Dper006035.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila persimilis
Gene Symbol
Rfx2
Assembly
GCA_003286085.2
Location
NW:7733663-7750682[+]

Transcription Factor Domain

TF Family
RFX
Domain
RFX domain
PFAM
PF02257
TF Group
Basic Domians group
Description
RFX is a regulatory factor which binds to the X box of MHC class II genes and is essential for their expression. The DNA-binding domain of RFX is the central domain of the protein and binds ssDNA as either a monomer or homodimer [1]. It recognize X-boxes (DNA of the sequence 5'-GTNRCC(0-3N)RGYAAC-3', where N is any nucleotide, R is a purine and Y is a pyrimidine) using a highly conserved 76-residue DNA-binding domain (DBD) [2].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 6.5e-38 4.6e-34 116.5 0.1 3 78 405 480 403 481 0.97

Sequence Information

Coding Sequence
ATGACCACGCGCCTGGCACCCCAGCGACAGTTCATCATCTCGACGCGCTCTGCCGTGGCCagtgccagcgccagcgccgtCGTTGTGGATGCCATCCAGGCGGAGCCAGCggaggagctgcagcagctgccggAGGATGTGCTGACCGTCGAGGTGGagaacaccaacagcaacaacaacctcCCAACCGCTGCGACCTCCGTAACGACATCGCCCACGCATGCCGAGCAGTTCGAGTTCTGCACGGAGGATGGTGTTGTTGTCTCCGGCACCCTGGAGGATGTTATGACCCAGAACTGCCAGCTCCTGCAGAAGAAACTAAGCGAAGGCGACGACTCTGTGACGGGCACCGCAACCGGAGCCGAGCAGCTGGAGGTGATACGCGTCGTACTGCCCATGGATGCCAGCGACTCGAGCAACGAGGCCCACATGCCCATCCACGGGCATGTggtcaacagcagcagcgacatcGGAGGCACCATCACCACCACAGAGCCGAATGGCAGCACCATCACCCATTCCATACCCATACACAGCATGGCCGACCTGAGCGCCATCAAGAACGGCGTCGATCTGGCCCAGCAGGTGGCCAATGGCCAGGTGACCGTGGTGCAGGCCACCGAGGATGATGACGGCACGCCATTCATCACCGTTACGGTTTCCGGCCAGGAGCAGAACTACCAAGTGCAGTATGTGGACTCGGAGCTCTACCACAGCAACTCCAGCCAGACGCAAATGACATATCCGTTCTGCCCGGTGGCCGACTACCAGGGCAATGGTCAGACATACTACTCGACCGCGTCGACGGGCCAGTATGCGGCGACGACGCAGTCGGCTGGCGGCAATACGGCGGGCAATTCGGCCCACTCCACGACGCTGCCCTACCTGGTGCCCGTGGAGGAGGGCTTGCTGCTGAACGGCTCCTCGCAGTCGCACAGCCGCGACTCGCCGCACAGCCTGACGGTGAGTAGGGAGCGGGGACGGGAGTGGGAGCCACCTGAGCCAACTGTGACTACATTGACTAACCCTTGGGCCACCCTTGGGCTGCAGCACGAGGTTGCCTACATCCAGGAGGCGCAGAGCACGCCCCAGACGCCCACCTCGACGACGACCACCAACTCGGCCAGCGGCGGCAGCCTCGGAACGGGCGGCGGTGGCGCCTCCCCCGATTCGGACCAGAGCGCGctcggcaacagcaacaagatTGCCTCGGCAACGATCAAATGGTTGTCACGCAACTACGAGACGGCCGACGGTGTCAGCCTGCCCAGGTCCACCCTGTACAACCACTACATGCAGCACTGCAACGAGCAGAAGCTGGAGCCGGTGAATGCAGCCAGCTTCGGCAAGCTGATACGCTCCGTGTTCTCCGGCCTGCGCACACGTCGCCTGGGCACGCGCGGCAACTCCAAGTACCACTACTATGGCATCCGCATCAAGCCCGGCTCGCTGCTGAACCATCACTCCATGGAGGACTCCAAGTCGATGCACGGCTACGGGCCATCCTCCGGGGCCAACGGGGTCCTGGTgagcgtcagcagcagcacgtCCGGTCAGATGGCCGGCTCCAACGGCAGCGTGGGCATGGCCGGATCCGCCGGCCAGCGGAACGGCACGTCCAAGAAGCACAGCTTCAAGCCCGAGACCTACGAGGCATGCATCCAATACATTGGCGACGGTAGCAGCGCCCTGCCCTCGTTTCCGCCCATCGAGCTGAGCCACAGCTTCAGCAGCGAGCTCACGCTGGAGGATGTGGACACGTTCCGGGCACTGTACCGCGAGCATTGCGAGTCCTTTCTGGATGCCGTGCTGAATCTGGAATTCGGCACCGTGGAGTTTCTGCTGCGCGACTTCTGGCGGTCCAGCGACAACAACAACCTGGACGAGTGCGAGGAGGAGAAGTACTTGAGCAAGACAAAGCTGTATCTGTTGTGCCACTGCGCAGAAGTGCAAAAGTTCGTACGCGAGGTGGACTATCAGTTCTACCAGAACACAGTGGATGTCATCATTCCCGATGTGCTGCGCTCCATACCGAATGCCCTGACCCAGGCCATACGCAATTTCGCCAAGAATCTGGAGCTGTGGCTGTGCGAGAGCATGATGGGTGTGCCGGAGCAGTTGGCCCAGATCAAGACCAGCGCTGTATCCGCCTTTTGCCAGACGCTGCGTCGCTACACCTCGCTCAATCATCTGGCGCAGGCCGCACGAGCTGTGCTCCAGAACGGAGCCCAGATCTCCCAGATGTTGAGTGATCTGAACCGCGTGGATTTCCACAATGTGCAGGAACAGGCCGCCTGGGTGAGTCAGTGTGCCCCGGCTGTGGTTCAGAGATTGGAGAGCGACTTCAAGGCCgccctgcagcagcagagctCGCTGGAGCAGTGGGCCAGCTGGCTGCAGCTCGTGGTCGAGTCGGCCATGGAGGAGTACACGGGCAAGCCGACATATGCGCGGGCCGCCCGCCAGTTCCTGCTCAAGTGGAGCTTCTACAGCTCGATGATCATCCGGGACTTGACGCTGCGCTCGGCCTCGAGCTTCGGCAGCTTCCACCTGATAAGACTTCTGTTTGACGAGTACATGTTCTATCTGGTGGAGCACAAGATAGCCGAGGCGCAGCAGAAGACGGCCATAGCGGTCATATGCGAACGCATGAAGAAAGAGATGGACTTTGAATTCGAGTGCCAGTTCGCGTACATCACCAGCGAAACGGAGCAGCAGAATACCCCCAGCTCGGTCAGCGGCGGGGATGTTGGCAACGAGGCGAAGCGACTGAAGCAGGAATGA
Protein Sequence
MTTRLAPQRQFIISTRSAVASASASAVVVDAIQAEPAEELQQLPEDVLTVEVENTNSNNNLPTAATSVTTSPTHAEQFEFCTEDGVVVSGTLEDVMTQNCQLLQKKLSEGDDSVTGTATGAEQLEVIRVVLPMDASDSSNEAHMPIHGHVVNSSSDIGGTITTTEPNGSTITHSIPIHSMADLSAIKNGVDLAQQVANGQVTVVQATEDDDGTPFITVTVSGQEQNYQVQYVDSELYHSNSSQTQMTYPFCPVADYQGNGQTYYSTASTGQYAATTQSAGGNTAGNSAHSTTLPYLVPVEEGLLLNGSSQSHSRDSPHSLTVSRERGREWEPPEPTVTTLTNPWATLGLQHEVAYIQEAQSTPQTPTSTTTTNSASGGSLGTGGGGASPDSDQSALGNSNKIASATIKWLSRNYETADGVSLPRSTLYNHYMQHCNEQKLEPVNAASFGKLIRSVFSGLRTRRLGTRGNSKYHYYGIRIKPGSLLNHHSMEDSKSMHGYGPSSGANGVLVSVSSSTSGQMAGSNGSVGMAGSAGQRNGTSKKHSFKPETYEACIQYIGDGSSALPSFPPIELSHSFSSELTLEDVDTFRALYREHCESFLDAVLNLEFGTVEFLLRDFWRSSDNNNLDECEEEKYLSKTKLYLLCHCAEVQKFVREVDYQFYQNTVDVIIPDVLRSIPNALTQAIRNFAKNLELWLCESMMGVPEQLAQIKTSAVSAFCQTLRRYTSLNHLAQAARAVLQNGAQISQMLSDLNRVDFHNVQEQAAWVSQCAPAVVQRLESDFKAALQQQSSLEQWASWLQLVVESAMEEYTGKPTYARAARQFLLKWSFYSSMIIRDLTLRSASSFGSFHLIRLLFDEYMFYLVEHKIAEAQQKTAIAVICERMKKEMDFEFECQFAYITSETEQQNTPSSVSGGDVGNEAKRLKQE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00618897;
90% Identity
iTF_00471350; iTF_00480622; iTF_00473524; iTF_00600799; iTF_00611138; iTF_00514633; iTF_00603092; iTF_00563638; iTF_00484187;
80% Identity
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