Dkam005893.1
Basic Information
- Insect
- Drosophila kambysellisi
- Gene Symbol
- lrrfip2
- Assembly
- GCA_035042185.1
- Location
- JAWNLS010000691.1:661318-664837[-]
Transcription Factor Domain
- TF Family
- LRRFIP
- Domain
- LRRFIP domain
- PFAM
- PF09738
- TF Group
- Unclassified Structure
- Description
- LRRFIP1 is a transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'- AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA [1]. LRRFIP2 may function as activator of the canonical Wnt signalling pathway, in association with DVL3, upstream of CTNNB1/beta-catenin [2].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 8.1e-120 1.5e-115 385.7 24.1 1 299 30 321 30 322 0.99 2 2 0.033 6.2e+02 -0.5 3.5 210 241 341 371 324 395 0.55
Sequence Information
- Coding Sequence
- ATGGACAACACAAGTGCCACTGGTCGGCGACGGAACAATATATGTGTTAATGCCGAGGATAATGCGCTTGATCAAATTACAAAGGAGgCGGAAGCGCGCTTAGCAGCTCGTCGACAAGCTCGTGCTGAAGCACGTGAGATACGCATGCGAGAGCTTGAGCGGCAACAAAaggaacaagaacaaaatGCTGACCGCGCATTTGACATGCATAACACCAGTGCTGGTGTTATTATCGACACTGTCTCATCACACCCCACACGTAATACCTACGGCGGTCTAATAAACTTAACGCGCGCAACCGCTTCGAGACGCAGCAGTGAGGATTCATTGGAGGACGAAGGTCGCAGTTTGCGTGATATTAAATACGAGCTTAAGGATGTCGAAGAACGTTTCCGAAAAGCGATGATAACAAATGCCCAGCTTGACAACGACCGCTCATCTCAAACCTATGAAGTGAAGTTACTCAAAGATAAAAGTGAAACAATGCAAGAgtcttttgcacaacttcaacGTGagctgaaaaataaattgcgtGATTGTAATGCCCTGAAACGCAACTTGGACCGCACAACACTTGAATTGGGCCTAGTGCAAGGCCAGCTTAACGAGCGTGATGCACTAATTGCGGAACATGgccttgttattgttgccattgAGAATACTGATGGTAGTGATGCCAAGAGGGCACTACTCAGTGTTGAAAACGCCAATACCTTGGCGACAGTGCAAGGTTCGCTTGATATAAGACTCAAGAAGTTGGCAGAAGAAAAACAACGGCTTTTGAACGAAATGCAAAATCTTCGTGAACAGTTGGATGCTTATAAGAGTGATGGCCGGGGTGGACGCGGTAATTCATTGAATGGCCCGGTAGGTTATGATGATGATTACGAGGTTCAAAGagaagcaaataaaatcatatcAGATTATAAATACAAGCTACAAAAGGCTGAACAGGAAATCGCTAGTCTTCAGGCAAGCTTATCACGCTCGGAGACACAAGTTATACGATATAAAAGCACGGCAGAAGCAGCCGAAAAGGCCGAGGCCGAACTAAAAGTCGAGCGACGTAAACTGCAACGTGAACACCGGGAGATTCTGGAACGTTTGGAAGAATCTGAAACCGCTAATAACCATCTACTAAAACGTCTTGATAAACTAAAAAATGCTAAGAGCACGATTTTAAAGGACTTATGA
- Protein Sequence
- MDNTSATGRRRNNICVNAEDNALDQITKEAEARLAARRQARAEAREIRMRELERQQKEQEQNADRAFDMHNTSAGVIIDTVSSHPTRNTYGGLINLTRATASRRSSEDSLEDEGRSLRDIKYELKDVEERFRKAMITNAQLDNDRSSQTYEVKLLKDKSETMQESFAQLQRELKNKLRDCNALKRNLDRTTLELGLVQGQLNERDALIAEHGLVIVAIENTDGSDAKRALLSVENANTLATVQGSLDIRLKKLAEEKQRLLNEMQNLREQLDAYKSDGRGGRGNSLNGPVGYDDDYEVQREANKIISDYKYKLQKAEQEIASLQASLSRSETQVIRYKSTAEAAEKAEAELKVERRKLQREHREILERLEESETANNHLLKRLDKLKNAKSTILKDL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00336724;
- 90% Identity
- iTF_00564641;
- 80% Identity
- iTF_00522162;