Basic Information

Insect: Nephrotoma appendiculata
Gene Symbol: L
Assembly: GCA_947310385.1
Location: OX371223.1:85598380-85602034[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.53 1.2e+02 5.5 5.7 1 23 3 25 3 25 0.98

2 15 2.2e-07 4.8e-05 25.7 3.2 1 23 31 53 31 53 0.99

3 15 2.4e-05 0.0053 19.2 0.2 1 23 59 81 59 81 0.98

4 15 0.22 49 6.7 0.9 2 23 199 221 198 221 0.96

5 15 0.24 52 6.6 0.4 1 23 351 373 351 373 0.95

6 15 0.052 11 8.7 1.1 1 23 381 403 381 403 0.94

7 15 5.3e-05 0.012 18.1 0.5 1 23 411 435 411 435 0.94

8 15 0.0046 1 12.0 0.0 1 23 440 463 440 463 0.97

9 15 0.45 99 5.8 1.9 1 23 470 493 470 493 0.96

10 15 0.00024 0.053 16.1 1.4 1 23 525 548 525 549 0.97

11 15 0.00013 0.028 16.9 0.4 2 23 752 774 751 774 0.96

12 15 0.0039 0.87 12.3 0.1 1 23 780 802 780 802 0.98

13 15 0.058 13 8.6 0.2 2 23 943 964 943 964 0.95

14 15 0.00038 0.085 15.4 0.1 1 23 974 996 974 996 0.96

15 15 0.45 99 5.8 0.2 1 23 1003 1025 1003 1025 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.53	1.2e+02	5.5	5.7	1	23	3	25	3	25	0.98
2	15	2.2e-07	4.8e-05	25.7	3.2	1	23	31	53	31	53	0.99
3	15	2.4e-05	0.0053	19.2	0.2	1	23	59	81	59	81	0.98
4	15	0.22	49	6.7	0.9	2	23	199	221	198	221	0.96
5	15	0.24	52	6.6	0.4	1	23	351	373	351	373	0.95
6	15	0.052	11	8.7	1.1	1	23	381	403	381	403	0.94
7	15	5.3e-05	0.012	18.1	0.5	1	23	411	435	411	435	0.94
8	15	0.0046	1	12.0	0.0	1	23	440	463	440	463	0.97
9	15	0.45	99	5.8	1.9	1	23	470	493	470	493	0.96
10	15	0.00024	0.053	16.1	1.4	1	23	525	548	525	549	0.97
11	15	0.00013	0.028	16.9	0.4	2	23	752	774	751	774	0.96
12	15	0.0039	0.87	12.3	0.1	1	23	780	802	780	802	0.98
13	15	0.058	13	8.6	0.2	2	23	943	964	943	964	0.95
14	15	0.00038	0.085	15.4	0.1	1	23	974	996	974	996	0.96
15	15	0.45	99	5.8	0.2	1	23	1003	1025	1003	1025	0.95

Sequence Information

Coding Sequence: ATGCCATTCAAATGCGAATACTGTGCCCGGCTATTTAAACACAAGCGATCACGTGATCGTCATACAAAGTTGCATACGGGTGATCGACGCTATAAATGTCCACATTGTGAGGCGGCGTTTTCACGAAGCGATCATCTTAAAATTCATATGAAGACGCATGATAATCAAAAACCATTCCAATGTACGGTTTGTAATCGAGGTTATAATACTGCCGCGGCGCTTACATCGCACATGCAAAATCACAAAAAGCAAGCGGCCCTACTAGCGAACGGTGGAAACGGTGGCAATTTAAATTATAGTCCACGATCAACGGGATCGACCGGATCGAGTACGTCAAGTTTACATAAGCGAAAATACTCGAATATACCACTCGATCAGTTAAATCCGCAGCAGCAGCAACAGCAAATACATCAGCCGCACCAGAAATTGTCCCGATCGATGATCTCATGCGTATTTTGTACGAAATCGGATTTTCAAAATGTCGATCAACTAAATCATCATGTGCAGGCAATGCATCACCAGACAACGTCTCAAACACCATCGGGTGGCAGTAATCCTGCTAGTCTAACATCGAGTCCAGTCAATCCTATGATCTCGTGTGAATTTTGTACAATGAAATTTATCTCGATTCAACAAATATTTCAGCATTTAAAAACTACGCATATGGATCGGATTAGCAGCCCAAATTCATATTTGGAACATTTTAATCGTAATTTAATGTCAACCTACGATATGGCACAGTCGGCCTTATCACCGAGCTCCTTACTGTATCGCAACAAGTTTCTTCCGGTGGTAAAGCAAGAATCCAAAACCCCTGATATCCCATCTGAAGCACCGGCAACTTCGATTACGTCGCCACCTGTAATTAAACACGAGGCTGAAGATCCGCCGGATCAGGAAAGTCCGACCGATTTAAGCCAACCGAAATCTAAAGTTTTCATCAAAGATGAAAGCAATCACAGTGCAACCAGCAATAACAACAATAATGCGAGTAACGGTGATCGTACACCCGAAACCATCCAAAAATCACCGATTCACCAGAATGGCACATTTCTATGTAATCAATGTAGCGCAGCCTTGCCAGATTTTGAATCGTTCCGTACGCACCTAAAAAGTCATCTCGAATCGGGAGTTGGCAGCTATTTGTGCCAACATTGTGGCATCCCGTTTAATGATCAACAAATTTACGAGAAGCATTTATTTTCACACTTTTTGATGAACGTAACAGAATATCCGTGTCCGCAAACGTGCAACAAAAATTTCACGAAACAAGAGGATTACCAAAAACATATGATTGATGCTCACATCCAGACGGTGTACCGTTGTGAAATTTGTGCTGAAATTTTCGATACAAAAATTTCCATTCAAGTGCACATGAGTGTTGCCCATCCGAACGAAGTGAAATTGTTTAGGTGTTCGGCCTGCATGGAAGTGTATCGAAATGAGCGCGATTTTCGGCATCATGTTCGTGCACGCCACATAGTTTCGGGCGCCGTACAATGCATATTCTGCCGCCAAATATGTTCGTCCGAGCTCGATATGCATTTCCATTTGGCTGCGCATGCTCGACAATATCGGTGTCCGGTGTGTCCCGAATCGTTTCATGTTGAATTCTTGCTTGATCGACATATGCAAACGGTTCATCATCATGGTGTGGGAGGCGGTGGTGCACAAGATCGTCCGAAAGAGCCATATCATCATAAAATTACAAATAATAATAACAACAACAACACTATTGATTATCATTTGGGCGGGGTAGCTAAACCGGGTCACCACCAATCGTATCCATTTAATACGAATAAATTTTATAACCAGCTTCAAATTGATACGCTCAGCGCAAAACATCCAAATTTATTGCATGGGCTGTATGACTCGATCAGTAAAAGTCAACGATATCCACCCGATAATGGATTTTTGAGCCCCAATAAAAATTTGCTTGGTATTTACAACCATCCCGAAATGATTGCAAAACTTAACAGTTTTTATAATCAGGCGGAAAATGGGGAGCGATTATATCCACCGCAACTGCAATCGCACTCGCAACAAGCTCAATCCGCTGCTGCTAGTTCAGCGTCCCGGTATTCTAGTCACACGGACGCCACACTAAAAAGTCATTTGAGTGGAACTTATTCGACGCATCACGGCGAGAAAGGCTATAGTTGCGGAATGTGTGAGCGCAATGATTTCAGCACCGAAAATGAAGTGCACTCGCACCGAAAGCTTGTACACAATCTTAAAACCGGTGTAAGTCTTAGATGTGCCTATTGTAACGGGGACTTCAGATCACGGAGCGAACTAGAGAATCACATGAAAGTGTCACATAATACGTCAGGCAAACATAAATGTTTAATTTGTGATGAGATTTTCCCATCGCCGGCCGTTTTGGCCGAACACAAATTAACCCACTGCAAAGTTGGACCGTCCGGGAGGTGTTCCCATTGCCTCATCGAATTGAAAGATGTGACATTCTTCAAGTCACATTTGGCCGAGCATAACGGTCATGATATACCGATACAATGTATATGTTGTCGCCAGACGCTTAATTCAGAGTTCGAAATCGGACTGCACGCCAAATTTCACACGAAGACGAGTGAGGTGAAAGAAAATACGTGCGCACTATGCCTCGAGACGTTGCCGCCTAATGTTGAAACGCGTGTATGCGAATCATGCTACAAGAAACATAATTTAAATTTAAAAACAAATATTTTACAACAACATACTAGTAGTAGTGTTAGTAATACCAATAATAATAATAATAATGGTAGTAGTAGTAGTAGTAGTGCTAATAATTGTAATAGAGATAGTTTAAATATTAACCAAGAAGCATATTGTAACCTATGCAAGAAAACATTAGCAAATCCGATTCGGCTGCAAGAACATTTAATCGAGCATACATTCGCCGGTTGCGATGATCGTGGCTACATATGTTACATATGCTCATCGGTATTTACATCGCCTAGCGGTTTACAATCGCACATCATCGAACACGGGTTAAACGCTCGACCGTATGATTGTAATTTATGTCCGGCGAAATATTTCTTCCGCGCTGAATTAGATAATCATACGATTGAACACGAGAATAATAATGTCGCACCAAATAAGTCGGTTAACGTATTAATACCACCGCCACCACCACCACCACCACTGCCACCTACCGGACCATCCAATCATATCGGTGAACAACCAGAAAATCTAAAAAAAGAAATGAATACGGTGACGGAAGAAAATCGCTGCCCCGTCGAGGAAGATGTAAAACATCATCCCGATGAGGAGGAGGAATATATCGAGGTGGAAAATTTGGAGACAAGCCACGAGAATAATAAACTCGATAACAAATAA
Protein Sequence: MPFKCEYCARLFKHKRSRDRHTKLHTGDRRYKCPHCEAAFSRSDHLKIHMKTHDNQKPFQCTVCNRGYNTAAALTSHMQNHKKQAALLANGGNGGNLNYSPRSTGSTGSSTSSLHKRKYSNIPLDQLNPQQQQQQIHQPHQKLSRSMISCVFCTKSDFQNVDQLNHHVQAMHHQTTSQTPSGGSNPASLTSSPVNPMISCEFCTMKFISIQQIFQHLKTTHMDRISSPNSYLEHFNRNLMSTYDMAQSALSPSSLLYRNKFLPVVKQESKTPDIPSEAPATSITSPPVIKHEAEDPPDQESPTDLSQPKSKVFIKDESNHSATSNNNNNASNGDRTPETIQKSPIHQNGTFLCNQCSAALPDFESFRTHLKSHLESGVGSYLCQHCGIPFNDQQIYEKHLFSHFLMNVTEYPCPQTCNKNFTKQEDYQKHMIDAHIQTVYRCEICAEIFDTKISIQVHMSVAHPNEVKLFRCSACMEVYRNERDFRHHVRARHIVSGAVQCIFCRQICSSELDMHFHLAAHARQYRCPVCPESFHVEFLLDRHMQTVHHHGVGGGGAQDRPKEPYHHKITNNNNNNNTIDYHLGGVAKPGHHQSYPFNTNKFYNQLQIDTLSAKHPNLLHGLYDSISKSQRYPPDNGFLSPNKNLLGIYNHPEMIAKLNSFYNQAENGERLYPPQLQSHSQQAQSAAASSASRYSSHTDATLKSHLSGTYSTHHGEKGYSCGMCERNDFSTENEVHSHRKLVHNLKTGVSLRCAYCNGDFRSRSELENHMKVSHNTSGKHKCLICDEIFPSPAVLAEHKLTHCKVGPSGRCSHCLIELKDVTFFKSHLAEHNGHDIPIQCICCRQTLNSEFEIGLHAKFHTKTSEVKENTCALCLETLPPNVETRVCESCYKKHNLNLKTNILQQHTSSSVSNTNNNNNNGSSSSSSANNCNRDSLNINQEAYCNLCKKTLANPIRLQEHLIEHTFAGCDDRGYICYICSSVFTSPSGLQSHIIEHGLNARPYDCNLCPAKYFFRAELDNHTIEHENNNVAPNKSVNVLIPPPPPPPPLPPTGPSNHIGEQPENLKKEMNTVTEENRCPVEEDVKHHPDEEEEYIEVENLETSHENNKLDNK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01460553;
90% Identity: iTF_01053723; iTF_01054654;
80% Identity: -