Idim004444.1
Basic Information
- Insect
- Idaea dimidiata
- Gene Symbol
- gprs
- Assembly
- GCA_949358125.1
- Location
- OX442328.1:9837388-9841542[-]
Transcription Factor Domain
- TF Family
- BTB
- Domain
- zf-C2H2|ZBTB
- PFAM
- PF00651
- TF Group
- Zinc-Coordinating Group
- Description
- The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 1.3e-09 4.4e-07 30.8 0.0 9 45 36 73 28 91 0.84 2 2 6.8e-06 0.0023 18.8 0.0 43 81 119 157 107 162 0.71
Sequence Information
- Coding Sequence
- ATGCGAAGCGGGGCGCTAGCTGCAATGGAGGCGGAACCCGACCTCAGCACTTTCGAGAACAAGTCGGGTCTGGCCGAAGACATGAAGTTCTTGGCCTCGATGCCGGAGCTGTGTGATGTCACATTCCTAGTTGGAGATACTAGGGAACCAGTGTGTGCTGTGAAAGCGGTTCTCGCTGCAAGAAGCAGGGTTTTCCAAAAAATGTTGTATCAAGCACCAAGTCCCCAAAGAAAGAAGGAGCCAGCACCCAGAGAGAATAAACTAAGACTATTTTTGAAGAGATCTTCAGAACCCTTACTGAATCTGCAAAACGCCGCTCAACAGAGATCGACTTTCGCCCAGCAATTGGCTCCAATACAAGagCCGTCGTCCCAACAACACCAAACCCTTATCATTGAAGAATTCGAACCCGATGTGTTCCGCCAGCTGATTGAGTACATTCACACTGGATGCGTGACCTTGCAGCCTAGGACTTTGCTTGacaatcAAGGCGTCCGTCCGTCATACGTCCCTTATGGGCCGGCTTTggcatag
- Protein Sequence
- MRSGALAAMEAEPDLSTFENKSGLAEDMKFLASMPELCDVTFLVGDTREPVCAVKAVLAARSRVFQKMLYQAPSPQRKKEPAPRENKLRLFLKRSSEPLLNLQNAAQQRSTFAQQLAPIQEPSSQQHQTLIIEEFEPDVFRQLIEYIHTGCVTLQPRTLLDNQGVRPSYVPYGPALA
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00712097; iTF_01533237; iTF_01062042; iTF_00281548; iTF_01192883; iTF_00445377; iTF_00419884; iTF_01426067; iTF_00405172; iTF_00637858; iTF_00776149; iTF_01182021; iTF_00027942; iTF_00041962; iTF_00781162; iTF_00784558; iTF_00994511; iTF_00674453; iTF_00776825; iTF_00009244; iTF_00952860; iTF_00778878; iTF_00446392; iTF_00125273; iTF_00159999; iTF_00636672; iTF_01076704;
- 90% Identity
- iTF_00013245;
- 80% Identity
- iTF_00041962;