Nmel010405.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Netelia melanura
Gene Symbol
LZTR1
Assembly
GCA_964007305.1
Location
OZ023255.1:35953375-35956199[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 2.5e-15 8.5e-13 49.0 0.1 2 108 348 485 347 487 0.88
2 4 1.1 3.8e+02 1.9 0.1 75 107 484 516 478 519 0.81
3 4 5.4e-20 1.9e-17 64.0 0.0 8 96 578 666 572 681 0.84
4 4 1.2 4.1e+02 1.8 0.1 76 100 680 704 676 713 0.80

Sequence Information

Coding Sequence
ATGGCTACTGCCGAATGTCTGACTTTGGATTTTGGTCCATTTGAGACCGTACACAGATGGCAACGTATGCCGGAGTGTGATGAATTTGTGGGGGCTAGACGCAGCAAGCACACAGTTGTTGCATACAAAGATGCTATTTATGTATTTGGTGGAGATAATGgcataaaaatgttaaatgaTGTTCTGCGTTTTGATGCAAAGGAAAAATCTTGGGGACGAGCCATTGCTACAGGTGCAGCACCCGCACCTCGTTATCATCATTCAGCAGTTGTTCATGATTCGTCTATGTTTGTGTTCGGAGGGTACACAGGCGATATTCATTCCAATTCTAATCTTACCAATAAAAATGATCTGtttgaatataaatttcaaacgggacagTGGACAGAATGGAAATTTATTGGAAAAACACCAGTGGCGCGATCCGCTCATGGTGCAGCAATTTTCGATAACAAACTCTGGATATTTGCTGGATACGATGGAAACGTTCGTTTGAACGACATGTGGACAATTTCTTTATCACCGGGTGAGCCACGGATCTGGGAGGAGGTCGTTCAGTCTGGGGACTGTCCTCCTACTTGCTGCAATTTTCCTGTTGCTGTTGCTCGTGAATCCATGTTTGTGTTCAGTGGTCAAAGCGGTGCGAAAATTACGAACAGCCTTTTTCAATTCCACTTCAGAGACAAACGATGGACTCGTATCTCTACCGAGCACATTTTACGTGGTGCACCTCCTCCACCAGCGCGTCGTTACGGTCATACGATGGTAAGTTTCGACCGTCATCTGTATGTTTTCGGTGGGACTGCAGATTCGACGTTGCCCAACGATCTCCACTGTTACGATCTCGATACACAAACCTGGAACATCATACTACCATCAGCCGCGAGTCAGATACCATCGGGACGTTTGTTTCACGCTGCAGCTGTTATTGGTGAAGCGATGTTCATTTTTGGTGGAACGGTGGACAACAACGTCCGTTCCGGTGAGACATATCGTTTTCAATTCTCATCGTATCCAAAATGTACGTTACACGATGATTTCGGCAAATTGTTGAATTCCCGACTGTTTTGTGACGTCGAGTTCGTCGTTGGTGAGCTTGAAACAGAAACTAAGATACCAGCCCATATGGCTATGGTAGCGGCGAGATCGGAGTTTCTCAGTGCTCGAATAAAACAAGCGAGAGAACGGCGTGAAAAACGTTTGGAGAAAGTCATGAGTACCAAAATACCGAATCAAACTACAACGTGGCTTGAAGTCAAACTCGAGGATGTCGTGCCTGAGGCTTTTGAGATGGTGCtcaattatatatacacagatcGTATCGACCCTACGAAGAGAATCGATGATCCCGAGCCTGGAAATCGCATTGTTCTCCTTATGATGGACGTATACCGTTTAGCCGTTCAATTTAATATGGAACGTTTGGAACAGCTTTGTGTTCATTATCTCGAAGCTACGATAACACACGCAAACGTGCTGGAGGCATTACACAACGCAGCCCATCTCAATCTTCATTTTATCAAAGAGATATGTCTTGGTTTTGTCGTCAAGGAGATCAATTACAATCAGATTGTTATGAGTCAGGAGTTCGAGACTCTCGATCAACCACTGATGGTCGAAGTAATAAGACGACGACAAATGCCACAGACGCGGAACTTCTCGAAGCAATACGAGTCCGGTACAGGAACTACATTGGAGCAGGATATGGAAGCATTTCTGAAAAGTGTCGGACATGAATTTTGCGATATCACACTGATGCTCGATGGCGTACCGATACCTGCTCACAAAGCCGTTCTCGCGGCACGCTGCAGTTACTTTGAGGCGATGTTCCGATCGTTTATGCCTGAGAACAATACGGTCAACATTCAAATAGGCGAGATGATACCGTCCTCGGAATCATTCGCGTCACTTCTCAGATACATATATTACGCGAACGTGGCCATGCCACCCGAGGACTCGTTGTATCTCTTTACGGCTCCAGTATTCTACGGGTTCACGAACAATCGTTTGCAAGCATTTTGCAAACAGAATCTAGAAATGAATGTTACTTTTGAGAACGTTATACAAATATTGGAGGCGGCCGATAGGATGCAAGCAGCGGATATGAAGAAATATGCTTTGAATCTTATAGTGCATCATTTTAGCAAGGTCGCTCGGCTACCCAGGCTCAAGCAGCTGAGCAGAGACCTTCTACTGGATATATTGGAAGCCTTGGCGGACGAGCAAAGCGAAGCGCGTACGTGTCAGGATATGACGAGCGATTGTTGA
Protein Sequence
MATAECLTLDFGPFETVHRWQRMPECDEFVGARRSKHTVVAYKDAIYVFGGDNGIKMLNDVLRFDAKEKSWGRAIATGAAPAPRYHHSAVVHDSSMFVFGGYTGDIHSNSNLTNKNDLFEYKFQTGQWTEWKFIGKTPVARSAHGAAIFDNKLWIFAGYDGNVRLNDMWTISLSPGEPRIWEEVVQSGDCPPTCCNFPVAVARESMFVFSGQSGAKITNSLFQFHFRDKRWTRISTEHILRGAPPPPARRYGHTMVSFDRHLYVFGGTADSTLPNDLHCYDLDTQTWNIILPSAASQIPSGRLFHAAAVIGEAMFIFGGTVDNNVRSGETYRFQFSSYPKCTLHDDFGKLLNSRLFCDVEFVVGELETETKIPAHMAMVAARSEFLSARIKQARERREKRLEKVMSTKIPNQTTTWLEVKLEDVVPEAFEMVLNYIYTDRIDPTKRIDDPEPGNRIVLLMMDVYRLAVQFNMERLEQLCVHYLEATITHANVLEALHNAAHLNLHFIKEICLGFVVKEINYNQIVMSQEFETLDQPLMVEVIRRRQMPQTRNFSKQYESGTGTTLEQDMEAFLKSVGHEFCDITLMLDGVPIPAHKAVLAARCSYFEAMFRSFMPENNTVNIQIGEMIPSSESFASLLRYIYYANVAMPPEDSLYLFTAPVFYGFTNNRLQAFCKQNLEMNVTFENVIQILEAADRMQAADMKKYALNLIVHHFSKVARLPRLKQLSRDLLLDILEALADEQSEARTCQDMTSDC