Basic Information

Insect: Mamestra configurata
Gene Symbol: IKZF1
Assembly: GCA_002192655.2
Location: NDFZ01005496.1:1452797-1460814[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 2.6 2.5e+02 3.0 0.9 1 23 54 77 54 77 0.94

2 17 0.072 6.8 7.9 4.1 1 23 84 107 84 107 0.97

3 17 0.17 16 6.7 3.4 2 22 435 455 434 455 0.95

4 17 0.072 6.8 7.9 2.6 1 23 552 574 552 574 0.95

5 17 0.5 47 5.3 0.3 2 23 711 732 710 732 0.96

6 17 0.00095 0.09 13.9 0.5 2 23 812 833 811 833 0.96

7 17 0.11 10 7.4 0.3 1 23 841 863 841 863 0.97

8 17 4.2 4e+02 2.4 2.6 1 23 899 921 899 921 0.93

9 17 0.0002 0.019 16.0 4.0 1 23 929 951 929 951 0.99

10 17 0.7 66 4.8 2.2 1 23 1035 1057 1035 1057 0.97

11 17 0.81 77 4.6 1.8 1 20 1115 1134 1115 1137 0.92

12 17 0.55 52 5.2 0.6 1 23 1236 1258 1236 1258 0.94

13 17 0.0046 0.43 11.7 1.1 1 23 1264 1286 1264 1286 0.96

14 17 0.0056 0.53 11.4 2.6 1 23 1376 1398 1376 1398 0.97

15 17 0.00014 0.013 16.5 1.4 1 23 1404 1426 1404 1426 0.99

16 17 0.7 66 4.8 2.7 1 23 1516 1538 1516 1538 0.96

17 17 0.0082 0.78 10.9 5.6 1 23 1549 1571 1549 1571 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	2.6	2.5e+02	3.0	0.9	1	23	54	77	54	77	0.94
2	17	0.072	6.8	7.9	4.1	1	23	84	107	84	107	0.97
3	17	0.17	16	6.7	3.4	2	22	435	455	434	455	0.95
4	17	0.072	6.8	7.9	2.6	1	23	552	574	552	574	0.95
5	17	0.5	47	5.3	0.3	2	23	711	732	710	732	0.96
6	17	0.00095	0.09	13.9	0.5	2	23	812	833	811	833	0.96
7	17	0.11	10	7.4	0.3	1	23	841	863	841	863	0.97
8	17	4.2	4e+02	2.4	2.6	1	23	899	921	899	921	0.93
9	17	0.0002	0.019	16.0	4.0	1	23	929	951	929	951	0.99
10	17	0.7	66	4.8	2.2	1	23	1035	1057	1035	1057	0.97
11	17	0.81	77	4.6	1.8	1	20	1115	1134	1115	1137	0.92
12	17	0.55	52	5.2	0.6	1	23	1236	1258	1236	1258	0.94
13	17	0.0046	0.43	11.7	1.1	1	23	1264	1286	1264	1286	0.96
14	17	0.0056	0.53	11.4	2.6	1	23	1376	1398	1376	1398	0.97
15	17	0.00014	0.013	16.5	1.4	1	23	1404	1426	1404	1426	0.99
16	17	0.7	66	4.8	2.7	1	23	1516	1538	1516	1538	0.96
17	17	0.0082	0.78	10.9	5.6	1	23	1549	1571	1549	1571	0.98

Sequence Information

Coding Sequence: ATGCTACAGCAGATGTCCTCGTCGCCGCGCGCACAAGTCGGCGAGGTCGCGACTATCGTGCGCCACCTTGAAGGCCGCGTCTGCGGCGACGTTTCTTCGGAGGCTTCTTCGGACGCCGCCGAAGATTTCGAATTACCACAGTGCAAGATAAGGAGGAATTATAATTGCACCAAGTGCACGTTCTATACGCAGAACCCGCGCGCTTATCTCGTCCACACGCGTGACGCTCACTTCGTCAGACTCAAGATTTACGATTGTCCACACTGTGTTTACGCCTCGAGACATCATCAAAAACTTATAAGACACGTCAAAATGGTTCACGGAggaacaaaacaaacttctacGACTGCTAAAGTGGAAGAGCTATCACCTCCCCCCAACGATAACATGGAGCCAGCAGAGCGCATTGAAGACATGCTTGAGGAAGTCGAGGACTGCGAGGAGATGATGATGGAAGTAGATGAGGACTCCATGGACCAACCTGATGATGTCGACGGTGACGGCGACCAAAGTGTAGACTTCGGATCGCCCTATCGGAGAGCACAGTCTGACGGTGCACGAAATGAATCATCACACACCGGCNNNNNNNNNNNNNNNNNNNNNNNNNNNNCACCGGCAACGGGCCAATCGCTGCCGAGTCGCCGCCGCAACCGGGTGGGCGCCAGCGACACGGTTATCGCGGAGTACGACGCGGCGAGCGCGTTGCTCCCCAAGGAGGAAGAAGGGAGCGGCGACTCGCGGTCCTCACACTCGGTCTCGGACATGGGTCTCCAATACGCAGAGAGAGAACTAGTCAGTTGCAAAAGTGATTCCAACGACGGTACAGCTTCTGATGCAATCACCAACCGAAAGGAAACTTCGCAAGATGGATACAACCTTTCACCAACTCATAGCGCAGACGAGAAGCTCCAAAAACAATGCAGGAAGATTCCCAGGCCAATACCACAACTCATACCGCTGAATTCATCGACACCAAACCAAAAACAAACCTGTTCTGGTGAACCACCACAGAAAAAGTTCAAGGAATCTTTACCCGACAGCGATGATGTATCTGCTGAAAATACTCTCTTACCAGCAAACCCATCGATAAAAGAGACTGCAGGTCGAAAGAAAAATGAATCATTTTTCGACAGATTAAAAGAAAGACTGCTTACAGAAACAGGCGAAGAAGGTTCACTAATATGTAAGATCTGTGGATTTGAAAGTAAATGCCTATCGGAACATTCTGTACATGAGAAAAATTGTTCTCCACAAACAAATCGGATCAATGCAAACACGTCGCTTAAAAGTTTAAGTTCCACTCGATGCCAGAATTGTAGACACAGGTGCAAGTCTAGTGCAGACTTGTACATCCACATGCAAACTTGCGTTAAAAGCGACTCCGCCGACAATGAAACCTCTATCAAAATTGATAGTAGTAATGATGGAGTCATTCCAATCCATGAAACAGAGACTGAGCCTCATCCAATGGAAAACGTCGTTTTCGTTTGGAACAATATTAACCACGACCCTAACAAGTTTGATGTACCCCTagacataaatataaatgatgatTCCACTCTACCAGAAATGCATCGAGGTTTTGATGCTGAGATTGTTGATGATAATGAAAGCATGAATTTGTCGCCGAGTCAAGCTATTGGAAGGAAGGTATTTAAATGTCCAcattgtccattcttctccacaACAGCATCCAGATTTCATGTTCATATCGTCGGTCACTTAAACAAGAAACCGTTTGAATGCTCCCTCTGCAAATATAAATCTAATTGGAGATGGGATATCACCAaacatattaaattgaaatccGCGAGGGATCCCGACCATAATGAAGCAAAAGTACTTATGACCGATGAAACAGGAAGAAGAAACTATAGCAAATACAACAAATTCTTAGCAATGCCTGTTTTAAATGAACATGGTGAAAATGAGTTCCATTACCTGGATCCTAACACTGCAGTCGACAGCACGATGGAAATTGATGAATCATTTAATGAAATATCCGACGTTATGAATGTACAATTTGAAATGCAACCGCTTAACTTACAGACACAACACATTGAAGATAATTACAACTTTATTGATAATAGAGGTCTCAACGATATGAAGAAGCCCAAAAAGACGTTATGGAAatgtaaaaaatgtaattacaaagatCCCTCAAAAGAAGCGCTATTAGAACATGTTCGTGAACACTCCAGATCGGAAGGCTTCCATGAAGAGCCAAATAAACCACCTATTAAGAAACCTGAAAACAATACTCCCGACCCAGCCGATCTGGCGTACCGTTGTGGTCATTGCAATCAGCTATCTAATTGGAAACATGTCATCCAGCGCCATTGCCGATTAAAACACGATGGAGTGATCAAAGTGATAACTACAGTTAAACCAAAACCTGATCCACCGATGAACATCAATGAGATCAACATTGATACTTGCAACAAGTGTCCGTACAGGACGAGTGACAAGAAGCTACTCATCGCTCATTTACAACAGCATCAGCCCTCGCCGAATTCTATTTTCAAGTGCTACTTCTGTCCGTTCTTCGTGAAGGATGAGCCAGAATTAATTCAACATCTGCTCCTGCACGGTATCACCGACCCAGAAGATTACATCGCAAAAGCAATGGGAACTAAATCCCCAGGACCAGAACCGCAAGTTCCTGTTACTACGTCATTAAACTCCACAAAGCGCCACAAATGCATAGAATGTCCATACGAAACAAACAGTAAGTCACAATTCATGTACCACGAACAATTTCATCGACTGCCGGCGGATACGCCATACAAATGTCCAGAATGCAACTACAGCGTTTCTAAGAGACACCTGCTGCACCAGCATCTGCGAGTCCACGGCATCGCAACCAAAAGAATTGAAACCGAGGCCGAATTAGAAGCATCAACCTCCACCCAAAACAAGATGGATAAAACGGACTCCCATATTAATCTTGATGAAATACCATTTGTCTGGGTTTCAGCCAAGAATGAGTTTCATAAAATGTACAAGTGCCGATACTGTTCATACGTTAATgctataaaatgcaaaataccaAATCATGAAAAAATTCATTGCATCGTACTCGAAAACAATGATACAACTATTTACAAATGTTTGGAATGCAAATTCACGTGTGATAAACCCGGCAGACTCGCAGAGCATTCCAAAAATCATGCAGAAATATATGGTCGCATTTATTGTCCCGTCGAACATGATGTGCCCGATGAAGAACAAATCACAAAATTGAGAAAAGTTatagaaattgaaaaattagCAAATCCCGAAAGTACCACAACCTCAAAAGATGAAGGCAATACGCAAGAAAAtggagaaataaaattattatatttttgtcaaaagtgTCCAGCAAGATTTTTTGATGACGTCCAACTCGAGGCTCATGAAAAATGTCATCAATCAAATCATGGTTTAACATTGCCCAACAAATGTAAAAGTTGTGACTTTTCGGTGACCGAAGATTTAGAATTAGCGGCACATTTTTCTGTCCACACAGATACatatcacacaaaaacaaagatgCTTAAATTTATTCACAACTCACATCGTTTACACAGGCCACCCGTGCTCGAGTTGGTTCACTGGCCAACGACTTCTGAGATTACGTGGGTAGCCACTGGGCCGAGCAAAGCTGAAAATATTGAAAGCCCTTTGAAAAAAACGAATGATTCAAAACACGTgccaaaacaatatttttgcagACAATGTCCAGCGAAGTTTTTCAAAGGTTCCGCGCTTTCCTACCACATGGGGCTGCATGGGGGTGAAGGCGAGCACAAGTGCAAAAAGTGCAACTACGCCGTGAAGAACATTGGGAATCTAGCCAAACATGAATTACTTCACGATAATGACAACAAGGGTACAAGTTGCGACTATGAATCCGGCGACGATatggattataaaaatattccattGTCAGGCACAGATTTGTTCCAGAGGAAGACTGAGGCTCAGAAAAGAGTTTTAACGGATAAAGATAAGTTAGTTAAGCCGAACGATCATTTTCCGCCTGTCCTACAAGCTGATCCCCAGTTCGGTTATCTAATGCACGGTAATCCGGAATTCATATATCCCACCTACTTGAAAAATGGTCGCCAAAAAGAAAAGCGATACAAATGCCACAAGTGTCCGTCAGCCTTTGAGAAAAGAGAACAATATAAGATTCATTTATCATTGCACGGCTCCAAGCAAAGATATAAATGTGAGTTGTGTGATTATTCCGTGAAATATTACGCCAATTACGTTCAACATATGCGAAAACATCAAATGAACGATGAAGCTCAAGCTGAAAGGAAAAAAGGTAACGATTTTACAGAATCAGAACATCAAGAAGACGTAAAGCAAGACGACAGCAGCGATAACattaaacttgcaataaaaacTATGCCAAAAGGAGCTGCTAAGAGTGACTTTCAACAATTCTCAATTAGCGACCAACAAACGCTCAGGCTGCTGCAGAGGAGACGGTCAATGAATAATTCTGGAAACCACAACAGTTCTGAAACTTCGCCAATCAAAGAGCGCAAAATGCACATGTGTCTATTATGTCCCTACACTAATCAACGTCAAGATTCTTTAAGCAATCATTACAGGAGGCACGGTGACACCGATATCCTGAACGGAGGCAGTCATAAATGTTCTCATTGCGACCTAGTGGTTGTTCAGTCGCATTTCCTTCGAGAACATCTCAAGACACACTTCAACTACCACAAAACTCTTATTCCTGAATGTTTTGTGGCTAACGAAGCTGTTAGTTTTACTATAACCAAGTTGGATGAAGACGGTGAATCAGTTGATCTCAAATTAGATGTGCAGAACAAGAGTTATGCATGTAACGATGAAAAGatatttgtgaaaattaaaactggaGAACTAttggtagaataa
Protein Sequence: MLQQMSSSPRAQVGEVATIVRHLEGRVCGDVSSEASSDAAEDFELPQCKIRRNYNCTKCTFYTQNPRAYLVHTRDAHFVRLKIYDCPHCVYASRHHQKLIRHVKMVHGGTKQTSTTAKVEELSPPPNDNMEPAERIEDMLEEVEDCEEMMMEVDEDSMDQPDDVDGDGDQSVDFGSPYRRAQSDGARNESSHTGXXXXXXXXXXPATGQSLPSRRRNRVGASDTVIAEYDAASALLPKEEEGSGDSRSSHSVSDMGLQYAERELVSCKSDSNDGTASDAITNRKETSQDGYNLSPTHSADEKLQKQCRKIPRPIPQLIPLNSSTPNQKQTCSGEPPQKKFKESLPDSDDVSAENTLLPANPSIKETAGRKKNESFFDRLKERLLTETGEEGSLICKICGFESKCLSEHSVHEKNCSPQTNRINANTSLKSLSSTRCQNCRHRCKSSADLYIHMQTCVKSDSADNETSIKIDSSNDGVIPIHETETEPHPMENVVFVWNNINHDPNKFDVPLDININDDSTLPEMHRGFDAEIVDDNESMNLSPSQAIGRKVFKCPHCPFFSTTASRFHVHIVGHLNKKPFECSLCKYKSNWRWDITKHIKLKSARDPDHNEAKVLMTDETGRRNYSKYNKFLAMPVLNEHGENEFHYLDPNTAVDSTMEIDESFNEISDVMNVQFEMQPLNLQTQHIEDNYNFIDNRGLNDMKKPKKTLWKCKKCNYKDPSKEALLEHVREHSRSEGFHEEPNKPPIKKPENNTPDPADLAYRCGHCNQLSNWKHVIQRHCRLKHDGVIKVITTVKPKPDPPMNINEINIDTCNKCPYRTSDKKLLIAHLQQHQPSPNSIFKCYFCPFFVKDEPELIQHLLLHGITDPEDYIAKAMGTKSPGPEPQVPVTTSLNSTKRHKCIECPYETNSKSQFMYHEQFHRLPADTPYKCPECNYSVSKRHLLHQHLRVHGIATKRIETEAELEASTSTQNKMDKTDSHINLDEIPFVWVSAKNEFHKMYKCRYCSYVNAIKCKIPNHEKIHCIVLENNDTTIYKCLECKFTCDKPGRLAEHSKNHAEIYGRIYCPVEHDVPDEEQITKLRKVIEIEKLANPESTTTSKDEGNTQENGEIKLLYFCQKCPARFFDDVQLEAHEKCHQSNHGLTLPNKCKSCDFSVTEDLELAAHFSVHTDTYHTKTKMLKFIHNSHRLHRPPVLELVHWPTTSEITWVATGPSKAENIESPLKKTNDSKHVPKQYFCRQCPAKFFKGSALSYHMGLHGGEGEHKCKKCNYAVKNIGNLAKHELLHDNDNKGTSCDYESGDDMDYKNIPLSGTDLFQRKTEAQKRVLTDKDKLVKPNDHFPPVLQADPQFGYLMHGNPEFIYPTYLKNGRQKEKRYKCHKCPSAFEKREQYKIHLSLHGSKQRYKCELCDYSVKYYANYVQHMRKHQMNDEAQAERKKGNDFTESEHQEDVKQDDSSDNIKLAIKTMPKGAAKSDFQQFSISDQQTLRLLQRRRSMNNSGNHNSSETSPIKERKMHMCLLCPYTNQRQDSLSNHYRRHGDTDILNGGSHKCSHCDLVVVQSHFLREHLKTHFNYHKTLIPECFVANEAVSFTITKLDEDGESVDLKLDVQNKSYACNDEKIFVKIKTGELLVE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01231174;
90% Identity: iTF_00952296; iTF_00974240; iTF_00852296; iTF_00300769; iTF_00851278; iTF_00772479;
80% Identity: -