Dfal001526.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila falleni
Gene Symbol
-
Assembly
GCA_035045575.1
Location
JAWNOV010000011.1:9511851-9516881[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.0014 0.11 13.2 0.4 1 23 144 166 144 166 0.97
2 13 0.00014 0.011 16.3 1.3 1 23 394 416 394 416 0.98
3 13 0.083 6.2 7.6 1.3 1 23 471 494 471 494 0.92
4 13 0.0013 0.095 13.3 1.9 3 23 786 806 785 806 0.92
5 13 0.051 3.8 8.3 1.4 1 23 812 835 812 835 0.98
6 13 0.35 26 5.7 1.5 2 23 872 893 871 894 0.92
7 13 0.0045 0.33 11.6 0.8 1 23 915 938 915 938 0.97
8 13 0.015 1.1 9.9 0.4 1 23 1154 1177 1154 1177 0.90
9 13 0.0034 0.26 12.0 3.4 1 23 1190 1212 1190 1212 0.98
10 13 0.00028 0.021 15.4 0.1 2 23 1218 1240 1217 1240 0.95
11 13 0.0011 0.079 13.6 2.7 3 23 1284 1307 1282 1307 0.87
12 13 0.1 7.6 7.4 2.5 1 23 1312 1334 1312 1334 0.97
13 13 0.0021 0.16 12.7 1.0 1 23 1340 1363 1340 1363 0.97

Sequence Information

Coding Sequence
ATGGCGCGAAAACGAGTTAAAACGGATGACATGGAAGTGAATTACAAATTTACGTGCCGCTGTTGCCTGAAGTCCGAGGCGGAATTCTTCAAGCTGGACTCCCTAACAGATAGTATCATAGGCGATAATGATGAGTGCTCCACAAAAATACCCCTTATACGTTTACTACTATTCTGTATGCGCACGGAAAACTTACCCGAGCTGCCGCAATACATTTGCGTGGAATGCAGCAAGAGCTTGCAAATTTCCTACTTCTTTATCCAAAACAGTCTTCGGGCACATGAAATTCTGTGTCGCAAACTATGCCCgggaaaactgaaaacaacaTCCCGTTTCAATGGCCAACAAATCGGCGAGCAGGAGCGACAAGATGACGCGACAGTCGTCATACAGAAGGCGAAGACGAAGCCTCCCAAGTCCGGATTGCGCCACGAATGCAAAGTATGTGGCGCCATTATCTTTAATCGAGTGGAACTTAAGCAGCACATTCGCATGCACACAGAATCAGGACACGCGTGCAAGCTATGCAAATTTGTGACTTTTAAACAGCGTCAACTACCAGAGCATTATCAAAACGTGCATGGATTGACGGCTGCCCAAATTGAACAGCAACTTAAGATCAGAAGATCGATGCaggcggctgctgctgcaacaacaacagctgcgaCAACCACATCCACTGTGGATGATAATCAGGTGAAGGTGTGCACACTGGAGGACATGGAGCTGCTGATACCCACTGTGATGAGGCCGGAGGACTTTTCGCAGCCACAACTGGATGCAGATCAACTGCGTGATATTGAGCAGCAATTGTCCAACTCGTTGGCTGCTGGCCAATCTGGGTCTGGGACAGTTGTCATGCCAACGGAGCCGACGATAGCAACGTGTGACAGTGGCAGTGCCAACATGAGCATAGGAGCACAGTTTCTGGTCATGCCCGATGGCTCGTTGCAGCAAGTCAATGATGGCGGAGTTGTTTTCGAGTATATTGATGACAGCAAAAGTGCCAGCACCCCCAAAACAACCCTACAGAGCTTATTGGATGACTCCAAACCCGACGTGGACGTGTCTTACAATGCAATGGACATTGATGTGGACCACTTGGTGGCGAATGCGCTGCCACAGATCACAGTAAAACCACCGCCAAGACCAGGTCCTGGATCAATTGCCGCCCTGAAACACAAGTGTAAACTGTGTCCCAAAGCCTTTCCCACAGTAGCGCGTCTTAAATCTCATCAGTTAACACACAGTCatttacCAAAATTCTATTGTGATCAGTGTGCCTACTATTCGCTACGCAGCGCCGATCTTATCCAACATTATATGGAGGAGCACAAGACTTTCATTGGTGATAACAAGAGTCAACTGCAGAAATCGTCGCTGTCGTTGACGACAGACAGAAGTCGCATATATTCCTGCGACATGTGCTTATATGAGACACCGACCAGTTTCCAGCTACGAAAACACTACAGCGACAAGCACCTGATGAAGCCCAGTGAGGTGCAGTTGCGTCCCAGCTGGAGCAATGAGTCCAAGGAGAAGCTCGGCAGATCGACGCTAGTCAGTGACCAAAATCAGCTGAGGAACTCACAACCAGCCATATCACATATTCCGCTGGGTATTAAATATCCAACAACGTCGGCTGTGACAACAGCTGAATTGCGAGCGACAAACGAGTCGAGTGCAACCACAGCAATGCAACTAAATCCAgcacagccaacaacaacaacaacagctgtggTCACGCCTGCTGGTGACATAAATGTGGTCGTAGATGCAACCACGTTGTTCTatgcagcaactgcagcctCAGAcactgtggcagcaacagcgacgacgacaacaacagcgccAATTACAACAGCATCAAACGAGTTTACAATATTTCCAGCGCAATCTTTTGCCAACagcatgacaacaacaacaacgatgaccGGAGAGACAAGCGGATTGCTGCCTGCTGTTaatactgttactgttgctgctgttgctcccaCAGGAAATCCAAACTCTAGCATATTTGGGGATATGCAGGACTTTATTGATGACACTGATGTGGCAGCTGTATGCACTATACCCGCCGACGATATGCCAGTCGTCGATGGCGATGACATTGTTATTGATAACAATAATATGAGCCTCGATTTTGATGCTGAGAATCTATTCGAAGACTTTGAGGAAGACGCTGAAGTTGGCgaggatgatgacgacgacgacgatgaggaGGACGCTGAGAATGATGATGAGAATGATAACAATAATGCGGCTGCTGATCAAAATTTGTTTCTCAccagcgatgatgatgatgttgatgactTTGATGACGAACAATCGAAGCATCTGCAAAAACCATATTGCATCTATTGTAACAAAAAGTTTACCAGTCAATATAAGTTCGAGAATCATATGTTCGTACATCGCGGGTTGGCACCATATCGCTGTGAGCTCTGCACGAATCTGTACAATATGAAACGTCTACTTATACGGCACTACAAAACGGTGCACAAGCGTATGCCCACTCGGGACATGGTTCAGGCCAAGGGCGACAAGGTGTTAGTGGAGCGTACAGCCATTGAAAAGCTGAACATCAATGTGGAGAAGCCTCCCATGCTGATGTGTGCCAAGTGTCCTTTTGAATGCGAACAGGAAGCTGAGATGCGGAAGCATCTAAATGCGCATCATGGCATCAACGATGGCGTCTCTGTGCATGCCAACGAGGTGTTTATCATTCGCAAATTGCCTTTTGAGTGTCCACGTTGCATTCGCTCATTTGCGGCCAAGCGAACGCTGACTCGTCATTTGCAACGGAGCCATTTGGTGGACACAATCATTGAGATGCAGGCGCCTCAATTGACAACCAGCtcggcgacaacaacaaccacagcaacgtCTACAACAACACTGCCAAAGAATGACAACGATGTCTGCGGTGACaataagacaacaacaatgcagcaGGAGTCCAACTTCATGGATACTTTGGCGGCTGACGGCGATGGCAATGAAAAATGCGAAGACAGTATGATAAACAGTGACACAGGAATAGAAACGGATAATGAAGATATATGCACAAAaccattaacaacaacaacaacaacgtcagcaATAGGGACAGTAAAAACAGCTTTAAACGAGGACAATGCAACTGAAACAAACACAGAAGAGAAAGTTGTATCTTCAACAAGGTCAGCATCATCGACACCTCTAACAACATCAGAAACAGCagataaaacaacaacagtggaCTCAACACCCTTTCCACCACCTACGCcctttgattttgatttagaTTTCATTGGCAATGAATCCCATGCCACTTCGCTtaagaacaacaacgataGCTTTAGCATTGTATCAAGCGTCCGTCAACTTTTAAATGGCAGCGACAAACTGCTGACAGCTGCATTGGAGCCATCGCCTGTTAAAGACCTACGTCCGAGGTTGCCCCGTACTCCCATTTATGTGTGCAAGCAGTGTAACCAGACATTCGACGAGTTGGGCAAACTGTTGCAGCACGAATTGGATCAACACTCAAGCGGGACTGTGTCGCCGCGCAGAATCTATCAACATCAATGCAACATATGCAGCAGCTCATATCGCACGGTGACGCTGCTGAATTATCACATGAAAAGGCATGCACCTCGTAAAGTTCAGTGTGAACAGTGCCCCAAGGAGTTTACGTCCAATTCGGAGATGGAGGAACATGTGGAATCGGAGCATGTTGAGACAAAACAAGTAAAGTCGGAGGAGCATTTGGAGTCGAAACAAGTTAAATTGGAACATGTAAAGTCGGAGCAGTTAGAGTTGGATAATGTGAAATCGGAGCATGGCAAACAAAAGGCCTTGATATGCGGAGTCGATGGTTGCACCAAGACATTCAATTACAAACATCATTTGAAGCGTCATCAGACAGCTTCCCATACTCCCGTTCAGTATATATGTCCAAAGTGTGGACGCGATATGTTGACCAGTCTCAACCTGAGGCATCACATGTGTATCCACAAGagcacacactcatacaagTGTCCCAAGTGTGTGCGGACTTATATACGAGGCAATAGTTTTCGAAGACACGCTATGCGTGAACACAAATGGGATCCGACTGATGCCGAAATGGCCAACATATATTGCGTTAATGAAACACCACCGTCGATGCAATATGCAATACGGGAACTAAGATCGGTGAATGTTGAAAATGAGCTGTCGGATTAG
Protein Sequence
MARKRVKTDDMEVNYKFTCRCCLKSEAEFFKLDSLTDSIIGDNDECSTKIPLIRLLLFCMRTENLPELPQYICVECSKSLQISYFFIQNSLRAHEILCRKLCPGKLKTTSRFNGQQIGEQERQDDATVVIQKAKTKPPKSGLRHECKVCGAIIFNRVELKQHIRMHTESGHACKLCKFVTFKQRQLPEHYQNVHGLTAAQIEQQLKIRRSMQAAAAATTTAATTTSTVDDNQVKVCTLEDMELLIPTVMRPEDFSQPQLDADQLRDIEQQLSNSLAAGQSGSGTVVMPTEPTIATCDSGSANMSIGAQFLVMPDGSLQQVNDGGVVFEYIDDSKSASTPKTTLQSLLDDSKPDVDVSYNAMDIDVDHLVANALPQITVKPPPRPGPGSIAALKHKCKLCPKAFPTVARLKSHQLTHSHLPKFYCDQCAYYSLRSADLIQHYMEEHKTFIGDNKSQLQKSSLSLTTDRSRIYSCDMCLYETPTSFQLRKHYSDKHLMKPSEVQLRPSWSNESKEKLGRSTLVSDQNQLRNSQPAISHIPLGIKYPTTSAVTTAELRATNESSATTAMQLNPAQPTTTTTAVVTPAGDINVVVDATTLFYAATAASDTVAATATTTTTAPITTASNEFTIFPAQSFANSMTTTTTMTGETSGLLPAVNTVTVAAVAPTGNPNSSIFGDMQDFIDDTDVAAVCTIPADDMPVVDGDDIVIDNNNMSLDFDAENLFEDFEEDAEVGEDDDDDDDEEDAENDDENDNNNAAADQNLFLTSDDDDVDDFDDEQSKHLQKPYCIYCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKVLVERTAIEKLNINVEKPPMLMCAKCPFECEQEAEMRKHLNAHHGINDGVSVHANEVFIIRKLPFECPRCIRSFAAKRTLTRHLQRSHLVDTIIEMQAPQLTTSSATTTTTATSTTTLPKNDNDVCGDNKTTTMQQESNFMDTLAADGDGNEKCEDSMINSDTGIETDNEDICTKPLTTTTTTSAIGTVKTALNEDNATETNTEEKVVSSTRSASSTPLTTSETADKTTTVDSTPFPPPTPFDFDLDFIGNESHATSLKNNNDSFSIVSSVRQLLNGSDKLLTAALEPSPVKDLRPRLPRTPIYVCKQCNQTFDELGKLLQHELDQHSSGTVSPRRIYQHQCNICSSSYRTVTLLNYHMKRHAPRKVQCEQCPKEFTSNSEMEEHVESEHVETKQVKSEEHLESKQVKLEHVKSEQLELDNVKSEHGKQKALICGVDGCTKTFNYKHHLKRHQTASHTPVQYICPKCGRDMLTSLNLRHHMCIHKSTHSYKCPKCVRTYIRGNSFRRHAMREHKWDPTDAEMANIYCVNETPPSMQYAIRELRSVNVENELSD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00602106;
90% Identity
iTF_00523223;
80% Identity
-