Mcix000532.1
Basic Information
- Insect
- Melitaea cinxia
- Gene Symbol
- -
- Assembly
- GCA_905220565.1
- Location
- HG992236.1:8736597-8741593[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 29 0.099 11 7.5 0.7 1 21 70 90 70 91 0.96 2 29 0.016 1.7 10.0 0.4 2 23 163 184 162 184 0.97 3 29 0.018 1.9 9.9 0.1 1 23 188 210 188 210 0.95 4 29 0.49 53 5.3 0.8 1 15 215 229 215 238 0.78 5 29 0.05 5.4 8.5 0.2 1 23 244 267 244 267 0.94 6 29 0.002 0.22 12.8 1.2 1 23 274 297 274 297 0.98 7 29 0.00035 0.037 15.3 0.7 1 23 304 326 304 326 0.97 8 29 0.0068 0.72 11.2 0.2 1 23 400 423 400 423 0.96 9 29 8.9 9.5e+02 1.4 4.6 2 23 450 472 449 472 0.94 10 29 0.074 8 7.9 4.7 1 23 494 516 494 516 0.98 11 29 6.9e-05 0.0073 17.5 0.8 1 23 520 542 520 542 0.98 12 29 0.00089 0.095 14.0 0.1 1 21 576 596 576 599 0.90 13 29 0.014 1.5 10.2 1.7 1 21 606 626 606 627 0.93 14 29 0.085 9.1 7.7 0.8 1 23 671 693 671 693 0.97 15 29 0.007 0.75 11.1 0.3 2 23 718 740 717 740 0.96 16 29 0.0071 0.76 11.1 1.7 1 23 762 784 762 784 0.98 17 29 0.026 2.7 9.4 4.6 1 21 788 808 788 810 0.95 18 29 0.46 50 5.4 0.1 3 23 817 838 815 838 0.83 19 29 0.0036 0.39 12.0 4.0 1 23 844 867 844 867 0.96 20 29 0.057 6.1 8.3 4.1 1 23 908 930 908 930 0.94 21 29 1 1.1e+02 4.3 0.1 2 23 954 976 953 976 0.93 22 29 0.00055 0.059 14.6 3.7 3 23 1000 1020 999 1020 0.98 23 29 0.00032 0.034 15.4 3.2 3 23 1026 1046 1025 1046 0.97 24 29 0.00068 0.073 14.3 2.9 1 23 1053 1076 1053 1076 0.98 25 29 0.00026 0.028 15.6 2.1 1 23 1082 1105 1082 1105 0.96 26 29 0.015 1.6 10.1 0.6 1 23 1111 1134 1111 1134 0.97 27 29 0.00012 0.013 16.7 0.4 1 23 1140 1162 1140 1162 0.97 28 29 4.2e-06 0.00045 21.3 1.2 1 23 1168 1190 1168 1190 0.99 29 29 4.4e-05 0.0047 18.1 5.3 1 23 1196 1218 1196 1219 0.96
Sequence Information
- Coding Sequence
- ATGAGAGAACGCGGAAAAACAGAAAATAAGATCGCAATAAAACTAGAGACGTCAGAGAATTTAGTCGAAAAAGATTCGTCCAAAGTAACGGAAAAGAAACGTTATCAAAGAAGTGCCAGAGCCGAAGCGCGGTTCGTCACAAAGAAGAATGCGAGCTCGATTCTAGAATGTTGGACGCTCTGTCCATTTAGATGGAAAAGAAATCGATTTAAATGCGCCTACTGTGAAGATAACTTCACTGAATGTGCAGAATTGAGAAATCACGTCAGACTTTGCTCGACTCAGCACAGCGTTAAGGATATATACAGCAAATTTAAGGAAATGTCTCTAATAAATATAGATGTAACTGAAGCTAGTTGTAGGATTTGCGCTATGCCCTTTCGAGGGATGAACGAAATGCGTTATCATGTCATAGACCATGGATATGACTTTGATACCTCACATCCAGATGGCGTGTTGCCATTTTTCTTGGACAAGGAGTCTTGGAAGTGCGTCATTTGTCAAGAACAGTTCAATAATTTTCTTAAGCTTTACGAACATATGAATATACACTATCAGCATTATATCTGTGCCACATGTGGAAAGGGTTACATGACAGCGCCTCGCTTGCGTAAACATTCCGAAGTTCATATAACTGGTACTTTTCCGTGCAATAAATGTAGACGAGTTTTTACCATGCGTGCAGCTAGGGATTATCATAAAGCTCACGCTCACGCTAAGGGTCCGCGGTATGAATGTCCTCAATGCAACATGAGATTTGGAGGCTATTATGAAAGAATGAACCATTTGAATGAAGCACACAGAGAAAAGGAAGTGTCTTATAAGTGCGCCCATTGTGAGTTGTCGTTTAAAACGAGTGGAAAAAGGGCAATACATGTGAGATCGGTCCATTTTCCGCAGCAGCGTAATTTCGCTTGTCCATTCTGTAAATGGTTGTTTAAGACTGGTTATGAGTTAAAAAGACATATGGTCAAACATACAGGTCCCGCTAACGCGGATACACAGGGGATAAAAGTTAGGCGGGTTAGAAAGTTAAAGGAGAATGTATGCGCCAGGCAGATACGTCGACGACGGCGTGCTAACAATGAATTACCAGAGGAATCAGAGAAAAGAATAGCTAAAACGATGATGCGTAGAAATGCGATGACGCTTCTAGAATGTTCAACGGCTTGGGCGTTTCGATGGTTCCAAAGCGCGTTCTATTGCTCCTATTGCGATGCTAAATTTGTGGATCCATTAGTTTTACGCGATCATGTTAATTCTTACCACCTTGCCGATTTACCAACAAAACAGATATTTTCAAAATTGACTGAAAATAATATGATTAAAATAGACGTCTCGAACATACATTGTAGGATGTGTAACTGTAAATTAGAAAACGTAGACTTTCTAAAGAAACACCTACAAAATAGTCATGAAAAAAATTTAAATCAGGATTACAATGATGGTGTACTGCCATTTAAACTAGAATCCGATGGTTTCGAATGCCAAATATGTAGTGCACATTTTACGAGTTTCTGTAAAATTAATGAACACATGAACACGCACTTTAAGAATTACATTTGTGACTCTTGCGGCAAAGCCTTTGTATCAAAATCGCGTTTTAGAACGCATGTTCAGTCACACGAGATTGGCAGCTTTCCTTGTGGAATATGTGATGAAATTTTAGAGACTAGGGTCGCTAGAATGTGTCACAGATCGAGAGTACACAAAAAGGGCATTAGATACACCTGTCCATATTGTCCCGAAGTTTTTACGTCGTATTACGCGAGAGCAAAGCACTTGGTAGACGGTCACGATCAGCAGAAGAGAGAATATGAATGCTTTACTTGCGGCAAATCTTTTGAAACGAGCTGCAAACGCGCCGCTCATACCCGCGATGGCGACACAAGGGAAATAACGGTTAAAATTGAATGGAAAAAAACTCGGAGGGCTACAGAGGATAAAGCGAACGCTGCCCTGATCCTCGAATGTTCGAATGCTGTGGCATTTAGGTGGATGCGCGGGAAATTTATGTGCGCGTACTGTCCTAAAATATGTGCTAATGTTAACGAAATACGTTCACACAGTCAAACGCACGATAAACTAATCATTTTTCAAAAACAAGAAGTCCGAAACTCATTTCCACTAAGAGTTGATATAACAAATCTAAAATGCAGTATATGCGACAGTAGGTTGAAAAACTTAACAGATTTGAAAGATCATTTACAAATAGAACATAGTAAGATTTTTAACGCCAAATTTGGCGATGGTGTTATTCCTTTCATTTTAACCGCTTCTGAATATCGTTGTGTTCATTGCGATACATTGTTCGAAGGTTATATGAATCTATTTAGCCATATGAATGAACATTACCAAAGTTTTGTTTGTTATACTTGTGGCAAAGGATATTCAGCAAAACACAAGTTGAGAGCGCATCAGAAATGTCATGAAACTGGAAGAATTGCATGCCCAAAGTGTGATCTTGTATTTGCAAATCATGTTATCAAAAACAGACACGTTGCTACCGCGCACGGTCCGAAGAAGCGATATCGTTGTCCGATATGTGATGTAACTTTCAAGTCTTGCCATTCGAGATTAAAGCATCTAGACAAAATACACGGACCGATCAAGACGATTAAGTGGAAACGAGGTCGCAGGGTCTATAACGATCATAGAGATAACGCGGCGGTTATATTAGAATTCTCTAACGCCTGTCCTTTTCGGTGGAAACGCGGTGCTTTCGCTTGTTCGCACTGTACGAGAACATTTGGTCAATTTCAGGATCTTTTTAACCACGCACATGAGCACAGTAACCGTCTCGAAGCGATGAGATACGCTCGGCCATACGATAACATGAAAGTTGAAGTTAGCAATTTAAAATGTCTTGTTTGTCAAGAAAGTATGAATGGGCTCGACCAACTCAAGGATCATTTGCTAAACGATCATCAAAAGCCGATCCAGAAAGGCTTGGGATTGGGTGTAACGCCGTTTCTTCTGCAGGGCAAAGATATGCTCTGTACGCATTGCGATGAACGATTCTCATTTTTTTCTACGTTAAACAGTCACATGAATCAACATTATCCAAATAACATTTGTTTTCACTGCGGGAAATCGTTTTCGGCTGCTCATCGTTTAAAAGCTCATCAACTTACTCATGAAACGAATGAAAAGGAGCATAAGTGTTCAAAATGCGATGAAGTCTTCGAAACGAGAACGGCACGACGTAACCACATCAACACAAAACACGCACCAGAAAACCGCTACAAATGTCCATATTGCAATTCCTCCTTTAAAAGGTATTCGGAAAGATTAAAACATTTGAAAGAAATACACAACCAGTGCGTCGAATATCCTTGTCACTTGTGTCCCTCAATTTTCGCTATGTCCGATCAAAGAACTAAACACATAAAAAATGTTCATATAAAACACAAACAATTCCAATGCGACTATTGTCCTAGTAAATTCGTGACTGCTGGCCAGTTGAAGAGTCATTTGGTGAAGCACACTGGAATTCGAGAGTATCAGTGTACCGTTTGTAAAAAGAGCTATGCAAGAGTTAGAACATTAAAGGAACATATGCGTATACACAATAACGATAGGCGTTTTGTATGCGAGTATTGTAATAATGCCTTCATTCAGAAGTGCAGTCTTAAAAGCCACATGCGAACACATCATCCTACTGTAGAACCTACCAAGATTCATACTTAA
- Protein Sequence
- MRERGKTENKIAIKLETSENLVEKDSSKVTEKKRYQRSARAEARFVTKKNASSILECWTLCPFRWKRNRFKCAYCEDNFTECAELRNHVRLCSTQHSVKDIYSKFKEMSLINIDVTEASCRICAMPFRGMNEMRYHVIDHGYDFDTSHPDGVLPFFLDKESWKCVICQEQFNNFLKLYEHMNIHYQHYICATCGKGYMTAPRLRKHSEVHITGTFPCNKCRRVFTMRAARDYHKAHAHAKGPRYECPQCNMRFGGYYERMNHLNEAHREKEVSYKCAHCELSFKTSGKRAIHVRSVHFPQQRNFACPFCKWLFKTGYELKRHMVKHTGPANADTQGIKVRRVRKLKENVCARQIRRRRRANNELPEESEKRIAKTMMRRNAMTLLECSTAWAFRWFQSAFYCSYCDAKFVDPLVLRDHVNSYHLADLPTKQIFSKLTENNMIKIDVSNIHCRMCNCKLENVDFLKKHLQNSHEKNLNQDYNDGVLPFKLESDGFECQICSAHFTSFCKINEHMNTHFKNYICDSCGKAFVSKSRFRTHVQSHEIGSFPCGICDEILETRVARMCHRSRVHKKGIRYTCPYCPEVFTSYYARAKHLVDGHDQQKREYECFTCGKSFETSCKRAAHTRDGDTREITVKIEWKKTRRATEDKANAALILECSNAVAFRWMRGKFMCAYCPKICANVNEIRSHSQTHDKLIIFQKQEVRNSFPLRVDITNLKCSICDSRLKNLTDLKDHLQIEHSKIFNAKFGDGVIPFILTASEYRCVHCDTLFEGYMNLFSHMNEHYQSFVCYTCGKGYSAKHKLRAHQKCHETGRIACPKCDLVFANHVIKNRHVATAHGPKKRYRCPICDVTFKSCHSRLKHLDKIHGPIKTIKWKRGRRVYNDHRDNAAVILEFSNACPFRWKRGAFACSHCTRTFGQFQDLFNHAHEHSNRLEAMRYARPYDNMKVEVSNLKCLVCQESMNGLDQLKDHLLNDHQKPIQKGLGLGVTPFLLQGKDMLCTHCDERFSFFSTLNSHMNQHYPNNICFHCGKSFSAAHRLKAHQLTHETNEKEHKCSKCDEVFETRTARRNHINTKHAPENRYKCPYCNSSFKRYSERLKHLKEIHNQCVEYPCHLCPSIFAMSDQRTKHIKNVHIKHKQFQCDYCPSKFVTAGQLKSHLVKHTGIREYQCTVCKKSYARVRTLKEHMRIHNNDRRFVCEYCNNAFIQKCSLKSHMRTHHPTVEPTKIHT
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01080905; iTF_01506541; iTF_01080082; iTF_01507417;
- 90% Identity
- -
- 80% Identity
- -