Hami015455.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Heteropelma amictum
Gene Symbol
Lztr1
Assembly
GCA_959613375.1
Location
OY390728.1:4465661-4469637[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 1.7e-13 4.8e-11 42.9 0.2 2 108 348 486 347 488 0.90
2 3 5.8e-19 1.6e-16 60.5 0.0 9 96 580 667 572 683 0.85
3 3 0.97 2.7e+02 1.8 0.1 76 100 681 705 676 714 0.80

Sequence Information

Coding Sequence
ATGGGCACCGCCGAATGCCTCACTTTGGATTTTGGTCCGTTTGAGACTGTGCACCGATGGCAACGTATGCCAGAATGTGATGAATTTGTCGGAGCCAGACGCAGCAAGCACACGGTAGTCGCTTACAAAGATGCTATTTATGTATTTGGTGGAGATAACGGTATAAGAATGTTAAACGACCTTCTGCGCTTTGACGCTAAAGAAAAGTCTTGGGGACGAGCTATCGCTACTGGATCACCACCAGCTCCGAGATATCATCATTCGGCGGTTGTTCATGATTCTTCCATGTTTGTATTTGGCGGATATACCGGCGATATTCACTCCAACTCAAATCTCACCAACAAAAATGATCTCTTTGAGTACAAGTTCCAAACTGGACAGTGGATAGAATGGAAATTTATTGGAATAACTCCAGTGGCGCGTTCCGCTCACGGAGCTGCAATTCACGACAACAAACTCTGGATATTTGCCGGCTACGATGGTAATGTTCGTTTAAACGACATGTGGACGATATCTCTATTACCGGGAGAATCTAGGGTCTGGGAAGAGGTAGTTCAATCGGGGGATTGTCCGCCAACTTGTTGCAACTTTCCCGTTGCTGTGGCCCGCGAATCAATGTTTGTGTTTAGCGGTCAAAGTGGCGCTAAGATCACAAATAGCCTATTCCAGTTTCACTTCCGAGACAAACGATGGACCCGTATCTCCACGGAGCATATATTGCGCGGCGCTCCACCTCCTCCAGCGCGACGTTACGGCCATACAATGGTCAGTTTTGATCGTCATCTGTACGTTTTTGGCGGAACAGCAGATTCAACGTTACCCAACGATCTTCACTGTTACGATCTCGATACCCAAACGTGGAACATCGTTTTACCGTCGGCCTCGAGTCAGATACCATCTGGACGTTTATTTCATGCGGCGGCCGTTATCGGCGAAGCGATGTTCATCTTTGGTGGTACCGTCGACAATAATGTACGTTCAGGGGAAACATATCGCTTTCAATTCTCGTCTTATCCGAAATGTACGCTTCATGATGATTTCGGCAAACTGTTAAATACTCGTTTATTCTGCGACGTTGAATTTGTCATTGGTGAACTCGAGATTGAAACGAAGATACCAGCTCATATCGCTATGGTCGCGGCGAGGTCAGAGTTTCTGAGTGCTCGTATTAAACAATCTAgggaaaaacgcgaaaaacatCTTCAAGATGTTTTTGGTACTATTGACGTTTCGATAAAAGATATGCCATTGCTCGAAGTTAAATTGGAAGATGCTGTTCCCGAGGCCTTCGAGATGGTGCTCAATTATATATACACCGATCGCATAGATCCAAcgaggaaaatcgatgatCCAGAGCCGGGTAACCGTATAGTTTTATTGATGATGGATGTATATCGTTTGGCTGTACAATTTAATATGGAATGTTTGGAGCAACTTTGCGTTCATTACCTTGAAGCGACTATAACACATACAAATGTTCTTGAGGCATTGCACAACGCGGCTCATCGCAATCTTCATTTCATCAAGGAAATATGCCTTGGTTTTGTTGTAAAAGAAAGCAATTATAATCAGATCGTAATGAGCCAGGAATTTGAAACGCTCGATCAACCGTTGATGGTTGAGGTAATAAGACGAAGGCAGATGCCTCAGACAAGAAATTTTACAAAGCAATATGAGCCTGGCACGGGCACCACGTTACAGCAGGATATGCAAGCGTTTTTGAAGAGTGTTGGCCGCGAATTTTGCGATGTCACGCTTATACTCGATGGTGTACCGATTCCAGCACACAAAGCGGTCCTTGCTGCACGTTGCGGCTACTTCGAAGCTATGTTTCGATCATTCATGCCTGAGAACAATATAGTTAACATTCAAATAGGTGAGATGATTCCTTCTTCGGCGTCATTTGCATCGCTCTTGAGATACATATATTACGCGGACGTGGCTATGCCACCAGAGGACTCGTTATATTTATTCACGGCTCCGGTTTTTTACGGATTTACGAATAATCGTCTTCAGGCATTTTGCAAACAGAATCTCGAGATGAACGttacttttgaaaatgtcaTACAAATATTAGAGGCTGCCGATAGAATGCAAGCTGCTGATATGAAGAAATATGCTTTAAACCTCATCGTTCATCATTTCAGTAAGGTCGCGCGATTACCGAGGCTCAAGCAGCTGAGCAGAGATCTTCTGCTGGATATATTAGAAGCCTTGGCTGATGAACAAAGCGAGGTCCGTACTTGTCAAGATATGACTAGCGATTGCTGA
Protein Sequence
MGTAECLTLDFGPFETVHRWQRMPECDEFVGARRSKHTVVAYKDAIYVFGGDNGIRMLNDLLRFDAKEKSWGRAIATGSPPAPRYHHSAVVHDSSMFVFGGYTGDIHSNSNLTNKNDLFEYKFQTGQWIEWKFIGITPVARSAHGAAIHDNKLWIFAGYDGNVRLNDMWTISLLPGESRVWEEVVQSGDCPPTCCNFPVAVARESMFVFSGQSGAKITNSLFQFHFRDKRWTRISTEHILRGAPPPPARRYGHTMVSFDRHLYVFGGTADSTLPNDLHCYDLDTQTWNIVLPSASSQIPSGRLFHAAAVIGEAMFIFGGTVDNNVRSGETYRFQFSSYPKCTLHDDFGKLLNTRLFCDVEFVIGELEIETKIPAHIAMVAARSEFLSARIKQSREKREKHLQDVFGTIDVSIKDMPLLEVKLEDAVPEAFEMVLNYIYTDRIDPTRKIDDPEPGNRIVLLMMDVYRLAVQFNMECLEQLCVHYLEATITHTNVLEALHNAAHRNLHFIKEICLGFVVKESNYNQIVMSQEFETLDQPLMVEVIRRRQMPQTRNFTKQYEPGTGTTLQQDMQAFLKSVGREFCDVTLILDGVPIPAHKAVLAARCGYFEAMFRSFMPENNIVNIQIGEMIPSSASFASLLRYIYYADVAMPPEDSLYLFTAPVFYGFTNNRLQAFCKQNLEMNVTFENVIQILEAADRMQAADMKKYALNLIVHHFSKVARLPRLKQLSRDLLLDILEALADEQSEVRTCQDMTSDC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00087267;
90% Identity
iTF_01056144;
80% Identity
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