Basic Information

Insect: Megathymus ursus
Gene Symbol: -
Assembly: GCA_003671415.1
Location: PDGT01000024.1:2499030-2516843[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 7.8e-05 0.0059 17.3 1.5 1 23 434 456 434 456 0.96

2 20 0.0027 0.21 12.5 0.6 1 20 462 481 462 484 0.94

3 20 9.9e-05 0.0076 17.0 5.3 3 23 505 525 503 525 0.97

4 20 3.3e-05 0.0025 18.5 4.6 1 23 531 553 531 553 0.99

5 20 3.3e-05 0.0025 18.5 5.3 1 23 559 581 559 581 0.97

6 20 1.6e-05 0.0012 19.5 7.2 1 23 587 609 587 609 0.97

7 20 6.4e-07 4.9e-05 23.9 2.9 1 23 615 637 615 637 0.97

8 20 9.2e-05 0.007 17.1 6.7 1 23 643 665 643 665 0.97

9 20 9.1e-05 0.0069 17.1 6.5 1 23 671 693 671 693 0.97

10 20 4.4e-07 3.3e-05 24.4 1.9 1 23 699 721 699 721 0.98

11 20 4.5e-05 0.0034 18.1 7.9 1 23 727 749 727 749 0.98

12 20 7.1e-06 0.00054 20.6 6.6 1 23 755 777 755 777 0.98

13 20 1.5e-05 0.0012 19.5 4.3 1 23 783 805 783 805 0.98

14 20 9.5e-05 0.0073 17.1 5.3 1 23 811 833 811 833 0.96

15 20 0.00011 0.0081 16.9 7.5 1 23 839 861 839 861 0.97

16 20 2.8e-06 0.00021 21.9 6.0 1 23 867 889 867 889 0.98

17 20 3.6e-05 0.0028 18.4 10.2 1 23 895 917 895 917 0.97

18 20 2.5e-05 0.0019 18.9 4.5 1 23 923 945 923 945 0.96

19 20 0.0004 0.031 15.1 0.2 1 23 952 974 952 974 0.97

20 20 0.041 3.1 8.8 5.4 1 23 983 1005 983 1005 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	7.8e-05	0.0059	17.3	1.5	1	23	434	456	434	456	0.96
2	20	0.0027	0.21	12.5	0.6	1	20	462	481	462	484	0.94
3	20	9.9e-05	0.0076	17.0	5.3	3	23	505	525	503	525	0.97
4	20	3.3e-05	0.0025	18.5	4.6	1	23	531	553	531	553	0.99
5	20	3.3e-05	0.0025	18.5	5.3	1	23	559	581	559	581	0.97
6	20	1.6e-05	0.0012	19.5	7.2	1	23	587	609	587	609	0.97
7	20	6.4e-07	4.9e-05	23.9	2.9	1	23	615	637	615	637	0.97
8	20	9.2e-05	0.007	17.1	6.7	1	23	643	665	643	665	0.97
9	20	9.1e-05	0.0069	17.1	6.5	1	23	671	693	671	693	0.97
10	20	4.4e-07	3.3e-05	24.4	1.9	1	23	699	721	699	721	0.98
11	20	4.5e-05	0.0034	18.1	7.9	1	23	727	749	727	749	0.98
12	20	7.1e-06	0.00054	20.6	6.6	1	23	755	777	755	777	0.98
13	20	1.5e-05	0.0012	19.5	4.3	1	23	783	805	783	805	0.98
14	20	9.5e-05	0.0073	17.1	5.3	1	23	811	833	811	833	0.96
15	20	0.00011	0.0081	16.9	7.5	1	23	839	861	839	861	0.97
16	20	2.8e-06	0.00021	21.9	6.0	1	23	867	889	867	889	0.98
17	20	3.6e-05	0.0028	18.4	10.2	1	23	895	917	895	917	0.97
18	20	2.5e-05	0.0019	18.9	4.5	1	23	923	945	923	945	0.96
19	20	0.0004	0.031	15.1	0.2	1	23	952	974	952	974	0.97
20	20	0.041	3.1	8.8	5.4	1	23	983	1005	983	1005	0.99

Sequence Information

Coding Sequence: ATGAATCAAGAGCATCACAATATCAATACGGGTGGTGGCCAGCCCCCTGGCAATTCGGAGtCGCAGAACCAAAGAGTGCAATCTGCGCAACAGCAACAACAAGGCACGAATCTGCCTCCGACAACGTCAGCGACCGACTTGAGAGTTAACTCGGCAGCCGTAAACGTTGCATTGTCGAGCGTTGCCAAGTATTGGgtgtttacaaatttattccCTGGACCATTACCACAAGTTTCCGTATATAATTTACCTTCAAATGCTAGAATAGAAAATGGAAAACCAGtacagGACCTCGGTCAGACACATGGTATACTCAATGGTGATCCGAATATCATACTTGGACACCATGCTGGTCAGTCACAGGTTACTGTATCAGCAGCAGGCCAGCAGATACCTGTTCCACAAATTATTGCAACCCAATCTGGACAGACCCATGAAGCACTTGTGACACATGGTCAACAGCAGGAGCTAACAACACAGCAGGCTTCAAGCGGGGCTCAGGTGACAGTGAGCGGGAGTCAGGGCTCCCACCAGCAGGTACCCAATAACAGGGTCGAGTTTGTACAACACCATAACATTGATATGGTAAATCATGTGGGCCATCATTCACAACAACAACATTTACTTCAACAACAACTTTTGGCGGCTTCACGACCAGACCACGCCAATCAACagATCCAATTGACCGTCAGTGAAGATGGTATTGTCACGGTGGTTGACCCCGGTGCAGGCAAACTAGTAGACAAAGAGGATCTTCATGAGACTATCAAGTTGCCTACAGACCACACACTCACCGTGCATCAGTTGCAACAGATTGTAGGGCATCATCAGGTGATAGACAGCGTGGTACGGATAGAGCAGGCGACCGGGGAGCCGGCGAACATCCTGGTGACGCAGAATCCGGACGGTACCACGTCGATCGAAACGAGTGCCGCGGACCCGCTCGCCATCGTCAAGGACGAGAAGTCAGTCGCCAAGATCGACGCGGCGCAGTTCGCCATACCTGCCGATATTAAGGAGATTAAAGATTTAAAGAGTGTCGGAGCAATGGGAATGGAAGGTGCGGTAGTGAAGATCTCCGCTGGCGCCACGGAACACGATCTACACGCCATGTACAAAGTGAATGTTGAAGATCTGTCTCAACTGCTCGCCTACCACGAAGTGTTCGGAAAACTTAATACAGAgggtcaacaacaacaacaacagcaacagcaaCAATCATCTAAGGTTATTACTGAAGTTGAAACAGAAGCCAGTACAAGTGCAGCGATGTCCGAAGCGGACTCCTCTCCCGGCCACCACGCTTGTGATATATGCGGAAAGATATTCCAATTCCGTTACCAGCTTATTGTTCATAGGCGATACCATGGAGAAAGCAAACCATATACGTGTCAAGTGTGTGGTTCCGCATTCGCCAATCCTGTAGAATTATCAAGACATGGAAAATGTCATTTGGCGGGCGACCCGGCCGAAAGACAAACAAAAAGATTGACACAAGACAAACCCTATGGTTGCTCCACTTGTCATAAAACTTTCTCCAGAAAGGAGCATCTCGACAACCACGTGCGGAGTCACACCGGGGAAACACCTTACAGGTGCCAGTACTGCGCGAAGACATTCACTCGCAAAGAGCACATGGTGAACCACGTGAGAAAGCACACAGGCGAGACACCGCACCGCTGCGACATCTGTAAGAAAAGCTTCACGCGCAAGGAGCACTTCATGAACCACGTCATGTGGCACACGGGTGAAACGCCGCACCATTGTCAAATATGCGGCAAGAAGTATACTAGGAGGGAGCATTTAGTGAACCATATGAGGTCACATACAAACGATACCCCGTTCCGCTGCGAACTGTGCGGCAAGTCGTTCACGAGAAAGGAACACTTCACCAATCACATATTGTGGCACACGGGTGAAACCCCTCACCGATGTGACTTCTGCTCGAAGACGTTCACGCGCAAGGAACACCTGTTGAACCACGTTCGTCAGCACACCGGTGAGTCGCCGCACCGGTGCAACTTCTGCTCCAAGTCATTCACGCGCCGCGAGCATCTCGTCAACCACGTCCGACAACATACCGGCGAGACTCCCTTCCAGTGCGGATACTGTCCGAAGGCGTTCACTAGGAAAGACCACTTAGTGAACCACGTGCGTCAGCATACGGGCGAGTCGCCGCACAAGTGTTCGTTCTGCACTAAGTCGTTCACGCGCAAGGAACACCTCACGAACCACGTTCGACAACACACGGGCGAGTCGCCGCACAGGTGTACATACTGCGCCAAATCCTTTACTAGGAAAGAACATCTCACCAATCATATCAGACAACACACGGGTGAAACGCCGCACAAGTGCACGTTATGTCCGCGCGCGTTCTCGCGGAAGGTGCACCTCAACAACCATGTGCGGCAGCACACGGGCGATACGCCGCACGCGTGCACCTTCTGCTCTAAAAGCTTCACGCGCAAGGAGCACCTCGTCAACCACGTGAGGCAACACACGGGCGAAACTCCGTTCAAGTGTACATTCTGTACAAAGTCGTTCTCGCGGAAGGAACACCTCACGAACCACGTTCACCTACATACGGGTGAAACACCGCACAAGTGTCCGTTCTGCACCAAGACCTTCTCACGCAAGGAGCATCTTACCAACCATGTTAGGATACATACAGGTGAATCCCCTCATCGTTGCGAGTTCTGTCACAAGACATTCACCCGCAAGGAGCACCTAACGAATCACATGAAACAACACACAGGCGATACGCCACACGCTTGTAAGGTGTGTCTTAAACCCTTTACCAGGAAAGAACACCTCAGTACCCATATGAGATCGCACAGTTGCGGTGAAAGGCCATTCAGCTGCGGCGAGTGCGGAAAATCGTTCCCGTTAAAGGGTAACCTAATCTTCCACGAGAGATCGCACAATAAATCTAGTAGTTCTAGGCCTTTCCGATGTGATGTCTGTTCCAAAGACTTCATGTGTAAAGGGCATCTAGTGTCACACAGGCGGACGCATGCGGAGGCCGGCGACGCCGTCAGCACCGAACCGGTGGCCGAGGGCGAGGACTGCGGTGACTGTACCAAGTGTGAGAAGGATGCGCCCGACCGACCCGAGCGGAAACACGACGTCAGGCCACCTTCAGAAAACAGACCTACAGAAAGCAATACAGCACAAACACAACAAACCAATACAGCTGTGATGCAAATCACCAGTcaaCAAGTTAGAACGGTTGCAGCGAGCAACGCGACGAGTGTAGCGACCGCTACGTTCACGCACACAGCGAGCCCGCAGCATCACACTGGTGCAGCTATAGCCCACCATCCAGTTACCGTCAACTACTAA
Protein Sequence: MNQEHHNINTGGGQPPGNSESQNQRVQSAQQQQQGTNLPPTTSATDLRVNSAAVNVALSSVAKYWVFTNLFPGPLPQVSVYNLPSNARIENGKPVQDLGQTHGILNGDPNIILGHHAGQSQVTVSAAGQQIPVPQIIATQSGQTHEALVTHGQQQELTTQQASSGAQVTVSGSQGSHQQVPNNRVEFVQHHNIDMVNHVGHHSQQQHLLQQQLLAASRPDHANQQIQLTVSEDGIVTVVDPGAGKLVDKEDLHETIKLPTDHTLTVHQLQQIVGHHQVIDSVVRIEQATGEPANILVTQNPDGTTSIETSAADPLAIVKDEKSVAKIDAAQFAIPADIKEIKDLKSVGAMGMEGAVVKISAGATEHDLHAMYKVNVEDLSQLLAYHEVFGKLNTEGQQQQQQQQQQSSKVITEVETEASTSAAMSEADSSPGHHACDICGKIFQFRYQLIVHRRYHGESKPYTCQVCGSAFANPVELSRHGKCHLAGDPAERQTKRLTQDKPYGCSTCHKTFSRKEHLDNHVRSHTGETPYRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHFMNHVMWHTGETPHHCQICGKKYTRREHLVNHMRSHTNDTPFRCELCGKSFTRKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCNFCSKSFTRREHLVNHVRQHTGETPFQCGYCPKAFTRKDHLVNHVRQHTGESPHKCSFCTKSFTRKEHLTNHVRQHTGESPHRCTYCAKSFTRKEHLTNHIRQHTGETPHKCTLCPRAFSRKVHLNNHVRQHTGDTPHACTFCSKSFTRKEHLVNHVRQHTGETPFKCTFCTKSFSRKEHLTNHVHLHTGETPHKCPFCTKTFSRKEHLTNHVRIHTGESPHRCEFCHKTFTRKEHLTNHMKQHTGDTPHACKVCLKPFTRKEHLSTHMRSHSCGERPFSCGECGKSFPLKGNLIFHERSHNKSSSSRPFRCDVCSKDFMCKGHLVSHRRTHAEAGDAVSTEPVAEGEDCGDCTKCEKDAPDRPERKHDVRPPSENRPTESNTAQTQQTNTAVMQITSQQVRTVAASNATSVATATFTHTASPQHHTGAAIAHHPVTVNY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00795879;
90% Identity: iTF_00971540; iTF_01359950; iTF_00288224; iTF_00025394; iTF_01153175; iTF_01438226; iTF_01439222; iTF_01082651; iTF_00795879;
80% Identity: iTF_00971540;