Basic Information

Insect: Drosophila mauritiana
Gene Symbol: -
Assembly: GCA_004382145.1
Location: NC:22269899-22274700[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 25 0.0067 0.41 10.8 0.9 1 23 206 228 206 228 0.96

2 25 1.3 79 3.6 2.9 1 19 234 252 234 256 0.80

3 25 0.085 5.2 7.4 0.5 2 20 288 306 287 309 0.94

4 25 0.013 0.77 10.0 5.4 1 23 382 405 382 405 0.94

5 25 0.28 17 5.7 2.1 1 23 445 467 445 467 0.97

6 25 0.0067 0.41 10.8 1.7 3 23 479 499 478 499 0.98

7 25 2.1 1.3e+02 3.0 0.2 1 23 576 599 576 599 0.92

8 25 0.0027 0.16 12.1 2.0 2 21 609 628 608 629 0.94

9 25 0.03 1.8 8.8 2.9 1 23 638 661 638 661 0.97

10 25 0.0066 0.4 10.9 2.2 2 23 675 696 674 696 0.97

11 25 0.00022 0.014 15.5 7.1 1 23 704 726 704 726 0.97

12 25 0.0012 0.072 13.2 0.9 1 23 864 887 864 887 0.95

13 25 0.039 2.4 8.4 3.3 2 23 895 918 894 918 0.91

14 25 0.0018 0.11 12.7 1.0 1 23 924 947 924 947 0.97

15 25 1.6e-05 0.001 19.1 2.1 2 23 966 987 965 987 0.97

16 25 0.00027 0.017 15.2 0.9 1 23 994 1016 994 1016 0.98

17 25 0.062 3.8 7.8 0.0 2 21 1043 1062 1042 1063 0.92

18 25 0.79 49 4.3 3.6 1 23 1113 1136 1113 1136 0.95

19 25 0.011 0.7 10.1 0.7 1 23 1173 1196 1173 1196 0.94

20 25 0.00054 0.033 14.3 2.7 1 23 1222 1245 1222 1245 0.98

21 25 4.7e-06 0.00029 20.7 0.2 2 23 1270 1291 1269 1291 0.95

22 25 0.00021 0.013 15.6 3.5 1 23 1297 1319 1297 1319 0.99

23 25 1.9e-06 0.00011 22.0 2.0 1 23 1325 1347 1325 1347 0.97

24 25 1.6e-07 1e-05 25.3 2.4 1 23 1353 1375 1353 1375 0.99

25 25 0.00084 0.051 13.7 0.2 1 22 1381 1402 1381 1405 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	25	0.0067	0.41	10.8	0.9	1	23	206	228	206	228	0.96
2	25	1.3	79	3.6	2.9	1	19	234	252	234	256	0.80
3	25	0.085	5.2	7.4	0.5	2	20	288	306	287	309	0.94
4	25	0.013	0.77	10.0	5.4	1	23	382	405	382	405	0.94
5	25	0.28	17	5.7	2.1	1	23	445	467	445	467	0.97
6	25	0.0067	0.41	10.8	1.7	3	23	479	499	478	499	0.98
7	25	2.1	1.3e+02	3.0	0.2	1	23	576	599	576	599	0.92
8	25	0.0027	0.16	12.1	2.0	2	21	609	628	608	629	0.94
9	25	0.03	1.8	8.8	2.9	1	23	638	661	638	661	0.97
10	25	0.0066	0.4	10.9	2.2	2	23	675	696	674	696	0.97
11	25	0.00022	0.014	15.5	7.1	1	23	704	726	704	726	0.97
12	25	0.0012	0.072	13.2	0.9	1	23	864	887	864	887	0.95
13	25	0.039	2.4	8.4	3.3	2	23	895	918	894	918	0.91
14	25	0.0018	0.11	12.7	1.0	1	23	924	947	924	947	0.97
15	25	1.6e-05	0.001	19.1	2.1	2	23	966	987	965	987	0.97
16	25	0.00027	0.017	15.2	0.9	1	23	994	1016	994	1016	0.98
17	25	0.062	3.8	7.8	0.0	2	21	1043	1062	1042	1063	0.92
18	25	0.79	49	4.3	3.6	1	23	1113	1136	1113	1136	0.95
19	25	0.011	0.7	10.1	0.7	1	23	1173	1196	1173	1196	0.94
20	25	0.00054	0.033	14.3	2.7	1	23	1222	1245	1222	1245	0.98
21	25	4.7e-06	0.00029	20.7	0.2	2	23	1270	1291	1269	1291	0.95
22	25	0.00021	0.013	15.6	3.5	1	23	1297	1319	1297	1319	0.99
23	25	1.9e-06	0.00011	22.0	2.0	1	23	1325	1347	1325	1347	0.97
24	25	1.6e-07	1e-05	25.3	2.4	1	23	1353	1375	1353	1375	0.99
25	25	0.00084	0.051	13.7	0.2	1	22	1381	1402	1381	1405	0.91

Sequence Information

Coding Sequence: ATGCTTCCGTCGGATATGTGCCGCACCTGTGCGGTGCAGAACAGCCAATTGCTGCCCTTGTCCACATGCTTGGACAGAGACGCCTCCAAAAGCTACTATGCGGTGCTCCGGGAATTGACGCAAATCGATCTGGAGAGCACCGATGATAACCTGCCGCAACATCTATGCACCGAGTGCTGGACACGAATGGAAAGTGCCTACGCCTTTGTGCAACAGGCCAGAAAAGTCAATGGAGAGCTGCTGGCTCGGTTAAGGGAATGTCTAGACGAAATGCCCATAGATATTCCCGCAGAGCAGAACATAAAAACGGAAGTAGACCTCGATGATGGCGGCAACAAGTCCGAAGTGGAAGTGGACGACACCGAAACGAGGGCTTTGGAACTCAAGTGGCAACCGGAGAGTGGCAGCGAACGGGAATTTTGTTCTGGTCCGGAAAGTGATGAAGATCAAGTGGAAAAGAAGTCGTATCATCTACGTCGAAGCTCCCGAAAAGTAAAGCAGCCAGTTGAAAGCGAAAACGAGGAATGTAAGCCATCTGAACCAACGCCGGTGAAGCGCCGTCGAGGACGCCCACCTGGTCCAGCGAAAAGCCAGGCGATGACCACGGATGGCCGGCACGCATGTGAGGTTTGCGAAAAAACATTCTCCTGGTACCGCGACATGCAGCGCCACGCCAGGATCCACTTCGAGAACGCTTCATACGTGTGCGATACCTGTGGCAAGGGATTTCTGCGCAAGGACAAGTACATATTCCATCTCCGATGCCACAAGAAGCGAGAGGCCAAATGGAAGGCTCTCCAGCTCGGGAAAGAGTGGCGTTTTGCTGAGCGCCTCTATAGCTCAGGCAGGTTGAAAAGAATCGAGTGCAAGCTATGCGGGTTGAGCTGCCAGCGAATGGAGGAGCTTAGATCTCATCTATGGGGTCACGCAGATGCAGAAACCTTAGTCAACTTGAGAACGGATAGTGACGTGGTAAGGGAGCATTTTCCTGGCTTGCCATGTGACTTGGACAATATTAAGCAACAGATTTGCGTTGACATAGCAGAAGGCAATTTGGAGAAGTATGCCTGTGTAGTGAATTTCCACGGATACGAGCTGGGACTCAGCGATTCCGACGAAGAGTGTGACAGCAAAGAGTCTAAATATCATTGCTTCGTGTGCAATATGTCTTTTAATCGCAAACATCGCCTGATGAAACACACCCTAGAGGATCACTCCCAATCTGCTACAACGCTGCCTTGGGAGAGATGCAGTTCCTGTAAAGTTGGTTTCCTGTGCCTAACGATGTACAACAAACATTTAAACACGCATTGCCAGAGCAAAATCCGAAGATATCGCTGCCGTAAATGTTCCGGGAGGTTTATGTGGCCGGAAAACCTCCAAAGACACGCGTGCTCGCACCGCGAGGAGAAAACGATTGCCAACCAAATATTGTGCTGTCTGTGCGATACCTCGCTATCTAGCTTATCGCAACTTCGCCTTCACTTAATCACACATCAACATGACTTAAATGGCATTAGTCCGGAGTACAATTCTTTGTTCTTTCGGTCGTTTTATCCTGACGGATTGAATTGCAGTATCTCAGATCTCGCTGTTCGTATAGCTGAGGATTTTGAGGTTCAGGACTTTGATCGCTACTATAACGCCAGTACCGAAAGTGGGCAGGAGCTTGATCTTTTTGAATCTGAAACAGAGTTGAGCGACGAGGAGACATCTAAAACATCGCACGTCTGTCTTTTGTGTGGAGAAACTTCGAATTCACTGATGATCCTGATGCAGCACCAAATAAGCTTACATTCTGATGGGGTGACTGAGCTTCCCTGCCGCTGCGAGTACTGTGGATCTGGCTTCGTAAGCAAAGCCCTCCTTCAACAACATCGTAGGCACCGTTGCGAAAAGAAACACTCCCGATTTCACTGCCGAGTATGTAATATCCGGTTCATATGGGAGTCGAACTATGAGAAACACCAGAAGACTTACCATAACAAAACGAAAGATGGAGAGGAACAGCCCACAAAGTTGAAGTGCGACCAGTGCGAAAAGGTATTCATTTGGCACAAGGATCTCAATCGGCACAAACGCCTGCATCAACCTCAGTCTGCTGCCCAGTTCGACTGTCCCCATTGCCATCGTAGGTTCCACCGCAAGGATGGCCTAAAGTCCCACCTTAAAGTGCACGCTGGAAATTCAGACTACATAAATAATCAGCCTGTCGTACCTGACGTTAACCAGGAAATGATTCTGGCCCGGCTAAGTCGTCCTCATGGTTGCAAGCTGATTCAGTGCATGATCTGCCTTTCACGCCACTCAAAGATCAGTGATCTAAGGTCTCACTTGAGTTCTCATCAATACGAACTGAATTTTACCGAAGACAGAGATATTCCGAGTGCCTCAAAAGCTTTTTACCCAGATCTGGAAAATACCCTAGAAAAAGATGAACTGGCCGAAATGATAATGGCTGATGTGCAAAGGGAATTCGACTTAGACCGCTTTATTTCTATCACAAACGAGGCCGGCCTGGAGCTGAATCTAGAAAGCAGCGAAACTGATACTGAGTCCGAGCAGGAGGAGAATCAGTCATCTTTAAACTATCCATGCAACCTCTGTACGACGGTTGTGAAGAGGAAGCATCAGCTGTATGCCCACCAACTGGAGGAGCACAAGTCGGAGGAGGCAGTCCTCGTATGTTCCAACTGCCAGACAAGATTTGTCAATGAATCTTTGCTCGATCACCACTCCAGAACCCTTTGCCACAATCCGCAAAAACTCTTTCAGTGCCGAAAGTGTCCGCTTCGTTTCCGCTGGCGGGAGAATCTGAAGCTCCATATGGAAGTATTCCATATGGTAGATGAACTTTCAATACAGGATGATTCGCCTAAAGCAGACGGCGATCTGCAGTGCGAAAAGTGCAATCGCAGTTTTAGGATGCAAAAGGATCTCACGCGCCATACACTAATGCACGGTCAGGAATCAAACATCTTCCGATGCCGTTGGTGCGCACGCCGCTTTTATCGTAGGGCCAATCTTTTACAGCATATCGCTCGTCACGGGATAAGTGTTAGCCAGTTGCCTTATGCTGAGGCCATACTGGACTCATATGTGAATCCTGGAGGCCGAAAAAAGGTGGAATGCCGAGTGTGCAACGTAAGCTTTCCCACTATCGCCGCTTTGCGACTTCATCTGGAAACTATGCCCGCCGGTAGTCACCACGACTACTCCTCACTTCAAAACTACTCAATTACTAACCAAATGGGTTTCGAGATGGATTTGTATGATTCTGAGACTGATGATGAAGACTCTAGGACACACATCAAACCACCAGGAGCGCCTTCCTCTTATACGTGCAATATGTGCCAACTAAGATGTTTACGGAAATTCGAGCTATATCAGCACCAGCAGGCTATGCACCGGATGGAGAAGATCTCCGACGGCTGTGATAGTTGCATTTTCAAGAGCGTCTGCCCGGAAATTATATCGCACCACAAAAGAACTCAGTGCGAAAACCGGGAAAAGCAGTTCAAATGCACACGCTGCGGATACAAGTTTATGTGGGAATCAAACCTTTTGCTACACATGGATTTGCAACATGTAAAAACAGAAGATCAGGAGCTGGATGAGTCAAAAGAAGCGTCAGGTGACGAGCCAAAAGCTGAAGGCCAGGTCTTTCAGTGTGGACTTTGTACAAGGAAATACAACCGGAAAGATCGGCTGACGGCTCACTTAAAAAAGTTCCATGGGCCCGACTGCAAACCGAATACAGCGAAGACTCCGAATAGACCCATATCACCTAAGGAACCAAAGCGGTTCCTGTGTGCTTTCTGCGGCAAGGCGGTCAGTTCTTCCTCCAACTTAATCATCCACATGCGTCGTCATACCGGTGAGAAGCCCTTCAAGTGCGAGTACTGCACTATGGCCTTCCCACGATCCTCTGATCTCCAGTGCCACCGACGTACGCACACCGGCGAACGTCCACATGTATGCACAGTGTGCCAGAAGGGATTCGCCCGCTCGTATAAACTGCAGCAGCACATGAGAATCCACAGCGGGGAGCGGCCCTACAAGTGCACCTACTGTGAGAAGAGCTTCACGCAATCCAACGACCTAACCCTGCACATCCGGCGGCACACTGGCGAGCGTCCATACCAATGTGGCGTCTGTGGAGAGCGCTTTATCCAGGGCACTGCTTTAAAGAACCATCGCATGCAGCAGAGCCATTACGAGGAGGGACAGGAATCGGTTGAGCCAACAAGGCGCACGGTTCTAGAGCAGTTTACCCTATGA
Protein Sequence: MLPSDMCRTCAVQNSQLLPLSTCLDRDASKSYYAVLRELTQIDLESTDDNLPQHLCTECWTRMESAYAFVQQARKVNGELLARLRECLDEMPIDIPAEQNIKTEVDLDDGGNKSEVEVDDTETRALELKWQPESGSEREFCSGPESDEDQVEKKSYHLRRSSRKVKQPVESENEECKPSEPTPVKRRRGRPPGPAKSQAMTTDGRHACEVCEKTFSWYRDMQRHARIHFENASYVCDTCGKGFLRKDKYIFHLRCHKKREAKWKALQLGKEWRFAERLYSSGRLKRIECKLCGLSCQRMEELRSHLWGHADAETLVNLRTDSDVVREHFPGLPCDLDNIKQQICVDIAEGNLEKYACVVNFHGYELGLSDSDEECDSKESKYHCFVCNMSFNRKHRLMKHTLEDHSQSATTLPWERCSSCKVGFLCLTMYNKHLNTHCQSKIRRYRCRKCSGRFMWPENLQRHACSHREEKTIANQILCCLCDTSLSSLSQLRLHLITHQHDLNGISPEYNSLFFRSFYPDGLNCSISDLAVRIAEDFEVQDFDRYYNASTESGQELDLFESETELSDEETSKTSHVCLLCGETSNSLMILMQHQISLHSDGVTELPCRCEYCGSGFVSKALLQQHRRHRCEKKHSRFHCRVCNIRFIWESNYEKHQKTYHNKTKDGEEQPTKLKCDQCEKVFIWHKDLNRHKRLHQPQSAAQFDCPHCHRRFHRKDGLKSHLKVHAGNSDYINNQPVVPDVNQEMILARLSRPHGCKLIQCMICLSRHSKISDLRSHLSSHQYELNFTEDRDIPSASKAFYPDLENTLEKDELAEMIMADVQREFDLDRFISITNEAGLELNLESSETDTESEQEENQSSLNYPCNLCTTVVKRKHQLYAHQLEEHKSEEAVLVCSNCQTRFVNESLLDHHSRTLCHNPQKLFQCRKCPLRFRWRENLKLHMEVFHMVDELSIQDDSPKADGDLQCEKCNRSFRMQKDLTRHTLMHGQESNIFRCRWCARRFYRRANLLQHIARHGISVSQLPYAEAILDSYVNPGGRKKVECRVCNVSFPTIAALRLHLETMPAGSHHDYSSLQNYSITNQMGFEMDLYDSETDDEDSRTHIKPPGAPSSYTCNMCQLRCLRKFELYQHQQAMHRMEKISDGCDSCIFKSVCPEIISHHKRTQCENREKQFKCTRCGYKFMWESNLLLHMDLQHVKTEDQELDESKEASGDEPKAEGQVFQCGLCTRKYNRKDRLTAHLKKFHGPDCKPNTAKTPNRPISPKEPKRFLCAFCGKAVSSSSNLIIHMRRHTGEKPFKCEYCTMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHSGERPYKCTYCEKSFTQSNDLTLHIRRHTGERPYQCGVCGERFIQGTALKNHRMQQSHYEEGQESVEPTRRTVLEQFTL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00548203;
90% Identity: iTF_00591827;
80% Identity: -