Basic Information

Insect: Drosophila tristis
Gene Symbol: Rfx2
Assembly: GCA_018150885.1
Location: JAECWT010000002.1:14255128-14271027[-]

Transcription Factor Domain

TF Family: RFX
Domain: RFX domain
PFAM: PF02257
TF Group: Basic Domians group
Description: RFX is a regulatory factor which binds to the X box of MHC class II genes and is essential for their expression. The DNA-binding domain of RFX is the central domain of the protein and binds ssDNA as either a monomer or homodimer [1]. It recognize X-boxes (DNA of the sequence 5'-GTNRCC(0-3N)RGYAAC-3', where N is any nucleotide, R is a purine and Y is a pyrimidine) using a highly conserved 76-residue DNA-binding domain (DBD) [2].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 5.2e-33 3.9e-29 100.8 0.1 13 78 375 440 371 441 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	5.2e-33	3.9e-29	100.8	0.1	13	78	375	440	371	441	0.95

Sequence Information

Coding Sequence: ATGACCACGCGCCTGGCTCCCCAGCGCCAGTTCATCATCTCGACGCGCTCTGCCGTGGCCAGTGCCAGCGCCAGTGCCGTCGTTGTGGATGCCATCCAAGCGGAGGCAGCGGAGGAGCTGCAGCAGCAGCAGCAGCTGCAGGAGGATGTGCTGACCGTTGAGGTGGAGAACACCAACCACACCGCTGCGACCTCCGTTAGCACATCGCCCACACATGCCGAGCAGTTCGAGTTCTGCACGGAGGATGGTGTCGTTGTCTCCGCCACCCTGGAGGACGTCATGACGCAGAACTGCCAGCTCCTGCAAAAGAAATTAAGCGAAGGCGACGACTCTGTCACGGGCACTGCAAACGGAGCCGAGCAACTGGAGGTGATACGCGTCGTCCTGCCCATGGATGCCAGCGACTCGAGCAACGAGGCCCATACCCACATCCATGGGCATGTGGTCAACAGCAGCAGCGACATCGGCGGCACCATCACCACCACAGAGCCCAATGGCAGCACCATCACCCATTCCATACCCATACACAGCATGGCCGACCTGAGCGCCATCAAGAATGGCGTCGATCTGGCCCAGCAGGTGGCCAATGGCCAGGTGACCGTGGTGCAGGCCACCGAAGACGATGACGGCACGCCATTTATCACCGTTACGGTTTCCGGCCAGGAGCAGAACTACCAGGTGCAATATGTGGACTCGGAGCTCTACCACAGCAACTCCAGCCAGACGCAAATGACATATCCGTTCTGCCCGGTGGGCGATTACCAGGGCAATGGTCAGACATACTACTCGACCACGTCGACGGGCCAGTATGCGGCGACGACGCCGTCGGCTGGGGGCAATGCGGCGGGCAATGCGGCCCACTCCACGACGCTGCCCTACCTGGTGCCCGTGGAGGAGGGCCTGCTGCTGAACGGCTCCTCGCAGTCGCACAGCCGCGACTCGCCGCACAGCCTGACGCACGAGGTTGCCTACATCCAGGAGGCGCAGAGCACGCCCCAGACGCCCACCTCGACGACGACCACCAACTCGGCCAGCGGCGGCAGCCTCGGGACGGGCGGCGGAGGCGCCTCCCCCGATTCGGATCAGAGTGCGCTCGGCAACAGCAACAAGATTGCCTCGGCAACGACGGCCGACGGAGTCAGCCTGCCCAGGTCCACCCTGTACAACCACTACATGCAGCACTGCAACGAGCAGAAGCTGGAGCCCGTGAATGCAGCCAGCTTCGGCAAGCTGATACGCTCCGTGTTCTCCGGCCTGCGCACACGTCGCCTGGGCACGCGCGGCAACTCCAAGTACCACTACTATGGCATCCGCATCAAGCCTGGCTCCCTGCTGAACCATCACTCCATGGAGGACTCCGCCAAGTCGATGCACGGCTACGGGCCATCCGCCGGCAACGGGGCCCTGGTCAGCGTCAGCAGCAGCACGTCCGGCCAGATGGCCGGCTCCAACGGCAGCATGGGCATGTCCGGATCCACCGGCCAGCGGAACGGAACAACCAAGAAGCACAGCTTCAAGCCAGAGACCTACGAGGCATGCATCCAGTACATTGGCGACGGCAGCAGCGCCCTGCCCTCGTTTCCGCCCATCGAGCTGAGCCACAGCTTCAGCACGGAGCTAACGCTGGAGGATGTGGACACATTTCGGGCCCTGTACCGCGAGCACTGCGAGTCCTTCCTGGATGCGGTGCTGAATCTGGAGTTCGGCACCGTGGAGTTCCTGCTGCGCGACTTCTGGCGTTCCAGCGACAACAACAATCTGGAGGAGTGCGAGGAGGAGAAGTACTTGAGCAAGACGAAGCTGTATCTGTTGTGCCACTGCGCAGAAGTGCAAAAGTTCGTACGCGAGGTGGACTATCAGTTCTACCAGAACACAGTGGATGTCATCATTCCGGATGTGCTGCGCTCCATACCGAACGCACTGACCCAGGCCATACGCAATTTCGCCAAGAATCTGGAGCTGTGGCTGTGCGAGAGCATGATGGGTGTGCCGGAGCAGCTGGCCCAGATCAAGACGAGCGCCGTCTCCGCCTTCTGCCAGACACTGCGTCGCTACACCTCGCTCAACCATCTGGCGCAGGCCGCACGAGCCGTGCTCCAGAACGGCGCTCAAATCTCCCAAATGTTGAGCGATCTGAATCGCGTCGATTTTCACAATGTGCAGGAACAAGCCGCCTGGGTGAGTCAGTGTGCTCCGGCTGTGGTGCAGCGATTGGAGAGCGACTTCAAGGCCGCCCTGCAGCAGCAGAGCTCGCTGGAGCAGTGGGCCAGCTGGCTGCAGCTGGTGGTCGAGTCCGCCATGGAGGAGTACACGGGCAAGCCGACATATGCGCGCGCCGCCCGCCAGTTCCTGCTCAAGTGGAGCTTCTACAGCTCGATGATCATACGGGACTTGACGCTGCGCTCGGCCTCGAGCTTCGGCAGCTTCCACCTGATCAGACTGCTGTTCGACGAGTACATGTTCTATCTGGTGGAGCACAAGATAGCCGAGGCGCAGCAGAAGACGGCCATAGCGGTCATATGCGAGCGCATGAAGAAAGAGATGGACTTTGAATTCGAGTGCCAGTTTGCGTACATTACCAGCGAAACGGAGCAGCAGAACACCCCCAGCTCGGTCAGTGGCGGGGCGGATGTGGGCAACGAGGCGAAGCGACTGAAGCAGGAATGA
Protein Sequence: MTTRLAPQRQFIISTRSAVASASASAVVVDAIQAEAAEELQQQQQLQEDVLTVEVENTNHTAATSVSTSPTHAEQFEFCTEDGVVVSATLEDVMTQNCQLLQKKLSEGDDSVTGTANGAEQLEVIRVVLPMDASDSSNEAHTHIHGHVVNSSSDIGGTITTTEPNGSTITHSIPIHSMADLSAIKNGVDLAQQVANGQVTVVQATEDDDGTPFITVTVSGQEQNYQVQYVDSELYHSNSSQTQMTYPFCPVGDYQGNGQTYYSTTSTGQYAATTPSAGGNAAGNAAHSTTLPYLVPVEEGLLLNGSSQSHSRDSPHSLTHEVAYIQEAQSTPQTPTSTTTTNSASGGSLGTGGGGASPDSDQSALGNSNKIASATTADGVSLPRSTLYNHYMQHCNEQKLEPVNAASFGKLIRSVFSGLRTRRLGTRGNSKYHYYGIRIKPGSLLNHHSMEDSAKSMHGYGPSAGNGALVSVSSSTSGQMAGSNGSMGMSGSTGQRNGTTKKHSFKPETYEACIQYIGDGSSALPSFPPIELSHSFSTELTLEDVDTFRALYREHCESFLDAVLNLEFGTVEFLLRDFWRSSDNNNLEECEEEKYLSKTKLYLLCHCAEVQKFVREVDYQFYQNTVDVIIPDVLRSIPNALTQAIRNFAKNLELWLCESMMGVPEQLAQIKTSAVSAFCQTLRRYTSLNHLAQAARAVLQNGAQISQMLSDLNRVDFHNVQEQAAWVSQCAPAVVQRLESDFKAALQQQSSLEQWASWLQLVVESAMEEYTGKPTYARAARQFLLKWSFYSSMIIRDLTLRSASSFGSFHLIRLLFDEYMFYLVEHKIAEAQQKTAIAVICERMKKEMDFEFECQFAYITSETEQQNTPSSVSGGADVGNEAKRLKQE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00618897;
90% Identity: iTF_00574552;
80% Identity: -