Basic Information

Gene Symbol
-
Assembly
GCA_958510785.1
Location
OY294016.1:6926396-6930641[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 4 3.4e+02 2.4 0.0 3 16 222 235 221 237 0.91
2 15 0.021 1.8 9.5 2.8 1 23 409 432 409 432 0.95
3 15 1.6 1.3e+02 3.6 0.8 1 21 439 459 439 460 0.89
4 15 9.3e-06 0.00079 20.1 1.8 1 23 521 544 521 544 0.94
5 15 0.014 1.2 10.1 0.1 1 23 557 580 557 580 0.96
6 15 2.9e-05 0.0025 18.5 3.1 1 23 601 624 601 624 0.93
7 15 0.29 24 6.0 0.8 1 20 630 649 630 654 0.91
8 15 0.06 5.1 8.1 4.3 1 23 667 689 667 689 0.93
9 15 1.3 1.1e+02 3.9 0.1 3 23 697 718 695 718 0.87
10 15 1.1e-05 0.00094 19.8 1.6 1 23 732 754 732 754 0.99
11 15 4.3e-07 3.6e-05 24.3 1.6 1 23 760 782 760 782 0.98
12 15 0.002 0.17 12.7 0.9 1 23 788 810 788 810 0.98
13 15 0.0043 0.37 11.7 4.1 1 23 816 838 816 838 0.99
14 15 5e-06 0.00042 20.9 0.7 1 23 844 866 844 866 0.99
15 15 4.6e-05 0.0039 17.9 2.0 3 23 874 895 872 895 0.95

Sequence Information

Coding Sequence
ATGCTGACGCTCATTCTGCAAACTTCGGAAGGACAGCAGATCGAGTTGAACGTCCAGCCGGAGGATACGTTCGCCGATTTGAAGATACAATACTCCGACACCGACGGCTTGTCCGAGTCGCTGGAACGACTCATCACCAATGGAGCCACGGTGGAAGAAAATACGAGGATATTCGACTATGTGACTAGCAGcgcACACGAATGGTTCAGCGCGGGTGAAACGCCTGAGTCGGATGCGCAGACCTCGGAGCCTGCGGATCCTCGGACGAGGGTGAAAGAATGTTGCGCTCAAGGCTGCTCCAATTCCGAAGCCGTCACGCCTGGTAAACCATTTTTTCCTTTGCCTACAGATCACGAAAGGCTCTCCGCGTGCCTGACGGACGCGGGCAGGCTGGATCTGTACAGCCAGGTTCTCGGCTTAGACGCGGATAGTTaccagaaatattttttatgcggCAATCACATCGCTGAAATTTCTTTACCGACGGCGCGTGCTGCCGAGCCGACGTCCACGATATCGCTGTTGAAGCCGAAAAATGCGAGGGTTCAACCCGACGTGAGCAACGAACTGAAAAACGAGCTTCTAGAAGTCGATTCCGAAACGAGAGAGTCCGTTTTCGATCTACCCAGAACACCGGACAATTTCGAGCATCCCGGAATTCTTTGCCGTTTGTGCGGCGAAACTACCGCGAATCCTGTTCATTTGTACGCGGAGAAAGGAGAGAACTCTGACTCTGAGTACAGTCTCGCCGACAAGATCAACTTGTGCCTTCCCGTTACGgTGAGCGTGACGGATCCACTGCCGAAGCAGATATGCCGAGACTGCCAAGTTAAACTGAACGCTTGCCACGAACTCGCGGTATCCTCCCTCAGAACGGAGGACAAGCTTACTCTTCTCTTGCGAGAGAACAAGCTCTGCGCGAGCGGTGCTTCCGATCACCAGTGTCCTCTGTGTCTCGAGGGAGCGATGCGGATGGTAAAAAGAAGCGGCATCTACCGTAAGGAGGATCTACAGAAGGACCTAATTTTGTCGAACGACCGGAGACACGCGAGAAGCTCAGTCGGGACCGAGGAGAATGCAAAGAATTTCGACAACGTTATCTCGGACAGCGGTTCGCTTCCGGTGCCGGAAGGAGAATTCCCGTGCTCCATGTGCAACGAGAGGCTGATCGGCGTCACGGCTATCCGCTCGCACCGATGTCCAACCGATACAAAACATTCTCCTCACAACTGCGTCatctgcgataaaaaaaatttcgctcaTCCCCGCGAGCTCGAGCTTCACTATCGTCGGCACGGCATAAAGGAGGAGAAATTTTTCTGCGAGCATTGCAGCTACTCGTGCGAGGAGCTCGACGCGGTGACCGAGCACGTTAAAGCCTGCAGACCCGAGTTCTGGCAATTCCACTGCGACGCTTGTGACAAGACTCTCGCGAACGGCGAATCGCCGAACGATCACGATTGTCCCGGCGCTTCGTCGGATCCTCGCGAGGCCGAGGTGAAATTTTCACCGGAGCCGGAAGCGCCTAAGACACCGTCGAAGAAGAGGCAACCGACGCGCTACAATTGTCACTTCTGCGAGAAGCGATTCGCCCGAAAGGGAAGCCTGCAGAAGCACATATCGGCGGCGCACAACGACTCGATGGACGATCCAGCGGCCTCGAAGTGCTACAAGTGCAGAAGCTGCAACGAGGCCTTCGTGCGGGAGGCGGACGTCGCGATGCACGTGAACGTTCGTCACCTCGACGACTCGCGCTCCGGACACGAGCGCACCGTCGACGAATTGACGGTCGCGAGTCTGTACACCTGCGAGTACTGCGAGCGGTGCTTCACCACGCCGAGCTCCCTCCACGATCACCGCGAGGCCGAGCACGACAAAATTTCATGTTACTCATGCCCGACGTGCCTCGAGATATTCGACTCTCACAAGCGGCTCGCCGCCCACAAGAGTCTGCGATCTCATCACAAGCCTCTCGACTACCTCAACCTGAAGCAGCTCTACCTGTGCAGGTACTGCGACAAGACCTTTCTCCATCATTCTACACTATCGGCGCACGAGCTTCAGCATCGCGAGCTCGCGCCCTATCTTTGCAGACCGTGCGGTCTCAGCTTCGAGACTTACAGGGAGGTCGCCTCCCATCGGGACGTCGTTCATCCCTACCAGTCGGAGCTTCACGAGAGCTCCAGCCGATCATACAAGTGCCAGTACTGCGGCAAACTCTTCTCTCACGAGGTCGTTCTCGTCAAGCACATCAGAATGCACACCGGCGAGCGACCTCACAAGTGTTCCGTGTGCGGCAAGGGATTCTCGCAGAGCTCCGGCCTCTACACTCACATGAAGATCCACTCGGATCTGCGGCCCTACAATTGTCCGAGCTGTCCGCGCACATTCAAGATCAAGGGCGATCGCAACAATCACGTGAAGAAACACTCGGGCAATCGGCCGTACAAGTGCGAATTTTGCTCGAAGGCATTCATGACTCAGCACGTTTACAGTCAGCATCGGAGAATTCACACGAACGAGAGGCCGTACAAGTGCGAGATTTGCGGCGAGGCCTTTCGAAGGTCCTACGTAAGGACGGTCCACATGAGAAGGCACACAGGCGAAAAGCCGCATCTTTGCGATCTGTGCCCGAAGACCTATCGACAGCGCAGCGATCTCGTAAAGCATCGAAAAGTACAGCACGGCATAAGCGTTGCGACGAACAACGAGATCGTTTTTCCCGACGAACGCGAGGACGATCCTTACGACTCATTCGCGAAAGCTAACAAGATCGTCGAAACTGCGACCGGTAATTCGCTGCTGTTGAGCCTCTGA
Protein Sequence
MLTLILQTSEGQQIELNVQPEDTFADLKIQYSDTDGLSESLERLITNGATVEENTRIFDYVTSSAHEWFSAGETPESDAQTSEPADPRTRVKECCAQGCSNSEAVTPGKPFFPLPTDHERLSACLTDAGRLDLYSQVLGLDADSYQKYFLCGNHIAEISLPTARAAEPTSTISLLKPKNARVQPDVSNELKNELLEVDSETRESVFDLPRTPDNFEHPGILCRLCGETTANPVHLYAEKGENSDSEYSLADKINLCLPVTVSVTDPLPKQICRDCQVKLNACHELAVSSLRTEDKLTLLLRENKLCASGASDHQCPLCLEGAMRMVKRSGIYRKEDLQKDLILSNDRRHARSSVGTEENAKNFDNVISDSGSLPVPEGEFPCSMCNERLIGVTAIRSHRCPTDTKHSPHNCVICDKKNFAHPRELELHYRRHGIKEEKFFCEHCSYSCEELDAVTEHVKACRPEFWQFHCDACDKTLANGESPNDHDCPGASSDPREAEVKFSPEPEAPKTPSKKRQPTRYNCHFCEKRFARKGSLQKHISAAHNDSMDDPAASKCYKCRSCNEAFVREADVAMHVNVRHLDDSRSGHERTVDELTVASLYTCEYCERCFTTPSSLHDHREAEHDKISCYSCPTCLEIFDSHKRLAAHKSLRSHHKPLDYLNLKQLYLCRYCDKTFLHHSTLSAHELQHRELAPYLCRPCGLSFETYREVASHRDVVHPYQSELHESSSRSYKCQYCGKLFSHEVVLVKHIRMHTGERPHKCSVCGKGFSQSSGLYTHMKIHSDLRPYNCPSCPRTFKIKGDRNNHVKKHSGNRPYKCEFCSKAFMTQHVYSQHRRIHTNERPYKCEICGEAFRRSYVRTVHMRRHTGEKPHLCDLCPKTYRQRSDLVKHRKVQHGISVATNNEIVFPDEREDDPYDSFAKANKIVETATGNSLLLSL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2