Basic Information

Gene Symbol
-
Assembly
GCA_014839585.1
Location
QVOB01001746.1:13291-18255[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 1.1e-05 0.0013 19.5 2.5 1 23 655 677 655 677 0.97
2 17 0.17 19 6.3 2.2 1 14 683 696 683 701 0.90
3 17 0.15 17 6.5 0.4 2 23 710 731 709 731 0.95
4 17 0.00075 0.085 13.7 2.1 3 23 740 761 739 761 0.98
5 17 0.0017 0.19 12.6 1.5 2 23 769 791 768 791 0.96
6 17 7.8e-05 0.0088 16.8 0.7 1 23 797 820 797 820 0.94
7 17 0.53 60 4.8 0.6 2 23 828 848 828 848 0.95
8 17 5.2e-07 5.9e-05 23.7 2.3 2 23 854 875 853 875 0.97
9 17 4.2e-06 0.00047 20.8 0.3 1 23 881 903 881 903 0.99
10 17 0.00026 0.029 15.2 2.4 2 23 915 937 914 937 0.95
11 17 0.0033 0.38 11.7 3.3 1 23 943 966 943 967 0.95
12 17 0.0097 1.1 10.2 1.4 2 23 982 1004 981 1004 0.94
13 17 3.4e-05 0.0039 18.0 0.4 2 23 1011 1033 1010 1033 0.97
14 17 0.00012 0.014 16.2 1.7 3 23 1042 1062 1041 1062 0.98
15 17 0.00099 0.11 13.4 2.3 1 23 1068 1091 1068 1091 0.96
16 17 1.1 1.2e+02 3.8 4.1 2 23 1098 1119 1097 1119 0.96
17 17 0.0078 0.89 10.5 2.6 1 23 1125 1147 1125 1147 0.98

Sequence Information

Coding Sequence
ATGTTTTCTACAAGCAGTAGATGTGATCACAATTACAGCGGGGTGGAGCCTTCTCTACTCGCAAGCAATAGCGATGATGCTTCTAAGACAAGTATAGAATCCCAGAAGTCATCAATCTCATTTATAAAAGATAACAAGAGCACCACTTGTCAACAAAAAATGTTGCCTATTCCAGAAAAGACACGTCAAGCACTAACAAGATATTGTCGTACCTGTGCTAGTATAAAAATGCCCTTGATTGATATTTTTAGCAAGAAAGGTATGGAAATGCGACTAAGTCACCAAATTAAACATCTATATCAGATCAATCGTAATAGTCTTACCACACAAATGTGTATAGACTGTATCTACGATCTTAAAATGAGCTACAAATTTTTTACGCAAATCAAAAAAGCTGAAAGAAAACTTGCATTTATCTTTAATAATTTAAGCAAGGAATTAGTGGATGAAGAATCTTCTTCAAAACATCAGGAAAAACAATCATGTTATATAGAAAAAGAAATACCATCTTCTAAATATCAGAAAGATTCTGTCGTTCCGGAAACACAGAGTCGCCAATCATTTACAACACAACAAAACTCCCAAAACTCAACAACTTCTAAAAATGAAGAAGAAAGCGATTCTGTTTCCAGAACTATCGTTAAGATGGTTCCACTGCAAAATGAGTCGGAAAACGATTCTAGAGCGAAGGAAGACAAACAGATGGATAAGAATATTATCGAAGTAACTAGGGAGGATGATGAGGATTCTATCGTGGAATTTGATCCCGAAGATCAATCTACACAGGAAAATGAAGAAGTACAAGTATCTTCAAATTCCTCTGTCACAATTTACACATACAATACAACAGCTGAGTCCTATGTGATGGTGGAAAATGATAAGGCAAAAACTTCTCTAACACCCGAGGTCTCTCAGATCTTAACAAATGAGGAAGAAAAGCAAAAAGAGGAAACAAGGCAGCCGAATATTCTGAAAAGAAGGTTACTAATGCCATCTACGAAAAAAGACGAGGCGGAAGATGCAGCACAAAATGGAGTAGAGGATTCTTCACAAGATGCTCCAAAGGACTGTAAAATACAAAAGCTGGATTTAAGTAATCCGTTGAATGTAAATGTCCCGAATGAGGACGGGATTATGTACATGACTATGAAAGGATCAGCAAACAGCACTCTATTGATGAAAGTTAAAAAAGTGGATAAACCTGTGGAACCAAAACGTTTCCTTGTACGTTATAATCAAGCAGGAACATCTCAACGTACTGATTCTCGCGAACAAATAATTGAGGAACAAATTGAAGAGTATAAAAAGAAACGAGAAAAAGTTCTCGGTAATCAGTCACCAGCCACTTTAATAGCGAACGCGAAAGAAGTTCAACCACAAAAAGAAGTGTCGACGCAAAAAGAAGTTCCAACGCAAAAAGAAATCCCAACGCAAAAAGAAATCCCAACGCAAAAAGAAATCCCAACGCAAAAAGAAATCCAAACGCAAAAAGAAGTTTCAATACAAAAAAAAGTTCCAACGCAAGAAGAAGTTCCTGTCCAAGACAATTTTGAAAGCATAGAAATATCGGATGACGAGAAAACAGAAGAGACTGAGAAAACGGACGAAGATCAGGAAAAAGTAGATGCCAATACAAACGAATTTGCTTCGAGATTATCAAAATTGAAACAGAAGTGGGAAGAGGCGAGACGAAAGAAAATAAGCTCGCAGAAGAAAGACTTAAATGAGTCATATAACGAAGAAAATTTAGAGAGATTGGCCAAAGTTTTAGGAAATAACAATACAAACTTGAAGGAATTTCTGGATTATCTAAAGCAACGAAAAATTGTGCTTACACGTCTCAAAGATGAAGATATAATTTCTCTCTACGAAGATCGTTTTTCTATAAAATCAGTTGTTAAACCTCTTCCGGATCTTATTGATACTCAACCACCGAGTGATGCTCTTCCGGAAGAAAATTATTTTGACTGCGATTATTGTCCGAAAACCTTTTCTACCTGTGAGAAACTTGAAGAACATCTTAAATCACACGATTATCACATCCTTCATTATTGTGAGGACTGCGGGGAAGAATTTTCGACACAGAAAGCAAAAAGATGTCATAGTGTCATATGTGTGAAAAAGTTGATTTGCCAATATTGCGACATTATTTTTGAAGGCAAAGGGAAAAAGCGTCAACATGAGCAAAAACATATAGATGATCTTTACGGTCAGCTTTGCGAGTTCTGTGGAGAAAAATTCAAACATCAGGGCACATTGGATCAACACGTTAAAACGCGTCATACGATCTTAGAGAAAACCATACAATGTCCGAAATGTCCGAAAAAATTTACGATGAAGCAAAAGTTGAGTTTTCACATGAAATCAGTCCACACGACCTCGAGAGCGTATCTTTGTGAAGACTGCGGAGCAGATTTTAAGAATCCCGCGAGTTTGAGACATCATAGAATCAGAAAACATCAATTGGTTGGGAACAAGAGGGAATGTCCGGTTTGTAGAAAAATAGTGCCTTTTTATGGTTTATCCAAACACATGCATACACACAAGGCTTACAGTATTCAATGTCCGCACTGCGATAAGATGTTCAAAAACACATCGACTTTGAAGCAACACGTGAGGATTCACGAAGATCAAAGGCAGTATCGTTGCGATACCTGCGGAGTTGGTTTTAATCGAAGAGACGGTTTAAGACTGCACATGAAAGTGCATGAAAAATCGGGCAGCAGAGGTTTGAAAGAGTGTTCTTGCCAAATTTGTGGAGAGAAGTTCCCAAATCACTCGACTTTGGTGATTCACAGAAACCGAGTACACAAGGATGGGAGACAATATACCTGCCACATTTGCAACAGATCAATGATCTCGTCGAGGTCTCTTGAATGGCACATGGCACATATTCATCATCAGTCGATGCCAGGCTCCACTAACGAATCTGAACAACGGGTTTCTTGTTATCAATGCAATAAAACATTCAAAACGGAAATGATCTTACGAACGCACATCAAGAACACACACATAATCAAAGACCCGGTAAAATGTCCCGATTGCGATCTCATGTTCAAATCTGAAGTGCGTCTACGTCATCACATGATGGTCGCGCACAATCGTTTGGAAGGCACTTTACTATGTCCCCATTGTCCGAAACGTTTTGTCAATCAATTGAGGCTCAAGACTCATATGATTTCTCATTCCGAGGAAAGACCGTACACTTGCGAGATCTGTGGTTTTAATCTTAAGACGAAGATTCAACTGATCAAACATCATCAGAATCGACACAGTGATGAGAGACCTCTGCAGTGCAGATACTGTAGTTGGCGATGCAAACAAGTGAGTGCTCTTGTCTGTCACGAGCGTACGCATACCAATGAGCGTCCATACTCGTGTAGCGTATGCCGGCAGCGCTTCAAATATCTAGGTGACAAAAACAAACATGAGCGGCGTCACGAAAGTCTTGGTGGTTCAGGATTCAAACGTATTGTGCCAGTGAGAACTGTTAAAGCGAAAGAACAACGTACTGACGATTCTTCCGTATCTGAGCAAGATCAAGGTTCTCAGGACTCTATAGTTACCCAAGATACTCAAAAATTATATGAAGAGCAACAGACAGAGGAATTCAGAGAACAGGCCGAATTGAAGCATGAAATTGATATCGAGACTGCTGAAGGTTACGAACAGAAATACGAGGAAAGTTCGAGAGAAACATCGGAAGCTACAGAATTAATAATGAACATGGAAGATTCCAATGTATATACGGAAGAAGTAACAGCTGATAGTATAGAATCCAATGTGGAGATTATAACGGACGAGATAATGACGAATGACATTTTGCAATCGGGAACTACAGCTGTGGTACATCTGCAAGAAGACGATACAGGGAAGATTCAAGTGATACCTGTGATGCTTGATCTGTCTGATGCAAACACTGAAGTCGCTCTTCCAACCGCGTCTATTATGTATAATAATTAA
Protein Sequence
MFSTSSRCDHNYSGVEPSLLASNSDDASKTSIESQKSSISFIKDNKSTTCQQKMLPIPEKTRQALTRYCRTCASIKMPLIDIFSKKGMEMRLSHQIKHLYQINRNSLTTQMCIDCIYDLKMSYKFFTQIKKAERKLAFIFNNLSKELVDEESSSKHQEKQSCYIEKEIPSSKYQKDSVVPETQSRQSFTTQQNSQNSTTSKNEEESDSVSRTIVKMVPLQNESENDSRAKEDKQMDKNIIEVTREDDEDSIVEFDPEDQSTQENEEVQVSSNSSVTIYTYNTTAESYVMVENDKAKTSLTPEVSQILTNEEEKQKEETRQPNILKRRLLMPSTKKDEAEDAAQNGVEDSSQDAPKDCKIQKLDLSNPLNVNVPNEDGIMYMTMKGSANSTLLMKVKKVDKPVEPKRFLVRYNQAGTSQRTDSREQIIEEQIEEYKKKREKVLGNQSPATLIANAKEVQPQKEVSTQKEVPTQKEIPTQKEIPTQKEIPTQKEIQTQKEVSIQKKVPTQEEVPVQDNFESIEISDDEKTEETEKTDEDQEKVDANTNEFASRLSKLKQKWEEARRKKISSQKKDLNESYNEENLERLAKVLGNNNTNLKEFLDYLKQRKIVLTRLKDEDIISLYEDRFSIKSVVKPLPDLIDTQPPSDALPEENYFDCDYCPKTFSTCEKLEEHLKSHDYHILHYCEDCGEEFSTQKAKRCHSVICVKKLICQYCDIIFEGKGKKRQHEQKHIDDLYGQLCEFCGEKFKHQGTLDQHVKTRHTILEKTIQCPKCPKKFTMKQKLSFHMKSVHTTSRAYLCEDCGADFKNPASLRHHRIRKHQLVGNKRECPVCRKIVPFYGLSKHMHTHKAYSIQCPHCDKMFKNTSTLKQHVRIHEDQRQYRCDTCGVGFNRRDGLRLHMKVHEKSGSRGLKECSCQICGEKFPNHSTLVIHRNRVHKDGRQYTCHICNRSMISSRSLEWHMAHIHHQSMPGSTNESEQRVSCYQCNKTFKTEMILRTHIKNTHIIKDPVKCPDCDLMFKSEVRLRHHMMVAHNRLEGTLLCPHCPKRFVNQLRLKTHMISHSEERPYTCEICGFNLKTKIQLIKHHQNRHSDERPLQCRYCSWRCKQVSALVCHERTHTNERPYSCSVCRQRFKYLGDKNKHERRHESLGGSGFKRIVPVRTVKAKEQRTDDSSVSEQDQGSQDSIVTQDTQKLYEEQQTEEFREQAELKHEIDIETAEGYEQKYEESSRETSEATELIMNMEDSNVYTEEVTADSIESNVEIITDEIMTNDILQSGTTAVVHLQEDDTGKIQVIPVMLDLSDANTEVALPTASIMYNN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

90% Identity
iTF_01271403;
80% Identity
-