4	15	0.17	30	7.0	0.9	2	23	199	221	198	221	0.96
5	15	0.22	40	6.6	0.4	1	23	351	373	351	373	0.95
6	15	0.048	8.7	8.7	1.1	1	23	381	403	381	403	0.94
7	15	3.4e-05	0.0062	18.6	0.5	1	23	411	435	411	435	0.94
8	15	0.0043	0.78	12.0	0.0	1	23	440	463	440	463	0.97
9	15	0.29	53	6.3	1.8	1	23	470	493	470	493	0.96
10	15	0.00023	0.041	16.1	1.4	1	23	525	548	525	549	0.97
11	15	0.00012	0.021	16.9	0.4	2	23	752	774	751	774	0.96
12	15	0.0037	0.66	12.3	0.1	1	23	780	802	780	802	0.98
13	15	0.081	15	8.0	0.2	3	23	945	965	944	965	0.96
14	15	0.00036	0.065	15.4	0.1	1	23	975	997	975	997	0.96
15	15	0.42	76	5.8	0.2	1	23	1004	1026	1004	1026	0.95

Sequence Information

Coding Sequence: ATGCCATTCAAATGCGAATACTGTGCCCGTCTATTTAAACACAAACGATCACGTGATCGTCATACAAAATTGCATACGGGTGATCGACGCTATAAATGTCCACATTGTGAGGCGGCATTTTCACGAAGCGATCATCTTAAAATTCATATGAAGACGCATGATAATCAGAAACCATTCCAATGCACGGTTTGTAATCGAGGTTATAATACTGCCGCGGCACTTACATCGCACATGCAAAATCATAAAAAGCAGGCCGCCCTACTTGCGAACGGTGGAAATGGCGGTAATTTAAATTATAGTCCACGATCAACTGGATCAACCGGATCGAGTACGTCAAGTTTACATAAGCGAAAATACTCGAATATACCACTCGATCAATTAAATCCGCAGCAGCAGCAACAGCAAATACATCAGCCGCACCAGAAATTGTCCCGATCGATGATCTCGTGCGTATTTTGTACGAAATCGGATTTTCAAAATGTCGATCAACTAAATCATCATGTGCAGGCAATGCATCATCAGACAGCGACTCAAATACCATCGGGTGGCAGTAATCCTGCTAGTCTAACATCGAGTCCAGTCAATCCTATGATCTCGTGCGAATTTTGTACAATGAAATTTGTCTCGATTCAGCAAATATTTCAACATTTAAAAACTACGCATATGGATCGGATTAGTAGCCCAAATTCATATTTGGAACATTTTAATCGTAATTTAATGTCGACCTATGATATGGCACAGTCGGCCTTATCACCGAGCTCCTTACTGTATCGCAACAAGTTTCTTCCGGTGGTAAAGCAAGAGTCAAAAACACCGGATATTCCATCTGAAGCACCACCAAATTCGATTACATCGCCACCTGTAATAAAACACGAGGCTGAAGATCCGCCGGACCAGGAAAGTCCGACCGATTTAAGCCAACCGAAATCTAAAGTGTTCATCAAAGACGAAAGCAATCACAGTGCAACCAGCAATAACAACAATAATGCGAGTAACGGTGATCGTACACCCGAAACCATCCAAAAATCTCCGGTTCACCAGAATGGCACATTTTTATGTAATCAATGTAGCGCAGCCCTGCCAGATTTTGAATCGTTCCGTACGCATCTAAAAAGTCATCTCGAATCGGGAGTTGGCAGCTATTTGTGCCAACACTGTGGCATCCCGTTTAATGATCAACAAATTTACGAGAAACATTTATTTTCACACTTTTTGATGAACGTAACAGAATATCCGTGTCCGCAAACGTGCAACAAAAATTTCACGAAACAAGAGGATTTCCAAAAACATATGATTGATGCGCACATCCAGACCGTGTACCGTTGTGAAATTTGTGCTGAAATTTTCGATACAAAAATTTCAATTCAAGTGCACATGAGCGTTGCCCATCCGAACGAAGTGAAATTGTATAGATGCTCGGCCTGCATGGAAGTGTATCGAAATGAGCGCGATTTTCGGCATCATGTTCGCGCACGCCACATAGTTTCGGGCGCCGTTCAATGCATATTCTGCCGCCAAATATGTTCGTCCGAGCTCGATATGCATTTCCATTTGGCTGCACATGCTCGACAATATCGATGTCCGGTGTGTCCCGAATCGTTTCATGTTGAATTCTTGCTTGATCGACATATGCAAACAGTTCATCATCATGGTGTGGGCAGCGGTGGTGCACAAGATCGTCCGAAAGAGCCATATCATCATAAAATTACAAATAATAATAACAACAACAACACTCTTGATTATCATTTGGGCGGGGCAGCTAAACCAATGGGTCACCACCAATCGTATCCATTTAATACGAATAAATTTTATAACCAGCTTCAAATTGATACGCTCAGCGCAAAACATCCAAACTTATTGCATGGGCTGTACGATTCGATCAGTAAAAGTCAACGATATCCACCCGACAATGGATTTTTGAGCCCCAATAAAAATTTGCTTGGCATTTACAATCATCCCGAAATGATTGCAAAACTTAACAGTTTTTACAATCAGGCCGAAAATGGAGAGCGATTATATCCACCGCAACTGCAATCGCACTCGCAACAAGCTCCATCCGCTACTAGTTCGGCGTCCCGATATCCTAGTCACTCGGACGCCACTATAAAAAGCCATTTGAGCGGAACTTATTCGACGCATCACGGCGAGAAAGGTTATAGTTGTGGAATGTGTGAGCGCAATGATTTCAGCACCGAAAATGAAGTGCACTCGCACCGAAAGCTTGTACACAATCTTAAAACGGGTGTAAGTCTTAGATGTGCCTACTGTAACGGGGACTTCAGATCACGGAGCGAACTAGAGAATCATATGAAAGTGTCACATAATACGTCAGGCAAACATAAATGTTTAATTTGTGATGAGATTTTCCCATCGCCGGCCGTTTTGGCCGAACACAAATTAACTCACTGTAAAGTTGGGCCGTCCGGGAGGTGTTCACATTGCCTCATCGAATTGAAAGATGTGACATTCTTCAAGTCACATTTGGCCGAGCATAACGGACATGATATACCGATACAATGTATATGTTGTCGCCAGACGCTTAATTCGGAGTTCGAAATCGGATTGCACGCCAAATTTCATACGAAGACGAGTGAGGTGAAAGAAAATACGTGCGCACTATGCCTTGAGACATTACCGCCTAATGTTGAAACACGTGTATGCGAATCATGCTACAAGAAACATAATTTAAATTTAAAGACAAATATTTTACAACAACATACTAGTAGTAGTGTTAGTAATACCAATAATAATAATAATAATAATGGTAGTAGTAGTAGTAGTAGTGCTAATAATTGTAATAGAGATAGTTTAAATATTAACCAAGAAGCATTTTGTAACCTATGCAAGAAAACATTAGCAAATCCGATTCGACTGCAAGAACATTTAATCGAGCATACATTCGCCGGGTGCGATGATCGTGGCTACATATGCTATATATGCTCATCGGTATTTACATCGCCTAGTGGTTTACAATCGCACATCATCGAACACGGATTAAACGCTCGACCGTATGATTGTAATTTATGTCCGGCGAAATATTTCTTCCGCGCTGAATTAGATAATCATACGATTGAACACGAGAATAATAATGTCGCACCAAATAAATCGGGTAACGTATTAATACCACCACCACTACCACCACAACCACCACTGCCACCTGCCGGACCATCCAACCATATCGGTGAACAACCAGAAAATCTAAAAAAAGAAATGAATACGGTGACGGAAGAAAATCGCTGCCCCGACGAGGAAGATGTAAAACATCATCCCGATGAGGAGGAGGAATATATCGAGGTGGAAAATTTGGAGGCAAGCCACGAGAATAAACTCGATAACAAATAA
Protein Sequence: MPFKCEYCARLFKHKRSRDRHTKLHTGDRRYKCPHCEAAFSRSDHLKIHMKTHDNQKPFQCTVCNRGYNTAAALTSHMQNHKKQAALLANGGNGGNLNYSPRSTGSTGSSTSSLHKRKYSNIPLDQLNPQQQQQQIHQPHQKLSRSMISCVFCTKSDFQNVDQLNHHVQAMHHQTATQIPSGGSNPASLTSSPVNPMISCEFCTMKFVSIQQIFQHLKTTHMDRISSPNSYLEHFNRNLMSTYDMAQSALSPSSLLYRNKFLPVVKQESKTPDIPSEAPPNSITSPPVIKHEAEDPPDQESPTDLSQPKSKVFIKDESNHSATSNNNNNASNGDRTPETIQKSPVHQNGTFLCNQCSAALPDFESFRTHLKSHLESGVGSYLCQHCGIPFNDQQIYEKHLFSHFLMNVTEYPCPQTCNKNFTKQEDFQKHMIDAHIQTVYRCEICAEIFDTKISIQVHMSVAHPNEVKLYRCSACMEVYRNERDFRHHVRARHIVSGAVQCIFCRQICSSELDMHFHLAAHARQYRCPVCPESFHVEFLLDRHMQTVHHHGVGSGGAQDRPKEPYHHKITNNNNNNNTLDYHLGGAAKPMGHHQSYPFNTNKFYNQLQIDTLSAKHPNLLHGLYDSISKSQRYPPDNGFLSPNKNLLGIYNHPEMIAKLNSFYNQAENGERLYPPQLQSHSQQAPSATSSASRYPSHSDATIKSHLSGTYSTHHGEKGYSCGMCERNDFSTENEVHSHRKLVHNLKTGVSLRCAYCNGDFRSRSELENHMKVSHNTSGKHKCLICDEIFPSPAVLAEHKLTHCKVGPSGRCSHCLIELKDVTFFKSHLAEHNGHDIPIQCICCRQTLNSEFEIGLHAKFHTKTSEVKENTCALCLETLPPNVETRVCESCYKKHNLNLKTNILQQHTSSSVSNTNNNNNNNGSSSSSSANNCNRDSLNINQEAFCNLCKKTLANPIRLQEHLIEHTFAGCDDRGYICYICSSVFTSPSGLQSHIIEHGLNARPYDCNLCPAKYFFRAELDNHTIEHENNNVAPNKSGNVLIPPPLPPQPPLPPAGPSNHIGEQPENLKKEMNTVTEENRCPDEEDVKHHPDEEEEYIEVENLEASHENKLDNK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01460553;
90% Identity: iTF_01052560;
80% Identity: -