Ddif013739.1
Basic Information
- Insect
- Drosophila differens
- Gene Symbol
- Lrrfip2
- Assembly
- GCA_037043665.1
- Location
- JBAMAZ010000301.1:1746827-1750338[+]
Transcription Factor Domain
- TF Family
- LRRFIP
- Domain
- LRRFIP domain
- PFAM
- PF09738
- TF Group
- Unclassified Structure
- Description
- LRRFIP1 is a transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'- AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA [1]. LRRFIP2 may function as activator of the canonical Wnt signalling pathway, in association with DVL3, upstream of CTNNB1/beta-catenin [2].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 5.3e-119 4.7e-115 384.0 22.2 1 299 30 321 30 322 0.99 2 2 0.067 5.8e+02 -0.5 3.5 210 241 341 371 324 395 0.55
Sequence Information
- Coding Sequence
- ATGGACAACACAAGTGCCACTGGTCGGCGACGGAACAATATATGTGTTAATGCCGAGGATAATGCGCTCGATCAAATTACAAAGGAGGCGGAAGCGCGGCTAGCAGCTCGTCGACAAGCTCGTGCCGAGGCGCGTGAGATACGCATGCGAGAGCTTGAGCGGCAACAAAAGGAGCAAGAACAAAATGCTGATCGCGCATTTGACATGCATAACACCAGTGGGGGTGTTATTATCGACACTGTCTCATCACACCCCACACGTAATACCTACGGCGGTCTAATAAACTTAACGCGCGCAACAGCTTCGAGACGCAGTAGTGAGGATTCATTGGAGGACGAAGGTCGCAGTTTGCGTGATATTAAATACGAGCTTAAGGATGTCGAAGAACGTTTCCGAAAAGCGATGATAACGAATGCCCAGCTTGACAACGACCGCTCATCTCAAACCTATGAAGTGAAGTTACTCAAAGATAAAGGTGAAACAATGCAAGAgtcttttgcacaacttcaacgtgagcttaaaaataaattaagggATTGTAATGCCCTGAAACGCAACTTGGACCGCACAACACTTGAATTGAACCTAGTACAAGGCCAGCTAACCGAGCGTGACACACTAATAGCGGAACATGgccttgttattgttgccattgaGAATACTGATGGTACTGATGCCAAGAGGGCTCTACTCAGTGTTGAAAACGCCAATACCTTGGCGACAGTGCAGGGTTCGCTTGATATAAGACTCAAAAAGTTGGCAGAAGAAAAACAACGACTTTTGAGCGAAATGCAAAGTCTTCGTGAACAATTGGAGGCGTATAAGTGTGATGGTCGGGGTGGACGTGGCAGCTCATTGAATGGTCCCGTAGGTTATGATGATGATTACGAAGTTCAAAgagaagcaaataaaatcatatcAGATTATAAATACAAGCTACAAAAGGCTGAACAGGAGATCGCTAGTCTTCAGGCAAGCTTATCACGCTCGGAGACACAAGTTATACGATATAAAAGCACGGCAGAAGCAGCCGAAAAAGCAGAGGCAGAACTAAAAGTCGAACGACGTAAACTCCAACGTGAACACCGGGAGATTCTGGAACGTTTAGAAGAATCTGAAACCGCTAATAACCATCTACTGAAACGTCTTGATAAACTAAAAAATGCTAAGAGCACGATTTTAAAGGACTTATGA
- Protein Sequence
- MDNTSATGRRRNNICVNAEDNALDQITKEAEARLAARRQARAEAREIRMRELERQQKEQEQNADRAFDMHNTSGGVIIDTVSSHPTRNTYGGLINLTRATASRRSSEDSLEDEGRSLRDIKYELKDVEERFRKAMITNAQLDNDRSSQTYEVKLLKDKGETMQESFAQLQRELKNKLRDCNALKRNLDRTTLELNLVQGQLTERDTLIAEHGLVIVAIENTDGTDAKRALLSVENANTLATVQGSLDIRLKKLAEEKQRLLSEMQSLREQLEAYKCDGRGGRGSSLNGPVGYDDDYEVQREANKIISDYKYKLQKAEQEIASLQASLSRSETQVIRYKSTAEAAEKAEAELKVERRKLQREHREILERLEESETANNHLLKRLDKLKNAKSTILKDL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00336724;
- 90% Identity
- iTF_00564641;
- 80% Identity
- -