Basic Information

Gene Symbol
-
Assembly
GCA_954870665.1
Location
OX940879.1:116131360-116135725[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 3.4e-05 0.0056 18.2 2.9 1 23 424 446 424 446 0.98
2 18 8.7e-06 0.0014 20.1 0.4 1 23 452 474 452 474 0.97
3 18 4.6e-05 0.0077 17.8 1.7 1 23 480 502 480 502 0.98
4 18 5e-05 0.0082 17.7 3.6 1 23 508 530 508 530 0.97
5 18 0.00021 0.035 15.7 4.9 1 23 536 558 536 558 0.98
6 18 7.6e-05 0.013 17.1 5.7 1 23 564 586 564 586 0.97
7 18 3.6e-07 6e-05 24.4 4.3 1 23 592 614 592 614 0.98
8 18 1.3e-07 2.2e-05 25.8 2.4 1 23 620 642 620 642 0.97
9 18 0.00018 0.03 15.9 5.7 1 23 648 670 648 670 0.97
10 18 7.2e-05 0.012 17.2 6.4 1 23 676 698 676 698 0.98
11 18 1.9e-05 0.0032 19.0 4.7 1 23 704 726 704 726 0.98
12 18 1.4e-05 0.0023 19.4 7.1 1 23 732 754 732 754 0.98
13 18 1e-06 0.00017 23.0 7.2 1 23 760 782 760 782 0.98
14 18 0.0016 0.27 12.9 10.1 1 23 788 810 788 810 0.97
15 18 0.00025 0.042 15.5 9.5 1 23 816 839 816 839 0.95
16 18 0.00013 0.021 16.4 0.4 1 23 845 867 845 867 0.97
17 18 0.0013 0.22 13.2 3.3 1 23 877 899 877 899 0.98
18 18 3.9e-06 0.00065 21.2 1.6 1 23 905 928 905 928 0.97

Sequence Information

Coding Sequence
ATGAATACAGGCGATCGGTCCGTACCCCACGAGAATTCCGGGCCCGACTCGCAAATTCGGCAGTCGCCATCGCAACCCCAGTCGCAGCAGGCGCATCcccagcagcagcaacaacaccCCCAACATCAACGGCACTTGCATCAACAGCAAATTGACGAGCAAAATCGtcagcaacaacagcagcagcagcaacatcAACAGCAGCAGCATCCGTCACAAGGTGGACACCAACAAGAGCAACGAATAGGTGGTGTGATCCAACCTGTGAGTGAAGCGGAAATTAAACACTCCTTGCCATTGGCCAACGCACCGCAGCTCGGTAAATATTGGGTGGTTACCAACTTGTTCCAAGGGCCTGGTCAAAATGCGACAGCGTATAATGTGGGGCAGCCAACATCCTCGTCGGGAGGAGTGGTCATCCCAACTGCTCAACAAAGTCAATCACATCCCGCCCTGAAGCCTGAAGCGATAAAACAGGAAGAAGCTAATATCCATCAGCACCGGCATATTCAGCAGCAGATAGTGACGGTTAGCGCACCAAATACCATCCAGATACCGAACTCGATGATAGTGACGCAGCAGGGCTCGCAACAATTAACCAATGCGACGCTACTACAAACCAACCAGCCTGCTGAGCATATTCAGGTGGCTGTGAACCCGGAGAACAGTATTATGATAATGGACACATCGtccaataaaaatgaaaaagtaatgaCGAACCAAAATCTCAACACGAACGAGTCAATGCAAGGCATCGAGCGAGTGAAGGAAGAGAAACCGTTTGTTAACTGCAAAATGTTGCCGCATCAGCAGCACCTGCACAATCAGCAAATGGGCGGGGATCAGAAGATGCACATCTCTCATCTGCTGGATGTAAGAAACACCGACGGATCCTTGATTAAGATTCAACCGCAGGACCAAGAGATGGGGAAACCACTGGGTGTGGAAATGTACAAAGTGAACATTGAAGACCTGAGTCAGTTCCTTTCATATCACGAAGTGTTCGGAAAATTGCACAGCGGCGATGTGATCACGCATCCTATTTCGCACACGGGCACTCACGTCGTGAACACTGTGAGTAACGCACCCACGACTGTTAAGACGTCTACTACAAATGTTGTAGCTTCGGGTGCAAATATTGCAACCTCAACAGGAGAGCTCTTGATGCCGAAAATGGAAACTGTAACACAGATAGCCGGCGTGAACCAAGTTCCCGGAACGGTGGGTACCCTCACAAATGCTGATGGAACTACAATTACTCCTGCCACTCACACATGCGATATTTGTGGGAAAATGTTCCAATTCCGCTATCAACTGATCGTTCACAGACGCTACCACAGCGAGCGCAAGCCCTTTATGTGTCAAGTTTGCGGTCAAGGCTTCACTACGTCCCAAGATTTAACGCGCCATGGTAAAATACATATAGGTGGACCAATGTTCACGTGCAACGTGTGCTTTCATGTGTTTGCAAATGACGCGAGCTTAGAGCGTCACATGAAAAGGCATTCGGCCGACAAGCCATTCGCGTGCACAATGTGCCAGAAAACATTTGCACGAAAAGAGCACTTAGATAACCATTTCCGAAGTCATACGGGCGAAACTCCATTTCGGTGTCAGTTTTGTGCAAAAACGTTTACCCGCAAAGAGCATATGGTGAACCATGTTCGAAAGCATACCGGCGAAACGCCACATCGATGCGATATCTGCAAGAAATCATTCACAAGAAAAGAGCATTACGTTAACCATTATATGTGGCACACTGGCGACACACCGCATCAATGTGAAGTGTGCGGTAAAAAGTATACGAGAAAAGAACACTTGGCGAACCATATGCGATCCCACACAAATGATACGCCATTCCGATGTGAGATTTGTGGGAAGAGCTTTAGTCGGAAAGAACATTTCACAAATCATATATTGTGGCACACAGGTGAAACCCCGCATCGTTGCGACTTCTGTGCGAAAACTTTCACGCGAAAGGAGCATCTGCTAAATCATGTCCGGCAGCACACTGGTGAATCACCACATCGTTGCACGTACTGCCTGAAAACATTCACGCGCAAGGAACATCTCGTTAATCATGTGCGGCAGCATACTGGGGAGACGCCTTTCAAGTGCACGTTCTGCACAAAGGCGTTCACGCGTAAGGATCATATGGTAAATCACATACGACAGCATACTGGAGAATCACCACACAAGTGCACCTACTGTACGAAAACGTTCACTCGAAAAGAACATCTTGTCAATCATGTTAGACAACATACAGGCGAATCACCGCATCGGTGTTCGTACTGCAATAAAACATTCACGCGCAAGGAGCATTTAACGAATCACATCCGTTTGCATACTGGCGACTCGCCGCATAAGTGCGAATGTTGTCAGAAAACATTTACTCGCAAAGAGCACTTAAATAATCATATGAAGCAACACTCGAGCGACAATGCGCATTGTTGCAATGTTTGTAACAAACCGTTTACACGCAAGGAGCATTTGATAAATCACATGTCGCGATGTCATACAGGCGATCGACCATTTGCATGCGAAACTTGTGGGAAATCTTTCCCTCTAAAAGGAAATCTTATCTTCCATCAAAGGAGCCATACTAAAGGTCAAGATGTCGAGCGTCCCTTCCGGTGTGAGAAATGCCCAAAAGATTTCATTTGTAAAGGTCATTTAGTGTCGCATATGCGGGCGCATTCAGGAGAGAAACCGCATGTTTGTTCGCTGTGTAGCAAAGCGTTCGTGGAAAAAGGAAATCTCAAACGACATATGAAAATGAATCATCCAAATGTGATCATTCCACCACTTGGACTGGTAACTAATATAAAAACTGAAGCGATTCCAACGACCGTCACAACGGTGGTGTCGCAGTATAATACAATAAAAACGGAAACCAATCCTACCACAATGGCAACCGCTCCTCAATATATGAACGAGCGAATTCAGTTGCTTACAAAAGCGAACTTGCTGCCTATAAATCCTCTAATTCCTCACCAAGCGCCTACTATGCACACAATACAACAAATAACTGCTACATCGGCAAATTCAACAATTAGCAATACGAGCTCATTGTCGGGAGCAACTGGGCTAGTTCCGATAGTTACTTCAACAATTACTTCACACGCAAgccaacaacagcagcaacaacaacaacagcagcagcagcaacaacaacaacagcaacaacatgTGCAGGCCCAAttacaacaacagcagcagcaacagcaacaacaacaacaacagcagcaacaacaacaccaacagcagcaacaacaacctccgcaacagcaacaacaaaacaactctGGTGATCCTACCCAAACAGTTCCCATCGCCATCATACAGGCTGGCGATCCAACCACAATAACGAGAGCATCGATTCAGCTGCAACACCTTCCGCCCGGTGTAGATCATCATTCTGTTGTCTACTAG
Protein Sequence
MNTGDRSVPHENSGPDSQIRQSPSQPQSQQAHPQQQQQHPQHQRHLHQQQIDEQNRQQQQQQQQHQQQQHPSQGGHQQEQRIGGVIQPVSEAEIKHSLPLANAPQLGKYWVVTNLFQGPGQNATAYNVGQPTSSSGGVVIPTAQQSQSHPALKPEAIKQEEANIHQHRHIQQQIVTVSAPNTIQIPNSMIVTQQGSQQLTNATLLQTNQPAEHIQVAVNPENSIMIMDTSSNKNEKVMTNQNLNTNESMQGIERVKEEKPFVNCKMLPHQQHLHNQQMGGDQKMHISHLLDVRNTDGSLIKIQPQDQEMGKPLGVEMYKVNIEDLSQFLSYHEVFGKLHSGDVITHPISHTGTHVVNTVSNAPTTVKTSTTNVVASGANIATSTGELLMPKMETVTQIAGVNQVPGTVGTLTNADGTTITPATHTCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCNVCFHVFANDASLERHMKRHSADKPFACTMCQKTFARKEHLDNHFRSHTGETPFRCQFCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGDTPHQCEVCGKKYTRKEHLANHMRSHTNDTPFRCEICGKSFSRKEHFTNHILWHTGETPHRCDFCAKTFTRKEHLLNHVRQHTGESPHRCTYCLKTFTRKEHLVNHVRQHTGETPFKCTFCTKAFTRKDHMVNHIRQHTGESPHKCTYCTKTFTRKEHLVNHVRQHTGESPHRCSYCNKTFTRKEHLTNHIRLHTGDSPHKCECCQKTFTRKEHLNNHMKQHSSDNAHCCNVCNKPFTRKEHLINHMSRCHTGDRPFACETCGKSFPLKGNLIFHQRSHTKGQDVERPFRCEKCPKDFICKGHLVSHMRAHSGEKPHVCSLCSKAFVEKGNLKRHMKMNHPNVIIPPLGLVTNIKTEAIPTTVTTVVSQYNTIKTETNPTTMATAPQYMNERIQLLTKANLLPINPLIPHQAPTMHTIQQITATSANSTISNTSSLSGATGLVPIVTSTITSHASQQQQQQQQQQQQQQQQQQQHVQAQLQQQQQQQQQQQQQQQQQHQQQQQQPPQQQQQNNSGDPTQTVPIAIIQAGDPTTITRASIQLQHLPPGVDHHSVVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

90% Identity
iTF_00793687;
80% Identity
-