Basic Information

Gene Symbol
-
Assembly
GCA_018904565.1
Location
JAEIHY010018453.1:2597-4305[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 5.1e-05 0.0051 17.5 2.2 1 23 95 117 95 117 0.96
2 11 1.2e-07 1.2e-05 25.8 1.6 1 23 123 146 123 146 0.97
3 11 1.3e-05 0.0013 19.3 0.9 1 23 152 174 152 174 0.98
4 11 1.5e-05 0.0015 19.2 0.5 1 23 180 202 180 203 0.95
5 11 1.3e-06 0.00013 22.5 0.9 1 23 210 232 210 232 0.97
6 11 0.006 0.6 11.0 1.0 1 23 238 261 238 262 0.95
7 11 0.00081 0.081 13.7 0.2 1 23 267 289 267 289 0.98
8 11 1.8e-05 0.0018 18.9 2.7 1 23 295 317 295 317 0.98
9 11 1.6e-05 0.0016 19.1 4.7 1 23 323 345 323 345 0.99
10 11 0.0016 0.16 12.8 0.9 1 23 351 376 351 376 0.95
11 11 0.0032 0.32 11.8 0.2 1 19 382 400 382 402 0.96

Sequence Information

Coding Sequence
ATGGTACGCAGTCGTCGTAGCTTGTCCAAGGAGGATGCTGTGTCCCTGCTTACGGACAGTGGCATCTCGCTATCCTCGCCGCCGGCGGCACGAGATTCTTCGCCCACGCCAATCACCACACCCACCTCCATAAAGAGGCGGAAAAGCAGCTTGGCCAGTCTACGAGATGCCTGCACCGAGGATGACGAAGAAGCAGCCGATCAGGACTCCAAGGACGCCGACTATGTGCAGCCACCGCCAAAGAAGTCCCCACGCAAGGCAGAGACCGGAAAGCGAAAGCTTCATATCTGCAACCACTGCTCCAAGGAGTTTGGCGGCAAGACGGACCTGCAGCGCCACATACTCATCCATTCGGACGAAAGGCCCCACAAGTGCAAGGAGTGCGGGAAGAGCTACCGCCAGGCAGTGAACCTCAAGAACCACATTACCACCGCCCATGAGCACCGAAAGCAGTTCTCTTGCTCCCAGTGCCCCAAGTCGTTCGCCCTCAAGGAGCGCCTGCGCCTGCACATGCGACTCCACTCCGGCGAGAAGCCGTATCCGTGCGCCCTGTGCGACAAGAAATTCGCCAGGGGAGGCCAGCTCCAGCAGCACATGGTATCGCACCACAAGACCAGCATCCAGCAGTTCAACTGTACCAAGTGCTCGGCCAGCTTCTCAACGAACGCCAACCTGCGGGTGCACATGGAACGCCACGAGCAGGGCATGGAGCACCGTTGCAGCATCTGCGAGAGCCAGTTTGCCAACGAGCTGGCCCTGCGAGCCCATATCAATCAGGAGCATCACAAGCTAACGCAGTTCGAGTGCGAAATCTGTCACAAGACCATCGAGCCGGACGAGGATCTGGCCACGCACATGCAGAAGCATGCGGCGGTTAAAACGCATGTCTGCGAAGTGTGCAACTCGTACTTTACCCAGAAGAGTCAGTACAATGTCCACATGCGAATGCATACGGGCGAGCGGCCCTACCAGTGTCGAATCTGCCATCAGACTTTTGCCCACTCCAGCGTACTGAAGCTGCACATCCGCAAGCACACGGGAGAGAAACCCTTCCGCTGCCAGCTGTGCGAGGATGAGGTGGCCTTCTCCCAGCTGGCGCATCTGAAGAACCACATGAAGAAGATTCACAAGCAGCAGAAGCCGTACATGTGCGAGGGCTGCCACGAGTTCTTCAAAATCAAGGTGGAGCTGCAGGCGCATTCGGAACAGTGTGTCAAGTGTCCTGCGGGCGGGGACGAGTCCACCGACAGCCAATCCGTGGATGCGGTGATCCTCTCCACAATGCGCTTTAATATAGCCGTGGTGCTAAAGAAAATAAGCTCAGCGCAGAAGCTACGCCAATTGGGCTACGAGAAGCGTCTCATAGACAATGTGATCATAGCATCTCTGAAGCTGGCCCAAAGGCCCACGCACGACGACGCCAAACTGACGCCCCTATCCCGGCTTCGCCTGAATGTGGAGGAGTTCCTCAAGTGGATTGTGCCGGCGCCAACAATGAAGAAGTTCAGCGAGGAGATGCTGTCCATCGACACCATTCTCGACAAGATTGCCACCATGTATATGAAGCAGAAGTAG
Protein Sequence
MVRSRRSLSKEDAVSLLTDSGISLSSPPAARDSSPTPITTPTSIKRRKSSLASLRDACTEDDEEAADQDSKDADYVQPPPKKSPRKAETGKRKLHICNHCSKEFGGKTDLQRHILIHSDERPHKCKECGKSYRQAVNLKNHITTAHEHRKQFSCSQCPKSFALKERLRLHMRLHSGEKPYPCALCDKKFARGGQLQQHMVSHHKTSIQQFNCTKCSASFSTNANLRVHMERHEQGMEHRCSICESQFANELALRAHINQEHHKLTQFECEICHKTIEPDEDLATHMQKHAAVKTHVCEVCNSYFTQKSQYNVHMRMHTGERPYQCRICHQTFAHSSVLKLHIRKHTGEKPFRCQLCEDEVAFSQLAHLKNHMKKIHKQQKPYMCEGCHEFFKIKVELQAHSEQCVKCPAGGDESTDSQSVDAVILSTMRFNIAVVLKKISSAQKLRQLGYEKRLIDNVIIASLKLAQRPTHDDAKLTPLSRLRLNVEEFLKWIVPAPTMKKFSEEMLSIDTILDKIATMYMKQK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00580113;
90% Identity
iTF_00490210;
80% Identity
-