Dpse004105.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila pseudoananassae
Gene Symbol
ZFY
Assembly
GCA_018153035.1
Location
JAECXR010000044.1:198640-200330[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 2.8e-05 0.002 18.3 0.8 1 23 96 118 96 118 0.97
2 11 1.9e-07 1.3e-05 25.1 1.2 1 23 124 147 124 147 0.97
3 11 6.6e-06 0.00047 20.3 0.3 1 23 153 175 153 175 0.97
4 11 1.4e-05 0.001 19.2 0.5 1 23 181 203 181 204 0.95
5 11 1.3e-06 9e-05 22.5 0.9 1 23 211 233 211 233 0.97
6 11 0.0037 0.26 11.6 1.1 1 23 239 262 239 263 0.95
7 11 0.022 1.6 9.2 0.1 3 23 270 290 268 290 0.96
8 11 1.6 1.1e+02 3.4 0.3 14 23 293 302 292 302 0.91
9 11 1.6e-05 0.0011 19.1 4.7 1 23 308 330 308 330 0.99
10 11 0.0014 0.099 13.0 1.2 1 23 336 361 336 361 0.96
11 11 0.0024 0.17 12.2 0.1 1 19 367 385 367 387 0.95

Sequence Information

Coding Sequence
ATGGTACGCAGTCGTCGCAGTTTGTCCAAGGAGGATGCCGTCTCCCTGCATACAGACAGCGGTATCTCGCTCTCCTCGCCGCCCACGGATCGATGTTCGTCCCCGGTTCTTGTCACACCAGCGGCCATCAAGCGGCGGAAGAGCAGCTTGGCCAGTTTGCGGGACACCTGTGCGGATGAGGACGAAGAAGGTGCTGGCGAGCAGGACTTGAAAGATGCCGACTACATCCAGCCTCCGCCGAAGAAGGCTATCCGCGGAAAGCCAGAAGTCGTGAAACGGAAGCACCACGTCTGCAGCCTATGTTCCAAGGAGTTTGGCGGCAAAACGGACTTGCAGCGCCACATGCTCATCCACTCGGACGAGCGGCCGCACAAGTGCTCCGTTTGCGGGAAGAGCTACCGCCAGGCGGTCAACCTGAAGAACCATATCACCACCGCCCACGAGCACCGCAAGCAGTTTGCCTGCCCCCAGTGCCCCAAGTCTTTCGCCCTGAAAGAACGCCTGCGCCTCCACATGCGACTCCACTCCGGCGAGAAGCCCTATCCGTGTGCTCTATGCGACAAAAAGTTTGCCAGAGGTGGACAGCTTCAGCAACATATGGTTTCGCACCACAAGACCAGTATTCAGCAATTCAATTGCACCAAGTGCTCGGCCAGCTTCTCCACGAACGCCAATCTTCGGGTCCACATGGAAAGGCATGAGCAGGGCATGGAGCATCGATGCCAAGTCTGCGATAGCCAGTTTGCGAACGAGTTAGCCCTGCGTGCCCACATCAACCAGGAACACCACAAGCTCACGCAGCTCGACTGTGAGGTCTGCCACAAGGCTATCGAACCGGATGAGGATCTTGCCACTCATATGCAAAAGCACGCGGCGAGCCAGTACAATGTCCACATGCGAATGCACACGGGAGAGCGACCGTACCAGTGCAGGATCTGCCATCAGACGTTTGCCCACTCCAGCGTTTTAAAGCTGCACATCCGCAAGCACACTGGCGAGAAACCATTTCGCTGTCAGCTGTGCCAGGACGAAGTAGCCTTCTCGCAACTGGCGCACCTCAAGAACCACATGAAGAAGATCCACAAGCAGCAGAAGCCGTACATGTGCGAAGGCTGCCACGAGTTCTTTAAGATCAAGGTGGAGCTGCAGGCGCATGCTGAGCAATGCGCCAAATGCCCTGGAAGTGGAGGCGATGCGGTAGATCCGCAGTCCGATGATTCGCTGGTACTCTCCAGAATCCGCTTCAATATGGCGGTGGTGCTGAAGAAGATAAGCTCGGCCCAGAAGCTGCGCCAGTTGGGTTATGAAAAGCGTCTGATTGATAATGTGGTCATTGCGTCTCTGAAGCTGGCCCAACGAACCACACACGACGACGTCAAGCTGACACCCCTGGCAAGGTTGCGCCTGAATGTTGAGGAGTTCCTCAAGTGGATCGTGCCGGCACCCACAATGAAGAAATTCAGCGAAGAGATGCTGTCCGTTGACACCATTCTCGATAAGATTGCGACCATGTATATGAAGCAGAAGTAG
Protein Sequence
MVRSRRSLSKEDAVSLHTDSGISLSSPPTDRCSSPVLVTPAAIKRRKSSLASLRDTCADEDEEGAGEQDLKDADYIQPPPKKAIRGKPEVVKRKHHVCSLCSKEFGGKTDLQRHMLIHSDERPHKCSVCGKSYRQAVNLKNHITTAHEHRKQFACPQCPKSFALKERLRLHMRLHSGEKPYPCALCDKKFARGGQLQQHMVSHHKTSIQQFNCTKCSASFSTNANLRVHMERHEQGMEHRCQVCDSQFANELALRAHINQEHHKLTQLDCEVCHKAIEPDEDLATHMQKHAASQYNVHMRMHTGERPYQCRICHQTFAHSSVLKLHIRKHTGEKPFRCQLCQDEVAFSQLAHLKNHMKKIHKQQKPYMCEGCHEFFKIKVELQAHAEQCAKCPGSGGDAVDPQSDDSLVLSRIRFNMAVVLKKISSAQKLRQLGYEKRLIDNVVIASLKLAQRTTHDDVKLTPLARLRLNVEEFLKWIVPAPTMKKFSEEMLSVDTILDKIATMYMKQK