Hlab002061.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Habropoda laboriosa
Gene Symbol
-
Assembly
GCA_001263275.1
Location
NW:1532863-1536141[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.0073 0.41 10.4 0.2 3 23 507 529 506 529 0.94
2 10 0.0054 0.3 10.8 0.9 1 23 535 559 535 559 0.98
3 10 0.0003 0.017 14.7 0.3 1 23 565 589 565 589 0.96
4 10 0.001 0.057 13.1 0.3 3 23 597 619 596 619 0.91
5 10 0.0033 0.19 11.4 3.9 1 21 626 648 626 650 0.95
6 10 6e-05 0.0034 16.9 0.4 2 23 658 681 657 681 0.95
7 10 2.4e-05 0.0014 18.2 1.8 1 23 687 711 687 711 0.93
8 10 3.6e-05 0.002 17.6 0.6 1 23 717 741 717 741 0.95
9 10 5.8e-05 0.0033 17.0 1.2 1 23 747 769 747 769 0.99
10 10 3.7e-05 0.0021 17.6 1.1 1 23 859 884 859 884 0.96

Sequence Information

Coding Sequence
ATGATCTACAAGGTTTCCTTCGATGGCGGCGTTGTTGCTGTGTGTGGACCCCTACAGAGCTGGCTACGGGGTAGTCAAATGTCTCGTAAAGGAACTCCCTCCGCTTGCAAGTCAAAACAAATCCCGCGAATCTTTCGTAACCGGCGAGGTTTGTGTTCGGTTCGCGGTTGGCCGCACGGCGAGGTCGGCGTTGTGGGTGGATCGGTAGGTTACAGTCAGTCGAGTCTGTTGTCCGCTTCGCCGGATGAGGAGAAAACggaagatacaaataaaaaaggaaaacataaAGCGGAGACAGACGACGAGACTGCACAGTATCACCATAGAGTGTGGATCGAGGGTAATCAAGTGACAAACGGTGTTGTAACTAGCGAGCCGTGTATTGTTGACGGAATCGGTAAAGTCGCCGATGTCGAGACTGTAGCGGACATTGAGAAATGGTTAAAAACACGCACGGAATCCGTGTCGAGCATGGATCTCGACGCGATCAAGTCCGGGGTCGAGGAGGGCGTCGACCGGTACCTGGGCGAGGAACTCCAGCACGCTTTTCTGGAAAAGGACCCTGACGGATTGTCGATCGACATCGATCTGTCAGACAAAAAACTCAATTTAGGTTATGATCCTTTGCTTCAGGAGCTTCAGAATGAGAAGCTGCTGGACGAGAAGGATAGCTTTATACTGCCGGAATTTCAGCTGGATCATTTGGATCCGTTGGCGTTATCTCCGGACGATATGATGGTTGCCGGTGAAATTTTACCGTCGACCAGTGCTCAACCTACTTTAACTGTCTCTAATAGAGATGTCGAAGGATTATGTGCGGAAACTGAACAAGCTTCGTTGTTGAAGAAGGCCATGATTGTTGATGGCCAAGAGTCACAAAACAAGTCCACACAGGTTGTTGTAGACGACTTGCGTGTTATAGATGAAGTGAATAAAGATGTTCAATTACAAAAGGACAATAGCCCATCTGAAAATACTATGAATCTCTATGTGCAGGATCTCAGTTCTGAAAATATAGTAGAAGAGTTGTCAGGAGCAAAGCTGGTTGAAGGTGATTCTGAAAATGTTATAATTGAACAATTGAAAACAAAGGCTAAGGTGAAGTTGGAACCACGTATTATTAAGAAGCGTAAAAAGATACCGGAAAcattagagaaaaaatttgagagtgAGATTAAGATATGTGGAGAGGATGTTGTAGACACTGAGGATGGTGTAATGGCTGTTGTCGCCATATCAACCGACAAGATTTCAAATATGACACAAATTGTTATAAACACTGGTACAGAAGAACAGATTTATCAAGGGAAGACTTCAGAGCTCATAGAAGCTAcaggaaattttccaaaattgccAAAAATAGAAACTTCAACAGTGTGGAATGGAACAATAGAACAGAGTGCAGAAAATCCTAATAACCAACATGAATTGGTGATATCAAATGCTTTAGAGGAATTAGGTATTACAGATGACAACTTACAGCCAATATCTGTCAATGAGCATGGGAAAGTATGGCTCTGTCCACGTGATGATTGCAATAGGCAATTTAGTAAACTTTATGCATTGAAAGGCCATTTATTAGCACACTATGGTGTAAGACCATTTAAGTGTGATTTCGAAGGGTGTGCCTGGGcattttattcagaatttaaGCTCAAACGACACAAAGAAACGCATTTGAAACGTAAAGACTATATTTGCGAGGTACAAGGTTGTAATCGTCGATTTACTacgatttataatttatggAGTCACGCGAAGTTGCATAGTCGCCCGAATAGGATATTGTGTCAAGTGCCAGACTGCCAGGAGAAATTTCAGACAAAGAGAGCTCTAGAACTGCACATGAAGTCTCATGACCAGAGTCATGCTCCGTATGTCTGTAAACACGAAGGTTGCGGAAAGAGATATTATAGTAGTAACGCTTTGACGTCGCATCAAAGATGCCATAGTTATAAGGAAGTAGATGTAAAATGCTCGTGGCCAGGCTGCGGTAAAGTATTCGACAAGCCTTGTAGGCTCAAGGCACACATACGCTCGCATACTGGCTGCAAACCTTACCTTTGTACATTTCAAGGCTGCCAGTGGGCGTTCTCTTCTTCTAGCAAATTGAAGAGACACCAGAAAAAGCACACTAATGAACGGAAGTTCGTGTGCGACGTTCCTTCCTGTGGAAAAGCATTTATGAGATCTGAGCATCTCAAGGAGCATAGATTAACGCATAAGGAAGGAAGATACTTTCAATGTTTTATATGTAACGCGAAGTTTTCTGCAAAAAGTAGTTTGTACGTTCATATAAAGAAGCATCAAGTTAAAGAAGAGGTAGAGGCGAATTTACACGATACTATCAATGGTCATAAACGGAGCAAACTGAAGGAAACGCAATGCTCTAGGGTTAATCCGGTTGTGAAATCAAAAAGAAAGTCAATAGATCTGAATATTAATGCGGCTTGCCTAAACACGTCTACAGTGACGGAGAACTCTGAACACATAAACGATGCAAATATCAGAAATAATAATGAGAATCAAACTAAAGACGATACAGTGCCTCCACAAGATCAATCTAAGACTTTATACCATTGTCCAGTTGAAACCTGCACACGTTCGTATACTACAAAAGCTACGTTAAGAGCACACATGTTAAAAGTACACGGTACACCTGTTGAAGAGTGCGCAGACAAAACATCCAAAAGAATGCCTGGAAATTCAGTTTGTAACATGGACTACATTTTGTACACCGCTCCCTCGGTATCAGAGCCTACGGAGCAAATGATAATGGTAGCGCCTTATGATGCGGTTATTCTTAGTACTTCGCCAGAAACGGATCGATCTCTTCCTGAACCGGAACCACCGCCTCTtaataatgtattaaaaaCGTCAGAACCTCCTTCGGATGTAACGACATACAAGAAATTACCTGATCTACCCTTGAGAAAAGATCAAGGCTCAGCACGGACTGATTTAACATTCTCCGACGTGTGGAAATTAAAGGCGAATGGTGCTGTGTTAGATTCGGTAGTCGGAGCATCGGACCTTGTGTTAGGTACAAGTGATTTAGAGGAAGGTTTATTGCTCACAGAGGAATTGCCTTCGATGTATTATCAAGATGATGTAGTAGGAACAGAGTATCAAGTACTGTTACTCGATTCAGTACCACCTGAAAGTACTATAAACTTGCGGGGACTTGAATAA
Protein Sequence
MIYKVSFDGGVVAVCGPLQSWLRGSQMSRKGTPSACKSKQIPRIFRNRRGLCSVRGWPHGEVGVVGGSVGYSQSSLLSASPDEEKTEDTNKKGKHKAETDDETAQYHHRVWIEGNQVTNGVVTSEPCIVDGIGKVADVETVADIEKWLKTRTESVSSMDLDAIKSGVEEGVDRYLGEELQHAFLEKDPDGLSIDIDLSDKKLNLGYDPLLQELQNEKLLDEKDSFILPEFQLDHLDPLALSPDDMMVAGEILPSTSAQPTLTVSNRDVEGLCAETEQASLLKKAMIVDGQESQNKSTQVVVDDLRVIDEVNKDVQLQKDNSPSENTMNLYVQDLSSENIVEELSGAKLVEGDSENVIIEQLKTKAKVKLEPRIIKKRKKIPETLEKKFESEIKICGEDVVDTEDGVMAVVAISTDKISNMTQIVINTGTEEQIYQGKTSELIEATGNFPKLPKIETSTVWNGTIEQSAENPNNQHELVISNALEELGITDDNLQPISVNEHGKVWLCPRDDCNRQFSKLYALKGHLLAHYGVRPFKCDFEGCAWAFYSEFKLKRHKETHLKRKDYICEVQGCNRRFTTIYNLWSHAKLHSRPNRILCQVPDCQEKFQTKRALELHMKSHDQSHAPYVCKHEGCGKRYYSSNALTSHQRCHSYKEVDVKCSWPGCGKVFDKPCRLKAHIRSHTGCKPYLCTFQGCQWAFSSSSKLKRHQKKHTNERKFVCDVPSCGKAFMRSEHLKEHRLTHKEGRYFQCFICNAKFSAKSSLYVHIKKHQVKEEVEANLHDTINGHKRSKLKETQCSRVNPVVKSKRKSIDLNINAACLNTSTVTENSEHINDANIRNNNENQTKDDTVPPQDQSKTLYHCPVETCTRSYTTKATLRAHMLKVHGTPVEECADKTSKRMPGNSVCNMDYILYTAPSVSEPTEQMIMVAPYDAVILSTSPETDRSLPEPEPPPLNNVLKTSEPPSDVTTYKKLPDLPLRKDQGSARTDLTFSDVWKLKANGAVLDSVVGASDLVLGTSDLEEGLLLTEELPSMYYQDDVVGTEYQVLLLDSVPPESTINLRGLE