Basic Information

Insect: Drosophila yakuba
Gene Symbol: Rfx2_1
Assembly: GCA_016746365.1
Location: NC:11978452-11995502[-]

Transcription Factor Domain

TF Family: RFX
Domain: RFX domain
PFAM: PF02257
TF Group: Basic Domians group
Description: RFX is a regulatory factor which binds to the X box of MHC class II genes and is essential for their expression. The DNA-binding domain of RFX is the central domain of the protein and binds ssDNA as either a monomer or homodimer [1]. It recognize X-boxes (DNA of the sequence 5'-GTNRCC(0-3N)RGYAAC-3', where N is any nucleotide, R is a purine and Y is a pyrimidine) using a highly conserved 76-residue DNA-binding domain (DBD) [2].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 2e-37 6.9e-34 116.7 0.1 3 78 398 473 396 474 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	2e-37	6.9e-34	116.7	0.1	3	78	398	473	396	474	0.97

Sequence Information

Coding Sequence: ATGACCACACGCCTGGCACCGCAGCGCCAGTTCATCATCTCGACGCGCTCCGCCATCGTGGATGCCACCTCGCCACCAGAGGACTcagtggaggagcagcagcagctgaccGTCGAGGTGGAGAGCGCCACCACCGGACTCACGGGGGGCAGCACCACCAATAGCACCACATCGCCACCGCCGCATGCCGAGCAGTTCGAGTTCTGCACGGAGGATGGAGTCGTTGTCTCCGCCACACTGGAGGATGTCATGACACAGGTAAAGCTTCTCCCCCTCTTGCAGAACTGCCAGCTCTTGCAGAAGAAACTAGtcgacgaggacgacgatTCGACGGGAGCAGGAGCAACCGGTGCCGAGCAGCTGGAGGTCATCCGCGTCGTGCTGCCCATGGATGCCGAGGACTCGAGCAGCGATGCCCATCTGCATGGGCATGTGgtgaacagcagcagcgacaccATGGGCACCATTACCACCACGGAGCCGAATGGAACCACCGTGACCCACTCCATACCCATTCACAGCATGGCCGATCTGGAGGCGATCAAGGATGGCGTCGATCTCGCCCAGCAAGTGGCCAATGGCCAGGTGACCGTGGTCCAGACCACCGAGGATGACGATGGAACGCCCTTCATCACTGTGACGGTTTCGGGCCAGGAGCAGAACTACCAAGTGCAATATGTGGACTCAGAGCTGTACCACAGCAACTCCAGCCAGACGCAAATGACGTACCCATTCTGCCCGGTGGGGGACTACCAGGGCAATGGCCAGACGGCCTACTACTCGACTACGGGTCAGTACGGAGCCACCTCGTCGGCCGGAGGCTCCTCGAATGGGGCGCACTCCACGACGCTGCCGTACCTGGTGCCCGTGGAGGAGGGCATCCTCCTCAATGGCTCCGCACACTCGctgtcgcagtcgcagtcacaGTCGCAGTCGCATGGACGCGATTCGCCGCACAGCCTGACGGTGAGTAGCAGGGATTGGGAGCGGGATGCGGACCGGGTGAACGGAACTAATCGCCACTGGGTGCAGGAGGTCGCGTACATCCAGGAGGCGCAGAGCACGCCCCAGACGCCCACCTCGACGACCACAACCCACTCGGCTAGCGGCGGCAGCCTGGGAACGGGCGGCGGAGGCGCCTCCCCGGATTCCGACCAGAGTGCGctcggcagcagcaacaagattGCCTCGGCAACGATCAAGTGGCTGTCGCGCAACTACGAAACGGCGGATGGGGTGAGCCTGCCCAGAAGCACGCTGTACAACCATTACATGCAGCACTGCAGCGAGCACAAGCTGGAACCCGTGAATGCGGCCAGCTTCGGCAAGCTGATACGTTCCGTGTTCTCCGGACTGCGCACACGTCGCCTGGGCACGCGCGGCAACTCCAAGTACCACTACTATGGCATCCGCATCAAGCCCGGCTCGCTCCTAAACAGCCAGGCGATGGACGACAAGCAGATGCTGGCCGCCGGCTACGGACCATCCTCGGACGGATCCGGCGGACCGGGCAGCGGACCCTTGGTTAGCGTCACCAGCAGCACCGCCGGACAGCTGGCCGGCTCCAATGGATTGGGCGGTGGCCATGGCCAGCGGCACAGCGGCGGCACCAAGAAGCACACCTTCAAGCCGGAGACCTACGAGGCGTGCATTCAgTACATCGGCGATGGAACCAGTGCCCTGCCCTCGTTTCCGCCCATCGAGCTGAACCACAGTTTCAACAGCGAACTGACTCTGGAGGACGTGGACACCTTCCGTGCGCTGTACCGTGAGCACTGCGAGTCCTTCCTGGACGCCGTGCTCAATCTGGAGTTCAACACCGTGGAGTTCCTGCTGCGCGACTTCTGGCGGgccagcgacaacaacaatcTGGACGAGTGCGAGGAGGAGAAGTATCTGAGCAAGACGAAGCTGTATCTGTTGTGCCACTGCGCAGAAGTGCAGAAGTTCGTGCGAGAGGTGGACTATCAGTTCTACCAGAACACCGTCGATGTCATCATACCAGATGTGCTCCGCTCCATACCGAACGCCCTGACCCAGGCCATTAGGAACTTCGCCAAGAACCTGGAGATCTGGCTGTGCGAGAGCATGCTGGGCGTGCCGGAGCAGCTTGCCCAGATCAAGACCAGTGCCGTCTCGGCCTTCTGCCAAACGCTGCGGCGCTACACCTCGCTGAATCACCTGGCGCAGGCGGCTCGAGCAGTGCTCCAGAATGGCGCCCAGATCTCCCAGATGCTAAGCGATCTCAATCGCGTCGACTTTCACAATGTGCAGGAGCAAGCTGCCTGGGTGAGTCAGTGTGCGCCCGCCGTGGTCCAGCGCCTGGAGAGCGACTTCAAGGCCGctctgcagcagcagagctCCCTGGAGCAGTGGGCCAGCTGGCTGCAACTGGTGGTGGAGTCGGCCATGGAGGAGTACAACGGGAAGCCGACTTATGCCAGAGCCGCCCGCCAGTTCCTGCTGAAGTGGAGCTTTTACAGCTCCATGATCATACGGGACCTGACACTGAGATCCGCATCTAGTTTCGGCAGCTTCCACCTGATTCGCCTGCTGTTCGATGAGTACATGTTCTACCTGGTGGAGCACAAAATCGCCGAGGCACAAGACAAAACCGCCATTGCGGTTATCTGCGAAAGAATGAAAAAGGACATGGACTTTGAGTTCGAGTGCCAGTTCGCCTACATCACCAGCGACGCGGAGCACCAGACGACTCCGAGCTCGGCCAGCAGCGGAGGCGACGTGGGCAACGAGGCGAAGCGACTGAAGCAGGAATGA
Protein Sequence: MTTRLAPQRQFIISTRSAIVDATSPPEDSVEEQQQLTVEVESATTGLTGGSTTNSTTSPPPHAEQFEFCTEDGVVVSATLEDVMTQVKLLPLLQNCQLLQKKLVDEDDDSTGAGATGAEQLEVIRVVLPMDAEDSSSDAHLHGHVVNSSSDTMGTITTTEPNGTTVTHSIPIHSMADLEAIKDGVDLAQQVANGQVTVVQTTEDDDGTPFITVTVSGQEQNYQVQYVDSELYHSNSSQTQMTYPFCPVGDYQGNGQTAYYSTTGQYGATSSAGGSSNGAHSTTLPYLVPVEEGILLNGSAHSLSQSQSQSQSHGRDSPHSLTVSSRDWERDADRVNGTNRHWVQEVAYIQEAQSTPQTPTSTTTTHSASGGSLGTGGGGASPDSDQSALGSSNKIASATIKWLSRNYETADGVSLPRSTLYNHYMQHCSEHKLEPVNAASFGKLIRSVFSGLRTRRLGTRGNSKYHYYGIRIKPGSLLNSQAMDDKQMLAAGYGPSSDGSGGPGSGPLVSVTSSTAGQLAGSNGLGGGHGQRHSGGTKKHTFKPETYEACIQYIGDGTSALPSFPPIELNHSFNSELTLEDVDTFRALYREHCESFLDAVLNLEFNTVEFLLRDFWRASDNNNLDECEEEKYLSKTKLYLLCHCAEVQKFVREVDYQFYQNTVDVIIPDVLRSIPNALTQAIRNFAKNLEIWLCESMLGVPEQLAQIKTSAVSAFCQTLRRYTSLNHLAQAARAVLQNGAQISQMLSDLNRVDFHNVQEQAAWVSQCAPAVVQRLESDFKAALQQQSSLEQWASWLQLVVESAMEEYNGKPTYARAARQFLLKWSFYSSMIIRDLTLRSASSFGSFHLIRLLFDEYMFYLVEHKIAEAQDKTAIAVICERMKKDMDFEFECQFAYITSDAEHQTTPSSASSGGDVGNEAKRLKQE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00607554; iTF_00592131; iTF_00539400; iTF_00504428; iTF_00591446; iTF_00486315; iTF_00565121; iTF_00594287; iTF_00617377; iTF_00524162; iTF_00525634; iTF_00475688; iTF_00565833; iTF_00487749; iTF_00579729; iTF_00538706; iTF_00589993; iTF_00606057; iTF_00527051; iTF_00612555; iTF_00561487; iTF_00545715; iTF_00503739; iTF_00614651; iTF_00550005; iTF_00481297; iTF_00491256; iTF_00491960; iTF_00608922; iTF_00489120; iTF_00489824; iTF_00613248; iTF_00615328; iTF_00602325; iTF_00604578; iTF_00507357; iTF_00600799; iTF_00514633; iTF_00480622; iTF_00473524; iTF_00471350; iTF_00611138; iTF_00916931; iTF_00580426; iTF_00603092; iTF_00563638; iTF_00574552; iTF_00580427; iTF_00535803; iTF_00484187; iTF_00914235;
90% Identity: iTF_00539400;
80% Identity: -