Basic Information

Insect: Drosophila ochracea
Gene Symbol: lrrfip2
Assembly: GCA_035044125.1
Location: JAWNML010000021.1:4046277-4050100[-]

Transcription Factor Domain

TF Family: LRRFIP
Domain: LRRFIP domain
PFAM: PF09738
TF Group: Unclassified Structure
Description: LRRFIP1 is a transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'- AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA [1]. LRRFIP2 may function as activator of the canonical Wnt signalling pathway, in association with DVL3, upstream of CTNNB1/beta-catenin [2].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 2 4.4e-119 7.3e-115 383.3 22.1 1 299 30 321 30 322 0.99

2 2 0.033 5.6e+02 -0.5 3.5 210 241 341 371 324 395 0.55

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	2	4.4e-119	7.3e-115	383.3	22.1	1	299	30	321	30	322	0.99
2	2	0.033	5.6e+02	-0.5	3.5	210	241	341	371	324	395	0.55

Sequence Information

Coding Sequence: ATGGACAACACAAGTGCCACTGGTCGGCGACGGAACAATATATGTGTTAATGCCGAGGATAATGCGCTCGATCAAATTACAAAGGAGGCGGAAGCGCGGTTAGCAGCTCGTCGACAAGCTCGTGCCGAGGCACGTGAAATACGCATGCGAGAGCTTGAGCGGCAACAAAAGGAGCAAGAACAAAATGCTGACCGCGCATTTGACATGCATAACACCAGTGCTGGTGTTATTATCGACACTGTCTCATCACACCCCCCACGTAATACCTACGGCGGTCTAATAAACTTAACGCGCGCAACAGCTTCGAGACGCAGTAGTGAGGATTCATTGGAGGATGAAGGTCGCAGTTTGCGTGATATTAAATTTGAGCTTAAGGATGTCGAAGAACGTTTCCGAAAAGCGATGATAACGAATGCCCAGCTTGACAACGACCGCTCATCTCAAACCTATGAAGTGAAGTTACTCAAAGATAAAGGTGAAACAATGCAAGAgtcttttgcacaacttcaacgtgagcttaaaaataaattacggGATTGTAATGCCCTGAAACGGAACTTGGACCGCACAACACTTGAATTGAACCTAGTGCAAGGTCAGCTAACCGAGCGTGATGCACTAATAGCGGAACATGgccttgttattgttgccattgagAATACTGATGGTACTGATGCCAAGAGGGCTTTACTCAGTGTTGAAAACGCCAATACCTTGGCGACAGTGCAGGGTTCGCTTGATATAAGACTTAAAAAGTTGGCAGAAGAAAAACAACGAGTTTTGAGCGAAATGCAAAATCTTCGTGAACAATTGGATGCGTATAAGAGTGATGGTCGGGGTGGACGCGGCAGTTCATTGAATGGTCCCGTAGgttatgatgatgattacgAAGTTCAAAgagaagcaaataaaatcatatcAGATTATAAATACAAGCTACAAAAGGCTGAACAGGAAATCGCTAGTCTTCAGGCAAGCTTATCACGCTCGGAGACACAAGTTATACGATATAAAAGTACGGCAGAAGCAGCCGAAAAAGCAGAGGCAGAACTAAAAGTCGAACGACGTAAACTTCAACGTGAACACCGGGAGATTCTGGAACGTTTGGAAGAATCTGAAACCGCTAATAACCATCTACTAAAACGTCTTGATAAACTAAAAAATGCTAAGAGCACGATTTTAAAGGACTTATGA
Protein Sequence: MDNTSATGRRRNNICVNAEDNALDQITKEAEARLAARRQARAEAREIRMRELERQQKEQEQNADRAFDMHNTSAGVIIDTVSSHPPRNTYGGLINLTRATASRRSSEDSLEDEGRSLRDIKFELKDVEERFRKAMITNAQLDNDRSSQTYEVKLLKDKGETMQESFAQLQRELKNKLRDCNALKRNLDRTTLELNLVQGQLTERDALIAEHGLVIVAIENTDGTDAKRALLSVENANTLATVQGSLDIRLKKLAEEKQRVLSEMQNLREQLDAYKSDGRGGRGSSLNGPVGYDDDYEVQREANKIISDYKYKLQKAEQEIASLQASLSRSETQVIRYKSTAEAAEKAEAELKVERRKLQREHREILERLEESETANNHLLKRLDKLKNAKSTILKDL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00336724;
90% Identity: iTF_00501795; iTF_00511267; iTF_00553028; iTF_00560260; iTF_00582949; iTF_00528038; iTF_00535302; iTF_00552295; iTF_00597351; iTF_00513449; iTF_00500300; iTF_00496589; iTF_00482223; iTF_00498864; iTF_00607056; iTF_00570385; iTF_00576337; iTF_00522162; iTF_00557202; iTF_00609874; iTF_00516980; iTF_00543733; iTF_00619830; iTF_00574039; iTF_00499576; iTF_00514168; iTF_00485850; iTF_00548794; iTF_00598874; iTF_00616187; iTF_00558652; iTF_00525118; iTF_00542430; iTF_00566782; iTF_00495103; iTF_00518431; iTF_00521343; iTF_00595935; iTF_00497376;
80% Identity: -