Basic Information

Insect: Hecatera dysodea
Gene Symbol: IKZF1
Assembly: GCA_905332915.1
Location: HG995292.1:7828522-7836027[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 3.4 3.7e+02 3.0 0.9 1 23 54 77 54 77 0.94

2 20 0.094 10 7.9 4.1 1 23 84 107 84 107 0.97

3 20 5.5 5.9e+02 2.3 4.0 1 23 192 214 192 214 0.96

4 20 0.0019 0.2 13.2 1.0 2 23 220 241 219 241 0.97

5 20 2.3 2.4e+02 3.5 1.4 1 23 247 269 247 270 0.94

6 20 0.23 24 6.7 3.4 2 22 500 520 499 520 0.95

7 20 0.094 10 7.9 2.6 1 23 617 639 617 639 0.95

8 20 0.65 70 5.2 0.3 2 23 776 797 775 797 0.96

9 20 0.0012 0.13 13.8 0.5 2 23 877 898 876 898 0.96

10 20 0.14 15 7.3 0.3 1 23 906 928 906 928 0.97

11 20 0.1 11 7.8 3.6 1 23 964 986 964 986 0.95

12 20 0.00026 0.028 15.9 4.0 1 23 994 1016 994 1016 0.99

13 20 0.26 28 6.5 1.8 1 23 1100 1122 1100 1122 0.97

14 20 1.2 1.3e+02 4.4 1.5 1 20 1180 1199 1180 1202 0.92

15 20 0.0076 0.82 11.3 0.8 1 23 1301 1323 1301 1323 0.96

16 20 0.0059 0.63 11.7 1.1 1 23 1329 1351 1329 1351 0.96

17 20 0.0073 0.79 11.4 2.6 1 23 1441 1463 1441 1463 0.97

18 20 0.00018 0.02 16.4 1.4 1 23 1469 1491 1469 1491 0.99

19 20 0.91 97 4.8 2.7 1 23 1581 1603 1581 1603 0.96

20 20 0.011 1.1 10.8 5.6 1 23 1614 1636 1614 1636 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	3.4	3.7e+02	3.0	0.9	1	23	54	77	54	77	0.94
2	20	0.094	10	7.9	4.1	1	23	84	107	84	107	0.97
3	20	5.5	5.9e+02	2.3	4.0	1	23	192	214	192	214	0.96
4	20	0.0019	0.2	13.2	1.0	2	23	220	241	219	241	0.97
5	20	2.3	2.4e+02	3.5	1.4	1	23	247	269	247	270	0.94
6	20	0.23	24	6.7	3.4	2	22	500	520	499	520	0.95
7	20	0.094	10	7.9	2.6	1	23	617	639	617	639	0.95
8	20	0.65	70	5.2	0.3	2	23	776	797	775	797	0.96
9	20	0.0012	0.13	13.8	0.5	2	23	877	898	876	898	0.96
10	20	0.14	15	7.3	0.3	1	23	906	928	906	928	0.97
11	20	0.1	11	7.8	3.6	1	23	964	986	964	986	0.95
12	20	0.00026	0.028	15.9	4.0	1	23	994	1016	994	1016	0.99
13	20	0.26	28	6.5	1.8	1	23	1100	1122	1100	1122	0.97
14	20	1.2	1.3e+02	4.4	1.5	1	20	1180	1199	1180	1202	0.92
15	20	0.0076	0.82	11.3	0.8	1	23	1301	1323	1301	1323	0.96
16	20	0.0059	0.63	11.7	1.1	1	23	1329	1351	1329	1351	0.96
17	20	0.0073	0.79	11.4	2.6	1	23	1441	1463	1441	1463	0.97
18	20	0.00018	0.02	16.4	1.4	1	23	1469	1491	1469	1491	0.99
19	20	0.91	97	4.8	2.7	1	23	1581	1603	1581	1603	0.96
20	20	0.011	1.1	10.8	5.6	1	23	1614	1636	1614	1636	0.98

Sequence Information

Coding Sequence: ATGCTACAGCAGATGTCCTCGCCGCCGCGCGCACAAGTCGGCGAGGTCGCGACTATCGTGCGCCACCTTGAAGGCCGCGTCTGCGGCGACGTGTCTTCGGAGGCCTCCTCGGACGCCGCCGAAGATTTCGAATTACCACAGTGCAAGATAAGGAGGAATTATAATTGCACCAAGTGCACGTTCTATACGCAGAACCCGCGCGCTTATCTCGTCCACACGCGTGACGCTCACTTCGTCAGACTCAAGATTTACGATTGTCCACACTGTGTTTACGCCTCGAGACATCATCAAAAACTTATAAGGCACGTCAAAATGGTTCACGGAGGAACAAAACAGGCCTCTACCACTTCTGCGAAAGTGGAAGAGCTATCACCTCCCCCCAACGATAACATGGAGCCGGCAGAGCGCATTGAAGACATGCTTGAAGAAGTCGAGGACTGCGAGGAAATGATGATGGAAGTGGATGAGGACTCCATGGACCGGCTTGATGATGTGGACGGCGACGGCGACCAAAGTGTAGACTTCGAATCGCCCTACCGGAGGGCACGTCTGTCAAAAGCTAAGGGCAAATTCTTCTCATGCGATAAGTGTAACTATGTCACCCACATAAGAGCTAGATTCACAAAGCACGTCAAGTATCATTCAATGCCTATGATCAAGTGTACAATGTGTGATTTTCGAACACCATACAAGTGGAATTTGGACCGTCACATGAAGAACCACGGTGGAAGTGGAAGTTTCAATTGTTCGATGTGCAACTTCACGGCGGACATCAAGCAGAGTCTGACTGTGCACGAAATGAATCATCACACACCGGCAGCGGGCCAATCGCTGCCGAGTCGCCGCCGCAACCGGGTGGGCGCCAGCGACACGGTTATCGCTGAGTACGACGCGGCGAGCGCGTTGCTCCCCAAGGAGGAAGAAGGGAGCGGCGACTCGCGGTCCTCACACTCGGTCTCGGACATGGGTCTCCAATACGCAGAGCGTGAACTAGTCAGTTGCAAAAGTGATTCCAACGACGGTACAGCTTCTGACGCAATCACCAACCGAAAGGAAACTTCGCAAGATGGATACAACCTTTCACCAACCCACAGCGCAGACGAGAAGCTCCAAAAACAGAGCAGAAAGGTTCCAAGGCCAATACCACAACTCATACCGTTAAATTCCTCAACACCTAACCAAAAACAAACTGGTGAACCACCACAGAAAAAGTTCAAGGAGTCTTTACCCGACAGCGATGATGTATCTGCTGAAAATACTCTCTTACCAGCAACCCAATCAATGAAAGAGACAGCAGGTCGAAAGAAAAATGAATCATTTTTCGATAGATTAAAAGAAAGACTGCTTACAGAAACAGGCGAAGAAGGTTCACTTATTTGTAAGATTTGTGGATTTGAAAGTAAATGCTTATCAGAACATTCTGTACACGAGAAAAATTGTTCTCCACAAATGAATCGGATCAATGCAAACACGTCGCTTAAAAGTTTAAGTTCCACTCGATGTCAGAATTGTAGACACAGGTGTAAGTCTAGTGCAGACTTGTACATCCACATGCAAACTTGCGTTAAAGGCGATTCCGCCGACAATGAAAGCTCTATCAAAATTGACAATAGTAATGATGAAGTAATTCCAATACATGAAACAGAGGTTGAGCCACATCCAATGGAAAACGTCGTTTTTGTTTGGAACAATATTAATCATGATCCTAACAAGTTTGATATTCCTCTagacataaatataaatgatgatTCCACTCTACCAGAAATGCATCGAGGGTTTGATGCTGAGATTGTTGACGACAATGAAAGCATGAATCTCTCGCCGAGTCAAGCTATTGGAAGGAAGGTATTTAAATGTCCACATTGTCCATTCTTCTCCACAACAGCATCCAGATTTCACGTTCATATCGTGGGGCACTTGAACAAGAAGCCATTTGAGTGTTCCCTCTGCAAATATAAATCTAATTGGAGATGGGATATCACCAAACACATAAAGTTGAAATCCGCGAGGGATCCCGAGCATAATGAAGCAAAAGTACTTATGACCGATGAAACAGGAAGGAGAAACTACAGCAAATACAACAAATTCTTAGCAATGCCTGTTTTGAATGAAAATGGCGAAAATGAGTTCCATTACCTGGATCCTAACACTGCAGTCGATAGCACGATGGAAATTGATGAATCATTTAATGATATCTCAGACGTTATGAATGTACAATTTGAAATGCAACCGCTTAACTTACAGACACAACACATTGAAGATAATTACAACTATATTGATAATAGAAGTCTTAACGAGATGAAGAAGCCAAAGAAGACGCTATGgaaatgtaaaaaatgtaattacaaaGATCCCTCAAAAGAAGCATTATTAGAGCATGTTCGTGAACACTCCAGATCGGATGGCGTCCATGAAGAGCAGAACAAACCACCTGTCAAGAAACCTGAAAACAATACCCCCGACCCAGCAGATCTGGCGTACCGTTGTGGGCATTGCAATCAGCTATCTAATTGGAAACATGTCATCCAGCGCCATTGCCGATTAAAACACGATGGAGTTATCAAAGTGATTACTACAGTTAAACCAAAGCCTGATCCACCGATGAACATCAATGAGATCAACATTGATACTTGCAACAAGTGTCCGTACAGAACGAGTGATAAAAAGCTACTGATCGCTCATTTACAACAGCATCAGCCTTCGCCGAATTCTATTTTCAAGTGCTACTTCTGTCCGTTCTTCGTAAAGGATGAGCCAGAATTAATTCAACATCTGCTTCTGCACGGTATCACTGACCCAGAAGATTACATCGCAAAAGCAATGGGAACTAAATCCCCAGGACCTGAACCACAAGCTCCTGCTACTACGTCATTAAACTCCACCAAACGCCACAAGTGCACAGAATGTCCGTACGAAACTAATAGTAAGTCACAATTCATGTACCACGAGCAATTTCATCGACTTCCGGCGGATACGCCATACAAATGTCCAGAATGCAACTACAGCGTTTCTAAGAGACACCTGCTGCACCAGCATCTGCGAGTCCACGGCATCGCAACCAAAAGAAATGAAACCGAGGCCGAATTAGAAGCATCAACCTCAAGCCAAAACAAGATGGATAAAACGGACTCCCATATTAATCTTGAAGAAATACCATTTGTCTGGGTTTCGGCCAAGAATGAGTTTCATAAAATGTACAAATGTCGATACTGTTCATACGTTAATgctataaaatgtaaaattccAAATCATGAAAAAATTCATTGCATCGTATTCGAAAACAATGATACAAGTTTTTACAAGTGTTTGGAATGCAAATTTACGTGTGATAACCCCGGCAGACTCGCAGAGCATTCCAAAAATCATGCAGAAATATATGGTCGCATTTATTGTCCCGTTGAACATGACGTGCCCGATGAAGAACAAATCacaaaattgagaaaagttaTAGAAATTGAAAAATTAGCAAATCCCGAAAGCACCGCCACGCCAAAAGATGAAGGCACAACTCCAGAAAATAGAGaaatcaaattattatatttttgtcaaaAGTGTCCAGCAAGATTTTTTGATGACGTGGAACTTGAGGCTCATGAAAAATGTCATCAATCAAATCATGGTTTAACGTTGCCCAACAAATGTAAAAGTTGTGACTTTTCGGTCACCGAGGATTTAGAATTAGCGGCACATTTTGTTGTGCACACAGATACAtatcacacaaaaacaaagatGCTTAAATTTATTCACAACTCACATCGCTTACACAGGCCGCCCGTGCTCGAGCTGGTTCACTGGCCAACGACTTCAGAGATTACGTGGGTAGCCACTGGGCCAAGCAAAGCTGAAAATATTGAAAGCCCTATGAAAAAATCGAATGATTCAAAACACGTGCCAAAACAATATAGTTGCAGACAATGTCCAGCAAAGTTTTTCAAAAGTTCTGCGCTTACCTACCACATGGGGCTGCATGGGGGTGAAGGCGAGCACAAGTGCAAGAAGTGCAACTACGCCGTAAAGAACATTGGAAATCTAGCCAAACATGAATTACTACACGATAGTGACAACAAGGGCACAGGTTGCGACTATGAATCCGGTGAAGATATggattataaaaatattccatTGTCGGGTACAGACTTGTTCCAGAGGAAGACTGAAGCTCAGAAAAGAGTGTTAACTGATAAAGATAAGTTAGTTAAACCGAACGATCATTTTCCGCCTGTCCTACAAGCTGATCCCCAGTTCGGTTATCTTATGCATGGTAATCCTGAATTCATATATCCCACCTACTTGAAAAATGGTCGCCAAAAAGAAAAACGTTACAAATGCCACAAGTGTCCGTCAGCGTTTGAGAAAAGAGAACAGTATAAGATTCATTTATCATTGCACGGCTCCAAGCAAAGATATAAATGTGAGTTATGTGATTATTCAGTGAAATATTACGCCAATTACGTTCAACATATGCGAAAACATCAAATGAACGATGAGGCTCAAGCTGAAAGGAAGAAAGGTAACGATTTTACAGAATCAGAACATCAAGAAGACGTCAAGCAAGACGACAGCAGTGATAACATTAAACTTGCAATTAAAACTATGCCAAAAGGAGCTGCTAAGAGCGACTTTCAACAATTCTCAATTAGCGACCAACAAACGCTCAGACTGCTGCAGAGGAGACGGTCAATGAATAATTCTGGAAATCACAACACTTCCGAAACTTCGCCGATCAAAGAGCGCAAAATGCACATGTGTCTATTATGCCCCTACACTAATCAACGTCAAGATTCTTTAAGCAATCATTACAGGAGGCACGGCGACACAGATATCCTGAACGGAGGCAGTCATAAATGTTCTCATTGCGACCTAGTAGTTGTCCAGTCGCATTTCCTCCGGGAGCATCTCAAGACACACTTCAACTACCACAAAACTCTTACTCCTGAATGTTTTGTGGCTAACGAAGCTGTTAGTTTTACTATTACCAAGTTGGAAGAAGAGGGTGAATCAgttgatctcaaattagacatGCAGAGCAAGAGTTCTACATGTAATGATGAAAAGATATTTGTGAAAATTAAAACTGGAGAGCTATTGGTAGAATAA
Protein Sequence: MLQQMSSPPRAQVGEVATIVRHLEGRVCGDVSSEASSDAAEDFELPQCKIRRNYNCTKCTFYTQNPRAYLVHTRDAHFVRLKIYDCPHCVYASRHHQKLIRHVKMVHGGTKQASTTSAKVEELSPPPNDNMEPAERIEDMLEEVEDCEEMMMEVDEDSMDRLDDVDGDGDQSVDFESPYRRARLSKAKGKFFSCDKCNYVTHIRARFTKHVKYHSMPMIKCTMCDFRTPYKWNLDRHMKNHGGSGSFNCSMCNFTADIKQSLTVHEMNHHTPAAGQSLPSRRRNRVGASDTVIAEYDAASALLPKEEEGSGDSRSSHSVSDMGLQYAERELVSCKSDSNDGTASDAITNRKETSQDGYNLSPTHSADEKLQKQSRKVPRPIPQLIPLNSSTPNQKQTGEPPQKKFKESLPDSDDVSAENTLLPATQSMKETAGRKKNESFFDRLKERLLTETGEEGSLICKICGFESKCLSEHSVHEKNCSPQMNRINANTSLKSLSSTRCQNCRHRCKSSADLYIHMQTCVKGDSADNESSIKIDNSNDEVIPIHETEVEPHPMENVVFVWNNINHDPNKFDIPLDININDDSTLPEMHRGFDAEIVDDNESMNLSPSQAIGRKVFKCPHCPFFSTTASRFHVHIVGHLNKKPFECSLCKYKSNWRWDITKHIKLKSARDPEHNEAKVLMTDETGRRNYSKYNKFLAMPVLNENGENEFHYLDPNTAVDSTMEIDESFNDISDVMNVQFEMQPLNLQTQHIEDNYNYIDNRSLNEMKKPKKTLWKCKKCNYKDPSKEALLEHVREHSRSDGVHEEQNKPPVKKPENNTPDPADLAYRCGHCNQLSNWKHVIQRHCRLKHDGVIKVITTVKPKPDPPMNINEINIDTCNKCPYRTSDKKLLIAHLQQHQPSPNSIFKCYFCPFFVKDEPELIQHLLLHGITDPEDYIAKAMGTKSPGPEPQAPATTSLNSTKRHKCTECPYETNSKSQFMYHEQFHRLPADTPYKCPECNYSVSKRHLLHQHLRVHGIATKRNETEAELEASTSSQNKMDKTDSHINLEEIPFVWVSAKNEFHKMYKCRYCSYVNAIKCKIPNHEKIHCIVFENNDTSFYKCLECKFTCDNPGRLAEHSKNHAEIYGRIYCPVEHDVPDEEQITKLRKVIEIEKLANPESTATPKDEGTTPENREIKLLYFCQKCPARFFDDVELEAHEKCHQSNHGLTLPNKCKSCDFSVTEDLELAAHFVVHTDTYHTKTKMLKFIHNSHRLHRPPVLELVHWPTTSEITWVATGPSKAENIESPMKKSNDSKHVPKQYSCRQCPAKFFKSSALTYHMGLHGGEGEHKCKKCNYAVKNIGNLAKHELLHDSDNKGTGCDYESGEDMDYKNIPLSGTDLFQRKTEAQKRVLTDKDKLVKPNDHFPPVLQADPQFGYLMHGNPEFIYPTYLKNGRQKEKRYKCHKCPSAFEKREQYKIHLSLHGSKQRYKCELCDYSVKYYANYVQHMRKHQMNDEAQAERKKGNDFTESEHQEDVKQDDSSDNIKLAIKTMPKGAAKSDFQQFSISDQQTLRLLQRRRSMNNSGNHNTSETSPIKERKMHMCLLCPYTNQRQDSLSNHYRRHGDTDILNGGSHKCSHCDLVVVQSHFLREHLKTHFNYHKTLTPECFVANEAVSFTITKLEEEGESVDLKLDMQSKSSTCNDEKIFVKIKTGELLVE*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01231174;
90% Identity: iTF_00953155;
80% Identity: -