Basic Information

Gene Symbol
-
Assembly
GCA_905147285.1
Location
LR990155.1:3358971-3361516[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 0.0012 0.13 13.9 1.0 1 23 5 27 5 27 0.91
2 14 0.022 2.2 10.0 0.2 1 23 100 122 100 122 0.97
3 14 0.0011 0.12 14.0 0.1 1 23 126 148 126 148 0.95
4 14 0.0046 0.47 12.1 0.3 1 23 153 176 153 176 0.95
5 14 0.0006 0.061 14.9 2.5 1 23 182 205 182 205 0.96
6 14 0.044 4.5 9.0 0.4 1 11 212 222 212 226 0.88
7 14 0.01 1.1 11.0 0.6 1 23 333 356 333 356 0.97
8 14 0.66 67 5.3 0.1 1 23 427 449 427 449 0.91
9 14 0.0005 0.051 15.2 0.2 1 23 453 475 453 475 0.98
10 14 0.00024 0.025 16.1 0.3 1 23 480 503 480 503 0.96
11 14 0.0056 0.58 11.8 0.4 2 23 510 532 510 532 0.93
12 14 0.046 4.7 9.0 6.4 1 23 539 562 539 562 0.96
13 14 1.3e-05 0.0013 20.2 2.7 2 23 569 590 568 590 0.96
14 14 0.00012 0.012 17.1 1.7 1 23 596 618 596 618 0.98

Sequence Information

Coding Sequence
ATGAAGAATCTCTACATCTGTTTCTTCTGCGATCAACAATTTTCTGATCCATCAAAATTAAGAGTCCATAATTACGAACACGGTACTTTAACAACTACTCAACTAAAACATGCGCTATCGAAGCTTAGGAAGTACGAATTAGTCAAAGTAGACGTAACCGATGTCAGTTGCAAGTTCTGTGAAGATCTAATCACTGATTTTCAAACCCTAAAATGGCATTTGCTTGATAAACATAAAAAGCACTTAGATCCAAAATCCGCCGACGGAGTGCTACCTTTCAAAGTGACGTTAGACGAGTTTCCATGCGTGCTGTGTGTTGAAAAGTACGCCGAATTTAAGTCGTTAAATCAACACATGAATGTGCACttccagaatttcatttgcgaGTTGTGTGGTACTGGTTTTGTTACTCCAGAACGATTAAGAACTCATGCGTTTTCGCACGAAACAGGCTCCTTCCCTTGCGAAAGTTGTGACAAAGTATTTCGATCAACCAACGCGAAGAATGAGCACTATGCCACTGTTCATATGAAAGTCAAACGCCATAGATGTCCGCAATGCCCAGAAACATTCCGAAACTACTTCCAGAGAAACAAACACATATCTTCAATACACGGTCTAAAACTAAAAGAGTTCAAATGCACTATGTGTCCGAAAGTCTTCACTTTGAGTGGATCCGACTCCATAGTGGACTCCAAGCGAAGAATAGTGCCGTTATTCCAAGTGTCATACGACCGAAGCCTCTGTAAACCTCTCGGCACGATTTTCAACTTCAGCGCACTTAAAAAGACTTACAAAGCGATCTCTAGAGAATTAACCCCGTCCAGAAGTCCTTCTCCTGTTTATATGGCAAGATCTCCTTCACCTTTTGTTGAGAAACCAGAATCTATCGAACCCGAGCAACCTAAAGCTAAGAAAAATCCTGACATAAGGCAGAATGCTCTGGCAGTGTTCGAATTCTCAACTGTATATCCCTTCGTATACggaaataataaattcaaatgttTTGTCTGCTCCCAACCGTTTCTGGACCTCAATTTGCTAAAGGAGCATATGCGCGAAACCCATGCATTTGCTCCTTTGAAAAGACTAGTAAATAATAGAAGAGAAAACGTTTTAAAAGTAGATGTGAGTGAGATAACTTGCAAAATATGTTCAGCAAAACCCCTAGATCTGATAGACTTGAAACGTCATCTAAAAGAACATCACGACAAACCGATAAATTTAGATATTCAGGACAATTTGATACCTTTCAAATTAGAATTAGTAGATGGATCGTACAGTTGCGTGATTTGTAAGCagaattttataaaagtaagaaTTTTGGTGATACATATGAGCGCTCATTTCAATAACTATAGCTGTGAAGTTTGTGGCTCTGGCTTCATGACCTTACGACTTCTGAAAAAGCATTTGGAGGTTCATGAAACAGGGAACTTTCCATGTGATCGTTGTAATAAAGTTTTTAGCACTCCTTACAAAAAGGCTTTACATATTCGAGGTGTCCATCTTAAGCAGTGTCCTAGAAGATGTCCTATGTGTCCGGAGAGGTTCAACTCAAATTATAAGAGGACTATTCATTTGCAAGACGTTCACAATCAGGCGACTAGGGTGCATAAGTGTGAGACCTGCGGTCGTGGGTTCAACTTGAAGTACCATTTGATCTGTCACACTCGGTCTGTACACCTGCAGGAGAGGAATCAGCAGTGTGAGATCTGTCAACAGAGATTTTGCAACAAGGAGTCTTTGAAACGGCATATGGTGATACACACGGGCGAAAAAAACCATAAATGTGATGTGTGCGGTATGGCGTTCTTGAGGAGAAAGAATCTAAAGGATCATTTGAGATTGCATAATATTGGatga
Protein Sequence
MKNLYICFFCDQQFSDPSKLRVHNYEHGTLTTTQLKHALSKLRKYELVKVDVTDVSCKFCEDLITDFQTLKWHLLDKHKKHLDPKSADGVLPFKVTLDEFPCVLCVEKYAEFKSLNQHMNVHFQNFICELCGTGFVTPERLRTHAFSHETGSFPCESCDKVFRSTNAKNEHYATVHMKVKRHRCPQCPETFRNYFQRNKHISSIHGLKLKEFKCTMCPKVFTLSGSDSIVDSKRRIVPLFQVSYDRSLCKPLGTIFNFSALKKTYKAISRELTPSRSPSPVYMARSPSPFVEKPESIEPEQPKAKKNPDIRQNALAVFEFSTVYPFVYGNNKFKCFVCSQPFLDLNLLKEHMRETHAFAPLKRLVNNRRENVLKVDVSEITCKICSAKPLDLIDLKRHLKEHHDKPINLDIQDNLIPFKLELVDGSYSCVICKQNFIKVRILVIHMSAHFNNYSCEVCGSGFMTLRLLKKHLEVHETGNFPCDRCNKVFSTPYKKALHIRGVHLKQCPRRCPMCPERFNSNYKRTIHLQDVHNQATRVHKCETCGRGFNLKYHLICHTRSVHLQERNQQCEICQQRFCNKESLKRHMVIHTGEKNHKCDVCGMAFLRRKNLKDHLRLHNIG*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2