g1037.t2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila pseudoobscura
Gene Symbol
Rfx2
Assembly
GCA_009870125.2
Location
CM020868.1:7673846-7678255[+]

Transcription Factor Domain

TF Family
RFX
Domain
RFX domain
PFAM
PF02257
TF Group
Basic Domians group
Description
RFX is a regulatory factor which binds to the X box of MHC class II genes and is essential for their expression. The DNA-binding domain of RFX is the central domain of the protein and binds ssDNA as either a monomer or homodimer [1]. It recognize X-boxes (DNA of the sequence 5'-GTNRCC(0-3N)RGYAAC-3', where N is any nucleotide, R is a purine and Y is a pyrimidine) using a highly conserved 76-residue DNA-binding domain (DBD) [2].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 8.6e-38 5.8e-34 116.7 0.1 3 78 317 392 315 393 0.97

Sequence Information

Coding Sequence
ATGCATTCGCGGTACGGCTTTGACTATCAGACGCGtcaccaccaacagcagcagcagcagcacctgcaCCATCATCACCAGCTCGAGTCGTCGCCGCTGAACTACACGAATCTCCTCGAGAAGTGCCGCTGCAAGCAGTCGCTGCCAGTCAGCGCCAcccagccgccgccgccgacacTGCCACccgcccagctccagctgcagctgcaccatcatcatcaccaccatcatcaccaGACGTTCGTGGCCACGGCCAGTGCCGCCGCCTGCTACAGCAGCTCCTCGACCATTGAACCTGCGGCTGGCTCCCCAGCATCCGCAGCCTCGTTCtccacagccgcagcctccTGTGCGGCCGCCTCCAACTCGGTCTCGGCGGGTCTGGGCACCAGCACAGGCTCTGTGGCGAATCTATCCGCTACAACCACAACCAtgtaccaccaccaccacagacGTCACAACAATTTGTCCTATTGCGGTGTTTCCGGCCAGGAGCAGAACTACCAAGTGCAGTATGTGGACTCGGAGCTCTACCACAGCAACTCCAGCCAGACGCAAATGACATATCCGTTCTGCCCGGTGGCCGACTACCAGGGCAATGGTCAGACATACTACTCGACCGCGTCGACGGGCCAGTATGCGGCGACGACGCAGTCGGCTGGGGGCAATACGGCGGGCAATGCGGCCCACTCCACGACGCTGCCCTACCTGGTGCCCGTGGAGGAGGGCCTGCTGCTGAACGGCTCCTCGCAGTCGCACAGCCGCGACTCGCCGCACAGCCTGACGCACGAGGTTGCCTACATCCAGGAGGCGCAGAGCACGCCCCAGACGCCCACCTCGACGACGACCACCAACTCGGCCAGCGGCGGCAGCCTCGGAACGGGCGGCGGTGGCGCCTCCCCCGATTCGGACCAGAGCGCGctcggcaacagcaacaagattGCCTCGGCAACGATCAAATGGTTGTCACGCAACTACGAGACGGCCGACGGTGTCAGCCTGCCCAGGTCCACCCTGTACAACCACTACATGCAGCACTGCAACGAGCAGAAGCTGGAGCCGGTGAATGCAGCCAGCTTCGGCAAGCTGATACGCTCCGTGTTCTCCGGCCTGCGCACACGTCGCCTGGGCACGCGCGGCAACTCCAAGTACCACTACTATGGCATCCGCATCAAGCCCGGCTCGCTGCTGAACCATCACTCCATGGAGGACTCCAAGTCGATGCACGGCTACGGGCCATCCTCCGGGGCCAACGGGGCCCTGGTaagcgtcagcagcagcacgtcCGGTCAAATGGCGGGCTCCAACGGCAGCGTGGGCATGGCCGGTTCCGCCGGCCAGCGGAACGGCACGTCCAAGAAGCACAGCTTCAAGCCCGAGACCTACGAGGCATGCATCCAATACATTGGCGACGGTAGCAGCGCCCTGCCCTCGTTTCCGCCCATCGAGCTGAGCCACAGCTTCAGCAGCGAGCTCACGCTGGAGGATGTGGACACGTTCCGGGCACTGTACCGCGAGCATTGCGAGTCCTTTCTGGATGCCGTGCTGAATCTGGAATTCGGCACCGTGGAGTTTCTGCTGCGCGACTTCTGGCGGtccagcgacaacaacaacctggACGAGTGCGAGGAGGAGAAGTACTTGAGCAAGACAAAGCTGTATCTGTTGTGCCACTGCGCAGAAGTGCAAAAGTTCGTACGCGAGGTGGACTATCAGTTCTACCAGAACACAGTGGATGTCATCATACCCGATGTGTTGCGCTCCATACCGAACGCCCTGACCCAGGCCATACGCAATTTCGCCAAGAACctggagctgtggctgtgcgAGAGCATGATGGGTGTGCCGGAGCAGTTGGCCCAGATCAAGACCAGCGCCGTATCCGCCTTTTGCCAGACGCTGCGTCGCTACACCTCGCTCAATCATCTGGCGCAGGCCGCACGAGCTGTGCTCCAGAACGGGGCCCAGATCTCCCAGATGTTGAGTGATCTGAACCGCGTGGATTTCCACAATGTGCAGGAACAGGCCGCCTGGGTGAGTCAGTGTGCCCCGGCTGTGGTTCAGAGATTGGAGAGCGACTTCAAGGCcgccctgcagcagcagagctcGCTGGAGCagtgggccagctggctgCAGCTCGTGGTCGAGTCGGCCATGGAGGAGTACACGGGCAAGCCGACATATGCGCGGGCCGCCCGCCAGTTCCTGCTCAAGTGGAGCTTCTACAGCTCGATGATCATCCGGGACTTGACGCTGCGCTCGGCCTCGAGCTTCGGCAGCTTCCACCTGATAAGGCTTCTGTTCGACGAGTACATGTTCTATCTGGTGGAGCACAAGATAGCCGAGGCGCAGCAGAAGACGGCCATAGCGGTCATATGCGAACGCATGAAGAAAGAGATGGACTTTGAATTCGAATGCCAGTTCGCGTACATCACCAGCGAAACGGAGCAGCAGAATACCCCCAGCTCGGTCAGCGGCGGGGATGTTGGCAACGAGGCGAAGCGACTGAAGCAGGAATGA
Protein Sequence
MHSRYGFDYQTRHHQQQQQQHLHHHHQLESSPLNYTNLLEKCRCKQSLPVSATQPPPPTLPPAQLQLQLHHHHHHHHHQTFVATASAAACYSSSSTIEPAAGSPASAASFSTAAASCAAASNSVSAGLGTSTGSVANLSATTTTMYHHHHRRHNNLSYCGVSGQEQNYQVQYVDSELYHSNSSQTQMTYPFCPVADYQGNGQTYYSTASTGQYAATTQSAGGNTAGNAAHSTTLPYLVPVEEGLLLNGSSQSHSRDSPHSLTHEVAYIQEAQSTPQTPTSTTTTNSASGGSLGTGGGGASPDSDQSALGNSNKIASATIKWLSRNYETADGVSLPRSTLYNHYMQHCNEQKLEPVNAASFGKLIRSVFSGLRTRRLGTRGNSKYHYYGIRIKPGSLLNHHSMEDSKSMHGYGPSSGANGALVSVSSSTSGQMAGSNGSVGMAGSAGQRNGTSKKHSFKPETYEACIQYIGDGSSALPSFPPIELSHSFSSELTLEDVDTFRALYREHCESFLDAVLNLEFGTVEFLLRDFWRSSDNNNLDECEEEKYLSKTKLYLLCHCAEVQKFVREVDYQFYQNTVDVIIPDVLRSIPNALTQAIRNFAKNLELWLCESMMGVPEQLAQIKTSAVSAFCQTLRRYTSLNHLAQAARAVLQNGAQISQMLSDLNRVDFHNVQEQAAWVSQCAPAVVQRLESDFKAALQQQSSLEQWASWLQLVVESAMEEYTGKPTYARAARQFLLKWSFYSSMIIRDLTLRSASSFGSFHLIRLLFDEYMFYLVEHKIAEAQQKTAIAVICERMKKEMDFEFECQFAYITSETEQQNTPSSVSGGDVGNEAKRLKQE*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00618897;
90% Identity
iTF_00487049; iTF_00517449; iTF_00474251; iTF_00580427; iTF_00535803;
80% Identity
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