Basic Information

Insect: Nephrotoma guestfalica
Gene Symbol: L
Assembly: GCA_963691935.1
Location: OY829914.1:236093402-236097024[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.49 97 5.5 5.7 1 23 3 25 3 25 0.98

2 15 2e-07 3.9e-05 25.7 3.2 1 23 31 53 31 53 0.99

3 15 2.2e-05 0.0044 19.2 0.2 1 23 59 81 59 81 0.98

4 15 0.16 32 7.1 0.9 2 23 199 221 198 221 0.96

5 15 0.083 16 8.0 0.4 1 23 351 373 351 373 0.95

6 15 0.048 9.4 8.7 1.1 1 23 381 403 381 403 0.94

7 15 3.4e-05 0.0066 18.6 0.5 1 23 411 435 411 435 0.94

8 15 0.0043 0.84 12.0 0.0 1 23 440 463 440 463 0.97

9 15 0.41 81 5.8 1.9 1 23 470 493 470 493 0.96

10 15 0.00022 0.044 16.1 1.4 1 23 525 548 525 549 0.97

11 15 0.00012 0.023 16.9 0.4 2 23 751 773 750 773 0.96

12 15 0.0036 0.71 12.3 0.1 1 23 779 801 779 801 0.98

13 15 0.054 11 8.6 0.2 2 23 942 963 942 963 0.95

14 15 0.00035 0.069 15.4 0.1 1 23 973 995 973 995 0.96

15 15 0.41 81 5.8 0.2 1 23 1002 1024 1002 1024 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.49	97	5.5	5.7	1	23	3	25	3	25	0.98
2	15	2e-07	3.9e-05	25.7	3.2	1	23	31	53	31	53	0.99
3	15	2.2e-05	0.0044	19.2	0.2	1	23	59	81	59	81	0.98
4	15	0.16	32	7.1	0.9	2	23	199	221	198	221	0.96
5	15	0.083	16	8.0	0.4	1	23	351	373	351	373	0.95
6	15	0.048	9.4	8.7	1.1	1	23	381	403	381	403	0.94
7	15	3.4e-05	0.0066	18.6	0.5	1	23	411	435	411	435	0.94
8	15	0.0043	0.84	12.0	0.0	1	23	440	463	440	463	0.97
9	15	0.41	81	5.8	1.9	1	23	470	493	470	493	0.96
10	15	0.00022	0.044	16.1	1.4	1	23	525	548	525	549	0.97
11	15	0.00012	0.023	16.9	0.4	2	23	751	773	750	773	0.96
12	15	0.0036	0.71	12.3	0.1	1	23	779	801	779	801	0.98
13	15	0.054	11	8.6	0.2	2	23	942	963	942	963	0.95
14	15	0.00035	0.069	15.4	0.1	1	23	973	995	973	995	0.96
15	15	0.41	81	5.8	0.2	1	23	1002	1024	1002	1024	0.95

Sequence Information

Coding Sequence: ATGCCATTCAAATGCGAATACTGTGCCCGGCTATTTAAACACAAACGATCACGTGATCGTCATACAAAATTGCATACGGGTGATCGACGCTATAAATGTCCACATTGTGAGGCGGCATTTTCACGaagcGATCATCTTAAAATTCATATGAAGACGCATGATAATCAGAAACCATTCCAATGTACGGTTTGTAATCGAGGTTACAATACCGCCGCGGCGCTTACATCGCACatgcaaaatcataaaaagCAGGCCGCCCTACTAGCGAACGGGGGAAACGGTggcaatttaaattatagtcCACGATCAACCGGATCAACCGGATCGAGTACGTCAAGTTTACATAAGCGAAAATACTCGAATATACCACTCGATCAGTTAAATCCgcagcagcagcaacagcaaATACATCAGCCGCATCAGAAATTGTCCCGATCGATGATCTCGTGTGTTTTTTGTACGAAATCGGATTTTCAAAATGTCGATCAACTAAATCATCACGTGCAGGCAATGCATCACCAGACAGCGGCTCAAACACCATCGGGTGGCAGTAATCCCGCTAGTCTAACGTCAAGTCCGGTCAATCCTATGATCTCGTGTGAATTTTGTACAATGAAATTTGTCTCGattcaacaaatatttcaacatttaaaaaCTACGCATATGGATCGGATTAGTAGCCCAAATTCATATTTGGAACATTTTAATCGTAATTTAATGTCGACTTATGATATGGCACAGTCGGCCTTATCGCCGAGCTCTTTACTGTATCGCAACAAGTTTCTTCCGGTGGTAAAGCAAGAATCAAAAACACCGGATATTCCAACTGAAGCGCCAACAAATTCGATTACATCGCCACCTGTAATTAAACACGAGGCTGAAGATCCCCCGGATCAGGAAAGTCCGACCGATTTAAGCCAACCGAAATCTAAAGTTTTCATCAAGGACGAAAGTAATCACAGCGCAAccagcaataacaacaacaatgcgaGTAACGGAGATCGTACACCCGAAACCATCCAAAAGTCCCCGATTCACCAGAGCGGCACATTTTTATGTAATCAATGTAACGCAGCCTTGCCAGATTTTGAATCGTTCCGTACGCATCTAAAAAGCCATCTCGAATCGGGAGTTGGCAGCTATTTGTGCCAGCACTGTGGCATCCCGTTTAATGATCAACAAATTTACgagaaacatttattttcacaCTTTTTGATGAACGTAACAGAATATCCGTGTCCGCAAACgtgcaacaaaaatttcacgAAACAAGAGGATTTCCAAAAACACATGATTGATGCACACATCCAGACCGTGTACCGTTGTGAAATTTGTGCCGAAATTTtcgatacaaaaatttcaattcaagtGCACATGAGCGTTGCCCATCCGAATGAAGTGAAATTGTTTAGGTGCTCGGCCTGCATGGAAGTGTATCGAAATGAGCGTGATTTTCGACATCATGTTCGCGCACGCCACATAGTTTCGGGCGCCGTTCAATGTATATTCTGCCGTCAAATATGTTCATCTGAGCTCGATATGCATTTCCATTTGGCTGCGCATGCTCGACAATATCGATGTCCCGTGTGTCCCGAATCGTTCCACGTTGAATTCTTGCTTGATCGACATATGCAAACGGTTCATCATCATGGTGTGGGAAGCGGTGGTGCACAAGATCGTCCGAAAGAGCCATATCatcataaaattacaaataataacaataacaacaacactaTTGATTATCATTTGGGTGGGGTAGCTAAACCGGGTCACCACCAATCGTATccatttaatacaaataaattttataaccagcTTCAAATTGATACGCTTAACGCAAAACATCCAAATTTATTGCACGGGCTGTACGACTCAATCAGTAAAAGTCAACGATATCCACCCGATAATGGATTTTTGAGCCCCAATAAAAATTTGCTTGGTATCTACAACCATCCCgaaatgattgcaaaattaaacagtttttaCAACCAGACCGAAAATGGGGATCGATTATATCCACCGCAACTGCAGTCGCACTCGCAACAAGCTCCATCCGCTACTAGTTCGGCGTCCCGGTATCCTAGTCACACAGACGCCACTATAAAAAGTCATTTGAGTGGAACTTATTCGACGCATCACGGCGAGAAAGGTTATAGTTGCGGAATGTGTGAGCGCAATGATTTCAGCACCGAAAATGAAGTGCACTCGCACCGAAAGCTTGTACATAATCTTAAAACCGGTGTAAGTCTTAGGTGTGCTTACTGTAACGGGGACTTCAGATCACGGAGCGAACTAGAGAACCACATGAAAGTATCACATAATACGTCAGGCAAGCATAAATGTCTAATTTGTGATGAGATTTTCCCATCGCCGGCCGTTTTGGCCGAACACAAATTAACCCACTGCAAAGTTGGACCGTCCGGAAGGTGTTCACATTGCCTCATCGAATTGAAAGATGTGACGTTCTTCAAGTCTCATTTGGCCGAGCATAATGGTCATGATATACCGATACAATGTATATGTTGTCGCCAGACGCTTAATTCGGAGTTCGAAATCGGATTGCACGCCAAATTTCATACAAAGACGAGCGAGGTCAAAGAAAATACGTGCGCATTATGCCTCGAGACGTTACCGCCTAATGTTGAAACACGTGTGTGCGAATCATGCTACAAgaaacacaatttaaatttaaaaacaaatattttacaacaacatACTAGTAGTAGTGTTAGtaataccaataataataataacaatggtagtagtagtagtagtagtgcTAATAATTGTAATAGAGATAGTTTAAATATTAACCAAGAAGCATATTGTAACCTATGCAAGAAAACGTTAGCAAACCCGATTCGCCTGCAAGAACATTTAATCGAGCATACATTCGCCGGTTGTGATGATCGTGGCTACATATGCTACATATGCTCATCGGTATTTACATCGCCTAGTGGTTTACAATCCCACATCATCGAACACGGATTAAACGCTCGACCGTATGATTGTAACTTGTGTCcggcgaaatattttttccgcgCTGAATTAGATAATCATACGATTGAACACGAGAATAATAATGTCGCACCAAATAAATCGGGCAACGTATTAATACCACCGCCACCACCACCAGCTACCGGGCCATCCAATCATACCGGTGAACAAccagaaaatctaaaaaaagaGATGAATTCGGTGGCCGAAGAAAACCGTTGCACCGACGGGGAAGATGTTAAACATCATCCGGATGAGGAGGAGGAATATATCGAGGTGGAAAATTTGGAGACAAGCCACGAGAATAAACtcgataacaaataa
Protein Sequence: MPFKCEYCARLFKHKRSRDRHTKLHTGDRRYKCPHCEAAFSRSDHLKIHMKTHDNQKPFQCTVCNRGYNTAAALTSHMQNHKKQAALLANGGNGGNLNYSPRSTGSTGSSTSSLHKRKYSNIPLDQLNPQQQQQQIHQPHQKLSRSMISCVFCTKSDFQNVDQLNHHVQAMHHQTAAQTPSGGSNPASLTSSPVNPMISCEFCTMKFVSIQQIFQHLKTTHMDRISSPNSYLEHFNRNLMSTYDMAQSALSPSSLLYRNKFLPVVKQESKTPDIPTEAPTNSITSPPVIKHEAEDPPDQESPTDLSQPKSKVFIKDESNHSATSNNNNNASNGDRTPETIQKSPIHQSGTFLCNQCNAALPDFESFRTHLKSHLESGVGSYLCQHCGIPFNDQQIYEKHLFSHFLMNVTEYPCPQTCNKNFTKQEDFQKHMIDAHIQTVYRCEICAEIFDTKISIQVHMSVAHPNEVKLFRCSACMEVYRNERDFRHHVRARHIVSGAVQCIFCRQICSSELDMHFHLAAHARQYRCPVCPESFHVEFLLDRHMQTVHHHGVGSGGAQDRPKEPYHHKITNNNNNNNTIDYHLGGVAKPGHHQSYPFNTNKFYNQLQIDTLNAKHPNLLHGLYDSISKSQRYPPDNGFLSPNKNLLGIYNHPEMIAKLNSFYNQTENGDRLYPPQLQSHSQQAPSATSSASRYPSHTDATIKSHLSGTYSTHHGEKGYSCGMCERNDFSTENEVHSHRKLVHNLKTGVSLRCAYCNGDFRSRSELENHMKVSHNTSGKHKCLICDEIFPSPAVLAEHKLTHCKVGPSGRCSHCLIELKDVTFFKSHLAEHNGHDIPIQCICCRQTLNSEFEIGLHAKFHTKTSEVKENTCALCLETLPPNVETRVCESCYKKHNLNLKTNILQQHTSSSVSNTNNNNNNGSSSSSSANNCNRDSLNINQEAYCNLCKKTLANPIRLQEHLIEHTFAGCDDRGYICYICSSVFTSPSGLQSHIIEHGLNARPYDCNLCPAKYFFRAELDNHTIEHENNNVAPNKSGNVLIPPPPPPATGPSNHTGEQPENLKKEMNSVAEENRCTDGEDVKHHPDEEEEYIEVENLETSHENKLDNK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01460553;
90% Identity: iTF_01052560;
80% Identity: -