Basic Information

Insect: Lacanobia wlatinum
Gene Symbol: IKZF1
Assembly: GCA_947578705.1
Location: OX388028.1:18973426-18981194[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 3.2 2.8e+02 3.0 0.9 1 23 54 77 54 77 0.94

2 20 0.087 7.6 7.9 4.1 1 23 84 107 84 107 0.97

3 20 5.1 4.4e+02 2.3 4.0 1 23 192 214 192 214 0.96

4 20 0.0017 0.15 13.2 1.0 2 23 220 241 219 241 0.97

5 20 2.1 1.8e+02 3.5 1.4 1 23 247 269 247 270 0.94

6 20 0.21 18 6.7 3.4 2 22 504 524 503 524 0.95

7 20 0.087 7.6 7.9 2.6 1 23 621 643 621 643 0.95

8 20 0.6 52 5.2 0.3 2 23 780 801 779 801 0.96

9 20 0.0011 0.1 13.8 0.5 2 23 881 902 880 902 0.96

10 20 0.13 12 7.3 0.3 1 23 910 932 910 932 0.97

11 20 5 4.4e+02 2.3 2.6 1 23 968 990 968 990 0.93

12 20 0.00024 0.021 15.9 4.0 1 23 998 1020 998 1020 0.99

13 20 0.24 21 6.5 1.8 1 23 1104 1126 1104 1126 0.97

14 20 1.1 96 4.4 1.5 1 20 1183 1202 1183 1205 0.92

15 20 0.037 3.3 9.0 2.5 1 23 1304 1326 1304 1326 0.95

16 20 0.0055 0.48 11.6 1.1 1 23 1332 1354 1332 1354 0.96

17 20 0.0068 0.59 11.4 2.6 1 23 1444 1466 1444 1466 0.97

18 20 0.00017 0.015 16.4 1.4 1 23 1472 1494 1472 1494 0.99

19 20 0.84 73 4.8 2.7 1 23 1584 1606 1584 1606 0.96

20 20 0.0099 0.86 10.8 5.6 1 23 1617 1639 1617 1639 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	3.2	2.8e+02	3.0	0.9	1	23	54	77	54	77	0.94
2	20	0.087	7.6	7.9	4.1	1	23	84	107	84	107	0.97
3	20	5.1	4.4e+02	2.3	4.0	1	23	192	214	192	214	0.96
4	20	0.0017	0.15	13.2	1.0	2	23	220	241	219	241	0.97
5	20	2.1	1.8e+02	3.5	1.4	1	23	247	269	247	270	0.94
6	20	0.21	18	6.7	3.4	2	22	504	524	503	524	0.95
7	20	0.087	7.6	7.9	2.6	1	23	621	643	621	643	0.95
8	20	0.6	52	5.2	0.3	2	23	780	801	779	801	0.96
9	20	0.0011	0.1	13.8	0.5	2	23	881	902	880	902	0.96
10	20	0.13	12	7.3	0.3	1	23	910	932	910	932	0.97
11	20	5	4.4e+02	2.3	2.6	1	23	968	990	968	990	0.93
12	20	0.00024	0.021	15.9	4.0	1	23	998	1020	998	1020	0.99
13	20	0.24	21	6.5	1.8	1	23	1104	1126	1104	1126	0.97
14	20	1.1	96	4.4	1.5	1	20	1183	1202	1183	1205	0.92
15	20	0.037	3.3	9.0	2.5	1	23	1304	1326	1304	1326	0.95
16	20	0.0055	0.48	11.6	1.1	1	23	1332	1354	1332	1354	0.96
17	20	0.0068	0.59	11.4	2.6	1	23	1444	1466	1444	1466	0.97
18	20	0.00017	0.015	16.4	1.4	1	23	1472	1494	1472	1494	0.99
19	20	0.84	73	4.8	2.7	1	23	1584	1606	1584	1606	0.96
20	20	0.0099	0.86	10.8	5.6	1	23	1617	1639	1617	1639	0.98

Sequence Information

Coding Sequence: ATGCTACAGCAGATGTCCTCGCCGCCGCGCGCACAAGTCGGCGAGGTCGCGACTATCGTGCGCCACCTTGAAGGCCGCGTCTGCGGCGACGTGTCTTCGGAGGCTTCCTCGGACGCCGCCGAAGATTTCGAATTACCACAGTGCAAGATAAGGAGGAATTATAATTGCACCAAGTGCACGTTCTATACGCAGAACCCGCGCGCTTATCTCGTCCACACGCGTGACGCTCACTTCGTCAGACTCAAGATTTACGATTGTCCACACTGTGTTTACGCTTCGAGACATCATCAAAAACTTATAAGACACGTCAAAATGGTTCACGGAGGAACAAAACAAACTTCTACCACTTCTTCAAAAGTGGAAGAGCTATCACCGCCCCCCAACGATAACATAGAGCCGGTAGAGCGCATTGAAGACATGCTTGAGGAAGTCGAGGACTGCGAGGAGATGATGATGGAAGTAGATGAGGACTCCATGGACCAACCTGATGATGTCGACGGCGACGGCGACCAAAGTGCAGACTTCGGATCGCCCTATCGGAGGGCACGTCTGTCAAAAGCTAAGGGCAAATTCTTCTCATGCGATAAGTGTAACTATGTCACCCACATAAGAGCTAGATTCACAAAACATGTCAAGTATCATTCGATGCCTATGATCAAGTGTACAATGTGTGATTTTCGAACACCATACAAGTGGAATTTGGACCGTCACATGAAGAACCACGGTGGAAGTGGAAGTTTCAATTGTTCGATGTGCAACTTCACGGCAGACATCAAGCAGAGTCTGACGGTGCACGAAATGAATCATCACACACCGGCAGCGGGCCAATCGCTGCCGAGCCGCCGCCGCAACCGGGTGGGCGCCAGCGACACGGTTATCGCGGAGTACGACGCGGCGAGCGCGTTGCTCCCCAAGGAGGAAGAAGGGAGCGGCGACTCGCGGTCCTCACACTCGGTCTCGGACATGGGTCTCCAATACGCAGAGAGAGAACTAGTCAGTTGCAAAAGTGACTCCAACGACGGTACAGCATCTGACGCGATCCCCAACCGAAAGGAAACTTCACAAGATGGATACAACCTTTCACCAACCCACAGCGCAGATGAGAAGCTCCAAAAACAAAGTAGAAAGATTCCCAGGCCAATACCACAACTCATACCCCTAAATTCATCGACACCTAACCAAAAGCAAACCTGCTCTGGTGAACCACCACATAAAAAGTTTAAGGATTCTTTACCCGGCAGCGATGATGTATCTGCTGAAAATACTCTCTTACCAGCAAACCCATCGATAAAAGAGACTGCTGCTGCTGGTCGAAAGAAAAATGAATCATTTTTCGACAGATTAAAAGAAAGACTGCTTACAGAAACAGGCGAAGAAGGTTCACTAATATGTAAGATCTGTGGATTTGAAAGTAAATGCTTATCAGAACATTCTGTGCACGAGAAAAATTGTTCTCCACAAACGAATCGGATCAATGCAAACACGTCGCTGAAAAGTTTAAGTTCCACTCGATGCCAGAATTGTAGACACAGGTGTAAGTCTAGTGCAGACTTGTACATCCACATGCAAACTTGCGTTAAAAGCGACTCCGTCGACAATGAAAGCTCTATGAAAATTGATAATAGTAACGATGAAGTTATTCCAATCCATGAAACAGAGACTGAGCCGCATCCAATGGAAAACGTCGTTTTCGTTTGGAACAATATTAATCATGACCCTAACAAGTTTGATATACCCCTAGACATAAATATAAATGATGATTCCACTCTACCAGAAATGCATCGAGGTTTTGATGCTGAGATTGTTGACGACAATGAAAGCATGAATCTATCGCCGAGTCAAGCCATTGGAAGGAAGGTATTTAAATGCCCACATTGTCCATTCTTCTCCACAACAGCATCTAGATTTCACGTTCATATCGTGGGTCACTTAAACAAGAAACCGTTTGAGTGTTCCCTCTGCAAATATAAATCAAATTGGAGATGGGATATTACCAAACACATTAAATTGAAATCCGCGAGGGATCCCGAGCATAATGAAGCAAAAGTACTTATGACCGATGAAACAGGAAGAAGAAACTATAGCAAATACAACAAATTCTTAGCAATGCCTGTTTTGAATGAAAATGGCGAAAATGAGTTCCATTACCTAGATCCAAACACTGCAGTCGATAGCACGATGGAAATGGATGAATCATTTAATGATATCTCAGACGTTATGAATGCACAATTTGAAATGCAACCGCTTAACTTACAGACACAACACAGTGAAGATAATTACAACTATATTGATAATAGAGGTCTCAACGAGATGAAGAAGCCCAAGAAGACGCTATGGAAATGTAAAAAATGTAATTACAAAGATCCATCAAAAGAAGCACTGCTAGAGCATGTTCGTGAACACTCCAGAGTAGAAGGCGTCCATGAAGAGCCAAACAAACCACCTATTAAGAAACCTGAAAACAATACTCCTGACCCAGCAGATCTGGCGTACCGTTGTGGGCACTGCAATCAGCTGTCTAATTGGAAACATGTCATCCAGCGCCATTGCCGATTAAAACACGATGGAGTGATCAAAGTGATAACTACAGTTAAACCAAAACCTGATCCACCGATGAACATCAATGAGATCAACATTGATACTTGCAACAAGTGTCCGTACAGAACGAGTGACAAAAAGCTACTGATCGCCCATTTACAACAGCATCAGCCTTCGCCGAATTCTATTTTCAAGTGCTACTTCTGTCCGTTCTTCGTAAAGGATGAGCCAGAATTAATTCAACATCTACTCCTGCACGGTATCACCGACCCAGAAGATTACATCGCAAAAGCAATGGGAACTAAATCCCCAGGACCAGAACCGCAAGCTCCTGCTACTACGTCATTAAACTCCACGAAGCGCCACAAATGCATAGAATGTCCATACGAAACAAACAGTAAGTCACAATTCATGTACCACGAACAATTTCATCGACTTCCGGCGGATACGCCGTACAAATGTCCAGAATGCAACTACAGCGTTTCTAAGAGACACTTGCTGCACCAGCATCTGCGAGTCCACGGCATCGCAACCAAAAGAACAGAAACCGAGGCCGAATTAGAAGCCTCAACATCCACCCAAAACAAGATGGATAAAACGGAATCCCATATTAATCTTGATGAAATACCATTTGTCTGGGTTTCGGCCAAGAATGAGTTTCATAAAATGTACAAGTGCCGATACTGTTCGTACGTTAATGCTATAAAATGTAAAATACCAAATCATGAAAAAATTCATTGCATCGTATTCGAAAACAATGATACAACTATTTATAAGTGTTTGGAATGCAAATTCACGTGTGATAACCCCGGCAGACTAGCGGAGCATTCCAAAAATCATGCAGAAATATATGGTCGCATTTATTGTCCCGTTGAACATGATGTGCCCGATGACGAACAAATCACAAAATTGAGAAAAGTTATAGAAATTGAAAAATTAGCAAATCCCGAAAGTACCGCAATCCCAAAAGATGAAAGCACTACGCAAGATAGAGAAATAAAATTACTATATTTTTGTCAAAAGTGTCCAGCAAGATTTTTTGATGACGTCGAACTTGAGGCTCATGAAAAATGTCATCAATCAAATCATGGTTTAACATTGCCCAACAAATGTAAAAGTTGTGACTTTTCGGTCACCGAAGATTTAGAATTAGCGGCACATTTTGTTGTGCACACAGATACATATCACACAAAAACAAAGATGCTTAAATTTATTCACAACTCACATCGGTTACACAGGCCACCCGTGCTCGAGTTGGTTCACTGGCCAACGACTTCAGAGATTACTTGGGTAGCCACTGGGCCGAGCAAAGCTGAAAATATTGAAAGCCCTGTAAAAAAAACGCATGATTCAAAACACGTGCCAAAACAATATTGTTGCAGACAATGCCCAGCGAAGTTTTTCAAAAGTTCCGCGCTTACCTACCACATGGGGCTACATGGGGGTGAAGGCGAGCACAAGTGCAAGAAGTGCAACTACGCCGTGAAGAACATCGGAAATCTAGCCAAACATGAATTACTTCACGATAATGAAAACAAGGGTACAAGTTGCGACTATGAATCCGGTGACGATATGGATTATAAAAATATTCCATTGTCAGGCACAGATTTGTTCCAGAGGAAGACTGAGGCTCAGAAAAGAGTTTTATCTGATAAAGATAAGTTAGTTAAACCGAACGATCATTTCCCGCCTGTCCTACAAGCTGATCCTCAGTTCGGATATCTAATGCATGGTAATCCGGAATTCATATATCCCACCTACTTGAAAAATGGTCGCCAAAAAGAAAAGCGATACAAATGCCACAAGTGTCCGTCAGCATTTGAGAAACGAGAACAATATAAGATTCATTTATCATTGCACGGCTCCAAGCAAAGATATAAATGTGAACTGTGTGATTATTCAGTGAAATATTACGCCAATTACGTTCAACATATGCGAAAACACCAAATGAACGATGAAGCTCAAGCTGAAAGGAAGAAAGGTAGTGATTTTACAGAATCAGAACATCAAGAAGACGTAAAGCAAGACGACAGCAGTGATAACATTAAACTTGCAATAAAAACTATGCCAAAAGGAGCTGCAAAGAGCGACTTTCAACAATTCTCAATTAGCGACCAACAAACGCTCAGACTGCTGCAGAGGAGACGGTCAATGAATAATTCTGGAAACCACATCACTTCTGAAACTTCGCCAGTCAAAGAGCGCAAAATGCACATGTGTCTATTATGTCCCTACACTAATCAACGTCAAGATTCTTTAAGTAATCATTACAGGAGGCATGGTGACACCGATATCCTAAACGGTGGCAGTCATAAATGTTCTCATTGCGACCTAGTGGTTGTTCAGTCGCATTTCCTACGGGAACATCTCAAGACACACTTCAACTACCACAAAACTCTCATACCTGAATGTTTTGTGGCTAATGAAGCTGTTAGTTTTACTATAACCAAGTTGGATGAAGAGGGTGAATCAGTTGATCTCAAATTAAATATGCAGAACAAGAGTAATGCATGTAATGATGAAAAGATATTTGTGAAAATTAAAACTGGAGAGCTATTGGTAGAATAA
Protein Sequence: MLQQMSSPPRAQVGEVATIVRHLEGRVCGDVSSEASSDAAEDFELPQCKIRRNYNCTKCTFYTQNPRAYLVHTRDAHFVRLKIYDCPHCVYASRHHQKLIRHVKMVHGGTKQTSTTSSKVEELSPPPNDNIEPVERIEDMLEEVEDCEEMMMEVDEDSMDQPDDVDGDGDQSADFGSPYRRARLSKAKGKFFSCDKCNYVTHIRARFTKHVKYHSMPMIKCTMCDFRTPYKWNLDRHMKNHGGSGSFNCSMCNFTADIKQSLTVHEMNHHTPAAGQSLPSRRRNRVGASDTVIAEYDAASALLPKEEEGSGDSRSSHSVSDMGLQYAERELVSCKSDSNDGTASDAIPNRKETSQDGYNLSPTHSADEKLQKQSRKIPRPIPQLIPLNSSTPNQKQTCSGEPPHKKFKDSLPGSDDVSAENTLLPANPSIKETAAAGRKKNESFFDRLKERLLTETGEEGSLICKICGFESKCLSEHSVHEKNCSPQTNRINANTSLKSLSSTRCQNCRHRCKSSADLYIHMQTCVKSDSVDNESSMKIDNSNDEVIPIHETETEPHPMENVVFVWNNINHDPNKFDIPLDININDDSTLPEMHRGFDAEIVDDNESMNLSPSQAIGRKVFKCPHCPFFSTTASRFHVHIVGHLNKKPFECSLCKYKSNWRWDITKHIKLKSARDPEHNEAKVLMTDETGRRNYSKYNKFLAMPVLNENGENEFHYLDPNTAVDSTMEMDESFNDISDVMNAQFEMQPLNLQTQHSEDNYNYIDNRGLNEMKKPKKTLWKCKKCNYKDPSKEALLEHVREHSRVEGVHEEPNKPPIKKPENNTPDPADLAYRCGHCNQLSNWKHVIQRHCRLKHDGVIKVITTVKPKPDPPMNINEINIDTCNKCPYRTSDKKLLIAHLQQHQPSPNSIFKCYFCPFFVKDEPELIQHLLLHGITDPEDYIAKAMGTKSPGPEPQAPATTSLNSTKRHKCIECPYETNSKSQFMYHEQFHRLPADTPYKCPECNYSVSKRHLLHQHLRVHGIATKRTETEAELEASTSTQNKMDKTESHINLDEIPFVWVSAKNEFHKMYKCRYCSYVNAIKCKIPNHEKIHCIVFENNDTTIYKCLECKFTCDNPGRLAEHSKNHAEIYGRIYCPVEHDVPDDEQITKLRKVIEIEKLANPESTAIPKDESTTQDREIKLLYFCQKCPARFFDDVELEAHEKCHQSNHGLTLPNKCKSCDFSVTEDLELAAHFVVHTDTYHTKTKMLKFIHNSHRLHRPPVLELVHWPTTSEITWVATGPSKAENIESPVKKTHDSKHVPKQYCCRQCPAKFFKSSALTYHMGLHGGEGEHKCKKCNYAVKNIGNLAKHELLHDNENKGTSCDYESGDDMDYKNIPLSGTDLFQRKTEAQKRVLSDKDKLVKPNDHFPPVLQADPQFGYLMHGNPEFIYPTYLKNGRQKEKRYKCHKCPSAFEKREQYKIHLSLHGSKQRYKCELCDYSVKYYANYVQHMRKHQMNDEAQAERKKGSDFTESEHQEDVKQDDSSDNIKLAIKTMPKGAAKSDFQQFSISDQQTLRLLQRRRSMNNSGNHITSETSPVKERKMHMCLLCPYTNQRQDSLSNHYRRHGDTDILNGGSHKCSHCDLVVVQSHFLREHLKTHFNYHKTLIPECFVANEAVSFTITKLDEEGESVDLKLNMQNKSNACNDEKIFVKIKTGELLVE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01231174;
90% Identity: iTF_00953155;
80% Identity: -