Ehis031262.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Eustalomyia histrio
Gene Symbol
-
Assembly
GCA_949748255.1
Location
OX456525.1:138575180-138589453[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 1.8e-07 1.9e-05 26.3 1.4 2 23 210 231 210 231 0.97
2 9 2.3e-07 2.4e-05 26.0 0.5 1 23 237 259 237 259 0.98
3 9 2.2e-07 2.3e-05 26.0 0.6 1 23 265 287 265 287 0.98
4 9 1.2e-05 0.0012 20.5 0.5 4 23 298 317 293 318 0.92
5 9 0.00012 0.013 17.4 2.9 1 23 323 345 323 345 0.97
6 9 6e-05 0.0063 18.3 3.6 1 23 351 374 351 374 0.98
7 9 0.0002 0.021 16.7 2.0 1 23 380 402 380 402 0.98
8 9 1.6e-05 0.0017 20.1 1.2 1 23 407 429 407 429 0.98
9 9 0.005 0.53 12.3 0.3 2 23 436 460 435 460 0.94

Sequence Information

Coding Sequence
ATGAAACTGGCAGTTAAAAACCATTCATCCCAATGGGGATGGGCTAAGCTAAACAGATTACAAAGGGCTGCTGCTCTTGGTATTACCGATGCTATGTGTACCACACGTGGAGACGCTCTTGATGTCATCTCTCCCCTGGATCTTCATGTACAGGGCGAGGCTATGATATCAATATGCCGACTCGGAAATAATGGAAACTGGTATATGGGTTGCGACACAGGGCATAGTCTAATCTTGTTTCAAGTTCCCGGCTATAACATACCCACCTGTGTAAAGTGTTCGGAACATTTGACAAACAGCGGTAATGGTTTTTATCAGGCAGTAGCTGCTACTGCAGCAAGTGGTCAACCGGCACTGGCGGCGGCAACAGCTGCTACAAATAATACCAACAATACAACAGCCAATAGTTTGAATCAACAACAAATGCCTcaacaacaattacaaaattctacAAATTCAACTAATAGTTTACAATCGCAGGACGATTCAGAAGATAGAGTTCAACAACAAACACGCCGTCCTCGTAAAAACGGTgttaataaaatacaacaaatcaCGATGTCCTCCTATGAATTGGAGAAGACCATACAACATTTAGATgTGGACTTAATATTTAATGAAGAAGGATCATGTCCTTTAtgcaataaaacattttcaaggAAATCCTCCTTGATAACACATATACGTAATCATGCAGctgaaagaaaatttgtatgcaattaTTGTAATAAAGGTTTTACTCAAGCGGCCAATTTAAGAAATCATGAACGCATACACACCAATGATCGTCCTTATGTCTGTGGAGATTGTGGTAAAACATTTACACAGATAACGAATCTAAATAATCATCGGCGCTTGCATACCGGCGAACGTCCTTTTGTTTGCATTGAACCCGAATGTGGTCGTTCATTTGCCCAAGTAACAAATCTGAATAATCATATGAAAACCCACCATAAAGTCCAGCAGTACTGTTGCAATCAATGTCCGAAAAAATTCACACAAGTCACCTCGCTTAATCAACATTTACAAGCTCATGCCGGCATAACCGGCTACTATTGCCCACGATGTCCGGAAAAGACATTTAAGCAGCAATCACAACTACACACCCACATGAAATCCCATGGTCTTCAATATCCGTTTGAATGTTCAAAATGTGATGAGAAATTCTTGCAGCAGGCCCACTTGGAGCAACATCTGAAGATGCATGATGAGTTCAAATTCAAATGCAATATTTGTCCTAGTTCATTCAATCAGGAGTCATTACTTAAGAAACATGAACAACGTCATTTAGAGGGCAGGTACCTCACTTGTCCTGTGGCCAATTGCAATGAGGCCTTTGCTGTTCGCCAACATCTCtcaaaacatttgttaaataGTCATTCGCATACCGAACTACCGCCTCCAAAACGTTCTAAGAAATGTATAACATTACAACCGCCTCAACAACCTGTTACTATGGTTGGCCAGCCATTGTCCTTACAACATGCTCCTCAACGTGGTCGTcctcctaaaaataaaaataagcctgttataaataatgtTAGTGGTTTGTCAATACCACAACAATTAAATCAACATAttcagcaacaacagcagcaagcTCAAGCTCAACAACAAGCACAggcacaacaacagcaacaacagttactacaacagcagcaacatcaATTAATTTTGGGTAATCAAGTTAAAGTTCGTTATATACCCAATAAtcagattaaataa
Protein Sequence
MKLAVKNHSSQWGWAKLNRLQRAAALGITDAMCTTRGDALDVISPLDLHVQGEAMISICRLGNNGNWYMGCDTGHSLILFQVPGYNIPTCVKCSEHLTNSGNGFYQAVAATAASGQPALAAATAATNNTNNTTANSLNQQQMPQQQLQNSTNSTNSLQSQDDSEDRVQQQTRRPRKNGVNKIQQITMSSYELEKTIQHLDVDLIFNEEGSCPLCNKTFSRKSSLITHIRNHAAERKFVCNYCNKGFTQAANLRNHERIHTNDRPYVCGDCGKTFTQITNLNNHRRLHTGERPFVCIEPECGRSFAQVTNLNNHMKTHHKVQQYCCNQCPKKFTQVTSLNQHLQAHAGITGYYCPRCPEKTFKQQSQLHTHMKSHGLQYPFECSKCDEKFLQQAHLEQHLKMHDEFKFKCNICPSSFNQESLLKKHEQRHLEGRYLTCPVANCNEAFAVRQHLSKHLLNSHSHTELPPPKRSKKCITLQPPQQPVTMVGQPLSLQHAPQRGRPPKNKNKPVINNVSGLSIPQQLNQHIQQQQQQAQAQQQAQAQQQQQQLLQQQQHQLILGNQVKVRYIPNNQIK