Dsub002534.1
Basic Information
- Insect
- Drosophila suboccidentalis
- Gene Symbol
- -
- Assembly
- GCA_037043435.1
- Location
- JBAMBK010000280.1:1031534-1036740[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 0.00075 0.054 14.2 0.3 1 23 143 165 143 165 0.98 2 14 0.00016 0.011 16.4 1.3 1 23 397 419 397 419 0.98 3 14 2.9 2.1e+02 2.9 0.5 1 23 425 448 425 448 0.91 4 14 0.53 39 5.2 0.7 1 23 473 496 473 496 0.92 5 14 0.0014 0.099 13.4 1.9 3 23 775 795 774 795 0.92 6 14 0.055 4 8.3 1.4 1 23 801 824 801 824 0.98 7 14 0.38 28 5.7 1.5 2 23 861 882 860 883 0.92 8 14 0.0048 0.35 11.7 0.8 1 23 904 927 904 927 0.97 9 14 0.026 1.9 9.4 0.3 1 20 1131 1150 1131 1154 0.89 10 14 0.0037 0.27 12.0 3.4 1 23 1167 1189 1167 1189 0.98 11 14 0.00042 0.031 15.0 0.3 2 23 1195 1217 1194 1217 0.95 12 14 0.0023 0.17 12.7 3.5 3 23 1250 1273 1249 1273 0.86 13 14 1.7 1.2e+02 3.7 2.0 1 23 1278 1300 1278 1300 0.94 14 14 0.0032 0.23 12.2 1.0 1 23 1306 1329 1306 1329 0.96
Sequence Information
- Coding Sequence
- ATGGCGAGAAAGCGAGTGAAAACAGAGGACATGGAAGTGAATTACAAGTTTTCATGTCGCTGTTGCCTGAAGTCCGAGGCGGAATTCTTCAAGTTGGACTCCTTGACAGAGACTGTAATAGGCGACAATGATGAGTCCTCAACGAAAATACCCCTTATACGTTTACTATTATTCTGTATGCGTACTGAAAACCTGCCCGAGCTGCCGCAATACATTTGCGTGGAGTGCAGCAAGAGCTTGCAAATCGCATACATTTTCATCCAAAACGGTCTCAGGGCACATGAGATACTGTGTCGCAAACTATGCCctggaaaactgaaaactactCGGCGCTTCaatggacaacaacaacaactcttcGAGGATAACCGAGATGACGCGACAATCGGCACGCTGAAGGCGAAGCCTCCTAAAACCGCCCTGCGCCACGAATGCAAAGTATGTGGCGCCATTATCTATAATCGAGTGGAACTCAAGCAACATATTCGCATGCACACAGAGGAATCGAAACATGCGTGCAAGCTATGCAAGTTTGTGACGCTTAAACAGCGTCTACTGCCAGAACATTATCGAAGAGACCACGGCTTGACGGCTGTCCAAATTGATCAGCAACTTAAACTGAGAAGATCTATGCaggcggcagctgctgcaaccAAACTGACGACGacttcaacagcagcagcagcaacaactgtggATGTTAATCAGGTGAAGGTGTGCACACTGGAGGACATGGAGCTGCTGATACCCACTGTTCTTAGGCCGGAGGACTTTTCGCAACCACAACTGGATTCAGACCAACTGCGTGATATTGAACAACAGTTGACAAACTCCTTGGCTGTTGGCCAATCTGACTCGGGCTTAAGCTCCGTTGTCATGCCAACCGAGCCAACGATAGCGTCGGGTGAAAGTGGCAATGTGAGCATAGGTGCACAGTTTCTGGTCATGCCAGATGGCTCGTTGCAGCAAGTCGATGATGGCGGAGTTGTTTTCGAGTACATCGATGACAGCAAGAGACCGACAACGACCACCAATACAACACTGCAGAACTTATTGGATGACTCCAAGCCAGAAGTGTCTTATAATGCAATGGATATCGATGTAAACCACTTGGTGACGGATCGGCTGCCACAGATAACAGTGAAACCACCCACTAGACCAGGTCCTGGATCGAATGCCGCCCTGAAACACAAATGTAAACTGTGTCCCAAAGCATTTCCCACGGTGGCGCGTCTTAAATCTCATCAGTTGACACACAGTCATTTGCCGAAGTTCTATTGTGATCAGTGCTCCTACTACTCGCTACGCAGCGCTGATCTCATCCAACATTACATGGAGGATCACAATACTTCGATTGGTGAAAGTAAAAGTCAACTCGAAAAATCATCGTTGTCGACGACAGACAGGAGCTGTACATATTCCTGCGACTTGTGCTTGTTTGACACACCGAGCAGTGTTCAGCTTCGAAAACACTACAGCGATAAGCATCTGATGCAGCCCAGTGAGGTACAGTTGCGTCCCAGCTGGAACCATGAGTCCAAGGAGAAGGGCGGCCGTGCGACGCTGGTCAGTGACCAGAATCAGCTGAGGAATTCACATCCAGCCATATCACATATTCCGCTGGGTATTAAATATTCAACAGCTTCGGCTGTGGCCACAGCCGAATTGAGAGCGACAAACGAGTCGAATGCAACGACAGCAATGcatctgcaacaacaacaagcacagccaacaacaacagctgtggTGACGCCTACTGGTGACATAAATGTGGTTGTGGATGCCACCACGATGTTCtatgcagcaacagcagcttcaACAAGTGAAgaagcaacaacgacaacaacagcaacaattgcaacggAATCAAACGAATTTACAATGTTCCCAGAGCAATCTTTTGCCAACACCATGACAACCACAACTTTGACGAGAGAGGCAGTAAACTCTGCGGCTGTTGCAACCACAGGAAATCCCAACTGTAGCATCTTTGGTGATATGCAGGATTTCATTGATGACACCGATGTGGCAGCTGTATGCACCATACCCGCCGACGATATGCCTGTCGTCGATGGCGATGACATTGTTATTGATAACAATAATATGAGTCTCGACTTTGATGCCGAGAATCTATTCGAAGACTTTGAAGAGGACGTTGAGGTTGGCgaagatgacgatgacgaggatgaggaggaTGCTGAGAATGATGATGAGAATGACAATAATGATGCGGCTGCCGACCAAAATTTGTTGCTGACcagcgatgatgatgacgtcgACGACTTTGATGACGAGCAATCGAAGCATCTGCAGAAGCCATATTGCATCTATTGTAACAAGAAGTTTACCAGCCAATACAAATTCGAGAACCATATGTTTGTGCATCGCGGTTTGGCACCGTATCGCTGTGAGCTATGCACGAATCTGTACAATATGAAGCGTTTGCTGATACGACACTACAAAACGGTGCACAAGCGAATGCCCACTAGGGACATGGTGCAGGCCAAGGGCGACAAGATATTAGTGGAACGCACTGCCATCGAAAAGCTGAACACCAATGCTGAGAAGCCTCCCATGCTGATGTGTGCCAAGTGTCCGTTTGAATGCGAACAGGAGGCCGAGATGCGAAAGCATCTGAATGCGCATCATGGCATCAACGATGGCGTCTCTGTTCATGCAAACGAGGTGTTTATCATACGCAAACTGCCTTTTGAGTGTCCACGCTGCATTCGCTCATTTGCGGCCAAGCGCACGCTGACTCGCCACCTGCAACGGAGCCATTTAGTGGACACAATCATTGAGATGCAGGCGCCTCAATTGACAACTAGTtcggcggcaacaacaaccacatcgACGGCCACAACCACATTGCCGAAGAATGACAGCGATGGCTGTGGTGACAATAAAGCAATCTTCATGGATAATTTGAGGCAGCGTGACTTTGGCAATGCTGATGgcgatggcaatggcaatggaaaaTGCGAAGACAGAGCCTTAAACAGTGACACAGGAATAGAAACGGATAATGAAGATATAGACACAAAACCATCAACAGCAAGGTCAGGAATAAACGAAAATGTAAAGCAGACAAATACAGACAAAGAAGCGTCCCCAGAGGTTACAGCTTCTACGACAAGGTTACCGTTGACAACATCAGCtcaaacaccaacaacaacaacaacagtgaacTCTACACTGTttccaacgccaacgccattTGATTTTGACCTGGATTTCATTGGCAATGGATCACTAAAGAACAGCAACGAAAGCTTTAACATTATGTCAAGCAGCCGTCAACTGTTAAACGGAAGCGACAAACTACTGACAGCTGCGTTGGAGCCATCGCCAGTTAAGGATATGCGTCCGAGATTGCCCCGCACTCCCATTTATGTGTGCAAGCAGTGTAACCAAACATTTGACGAGTTGGGCAAACTGTTGCAGCACGAAGTGGAGCAGCATTCAAACGGGACTGCGTCGCTGCGCAGAAACTATCAACATCAGTGCAACATTTGTAGCAGCTCATACCGAACGGTGACACTACTTAACTATCACATGAAAAGACATGCACCGAAAAATGTTCAGTGTAAACAGTGCACCAAAGAGTTTACGTCCAATTCGGAGATGGAGGAGCACGTGGAGTCGGAGCATGTGGTGTCGGAATACGTGGACTCGGAACATGTACAGTCGGAGCACGTAGAGACGGCGCATGTAGTGTCGGAGCAGGGCAAAAAAGTGCCCATGATATGCGGAATGGATGGCTGCACTAAGACATTCAATTACAAGCATCATCTGAAACGCCATCAGACAGCTTCCCATACGCCCGTTCGCTATATATGTCGCCAGTGCGGACGCGATATGTTGACCAGTCTCAACCTAAGGCATCACATGTATAGCCACAAGAGCTCACATTCATACAAGTGTCCCAAATGTGTGCGCACTTATATAAGAGGCAATAGCTTTAAAAGGCACGCTCTGCGTGAACACAAATGGAATCCAACTGATGGTGAGATGGCCAAAATATATTGCCTGAATGAAACTCCGCCCTCGATGCAATACGGGATACGGGAACTAAGATCGGTGAATGCGGATAATGAGCATTCGGATTAG
- Protein Sequence
- MARKRVKTEDMEVNYKFSCRCCLKSEAEFFKLDSLTETVIGDNDESSTKIPLIRLLLFCMRTENLPELPQYICVECSKSLQIAYIFIQNGLRAHEILCRKLCPGKLKTTRRFNGQQQQLFEDNRDDATIGTLKAKPPKTALRHECKVCGAIIYNRVELKQHIRMHTEESKHACKLCKFVTLKQRLLPEHYRRDHGLTAVQIDQQLKLRRSMQAAAAATKLTTTSTAAAATTVDVNQVKVCTLEDMELLIPTVLRPEDFSQPQLDSDQLRDIEQQLTNSLAVGQSDSGLSSVVMPTEPTIASGESGNVSIGAQFLVMPDGSLQQVDDGGVVFEYIDDSKRPTTTTNTTLQNLLDDSKPEVSYNAMDIDVNHLVTDRLPQITVKPPTRPGPGSNAALKHKCKLCPKAFPTVARLKSHQLTHSHLPKFYCDQCSYYSLRSADLIQHYMEDHNTSIGESKSQLEKSSLSTTDRSCTYSCDLCLFDTPSSVQLRKHYSDKHLMQPSEVQLRPSWNHESKEKGGRATLVSDQNQLRNSHPAISHIPLGIKYSTASAVATAELRATNESNATTAMHLQQQQAQPTTTAVVTPTGDINVVVDATTMFYAATAASTSEEATTTTTATIATESNEFTMFPEQSFANTMTTTTLTREAVNSAAVATTGNPNCSIFGDMQDFIDDTDVAAVCTIPADDMPVVDGDDIVIDNNNMSLDFDAENLFEDFEEDVEVGEDDDDEDEEDAENDDENDNNDAAADQNLLLTSDDDDVDDFDDEQSKHLQKPYCIYCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKILVERTAIEKLNTNAEKPPMLMCAKCPFECEQEAEMRKHLNAHHGINDGVSVHANEVFIIRKLPFECPRCIRSFAAKRTLTRHLQRSHLVDTIIEMQAPQLTTSSAATTTTSTATTTLPKNDSDGCGDNKAIFMDNLRQRDFGNADGDGNGNGKCEDRALNSDTGIETDNEDIDTKPSTARSGINENVKQTNTDKEASPEVTASTTRLPLTTSAQTPTTTTTVNSTLFPTPTPFDFDLDFIGNGSLKNSNESFNIMSSSRQLLNGSDKLLTAALEPSPVKDMRPRLPRTPIYVCKQCNQTFDELGKLLQHEVEQHSNGTASLRRNYQHQCNICSSSYRTVTLLNYHMKRHAPKNVQCKQCTKEFTSNSEMEEHVESEHVVSEYVDSEHVQSEHVETAHVVSEQGKKVPMICGMDGCTKTFNYKHHLKRHQTASHTPVRYICRQCGRDMLTSLNLRHHMYSHKSSHSYKCPKCVRTYIRGNSFKRHALREHKWNPTDGEMAKIYCLNETPPSMQYGIRELRSVNADNEHSD
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00534121; iTF_00529071; iTF_00575887; iTF_00523223; iTF_00585496; iTF_00586234; iTF_00507135;
- 90% Identity
- -
- 80% Identity
- -