Basic Information

Insect: Drosophila santomea
Gene Symbol: -
Assembly: GCA_016746245.1
Location: NC:25383979-25388886[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 25 0.00084 0.053 13.6 0.8 1 23 207 229 207 229 0.96

2 25 1.2 79 3.6 2.9 1 19 235 253 235 257 0.80

3 25 0.0018 0.12 12.5 0.2 2 23 289 310 288 310 0.97

4 25 0.0061 0.39 10.9 4.4 1 23 383 406 383 406 0.94

5 25 0.72 46 4.4 4.0 1 23 446 468 446 469 0.95

6 25 0.0013 0.082 13.0 0.3 2 23 479 500 478 500 0.96

7 25 0.74 47 4.4 0.2 1 23 577 600 577 600 0.93

8 25 0.011 0.71 10.1 3.0 2 21 610 629 609 630 0.93

9 25 2.3 1.5e+02 2.8 2.9 1 23 639 661 639 662 0.91

10 25 0.0063 0.4 10.9 2.2 2 23 676 697 675 697 0.97

11 25 0.00022 0.014 15.5 7.1 1 23 705 727 705 727 0.97

12 25 0.0025 0.16 12.1 0.6 1 23 865 888 865 888 0.95

13 25 0.064 4.1 7.7 2.5 2 23 896 919 895 919 0.91

14 25 0.0047 0.3 11.3 1.0 1 23 925 948 925 948 0.97

15 25 4.9e-05 0.0031 17.5 1.9 2 23 967 988 966 988 0.97

16 25 0.00017 0.011 15.8 1.0 1 23 995 1017 995 1017 0.98

17 25 0.06 3.8 7.8 0.0 2 21 1044 1063 1043 1064 0.92

18 25 0.77 49 4.3 3.6 1 23 1114 1137 1114 1137 0.95

19 25 0.0039 0.25 11.5 0.9 1 23 1174 1197 1174 1197 0.95

20 25 0.0013 0.084 13.0 2.5 1 23 1223 1246 1223 1246 0.98

21 25 4.6e-06 0.00029 20.7 0.2 2 23 1271 1292 1270 1292 0.95

22 25 0.0002 0.013 15.6 3.5 1 23 1298 1320 1298 1320 0.99

23 25 1.8e-06 0.00011 22.0 2.0 1 23 1326 1348 1326 1348 0.97

24 25 1.6e-07 1e-05 25.3 2.4 1 23 1354 1376 1354 1376 0.99

25 25 0.00081 0.052 13.7 0.2 1 22 1382 1403 1382 1406 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	25	0.00084	0.053	13.6	0.8	1	23	207	229	207	229	0.96
2	25	1.2	79	3.6	2.9	1	19	235	253	235	257	0.80
3	25	0.0018	0.12	12.5	0.2	2	23	289	310	288	310	0.97
4	25	0.0061	0.39	10.9	4.4	1	23	383	406	383	406	0.94
5	25	0.72	46	4.4	4.0	1	23	446	468	446	469	0.95
6	25	0.0013	0.082	13.0	0.3	2	23	479	500	478	500	0.96
7	25	0.74	47	4.4	0.2	1	23	577	600	577	600	0.93
8	25	0.011	0.71	10.1	3.0	2	21	610	629	609	630	0.93
9	25	2.3	1.5e+02	2.8	2.9	1	23	639	661	639	662	0.91
10	25	0.0063	0.4	10.9	2.2	2	23	676	697	675	697	0.97
11	25	0.00022	0.014	15.5	7.1	1	23	705	727	705	727	0.97
12	25	0.0025	0.16	12.1	0.6	1	23	865	888	865	888	0.95
13	25	0.064	4.1	7.7	2.5	2	23	896	919	895	919	0.91
14	25	0.0047	0.3	11.3	1.0	1	23	925	948	925	948	0.97
15	25	4.9e-05	0.0031	17.5	1.9	2	23	967	988	966	988	0.97
16	25	0.00017	0.011	15.8	1.0	1	23	995	1017	995	1017	0.98
17	25	0.06	3.8	7.8	0.0	2	21	1044	1063	1043	1064	0.92
18	25	0.77	49	4.3	3.6	1	23	1114	1137	1114	1137	0.95
19	25	0.0039	0.25	11.5	0.9	1	23	1174	1197	1174	1197	0.95
20	25	0.0013	0.084	13.0	2.5	1	23	1223	1246	1223	1246	0.98
21	25	4.6e-06	0.00029	20.7	0.2	2	23	1271	1292	1270	1292	0.95
22	25	0.0002	0.013	15.6	3.5	1	23	1298	1320	1298	1320	0.99
23	25	1.8e-06	0.00011	22.0	2.0	1	23	1326	1348	1326	1348	0.97
24	25	1.6e-07	1e-05	25.3	2.4	1	23	1354	1376	1354	1376	0.99
25	25	0.00081	0.052	13.7	0.2	1	22	1382	1403	1382	1406	0.91

Sequence Information

Coding Sequence: ATGCTTCCGTCGGATATTTGCCGCACTTGTGCGGTGCAGAACAACCAATTGCTGCCCTTGTCCACTCGCCTGGACAGAGACGCCTCCAAAAGCTACTATGCGGTGCTCCAGGAACTGACGCAAATCGATCTGGAGAGCTCCGATGACAACCTGCCGCAACATCTATGCCCCGAGTGCTGGACGCGAATGGAAGGTGCCTACGCCTTTGTGCAGCAGGCCAAAAAAGTCAATGGAGAGCTGTTGGCGCGGCTGAGGGAATGTCTGGATGAAATGCCCATTGATATTCCCGCGGAGCAGAACATTAAAACGGAAGTGGACCTCGATGATGGCGGCAACAAGCCCGGAGTCGAGGTGGACGCCACCGAAACGGCGGCTTTGGAGCTGAAGTGGCAACCGGAGAGTGACAGCGATCAGGAATTTGGTGCTGCGCCGGAAAGTGATGAAGATCAAGTGGGAAAGAAGTCCTATCATCTGCGTCGAAGCTCCCGAAAAGTAAAGCAGCCAGTGGAAAGCGAAAATGAGGAATGTAAGCCATCTGAAGAACCATCGCCCGTTAAGCGCCGTCGAGGACGTCCACCTGGTCCAGCGAAAAGCCAGGCGATGACCACTGATGGCCGCCACGCATGTGAGGTGTGCGGAAAGACATTCTCCTGGTACCGCGACATGCAGCGCCACGCCAGGATCCACTTCGATAACGCTTCCTACGTGTGCGATACCTGTGGCAAGGGATTTCTGCGCAAGGACAAGTATATATTCCATTTACGATGCCACAAGAAGCGGGAGGCGAAATGGAAGGCTCTCCAACTCGGAAAAGAGTGGCGTTTTGCTGAGCGTCTCTACAGCTCAGGAAGGTTGAAAAGAGTCGAGTGTAAGCTATGCGGGTCGATTTTCCAACAAATGGAGGAGCTTAGAATTCACCTAAGGAGTCATGCAGATGTGGAGACCTTAGCCAACTTAAGAAGGGATAGTGACGTTGTAAGGGAGCATTTTCCTGGCTTGCCTTGTGACTTGGACAATATTAGGCAACAGATCTGCGGTGACATAGCAGAAGGCCATTTGGAGAAGTATGCATGTGTTGTGAATTTCCACGGATACGAGCTGGGACTCAGTGATTCCGATGAGGACTGTGACAGCAAAGAGTCTAAATACCATTGCTTGGTGTGCAATATGTCTTTCAATCGCAAACATCGTCTGATGAGACACACCCTGGAGGACCACTCCCAATCTGCGACAACGCTTCCCTGGCAGCGCTGCAGTTCCTGCAAAGTTGGTTTCCTATGCCTAACGATCTACAACAAACATTTGAACACGCATTGCCTCAGCAAAATACGTAGATATCGCTGTCGTAAATGTTCCGGGAGGTTTATGTGGCCGGAAAACCTTCAAAGACACGCGTGCTCGCACCACGAGGAGAAAACGATTGCCAGCCAAATAATGTGCTCCTTGTGCGAAACCTCGCTAACTAGCTTATCGCAACTTCGCCTTCACCTACTCACACACCAACATGATTTGAATGGCATTAATCCGGCGTACAATTCCATGTTCTTTCGGTCGTTTTATCCTGACGGTTTGAAGTGCACTATCTCGGATCTTGCCGTGCGTATAGCTGAGGACTTCGAGGTTCAAGACTTTGATCGCTATTATAACGCCAGCACCGAAAGTGGACAGGAGCTCGATCTTTTTGAATCCGAGTCAGAGTTGAGCGACGTGGAGACTTCAAAACCATCGCACATCTGTCTTTTATGTGGAGAAGTTTCGAGTTCCCTGAAGATCCTGATGCAGCACCAAATAAGCGCACATTCCGATGGGGTGACTGAGCTTCCTTGTCACTGCGAGTACTGTGGATCTGGCTTCGTAAGCAAAGCCCTTCTTCAACAACACCGTAGGCACCGCTGCGAAAAGAAACACTCCCGATTTCACTGCCGAGTATGCAATATCTGGTTCATATGGGAGTCGAACTATGAGAAACACCAACTGACTCACCATAACAAAACGAAAGATGGAGAAGAAGAACCCACAAAGTTGAAGTGCGACCAGTGCGAAAAGGTATTCATCTGGCACAAAGATCTTAATCGTCACAAACGTCTGCATCAACCTCAGTCGGCTGCCCAGTTCGACTGTCCCCATTGCCATCGTAGATTCCACCGCAAGGATGGCTTAAAGTCCCACCTAAAAGTTCACGCCGGAAATTCAGATTACGTAAATAATCAGCCTGTCGTACCTGACGCTAACCAGGAAATGACTCTGGCCCGGCTAAGTCGTCCTCACGGTTGCAAGCTAATTCAGTGCATGATCTGCCTCTCACGTCACTCAAAGATCAATGATCTCAGGTCTCACATGAGCTCCCATCAATATGAACTAAGTTTTACTGAAGACAGAGATATTCCAAGTGCCTCGAGAGCCTTTTACCCAGATGTGGAAAGTACCTTAGAGCGAGATGAACTGGCCGGAAGGATTATGGCTGATGTGCAAAAGGAGTTTAACTTAGACCGCTTTATTTCCATCACAAACGAGGCCGGCCTGGAGCTGAGTCTCGATAGCAGCGAAACTGATACTGAGGCCGAGCAGGAGGAGGATCAGTCATCTTCAAACTATCCTTGCAACCTCTGTACGGTGGTTGTAAAGAGGAAGCATCAGCTGTATGCCCACCAACTGGAGGAGCACAAGTGGGAGGAGGCGCTCCTGGTATGTTCCAACTGCCAGGCTAGATTTGTCAATGAATCTTTGCTCGATCACCACTCCAGAACCCTTTGCCACAATCCGCAAAAACTCTTCCAGTGCCGCAAGTGTCCGCTTCGTTACCGCTGGCGGGACAATCTGAAGCTCCACATGGAAGTATTCCATCAGCTAGATGAGCTGTCAATCCAGAATGATTCACCCAAAGCAGATGGCGATCTGCAGTGCGGAAAGTGTCAGCGCAGTTTTAGGATGCAAAAGGATCTCACGCGTCATACATTAATGCACGGTCAGGAATCAAACATCTTCCGATGCCGTTGGTGTGCTCGTCGCTTTTATCGCAAAGCCAATCTTTTACAGCATATCGCACGTCATGGAATAAGTGTTAACCAGTTGCCGTACGCTGAGGCTATACTAGACTCATATGTGAATCCTGGAGGCCGAAAAAAGGTGGAGTGCCGAGTGTGCAACGTGAGCTTTCCCACCATCGCGGCTTTGCGACTGCATCTGGAAACCATGCCCGCCGGTAGTCACCACGACTACTCCTCGCTTCAAAACTACTCGATTACCAACCAAATGGGCTTTGAGATGGATTTGGATGATTCCGAgactgatgatgatgaggctAGGACACACACAAAACCACCAGGAGCTCCTGCCTCCTATACCTGCAATATGTGCCAACTGAGGTGTTTGCGGAAATTCGAGTTGTATCAACATCAGCAGGCTATGCACCGGATGGAGAAGATCTCCGACGGCTGTAATAGTTGCTTATTCAAGAGCGTCTGTCCGGAAATTATTTCCCACCACAAAAGAACTCAGTGCGAAAACCGAGAAAAGCAGTTCAAATGCACACGCTGCGGCTACAAGTTCATGTGGGAGTCAAACCTTTTGCAGCACATGGAGTTGCAGCATGAAAAGCCCGGGGATCTGGAGCTGGATGAGTCGAAGGAAGCGTCTGGTGACGAGCCAAAAGCCGAAGGTCAGGTCTTTCAGTGTGGACTTTGCACAAGGAAATACAACCGCAAGGATCGGTTAAGTGCGCACTTGAAAAAGTTCCATGGGCCCGACTGCAAACCGAATCCAGCGAAGACTTCAAACAGACCGATATCCCCTAAGGAACCAAAGCGTTTTCTGTGTGCTTTCTGCGGCAAGGCGGTCAGCTCTTCCTCCAACTTAATCATCCACATGCGTCGCCATACCGGTGAGAAGCCCTTCAAGTGCGAGTACTGCACCATGGCCTTTCCCCGATCCTCCGATCTCCAGTGCCACCGACGGACGCACACCGGCGAACGTCCACATGTATGCACGGTGTGTCAAAAGGGATTCGCCCGCTCCtacaagctgcagcagcacatGCGAATCCACAGCGGGGAGAGGCCCTACAAGTGCACCTACTGCGAGAAGAGCTTCACGCAATCCAACGACCTGACACTGCACATCCGGCGGCACACCGGCGAGCGTCCCTACCAATGCGGCGTCTGCGGAGAGCGTTTTATTCAGGGCACTGCTCTAAAGAACCACCGCATGCAGCAGAGCCACTACGAGGAGGGTCAGGAAACAGGACAGGAGCCCACGAGGCGCACGGTTCTGGAGCAGTTTACTCTATGA
Protein Sequence: MLPSDICRTCAVQNNQLLPLSTRLDRDASKSYYAVLQELTQIDLESSDDNLPQHLCPECWTRMEGAYAFVQQAKKVNGELLARLRECLDEMPIDIPAEQNIKTEVDLDDGGNKPGVEVDATETAALELKWQPESDSDQEFGAAPESDEDQVGKKSYHLRRSSRKVKQPVESENEECKPSEEPSPVKRRRGRPPGPAKSQAMTTDGRHACEVCGKTFSWYRDMQRHARIHFDNASYVCDTCGKGFLRKDKYIFHLRCHKKREAKWKALQLGKEWRFAERLYSSGRLKRVECKLCGSIFQQMEELRIHLRSHADVETLANLRRDSDVVREHFPGLPCDLDNIRQQICGDIAEGHLEKYACVVNFHGYELGLSDSDEDCDSKESKYHCLVCNMSFNRKHRLMRHTLEDHSQSATTLPWQRCSSCKVGFLCLTIYNKHLNTHCLSKIRRYRCRKCSGRFMWPENLQRHACSHHEEKTIASQIMCSLCETSLTSLSQLRLHLLTHQHDLNGINPAYNSMFFRSFYPDGLKCTISDLAVRIAEDFEVQDFDRYYNASTESGQELDLFESESELSDVETSKPSHICLLCGEVSSSLKILMQHQISAHSDGVTELPCHCEYCGSGFVSKALLQQHRRHRCEKKHSRFHCRVCNIWFIWESNYEKHQLTHHNKTKDGEEEPTKLKCDQCEKVFIWHKDLNRHKRLHQPQSAAQFDCPHCHRRFHRKDGLKSHLKVHAGNSDYVNNQPVVPDANQEMTLARLSRPHGCKLIQCMICLSRHSKINDLRSHMSSHQYELSFTEDRDIPSASRAFYPDVESTLERDELAGRIMADVQKEFNLDRFISITNEAGLELSLDSSETDTEAEQEEDQSSSNYPCNLCTVVVKRKHQLYAHQLEEHKWEEALLVCSNCQARFVNESLLDHHSRTLCHNPQKLFQCRKCPLRYRWRDNLKLHMEVFHQLDELSIQNDSPKADGDLQCGKCQRSFRMQKDLTRHTLMHGQESNIFRCRWCARRFYRKANLLQHIARHGISVNQLPYAEAILDSYVNPGGRKKVECRVCNVSFPTIAALRLHLETMPAGSHHDYSSLQNYSITNQMGFEMDLDDSETDDDEARTHTKPPGAPASYTCNMCQLRCLRKFELYQHQQAMHRMEKISDGCNSCLFKSVCPEIISHHKRTQCENREKQFKCTRCGYKFMWESNLLQHMELQHEKPGDLELDESKEASGDEPKAEGQVFQCGLCTRKYNRKDRLSAHLKKFHGPDCKPNPAKTSNRPISPKEPKRFLCAFCGKAVSSSSNLIIHMRRHTGEKPFKCEYCTMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHSGERPYKCTYCEKSFTQSNDLTLHIRRHTGERPYQCGVCGERFIQGTALKNHRMQQSHYEEGQETGQEPTRRTVLEQFTL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00548203;
90% Identity: iTF_00619276; iTF_00539791; iTF_00592521; iTF_00596784; iTF_00504818; iTF_00607922;
80% Identity: -