Basic Information

Insect: Eutolmus rufibarbis
Gene Symbol: topi
Assembly: GCA_963920795.1
Location: OY987208.1:4066058-4069633[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.62 1e+02 4.8 0.4 2 21 169 187 168 188 0.91

2 10 1.1e-05 0.0018 19.8 2.1 1 23 248 270 248 270 0.97

3 10 0.013 2.1 10.1 0.1 2 23 368 389 367 389 0.97

4 10 0.86 1.4e+02 4.3 0.0 1 20 395 414 395 416 0.90

5 10 0.091 15 7.4 1.3 2 22 436 456 435 459 0.89

6 10 7.1e-07 0.00012 23.5 1.9 1 23 511 533 511 533 0.95

7 10 0.00085 0.14 13.8 1.0 1 23 539 564 539 564 0.96

8 10 0.35 57 5.6 1.7 1 23 570 592 570 592 0.88

9 10 4.2e-07 6.9e-05 24.2 0.3 3 23 600 620 598 620 0.98

10 10 0.0065 1.1 11.0 1.1 3 23 628 649 626 649 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.62	1e+02	4.8	0.4	2	21	169	187	168	188	0.91
2	10	1.1e-05	0.0018	19.8	2.1	1	23	248	270	248	270	0.97
3	10	0.013	2.1	10.1	0.1	2	23	368	389	367	389	0.97
4	10	0.86	1.4e+02	4.3	0.0	1	20	395	414	395	416	0.90
5	10	0.091	15	7.4	1.3	2	22	436	456	435	459	0.89
6	10	7.1e-07	0.00012	23.5	1.9	1	23	511	533	511	533	0.95
7	10	0.00085	0.14	13.8	1.0	1	23	539	564	539	564	0.96
8	10	0.35	57	5.6	1.7	1	23	570	592	570	592	0.88
9	10	4.2e-07	6.9e-05	24.2	0.3	3	23	600	620	598	620	0.98
10	10	0.0065	1.1	11.0	1.1	3	23	628	649	626	649	0.95

Sequence Information

Coding Sequence: ATGGACTACAACGACGAACAATATAATGCAGATATTCTGCTCgcggaaaaaatattttcccaacTCAAAGAGTATAATCCGGGAGAGTGCAATGAAAACGAACAACCGGATCATACCGGAAATAATGGAGTTTCAAAGGATATATCCTCTGAAGAGAAAGGTCCTTCTTCAGTGTTGAACTCTGGTGTCGAGGATCATTGCGAGATCTCTAACCAACAGTCTTTAGATCAGTGCGAGGTCTCTAACCAACCTGCTCCAGACCAGTGCGAGATGCCCACTCAGCCGTGCTCCGAAGAGCCGATGGACTTAACCAGCCAGTACGAGGGGCAGGTTACGATGAATGAAATATCGGagttaaaagaagaaaaagattCTGTCGTCGTTATCGACGAGGAGCACACCCAGCGATACTTGGATCTGCTTATTGCTTCACTGCCTCCCGAATGCTATtcagACGATGTAATCGTTGTGAAAGATTCCCTCAAGAGTGAAAGATGTGCCATAAAATGCACTAACTGCGAACAGATCTTCAACGAAGAGGCGTTCAATGAGCACATTTGCGACTACgatgaaaataagaatttcataaaagatGAAGAGCCGATAAAATGCTCCACAATTGAATTGGAGGAACCACCGTGTCTTCGCCAATTGCGAGAAAATAACACGcgaattagaaaatttctgAAGGACGAACTTAAGATAGACATCGGAGGTCCTACTAAAAGGAGTGATGGCCCGCACGAGTGCAACATGTGCGAAAGAAAATTCGTGCACGCCTCTGGACTGGCCAGGCACATGGAAAAGCATGCGATGGACCTGATCCCGATCACCACTAATACCACGCAGAGTGGAAGTGGACTGAAGGTGGTCATCAAGTGCCTGGTTTGTGGAAGGATACTTTTTGGGCATGTCGAAGCCATGGAGCACTTGAATGAAAACCACGCGCACTTGCTAATCGGCGATGAAACCGACAGTGAAAAGGATTTACCAAGTGAAAGAATTGATGAGGCGattgagtttattttaaaagagACAACCGATGAGCAAACAGACAAAACGAACCCATACTTAAAAGTTGTGATCTTGACCTGCACTTTGCAGTGTGAATTTTGTGATTTACTATTCTCAGAAGTCTCAGATCTTCTAAATCATGCTTCGACCCACGATCCCATGAGGGGTTTTGAGTGCTCCTCTTGTGGGATAAACGTTTCAACGGCTAAAGAAATATTCCTCCACTGGCAAGCAGAATGTCCCTACGTCAGagatgaattaaaaaagataaacaaTTTGCAGAAGTATCTCGTTTGTAACGTTTGTGAGAACAAGTACACTTCACACGAGCAATTGTACGATCACAGATACACCGAATTTCATTTATTCCCAAGGCTGAATAGAAGTATGGGAATTATGCAAGTTTGCTGTGAGTACTGTGGGAGTTTTCACGACAGTGCTAAAGCAATTATGCGACACCACGAGGAGAAACATATGAAAAAGGTTAAAAAGGAGACGACAGCGAAATATAGGCAGTATCTTTGCGATGTTTGCGGGAAGTCGTATACTCAATCAAGTCATTTGTGGCAGCATCTGCGTTTTCATAGAGGAGTTAAGCCATTTGCCTGCAAGGAGGCAGGCTGTAATCGCCGATTTACAATCCGGCCAGATCTTAATGATCACATCCGAAAATGCCACACAGGAGAGCGCCCGTATCATTGTCTTGTATGCGGGAAACGTTTCCTCACCGGATCTGTTTTTTACCAACATCGATTAATTCATCGTGGTGAGAGGCGGTACGGTTGTGATGAATGCGGGAAGCGATTCTATCGCGCAGATGCTCTGAAAAACCATCAACGAATTCATACTGGTGAAAAACCTTACGGCTGCATGTATTGCACGAAAAATTTCAGACAACGTGGAGATCGCGACAAGCATATTCGAGCTCGACATGCTAATTTAGATGCAAACGCGAGATcgtataatatgaaaaataaggACAGTTCGAGCAATGGTGTAGTGTTTGTTGGAAATGTCGCGTTCCCGACTAGCATGTTTAAGCCAATGATGAGAGATATTGACGAATGCCCAAACATGTATTAA
Protein Sequence: MDYNDEQYNADILLAEKIFSQLKEYNPGECNENEQPDHTGNNGVSKDISSEEKGPSSVLNSGVEDHCEISNQQSLDQCEVSNQPAPDQCEMPTQPCSEEPMDLTSQYEGQVTMNEISELKEEKDSVVVIDEEHTQRYLDLLIASLPPECYSDDVIVVKDSLKSERCAIKCTNCEQIFNEEAFNEHICDYDENKNFIKDEEPIKCSTIELEEPPCLRQLRENNTRIRKFLKDELKIDIGGPTKRSDGPHECNMCERKFVHASGLARHMEKHAMDLIPITTNTTQSGSGLKVVIKCLVCGRILFGHVEAMEHLNENHAHLLIGDETDSEKDLPSERIDEAIEFILKETTDEQTDKTNPYLKVVILTCTLQCEFCDLLFSEVSDLLNHASTHDPMRGFECSSCGINVSTAKEIFLHWQAECPYVRDELKKINNLQKYLVCNVCENKYTSHEQLYDHRYTEFHLFPRLNRSMGIMQVCCEYCGSFHDSAKAIMRHHEEKHMKKVKKETTAKYRQYLCDVCGKSYTQSSHLWQHLRFHRGVKPFACKEAGCNRRFTIRPDLNDHIRKCHTGERPYHCLVCGKRFLTGSVFYQHRLIHRGERRYGCDECGKRFYRADALKNHQRIHTGEKPYGCMYCTKNFRQRGDRDKHIRARHANLDANARSYNMKNKDSSSNGVVFVGNVAFPTSMFKPMMRDIDECPNMY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01256644; iTF_00628671; iTF_01049925; iTF_01461422; iTF_01184079; iTF_00937582; iTF_00936823;
90% Identity: iTF_00937582;
80% Identity: -